Project
PRJNA195909:zebrafish embryo and larva development
Navigation
Downloads
Results for hoxc13b+hoxd13a
Z-value: 1.63
Motif logo
Transcription factors associated with hoxc13b+hoxd13a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxc13b | dr11_v1_chr11_+_2156430_2156430 | -0.70 | 3.7e-02 | Click! |
| hoxd13a | dr11_v1_chr9_-_1990323_1990323 | -0.64 | 6.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_4245311 Show fit | 3.56 |
ENSDART00000055379
|
growth differentiation factor 3 |
|
| chr4_-_77551860 Show fit | 3.34 |
ENSDART00000188176
|
|
|
| chr19_-_27550768 Show fit | 3.13 |
ENSDART00000142313
|
si:dkeyp-46h3.8 |
|
| chr7_-_48263516 Show fit | 2.79 |
ENSDART00000006619
ENSDART00000142370 ENSDART00000148273 ENSDART00000147968 |
RNA binding protein with multiple splicing 2b |
|
| chr17_-_4245902 Show fit | 2.74 |
ENSDART00000151851
|
growth differentiation factor 3 |
|
| chr18_-_43866001 Show fit | 2.58 |
ENSDART00000150218
|
trehalase (brush-border membrane glycoprotein) |
|
| chr1_+_24387659 Show fit | 2.57 |
ENSDART00000130356
|
quinoid dihydropteridine reductase b2 |
|
| chr18_-_43866526 Show fit | 2.26 |
ENSDART00000111309
|
trehalase (brush-border membrane glycoprotein) |
|
| chr14_-_8940499 Show fit | 2.16 |
ENSDART00000129030
|
zgc:153681 |
|
| chr3_+_23045214 Show fit | 2.12 |
ENSDART00000157090
ENSDART00000156472 |
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxc13b+hoxd13a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 6.3 | GO:1900145 | nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) |
| 1.6 | 4.8 | GO:0005991 | trehalose metabolic process(GO:0005991) |
| 0.7 | 3.4 | GO:0060368 | regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
| 0.1 | 3.4 | GO:0099515 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
| 0.2 | 3.3 | GO:0051445 | regulation of meiotic cell cycle(GO:0051445) |
| 0.6 | 2.8 | GO:0051148 | smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148) |
| 0.0 | 2.7 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.3 | 2.6 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.0 | 2.6 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.0 | 2.3 | GO:0016575 | histone deacetylation(GO:0016575) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0005769 | early endosome(GO:0005769) |
| 0.1 | 3.6 | GO:0043186 | P granule(GO:0043186) |
| 0.0 | 2.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 2.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 2.4 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.1 | 2.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 2.1 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 2.0 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 1.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.5 | 1.8 | GO:1904423 | dehydrodolichyl diphosphate synthase complex(GO:1904423) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.0 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 5.4 | GO:0005125 | cytokine activity(GO:0005125) |
| 1.6 | 4.8 | GO:0015927 | alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927) |
| 0.1 | 3.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 3.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 3.3 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.0 | 2.8 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.6 | 2.6 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404) |
| 0.1 | 2.5 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 2.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 3.4 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 2.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.8 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 1.7 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 1.4 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 1.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.2 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.8 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.7 | 3.4 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 0.1 | 2.3 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 1.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.5 | REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION | Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
| 0.1 | 1.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 1.4 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.3 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 1.2 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |