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PRJNA195909:zebrafish embryo and larva development

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Results for hoxc11b

Z-value: 1.11

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Transcription factors associated with hoxc11b

Gene Symbol Gene ID Gene Info
ENSDARG00000102631 homeobox C11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc11bdr11_v1_chr11_+_2180072_21800720.732.7e-02Click!

Activity profile of hoxc11b motif

Sorted Z-values of hoxc11b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_27027781 3.44 ENSDART00000065495
epithelial membrane protein 2
chr22_-_4644484 3.24 ENSDART00000167748
fibrillin 2b
chr23_+_39606108 3.17 ENSDART00000109464
G0/G1 switch 2
chr16_-_45917322 2.99 ENSDART00000060822
antifreeze protein type IV
chr14_-_25949951 2.35 ENSDART00000141304
secreted protein, acidic, cysteine-rich (osteonectin)
chr8_+_47633438 2.33 ENSDART00000139096
si:ch211-251b21.1
chr6_+_35362225 2.15 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr5_+_70155935 2.04 ENSDART00000165570
regulator of G protein signaling 3a
chr1_+_46194333 2.03 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr20_-_26491567 1.90 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr16_-_55028740 1.88 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr24_+_5237753 1.84 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr18_+_26422124 1.83 ENSDART00000060245
cathepsin H
chr11_+_30244356 1.82 ENSDART00000036050
ENSDART00000150080
retinoschisin 1a
chr25_+_20089986 1.79 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr2_+_20406399 1.78 ENSDART00000006817
ENSDART00000137848
palmdelphin a
chr23_+_10146542 1.70 ENSDART00000048073
zgc:171775
chr17_+_52822831 1.67 ENSDART00000193368
Meis homeobox 2a
chr22_-_14115292 1.66 ENSDART00000105717
ENSDART00000165670
aldehyde oxidase 5
chr25_+_29161609 1.66 ENSDART00000180752
pyruvate kinase M1/2b
chr8_+_39619087 1.63 ENSDART00000134822
musashi RNA-binding protein 1
chr1_+_44439661 1.62 ENSDART00000100309
crystallin, beta B1, like 2
chr18_-_15373620 1.61 ENSDART00000031752
regulatory factor X, 4
chr23_+_36052944 1.60 ENSDART00000103149
homeobox C13a
chr12_+_27117609 1.57 ENSDART00000076154
homeobox B8b
chr2_+_2223837 1.57 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr8_-_44298964 1.56 ENSDART00000098520
frizzled class receptor 10
chr5_-_65037525 1.56 ENSDART00000158856
annexin A1b
chr19_-_14191592 1.54 ENSDART00000164594
T-box transcription factor Ta
chr20_+_52546186 1.47 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr2_-_59145027 1.47 ENSDART00000128320

chr23_+_25354856 1.45 ENSDART00000109023
ENSDART00000147440
formin-like 3
chr6_-_60147517 1.44 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr10_-_22803740 1.41 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr23_+_27068225 1.38 ENSDART00000054238
major intrinsic protein of lens fiber a
chr19_+_19762183 1.36 ENSDART00000163611
ENSDART00000187604
homeobox A3a
chr11_+_25257022 1.35 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr5_-_40510397 1.34 ENSDART00000146237
ENSDART00000051065
follistatin a
chr5_-_41307550 1.32 ENSDART00000143446
natriuretic peptide receptor 3
chr9_-_48370645 1.32 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr25_-_13614863 1.31 ENSDART00000121859
fatty acid 2-hydroxylase
chr12_-_20373058 1.31 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr9_+_17306162 1.29 ENSDART00000075926
sciellin
chr19_+_19747430 1.24 ENSDART00000166129
homeobox A9a
chr2_+_52847049 1.24 ENSDART00000121980
cAMP responsive element binding protein 3-like 3b
chr10_+_36650222 1.23 ENSDART00000126963
uncoupling protein 3
chr8_-_38159805 1.22 ENSDART00000112331
ENSDART00000180006
adhesion G protein-coupled receptor A2
chr5_-_42272517 1.22 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr24_-_8732519 1.21 ENSDART00000082351
transcription factor AP-2 alpha
chr10_-_29903165 1.20 ENSDART00000078800
lens intrinsic membrane protein 2.1
chr7_+_34290051 1.19 ENSDART00000123498
fin bud initiation factor b
chr19_-_35733401 1.17 ENSDART00000066712
trafficking protein particle complex 3
chr20_+_26880668 1.16 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr21_+_25236297 1.14 ENSDART00000112783
transmembrane protein 45B
chr3_+_62161184 1.11 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr17_+_52822422 1.11 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr18_+_22606259 1.11 ENSDART00000128965
breast cancer anti-estrogen resistance 1
chr24_-_17029374 1.10 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr7_+_36041509 1.08 ENSDART00000162850
iroquois homeobox 3a
chr9_-_1949915 1.07 ENSDART00000190712
homeobox D3a
chr13_+_4405282 1.03 ENSDART00000148280
proline rich 18
chr4_+_5741733 1.03 ENSDART00000110243
POU class 3 homeobox 2a
chr3_+_23710839 1.02 ENSDART00000151584
homeobox B4a
chr2_-_40135942 0.98 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr21_-_20341836 0.97 ENSDART00000176689
retinol binding protein 4, like
chr23_+_7379728 0.97 ENSDART00000012194
GATA binding protein 5
chr7_+_46003449 0.96 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
chr17_+_52823015 0.96 ENSDART00000160507
ENSDART00000186979
Meis homeobox 2a
chr10_-_10864331 0.93 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr16_+_21242491 0.92 ENSDART00000145886
oxysterol binding protein-like 3b
chr23_+_36122058 0.91 ENSDART00000184448
homeobox C3a
chr10_-_31562695 0.90 ENSDART00000186456
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr24_-_6158933 0.89 ENSDART00000021609
glutamate decarboxylase 2
chr1_-_44933094 0.89 ENSDART00000147527
si:dkey-9i23.14
chr7_-_58952382 0.88 ENSDART00000167076
mannose receptor, C type 1a
chr5_-_48307804 0.88 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
myocyte enhancer factor 2cb
chr11_+_42556395 0.86 ENSDART00000039206
ribosomal protein S23
chr19_+_19761966 0.85 ENSDART00000163697
homeobox A3a
chr19_-_617246 0.83 ENSDART00000062551
cytochrome P450, family 51
chr12_+_8168272 0.83 ENSDART00000054092
AT-rich interaction domain 5B
chr10_+_2587234 0.81 ENSDART00000126937
wu:fb59d01
chr15_-_34567370 0.81 ENSDART00000099793
sclerostin domain containing 1a
chr24_+_39105051 0.79 ENSDART00000115297
MSS51 mitochondrial translational activator
chr4_-_5652030 0.78 ENSDART00000010903
radial spoke head 9 homolog
chr14_-_1958994 0.77 ENSDART00000161783
protocadherin 2 gamma 5
chr20_-_4883673 0.77 ENSDART00000145540
ENSDART00000053877
zinc finger, DHHC-type containing 14
chr3_+_24134418 0.76 ENSDART00000156204
si:ch211-246i5.5
chr13_+_28417297 0.76 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr9_+_34425736 0.75 ENSDART00000135147
si:ch211-218d20.15
chr1_-_35924495 0.75 ENSDART00000184424
SMAD family member 1
chr19_-_26736336 0.74 ENSDART00000109258
ENSDART00000182802
casein kinase 2, beta polypeptide
chr13_+_844150 0.73 ENSDART00000058260
glutathione S-transferase, alpha tandem duplicate 1
chr11_-_18253111 0.73 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr10_-_24371312 0.71 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr21_+_45819662 0.70 ENSDART00000193362
ENSDART00000184255
paired-like homeodomain 1
chr8_-_25338709 0.69 ENSDART00000131616
ATP synthase peripheral stalk-membrane subunit b
chr4_+_37406676 0.69 ENSDART00000130981
si:ch73-134f24.1
chr4_-_56898328 0.67 ENSDART00000169189
si:dkey-269o24.6
chr20_+_40237441 0.67 ENSDART00000168928
si:ch211-199i15.5
chr5_+_24245682 0.66 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr10_+_22775253 0.66 ENSDART00000190141
transmembrane protein 88 a
chr2_-_30659222 0.66 ENSDART00000145405
catenin (cadherin-associated protein), delta 2b
chr5_-_9073433 0.65 ENSDART00000099891
ATP synthase membrane subunit eb
chr19_+_4916233 0.64 ENSDART00000159512
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_+_39386982 0.63 ENSDART00000146702
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr23_+_18722715 0.61 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr10_-_31563049 0.60 ENSDART00000023575
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr3_-_19200571 0.59 ENSDART00000131503
ENSDART00000012335
regulatory factor X, 1a (influences HLA class II expression)
chr3_+_25154078 0.59 ENSDART00000156973
si:ch211-256m1.8
chr7_+_30875273 0.59 ENSDART00000173693
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr9_-_23156908 0.58 ENSDART00000135461
LY6/PLAUR domain containing 6B
chr1_-_22512063 0.58 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr6_-_57938043 0.57 ENSDART00000171073
TOX high mobility group box family member 2
chr21_-_17296789 0.56 ENSDART00000192180
growth factor independent 1B transcription repressor
chr19_+_1370504 0.56 ENSDART00000158946
diacylglycerol O-acyltransferase 1a
chr7_-_23745984 0.56 ENSDART00000048050
zgc:92429
chr23_-_12014931 0.56 ENSDART00000134652
si:dkey-178k16.1
chr2_-_44283554 0.55 ENSDART00000184684
myelin protein zero
chr3_-_58798377 0.55 ENSDART00000161248
si:ch73-281f12.4
chr19_+_16032383 0.55 ENSDART00000046530
RAB42, member RAS oncogene family a
chr16_+_54829293 0.54 ENSDART00000024729
poly(A) binding protein, cytoplasmic 1a
chr19_-_10243148 0.54 ENSDART00000148073
shisa family member 7
chr1_+_961607 0.54 ENSDART00000184660
N-6 adenine-specific DNA methyltransferase 1
chr10_+_16069987 0.53 ENSDART00000043936
multiple EGF-like-domains 10
chr14_+_22447662 0.53 ENSDART00000161776
sosondowah ankyrin repeat domain family member Ab
chr7_-_16562200 0.52 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr15_-_25527580 0.52 ENSDART00000167005
ENSDART00000157498
hypoxia-inducible factor 1, alpha subunit, like
chr9_-_41784799 0.52 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obscurin-like 1b
chr7_-_29534001 0.51 ENSDART00000124028
annexin A2b
chr19_+_42469058 0.51 ENSDART00000076915
si:dkey-166k12.1
chr17_-_43666166 0.51 ENSDART00000077990
early growth response 2a
chr10_+_506538 0.50 ENSDART00000141713
si:ch211-242f23.3
chr1_+_47486104 0.49 ENSDART00000114746
leucine rich repeat containing 58a
chr14_+_30279391 0.49 ENSDART00000172794
fibrinogen-like 1
chr4_+_27130412 0.49 ENSDART00000145083
bromodomain containing 1a
chr11_-_12998400 0.48 ENSDART00000018614
cholinergic receptor, nicotinic, alpha 4b
chr14_+_30795559 0.48 ENSDART00000006132
cofilin 1
chr6_-_6448519 0.48 ENSDART00000180157
ENSDART00000191112
si:ch211-194e18.2
chr23_-_3758637 0.48 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr2_-_59178742 0.47 ENSDART00000170594
ENSDART00000109246
finTRIM family, member 95
chr17_-_18888959 0.47 ENSDART00000080029
adenylate kinase 7b
chr13_+_36585399 0.46 ENSDART00000030211
glia maturation factor, beta
chr17_+_27456804 0.46 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr7_-_26457208 0.45 ENSDART00000173519
zgc:172079
chr21_+_11401247 0.45 ENSDART00000143952
carboxyl ester lipase, tandem duplicate 1
chr4_-_149334 0.44 ENSDART00000163280
TANK-binding kinase 1
chr14_+_49135264 0.44 ENSDART00000084119
si:ch1073-44g3.1
chr9_+_917060 0.44 ENSDART00000082390
transmembrane protein 37
chr11_-_29737088 0.43 ENSDART00000159828
si:ch211-218g23.6
chr20_+_33532296 0.43 ENSDART00000153153
potassium voltage-gated channel, subfamily F, member 1a
chr2_+_49417900 0.43 ENSDART00000122742
ENSDART00000160783
RAR-related orphan receptor C b
chr2_+_5927255 0.43 ENSDART00000152866
si:ch211-168b3.2
chr11_+_21053488 0.42 ENSDART00000189860
zgc:113307
chr25_-_13614702 0.42 ENSDART00000165510
ENSDART00000190959
fatty acid 2-hydroxylase
chr11_-_38928760 0.42 ENSDART00000146277
si:ch211-122l14.6
chr10_+_15064433 0.41 ENSDART00000179978
prostate androgen-regulated mucin-like protein 1
chr23_+_36074798 0.40 ENSDART00000133760
ENSDART00000103146
homeobox C11a
chr6_-_50704689 0.40 ENSDART00000074100
oxidative stress induced growth inhibitor 1
chr11_-_6265574 0.40 ENSDART00000181974
ENSDART00000104405
chemokine (C-C motif) ligand 25b
chr21_+_9689103 0.40 ENSDART00000165132
mitogen-activated protein kinase 10
chr6_+_54221654 0.40 ENSDART00000128456
protein kinase C and casein kinase substrate in neurons 1b
chr10_-_3332362 0.40 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr23_+_18722915 0.39 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr25_-_26758253 0.38 ENSDART00000123004
si:dkeyp-73b11.8
chr22_+_19111444 0.38 ENSDART00000109655
fibroblast growth factor 22
chr10_-_6427362 0.38 ENSDART00000166774
carbonic anhydrase IX
chr13_-_11986754 0.37 ENSDART00000164214
nucleophosmin/nucleoplasmin, 3
chr16_-_43679611 0.36 ENSDART00000123585

chr8_+_52637507 0.36 ENSDART00000163830
si:dkey-90l8.3
chr22_+_25331766 0.36 ENSDART00000155006
ENSDART00000155836
si:ch211-226h8.15
chr10_-_25591194 0.36 ENSDART00000131640
T cell lymphoma invasion and metastasis 1a
chr16_+_13883872 0.35 ENSDART00000101304
ENSDART00000136005
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr24_+_5840258 0.35 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr17_-_12389259 0.35 ENSDART00000185724
synaptosomal-associated protein, 25b
chr7_+_39634873 0.35 ENSDART00000114774
protein tyrosine phosphatase, non-receptor type 5
chr20_-_14462995 0.34 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr12_+_19356623 0.34 ENSDART00000078284
DNA meiotic recombinase 1
chr19_-_32600823 0.34 ENSDART00000134149
ENSDART00000187858
zgc:91944
chr7_+_18075504 0.33 ENSDART00000173689
si:ch73-40a2.1
chr7_+_11543999 0.33 ENSDART00000173676
interleukin 16
chr24_-_1356668 0.32 ENSDART00000188935
neuropilin 1a
chr4_-_71177920 0.32 ENSDART00000158287
si:dkey-193i10.1
chr8_+_30709685 0.32 ENSDART00000133989
ureidopropionase, beta
chr5_-_67750907 0.32 ENSDART00000172097
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr4_-_73136420 0.32 ENSDART00000160907
si:ch73-170d6.3
chr11_+_25112269 0.32 ENSDART00000147546
ndrg family member 3a
chr4_+_43522945 0.31 ENSDART00000183921
ENSDART00000181832
si:dkeyp-53e4.4
chr6_+_30703828 0.31 ENSDART00000104628
insulin-like 5a
chr11_+_36665359 0.31 ENSDART00000166144
si:ch211-11c3.9
chr14_-_2221877 0.31 ENSDART00000106704
protocadherin 2 alpha b 1
chr15_+_14856307 0.31 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr21_+_10756154 0.30 ENSDART00000074833
retinal homeobox gene 3
chr6_+_13083146 0.30 ENSDART00000172158
trans-L-3-hydroxyproline dehydratase
chr2_+_19578446 0.30 ENSDART00000164758
Pim proto-oncogene, serine/threonine kinase, related 50
chr18_-_15559817 0.29 ENSDART00000061681
si:ch211-245j22.3
chr3_+_24190207 0.29 ENSDART00000034762
proline rich 15-like a
chr20_-_48701593 0.29 ENSDART00000132835
paired box 1b
chr21_+_21906671 0.29 ENSDART00000016916
glutamate receptor, ionotropic, AMPA 4b
chr9_+_32860345 0.29 ENSDART00000121751
si:dkey-145p14.5
chr2_+_36862473 0.28 ENSDART00000135624
si:dkey-193b15.8

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
1.1 3.4 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.5 1.8 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.4 2.0 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 1.2 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.4 1.5 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.3 2.2 GO:0060017 parathyroid gland development(GO:0060017)
0.3 0.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 1.6 GO:0033028 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 1.0 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.7 GO:0061317 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.2 1.6 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.2 1.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.6 GO:0006833 water transport(GO:0006833)
0.2 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.0 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 3.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.4 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 0.5 GO:0035994 response to muscle stretch(GO:0035994)
0.1 3.0 GO:0060030 dorsal convergence(GO:0060030)
0.1 1.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 1.5 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.1 1.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.5 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.9 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.3 GO:0042148 strand invasion(GO:0042148)
0.1 1.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 1.2 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 0.3 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.2 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.3 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.2 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.5 GO:0035094 response to nicotine(GO:0035094)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 1.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 3.2 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 1.6 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 3.0 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 1.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.8 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.9 GO:0060914 heart formation(GO:0060914)
0.0 0.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0050926 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 1.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096)
0.0 1.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.5 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 1.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.6 GO:0031101 fin regeneration(GO:0031101)
0.0 0.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.5 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 3.0 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.3 GO:0008544 epidermis development(GO:0008544)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.3 1.2 GO:1990909 Wnt signalosome(GO:1990909)
0.3 0.8 GO:0001534 radial spoke(GO:0001534)
0.2 1.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.7 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 3.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.6 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.6 2.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 1.7 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.6 1.7 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 1.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 2.7 GO:0015250 water channel activity(GO:0015250)
0.3 0.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 1.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 1.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.0 GO:0034632 retinol transporter activity(GO:0034632)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0000150 recombinase activity(GO:0000150)
0.1 1.4 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.5 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 2.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 3.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0051020 GTPase binding(GO:0051020)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 17.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 3.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 2.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 3.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs