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PRJNA195909:zebrafish embryo and larva development

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Results for hoxc13b+hoxd13a

Z-value: 1.63

Motif logo

Transcription factors associated with hoxc13b+hoxd13a

Gene Symbol Gene ID Gene Info
ENSDARG00000059256 homeobox D13a
ENSDARG00000113877 homeobox C13b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc13bdr11_v1_chr11_+_2156430_2156430-0.703.7e-02Click!
hoxd13adr11_v1_chr9_-_1990323_1990323-0.646.6e-02Click!

Activity profile of hoxc13b+hoxd13a motif

Sorted Z-values of hoxc13b+hoxd13a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_4245311 3.56 ENSDART00000055379
growth differentiation factor 3
chr4_-_77551860 3.34 ENSDART00000188176

chr19_-_27550768 3.13 ENSDART00000142313
si:dkeyp-46h3.8
chr7_-_48263516 2.79 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr17_-_4245902 2.74 ENSDART00000151851
growth differentiation factor 3
chr18_-_43866001 2.58 ENSDART00000150218
trehalase (brush-border membrane glycoprotein)
chr1_+_24387659 2.57 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr18_-_43866526 2.26 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr14_-_8940499 2.16 ENSDART00000129030
zgc:153681
chr3_+_23045214 2.12 ENSDART00000157090
ENSDART00000156472
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr22_-_22164338 2.06 ENSDART00000183840
cell division cycle 34 homolog (S. cerevisiae) a
chr24_-_10393969 2.02 ENSDART00000106260
ANKH inorganic pyrophosphate transport regulator a
chr10_+_6884627 1.99 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr25_+_4787431 1.97 ENSDART00000170640
myosin VC
chr25_-_20666754 1.97 ENSDART00000158418
C-terminal Src kinase
chr24_+_34069675 1.90 ENSDART00000143995
si:ch211-190p8.2
chr1_-_27014872 1.86 ENSDART00000147414
ENSDART00000134032
ENSDART00000192087
ENSDART00000189111
ENSDART00000187348
ENSDART00000187248
centlein, centrosomal protein
chr14_+_26247319 1.82 ENSDART00000192793
coiled-coil domain containing 69
chr25_+_4787607 1.79 ENSDART00000159422
myosin VC
chr5_+_66132394 1.75 ENSDART00000073892
zgc:114041
chr14_+_16083818 1.70 ENSDART00000168462
ring finger protein 103
chr14_+_35464994 1.68 ENSDART00000115307
si:ch211-203d1.3
chr3_+_43102010 1.68 ENSDART00000162096
mical-like 2a
chr2_+_37295088 1.64 ENSDART00000056519
G protein-coupled receptor 160
chr18_-_25051846 1.63 ENSDART00000013082
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr17_-_41798856 1.62 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr1_+_10129099 1.58 ENSDART00000187740
RNA binding motif protein 46
chr24_+_5799764 1.57 ENSDART00000154482
si:ch211-157j23.2
chr16_+_32736588 1.57 ENSDART00000075191
ENSDART00000168358
zgc:172323
chr2_-_37353098 1.56 ENSDART00000056522
SKI-like proto-oncogene a
chr20_-_32007209 1.56 ENSDART00000021575
androglobin
chr2_-_6373829 1.55 ENSDART00000081633
si:dkey-119f1.1
chr17_+_8754020 1.55 ENSDART00000105322
erythroid differentiation regulatory factor 1
chr15_-_20412286 1.54 ENSDART00000008589
calcineurin-like EF-hand protein 2
chr19_+_40122160 1.53 ENSDART00000143966
si:ch211-173p18.3
chr23_-_35347714 1.50 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr8_-_410728 1.49 ENSDART00000151255
tripartite motif containing 36
chr3_-_25268751 1.45 ENSDART00000139423
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr20_-_2713120 1.44 ENSDART00000138753
ENSDART00000104606
arginyl-tRNA synthetase 2, mitochondrial (putative)
chr25_-_20666328 1.44 ENSDART00000098076
C-terminal Src kinase
chr23_-_24343363 1.43 ENSDART00000166392
family with sequence similarity 131, member C
chr16_+_7380463 1.41 ENSDART00000029727
ENSDART00000149086
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr22_+_35205968 1.41 ENSDART00000150467
TSC22 domain family 2
chr12_-_27212880 1.40 ENSDART00000002835
proteasome activator subunit 3
chr15_+_32387063 1.38 ENSDART00000154210
ENSDART00000156525
si:ch211-162k9.5
chr12_+_17154655 1.36 ENSDART00000028003
ankyrin repeat domain 22
chr22_+_38276024 1.35 ENSDART00000143792
REST corepressor 3
chr22_+_35205546 1.35 ENSDART00000189203
TSC22 domain family 2
chr19_-_23249822 1.34 ENSDART00000140665
growth factor receptor-bound protein 10a
chr16_+_39146696 1.34 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr6_-_8360918 1.32 ENSDART00000004716
acid phosphatase 5a, tartrate resistant
chr10_+_6884123 1.32 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr20_-_32981053 1.32 ENSDART00000138708
neuroblastoma amplified sequence
chr15_+_23657051 1.29 ENSDART00000078336
kinesin light chain 3
chr12_-_33558727 1.27 ENSDART00000086087
mbt domain containing 1
chr19_-_25081711 1.26 ENSDART00000058513
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3
chr23_-_29878643 1.26 ENSDART00000058407
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr19_+_43669122 1.26 ENSDART00000139151
si:ch211-193k19.1
chr19_+_33850705 1.25 ENSDART00000160356
peroxisomal biogenesis factor 1
chr7_+_13582256 1.25 ENSDART00000158477
ankyrin repeat and death domain containing 1A
chr5_+_37504309 1.25 ENSDART00000165465
si:ch1073-224n8.1
chr23_+_19594608 1.24 ENSDART00000134865
sarcolemma associated protein b
chr12_-_33558879 1.22 ENSDART00000161167
mbt domain containing 1
chr3_+_31087509 1.21 ENSDART00000129564
si:dkey-66i24.8
chr25_+_19913611 1.21 ENSDART00000155029
GRAM domain containing 4b
chr8_-_35960987 1.20 ENSDART00000160503
solute carrier family 15 (oligopeptide transporter), member 4
chr6_+_6822592 1.19 ENSDART00000151057
si:ch211-85n16.4
chr5_+_27267186 1.18 ENSDART00000182238
ENSDART00000087857
unc-5 netrin receptor Db
chr25_-_13871118 1.17 ENSDART00000160866
cryptochrome circadian clock 2
chr4_-_26095755 1.17 ENSDART00000100611
ENSDART00000191266
si:ch211-244b2.3
chr6_+_49771372 1.16 ENSDART00000063251
cathepsin Z
chr7_-_19997095 1.16 ENSDART00000180955
thyroid hormone receptor interactor 6
chr19_+_24068223 1.16 ENSDART00000141351
ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr13_+_42309688 1.15 ENSDART00000158367
insulin-degrading enzyme
chr1_-_59243542 1.15 ENSDART00000163021
multivesicular body subunit 12A
chr4_-_12286067 1.15 ENSDART00000022646
CCR4-NOT transcription complex, subunit 4b
chr21_+_19334198 1.15 ENSDART00000147372
helicase, POLQ like
chr6_+_49771626 1.14 ENSDART00000134207
cathepsin Z
chr17_+_28005763 1.14 ENSDART00000155838
leucine zipper protein 1
chr6_+_11760749 1.14 ENSDART00000112212
zinc finger, SWIM-type containing 2
chr9_+_21977383 1.12 ENSDART00000135032
si:dkey-57a22.11
chr23_-_37291793 1.12 ENSDART00000083281
ENSDART00000187108
mitochondrial E3 ubiquitin protein ligase 1b
chr3_-_48612078 1.10 ENSDART00000169923
nudE neurodevelopment protein 1-like 1b
chr23_+_9508538 1.10 ENSDART00000010697
oxysterol binding protein-like 2b
chr7_+_39011852 1.09 ENSDART00000093009
diacylglycerol kinase, zeta a
chr13_-_34862452 1.09 ENSDART00000134573
ENSDART00000047552
serine palmitoyltransferase, long chain base subunit 3
chr15_-_14194208 1.09 ENSDART00000188237
ENSDART00000183155
ENSDART00000165520
polynucleotide kinase 3'-phosphatase
chr4_-_14649158 1.09 ENSDART00000145737
si:dkey-183c2.4
chr3_+_35005730 1.09 ENSDART00000029451
protein kinase C, beta b
chr9_-_12574473 1.06 ENSDART00000191372
ENSDART00000193667
insulin-like growth factor 2 mRNA binding protein 2a
chr9_-_25443094 1.05 ENSDART00000105492
activin A receptor type 2Aa
chr8_-_12432604 1.05 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
TNF receptor-associated factor 1
chr16_+_52343905 1.05 ENSDART00000131051
interferon lambda receptor 1
chr5_+_57480014 1.04 ENSDART00000135520
si:ch211-202f5.3
chr3_-_40254634 1.04 ENSDART00000154562
DNA topoisomerase III alpha
chr17_-_24938845 1.04 ENSDART00000156953

chr16_+_38337783 1.04 ENSDART00000135008
GA binding protein transcription factor, beta subunit 2b
chr4_+_55758103 1.03 ENSDART00000185964

chr15_-_14193926 1.03 ENSDART00000162707
polynucleotide kinase 3'-phosphatase
chr20_+_51006362 1.03 ENSDART00000028084
membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5)
chr10_+_37181780 1.03 ENSDART00000187625
kinase suppressor of ras 1a
chr20_-_42241150 1.02 ENSDART00000142791
NUS1 dehydrodolichyl diphosphate synthase subunit
chr19_-_8940068 1.01 ENSDART00000043507
circadian associated repressor of transcription a
chr10_+_2975974 1.01 ENSDART00000147918
zinc finger, FYVE domain containing 16
chr17_+_44441042 1.01 ENSDART00000142123
adaptor-related protein complex 5, mu 1 subunit
chr13_+_35856463 1.00 ENSDART00000171056
ENSDART00000017202
potassium channel, subfamily K, member 1b
chr22_+_35275468 1.00 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr2_-_37458527 0.99 ENSDART00000146820
si:dkey-57k2.7
chr22_-_9860792 0.99 ENSDART00000155908
si:dkey-253d23.2
chr19_+_7424347 0.99 ENSDART00000004622
splicing factor 3b, subunit 4
chr23_+_33934228 0.99 ENSDART00000134237
si:ch211-148l7.4
chr11_-_26832685 0.98 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr19_+_42227400 0.98 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr5_-_12031174 0.98 ENSDART00000159896
cytosolic arginine sensor for mTORC1 subunit 1
chr22_-_19102256 0.97 ENSDART00000171866
ENSDART00000166295
polymerase (RNA) mitochondrial (DNA directed)
chr18_-_42313798 0.96 ENSDART00000098639
contactin 5
chr12_+_34854562 0.96 ENSDART00000130366
si:dkey-21c1.4
chr2_+_52065884 0.96 ENSDART00000146418
Src homology 2 domain containing transforming protein D, a
chr22_+_35275206 0.95 ENSDART00000112234
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr8_+_23861461 0.95 ENSDART00000037109
SRSF protein kinase 1a
chr14_-_33978117 0.95 ENSDART00000128515
forkhead box A sequence
chr20_+_2134816 0.94 ENSDART00000039249
l(3)mbt-like 3 (Drosophila)
chr15_+_17722054 0.93 ENSDART00000191390
ENSDART00000169550
si:ch211-213d14.1
chr19_+_20201254 0.93 ENSDART00000010140
insulin-like growth factor 2 mRNA binding protein 3
chr23_+_24501918 0.91 ENSDART00000078824
SUZ RNA binding domain containing 1
chr16_-_12060770 0.91 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
chr11_+_31323746 0.90 ENSDART00000180220
ENSDART00000189937
signal-induced proliferation-associated 1 like 2
chr9_-_16239032 0.89 ENSDART00000131398
ENSDART00000138204
myosin IB
chr3_-_31086770 0.89 ENSDART00000103421
zgc:153292
chr9_+_13638329 0.89 ENSDART00000143432
amyotrophic lateral sclerosis 2a (juvenile)
chr23_+_4226341 0.88 ENSDART00000012445
zgc:113278
chr5_+_4006837 0.87 ENSDART00000138862
phosphatidylinositol glycan anchor biosynthesis, class W
chr4_+_77966055 0.87 ENSDART00000174203
ENSDART00000130100
ENSDART00000080665
ENSDART00000174317
ENSDART00000190123
zgc:113921
chr7_+_13491452 0.87 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr22_-_7700179 0.86 ENSDART00000145047
si:ch211-59h6.1
chr18_-_35459605 0.85 ENSDART00000135691
inositol-trisphosphate 3-kinase Cb
chr10_-_32494304 0.85 ENSDART00000028161
UV radiation resistance associated gene
chr21_+_11865972 0.84 ENSDART00000081676
ubiquitin associated protein 1
chr25_-_20049449 0.84 ENSDART00000104315
zgc:136858
chr12_-_31422433 0.84 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vesicle transport through interaction with t-SNAREs 1A
chr20_-_42241456 0.82 ENSDART00000034054
NUS1 dehydrodolichyl diphosphate synthase subunit
chr24_+_23730061 0.82 ENSDART00000080343
protein phosphatase 1, regulatory subunit 42
chr9_-_43207768 0.81 ENSDART00000192523
SEC14 and spectrin domains 1
chr7_+_30051880 0.81 ENSDART00000075609
proline-serine-threonine phosphatase interacting protein 1b
chr5_-_69621227 0.80 ENSDART00000178543
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr14_+_8940326 0.80 ENSDART00000159920
ribosomal protein S6 kinase a, like
chr16_-_12060488 0.80 ENSDART00000188733
si:ch211-69g19.2
chr24_-_25166416 0.80 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr8_+_7097929 0.80 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
ankyrin repeat and BTB (POZ) domain containing 1
chr9_-_29003245 0.78 ENSDART00000183391
ENSDART00000188836
protein tyrosine phosphatase, non-receptor type 4a
chr10_+_6907715 0.78 ENSDART00000041068
solute carrier family 38, member 9
chr19_+_38168006 0.78 ENSDART00000087662
ENSDART00000177759
PHD finger protein 14
chr1_-_1894722 0.77 ENSDART00000165669
si:ch211-132g1.3
chr11_-_18557929 0.75 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
death inducer-obliterator 1
chr3_+_35005062 0.74 ENSDART00000181163
protein kinase C, beta b
chr1_-_53918839 0.74 ENSDART00000032552
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr21_+_37513058 0.74 ENSDART00000141096
angiomotin
chr3_+_46764278 0.74 ENSDART00000136051
ENSDART00000164930
protein kinase C substrate 80K-H
chr10_-_31015535 0.73 ENSDART00000146116
pannexin 3
chr16_-_36746837 0.73 ENSDART00000189276
ENSDART00000085228
phosphoinositide-3-kinase, regulatory subunit 4
chr7_+_5905091 0.72 ENSDART00000167099
Histone H3.2
chr17_-_44440832 0.72 ENSDART00000148786
exocyst complex component 5
chr19_+_38167468 0.72 ENSDART00000160756
PHD finger protein 14
chr5_-_23473312 0.72 ENSDART00000140310
si:dkeyp-20g2.3
chr1_+_55095314 0.72 ENSDART00000132727
aftiphilin a
chr21_+_37513488 0.71 ENSDART00000185394
angiomotin
chr22_+_12361317 0.71 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr20_+_14789305 0.71 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr12_-_33706726 0.70 ENSDART00000153135
myosin XVB
chr18_+_2228737 0.69 ENSDART00000165301
RAB27A, member RAS oncogene family
chr22_-_5099824 0.69 ENSDART00000122341
ENSDART00000161345
zinc finger RNA binding protein 2
chr24_+_17334682 0.69 ENSDART00000018868
protein disulfide isomerase family A, member 4
chr11_+_19271557 0.69 ENSDART00000190559
prickle homolog 2b
chr4_-_4535189 0.68 ENSDART00000057519
zgc:194209
chr3_-_27065477 0.67 ENSDART00000185660
activating transcription factor 7 interacting protein 2
chr25_-_25142387 0.67 ENSDART00000031814
tumor susceptibility 101a
chr23_-_4225830 0.67 ENSDART00000170455
AAR2 splicing factor homolog (S. cerevisiae)
chr8_-_28339151 0.67 ENSDART00000148765
ENSDART00000149173
ENSDART00000150113
lysine (K)-specific demethylase 5Bb
chr20_-_154989 0.66 ENSDART00000064542
ribosome production factor 2 homolog
chr17_+_13099476 0.66 ENSDART00000012670
pinin, desmosome associated protein
chr14_-_21932403 0.65 ENSDART00000054420
RAD9 checkpoint clamp component A
chr3_+_31058464 0.65 ENSDART00000153381
si:dkey-66i24.7
chr25_-_3058687 0.65 ENSDART00000149117
ENSDART00000137950
si:ch1073-296i8.2
chr11_-_42417194 0.64 ENSDART00000191086
ENSDART00000076650
ENSDART00000165903
ENSDART00000104444
sarcolemma associated protein a
chr2_-_41571454 0.64 ENSDART00000022643
zinc finger protein 622
chr19_+_20201593 0.61 ENSDART00000163026
insulin-like growth factor 2 mRNA binding protein 3
chr11_+_6431133 0.60 ENSDART00000190742

chr9_+_23770666 0.60 ENSDART00000182493
si:ch211-219a4.3
chr5_-_67365750 0.60 ENSDART00000062359
uracil DNA glycosylase a
chr6_-_19664848 0.60 ENSDART00000159749
ubiquitin specific peptidase 43a
chr5_-_67365006 0.59 ENSDART00000136116
uracil DNA glycosylase a
chr11_-_2478374 0.59 ENSDART00000173205
si:ch73-267c23.10
chr10_-_625441 0.59 ENSDART00000171171
regulatory factor X, 3 (influences HLA class II expression)
chr5_+_51111766 0.59 ENSDART00000188552
protein-O-mannosyltransferase 1
chr25_+_28693451 0.59 ENSDART00000148366
CCR4-NOT transcription complex, subunit 2
chr21_+_11749097 0.58 ENSDART00000102408
ENSDART00000102404
elongation factor, RNA polymerase II, 2
chr2_-_13254594 0.58 ENSDART00000155671
3-ketodihydrosphingosine reductase
chr18_+_8812549 0.58 ENSDART00000017619
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr23_+_31596441 0.57 ENSDART00000053534
TBP-like 1
chr20_+_38837238 0.57 ENSDART00000061334
intraflagellar transport 172

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc13b+hoxd13a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0005991 trehalose metabolic process(GO:0005991)
1.3 6.3 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.7 3.4 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.6 1.9 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.6 1.8 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.6 2.8 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.5 2.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.5 1.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.4 1.3 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.4 1.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 1.3 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.0 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 1.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 1.2 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.3 2.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3 1.3 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.2 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.9 GO:0060074 synapse maturation(GO:0060074)
0.2 3.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.2 1.2 GO:0016559 peroxisome fission(GO:0016559)
0.2 1.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.5 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 1.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 0.8 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.4 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 1.2 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 0.6 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 1.2 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 1.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 1.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.3 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.7 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 2.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.4 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.9 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 2.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:1902914 regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 1.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 1.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.5 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.1 0.7 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 3.4 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 1.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 1.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.6 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 2.1 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 1.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 2.3 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0045453 bone resorption(GO:0045453)
0.0 1.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0090398 cellular senescence(GO:0090398)
0.0 1.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 2.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.8 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 2.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0035264 multicellular organism growth(GO:0035264)
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.7 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.6 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.0 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.2 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.6 GO:0016197 endosomal transport(GO:0016197)
0.0 2.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.8 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.7 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 1.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.3 GO:0006413 translational initiation(GO:0006413)
0.0 1.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.4 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.3 0.8 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.9 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.7 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.7 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 3.6 GO:0043186 P granule(GO:0043186)
0.1 1.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.7 GO:0030914 STAGA complex(GO:0030914)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0071439 clathrin complex(GO:0071439)
0.1 1.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.9 GO:0005903 brush border(GO:0005903)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 1.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.6 GO:0005814 centriole(GO:0005814)
0.0 2.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.0 2.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 4.3 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.0 GO:0043204 perikaryon(GO:0043204)
0.0 1.2 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0000776 kinetochore(GO:0000776)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.7 2.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.6 2.6 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.5 1.8 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.4 1.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4 1.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 2.0 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.3 1.0 GO:0034618 arginine binding(GO:0034618)
0.3 1.8 GO:0035173 histone kinase activity(GO:0035173)
0.2 0.7 GO:0043621 protein self-association(GO:0043621)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 1.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 1.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 3.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.7 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 1.3 GO:0019894 kinesin binding(GO:0019894)
0.1 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 2.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.2 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 3.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 3.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.9 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 5.4 GO:0005125 cytokine activity(GO:0005125)
0.0 1.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.5 GO:0046332 SMAD binding(GO:0046332)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 1.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 7.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 1.3 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.3 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.7 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 1.7 GO:0015293 symporter activity(GO:0015293)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.7 PID ATM PATHWAY ATM pathway
0.0 1.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 4.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.7 3.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.3 REACTOME KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.5 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.7 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress