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PRJNA195909:zebrafish embryo and larva development

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Results for hoxb8a+hoxb8b

Z-value: 1.41

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Transcription factors associated with hoxb8a+hoxb8b

Gene Symbol Gene ID Gene Info
ENSDARG00000054025 homeobox B8b
ENSDARG00000056027 homeobox B8a
ENSDARG00000111056 homeobox B8b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb8bdr11_v1_chr12_+_27117609_271176090.472.1e-01Click!
hoxb8adr11_v1_chr3_+_23687909_236879090.452.2e-01Click!

Activity profile of hoxb8a+hoxb8b motif

Sorted Z-values of hoxb8a+hoxb8b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38301080 3.48 ENSDART00000105672
myosin binding protein C, fast type b
chr2_+_33368414 2.09 ENSDART00000077462
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_+_33300522 1.88 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr10_-_39011514 1.82 ENSDART00000075123
Purkinje cell protein 4a
chr1_+_17676745 1.68 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr12_-_26406323 1.56 ENSDART00000131896
myozenin 1b
chr6_+_52804267 1.55 ENSDART00000065681
matrilin 4
chr19_-_3123963 1.48 ENSDART00000122816
si:ch211-80h18.1
chr4_-_4387012 1.28 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr7_+_31879649 1.19 ENSDART00000099789
myosin binding protein C, cardiac
chr13_+_23282549 1.18 ENSDART00000101134
KH domain containing, RNA binding, signal transduction associated 2
chr1_+_16144615 1.17 ENSDART00000054707
tumor suppressor candidate 3
chr18_-_38088099 1.15 ENSDART00000146120
leucine zipper protein 2
chr15_+_4632782 1.13 ENSDART00000156012
si:dkey-35i13.1
chr18_+_21408794 1.03 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr6_-_43449013 1.03 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr7_+_31879986 1.03 ENSDART00000138491
myosin binding protein C, cardiac
chr9_+_42066030 1.01 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr23_-_11870962 1.01 ENSDART00000143481
si:dkey-178k16.1
chr20_+_20672163 1.00 ENSDART00000027758
reticulon 1b
chr3_+_23752150 0.98 ENSDART00000146636
homeobox B2a
chr25_+_15647750 0.98 ENSDART00000137375
spondin 1b
chr15_+_28202170 0.96 ENSDART00000077736
vitronectin a
chr2_+_2223837 0.96 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr13_-_30027730 0.93 ENSDART00000044009
stearoyl-CoA desaturase b
chr16_+_10776688 0.91 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr9_-_23217196 0.91 ENSDART00000083567
kinesin family member 5C
chr2_-_9646857 0.91 ENSDART00000056901
zgc:153615
chr14_+_25465346 0.87 ENSDART00000173436
si:dkey-280e21.3
chr12_+_39685485 0.87 ENSDART00000163403

chr10_-_7785930 0.87 ENSDART00000043961
ENSDART00000111058
myeloid-specific peroxidase
chr8_-_14484599 0.82 ENSDART00000057644
LIM homeobox 4
chr19_+_12444943 0.82 ENSDART00000135706
low density lipoprotein receptor class A domain containing 4a
chr5_-_825920 0.82 ENSDART00000126982
zgc:158463
chr13_-_5569562 0.81 ENSDART00000102576
Meis homeobox 1 b
chr6_+_14949950 0.79 ENSDART00000149202
ENSDART00000149949
POU class 3 homeobox 3b
chr24_-_28893251 0.77 ENSDART00000042065
ENSDART00000003503
collagen, type XI, alpha 1a
chr24_+_24461341 0.76 ENSDART00000147658
basic helix-loop-helix family, member e22
chr22_+_18389271 0.75 ENSDART00000088270
YjeF N-terminal domain containing 3
chr8_-_34052019 0.75 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr3_-_34337969 0.74 ENSDART00000151634
trinucleotide repeat containing 6C1
chr25_+_15647993 0.73 ENSDART00000186578
ENSDART00000031828
spondin 1b
chr24_+_24461558 0.73 ENSDART00000182424
basic helix-loop-helix family, member e22
chr4_-_9891874 0.72 ENSDART00000067193
adrenomedullin 2a
chr13_-_5568928 0.71 ENSDART00000192679
Meis homeobox 1 b
chr18_+_783936 0.67 ENSDART00000193357
ribonuclease P and MRP subunit p25, b
chr15_-_34567370 0.60 ENSDART00000099793
sclerostin domain containing 1a
chr4_+_13810811 0.59 ENSDART00000067168
PDZ domain containing ring finger 4
chr17_+_39242437 0.59 ENSDART00000156138
ENSDART00000128863
zgc:174356
chr21_-_27338639 0.59 ENSDART00000130632
hypoxia-inducible factor 1, alpha subunit, like 2
chr9_-_1951144 0.59 ENSDART00000082355
homeobox D4a
chr6_-_28980756 0.58 ENSDART00000014661
glomulin, FKBP associated protein b
chr7_-_35126374 0.57 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr2_+_7818368 0.57 ENSDART00000007068
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr8_-_34051548 0.55 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr3_+_59784632 0.55 ENSDART00000084729
platelet/endothelial cell adhesion molecule 1
chr20_-_29420713 0.55 ENSDART00000147464
ryanodine receptor 3
chr6_+_37894914 0.54 ENSDART00000148817
oculocutaneous albinism II
chr20_-_19590378 0.53 ENSDART00000152588
brain and acute leukemia, cytoplasmic b
chr1_-_19215336 0.52 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr16_+_17389116 0.50 ENSDART00000103750
ENSDART00000173448
family with sequence similarity 131, member Bb
chr12_-_17201028 0.50 ENSDART00000020541
lipase, gastric
chr24_-_26328721 0.48 ENSDART00000125468
apolipoprotein Db
chr18_+_13792490 0.48 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr17_-_30666037 0.48 ENSDART00000156509
ALK and LTK ligand 2b
chr6_-_18960105 0.48 ENSDART00000185278
ENSDART00000162968
septin 9b
chr11_+_23265157 0.46 ENSDART00000110152
colony stimulating factor 1a (macrophage)
chr8_-_52413032 0.45 ENSDART00000183039

chr12_-_11457625 0.45 ENSDART00000012318
HtrA serine peptidase 1b
chr1_-_23157583 0.44 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr21_+_43669943 0.44 ENSDART00000136025
trimethyllysine hydroxylase, epsilon
chr1_+_26071869 0.44 ENSDART00000059264
MAX dimerization protein 4
chr11_+_6819050 0.42 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr24_+_25259154 0.41 ENSDART00000171125
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr12_+_18458502 0.41 ENSDART00000108745
ring finger protein 151
chr12_-_3756405 0.41 ENSDART00000150839
family with sequence similarity 57, member Bb
chr11_-_3959889 0.40 ENSDART00000159683
polybromo 1
chr19_+_37925616 0.40 ENSDART00000148348
neurexophilin 1
chr2_+_47623202 0.40 ENSDART00000154465
si:ch211-165b10.3
chr11_+_43419809 0.39 ENSDART00000172982
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr12_+_17201522 0.37 ENSDART00000014536
ENSDART00000152452
renalase, FAD-dependent amine oxidase
chr2_+_3809226 0.37 ENSDART00000147261
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr10_+_31244619 0.35 ENSDART00000145562
ENSDART00000184412
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr14_+_36231126 0.34 ENSDART00000141766
ELOVL fatty acid elongase 6
chr5_+_9382301 0.34 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr23_-_32304650 0.33 ENSDART00000143772
ENSDART00000085642
ENSDART00000188989
diacylglycerol kinase, alpha a
chr21_-_26918901 0.33 ENSDART00000100685
leucine rich repeat and fibronectin type III domain containing 4a
chr5_+_9377005 0.33 ENSDART00000124924
UDP glucuronosyltransferase 2 family, polypeptide A7
chr10_+_26571174 0.32 ENSDART00000148617
ENSDART00000112956
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr16_-_35952789 0.32 ENSDART00000180118
eva-1 homolog Ba (C. elegans)
chr10_+_36026576 0.32 ENSDART00000193786
high mobility group box 1a
chr7_+_13382852 0.32 ENSDART00000166318
diacylglycerol lipase, alpha
chr20_+_32152355 0.31 ENSDART00000152904
ENSDART00000139507
sestrin 1
chr2_-_10188598 0.30 ENSDART00000189122
diencephalon/mesencephalon homeobox 1a
chr24_+_5840258 0.30 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr25_-_31702970 0.30 ENSDART00000153586
laminin, beta 4
chr14_+_35237613 0.30 ENSDART00000163465
early B cell factor 3a
chr1_-_46984142 0.29 ENSDART00000125032
pbx/knotted 1 homeobox 1.2
chr4_+_10754802 0.29 ENSDART00000181470
stabilin 2
chr2_-_54039293 0.29 ENSDART00000166013
abhydrolase domain containing 8a
chr20_-_2949028 0.28 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cyclin-dependent kinase 19
chr18_+_27218737 0.28 ENSDART00000111450
pleckstrin homology domain containing, family A member 7a
chr11_+_36243774 0.28 ENSDART00000023323
zgc:172270
chr1_-_8980665 0.28 ENSDART00000148182
si:ch73-191k20.3
chr12_-_38548299 0.28 ENSDART00000153374
si:dkey-1f1.3
chr11_-_3959477 0.27 ENSDART00000045971
polybromo 1
chr14_+_6954579 0.27 ENSDART00000060998
NME/NM23 family member 5
chr13_-_28272299 0.27 ENSDART00000006393
T cell leukemia homeobox 1
chr21_+_22423286 0.27 ENSDART00000133190
calcyphosine-like b
chr20_-_8443425 0.27 ENSDART00000083908
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr4_+_7391110 0.27 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr23_+_21479958 0.27 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
chr19_+_28256076 0.27 ENSDART00000133354
iroquois homeobox 4b
chr10_-_27741793 0.26 ENSDART00000129369
ENSDART00000192440
ENSDART00000189808
ENSDART00000138149
autism susceptibility candidate 2a
si:dkey-33o22.1
chr15_-_21132480 0.26 ENSDART00000078734
ENSDART00000157481
alpha-2-macroglobulin-like
chr24_+_18948665 0.26 ENSDART00000106186
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr13_+_30912385 0.26 ENSDART00000182642
dorsal root ganglia homeobox
chr5_-_201600 0.25 ENSDART00000158495

chr8_+_18588551 0.25 ENSDART00000177476
ENSDART00000063539
proline rich Gla (G-carboxyglutamic acid) 1
chr14_-_6666854 0.25 ENSDART00000133031
si:dkeyp-44a8.4
chr17_-_19626357 0.25 ENSDART00000011432
receptor accessory protein 3a
chr2_+_31665836 0.24 ENSDART00000135411
ENSDART00000143914
si:ch211-106h4.12
chr20_-_26491567 0.24 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr8_-_20380750 0.24 ENSDART00000113910
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr12_-_43428542 0.23 ENSDART00000192266
protein tyrosine phosphatase, receptor type, E, a
chr24_-_6898302 0.23 ENSDART00000158646
dipeptidyl-peptidase 6a
chr7_+_53755054 0.22 ENSDART00000181629
neogenin 1a
chr23_+_5490854 0.22 ENSDART00000175403
tubby like protein 1a
chr16_+_46401576 0.22 ENSDART00000130264
rapunzel
chr18_-_14836862 0.22 ENSDART00000124843
metastasis suppressor 1-like a
chr15_-_5467477 0.22 ENSDART00000123839
arrestin, beta 1
chr12_+_22404108 0.22 ENSDART00000153055
high density lipoprotein binding protein b
chr7_-_46777876 0.21 ENSDART00000193954
teashirt zinc finger homeobox 3b
chr18_+_34225520 0.20 ENSDART00000126115
vomeronasal 2 receptor, l1
chr24_+_13735616 0.20 ENSDART00000184267
musculin (activated B-cell factor-1)
chr5_+_19261391 0.20 ENSDART00000089173
ATPase phospholipid transporting 8B5a
chr14_+_35024521 0.20 ENSDART00000158634
ENSDART00000170631
early B cell factor 3a
chr17_-_38778826 0.20 ENSDART00000168182
ENSDART00000124041
ENSDART00000136921
D-glutamate cyclase
chr5_-_35743741 0.19 ENSDART00000046157
ENSDART00000123562
oligophrenin 1
chr10_-_33156789 0.19 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cut-like homeobox 1a
chr1_-_681116 0.19 ENSDART00000165894
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_+_20519846 0.19 ENSDART00000109680
ENSDART00000142220
V-set domain containing T cell activation inhibitor 1
chr5_+_19261687 0.18 ENSDART00000139401
ATPase phospholipid transporting 8B5a
chr7_-_33248773 0.18 ENSDART00000052389
integrin, alpha 11a
chr7_-_18598661 0.18 ENSDART00000182109
si:ch211-119e14.2
chr1_-_21901589 0.17 ENSDART00000140553
FERM and PDZ domain containing 1a
chr6_+_23931236 0.16 ENSDART00000166079
growth arrest and DNA-damage-inducible, alpha, b
chr9_+_38075851 0.15 ENSDART00000135314
calcium channel, voltage-dependent, beta 4a subunit
chr15_-_21155641 0.15 ENSDART00000061098
ENSDART00000046443
si:dkey-105h12.2
chr24_+_41915878 0.14 ENSDART00000171523
transmembrane protein 200C
chr1_+_23784905 0.14 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit homolog 2 (Drosophila)
chr14_+_46274611 0.13 ENSDART00000134363
calcium binding protein 2b
chr1_+_57151926 0.13 ENSDART00000152628
si:ch73-94k4.5
chr13_-_8776474 0.13 ENSDART00000122371
si:ch211-93n23.7
chr11_-_2838699 0.12 ENSDART00000066189
LHFPL tetraspan subfamily member 5a
chr10_+_43039947 0.11 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr5_-_34185115 0.10 ENSDART00000192771
fibrinogen C domain containing 1
chr1_+_56900580 0.10 ENSDART00000152568
si:ch211-152f2.3
chr3_-_29508959 0.10 ENSDART00000055408
cytohesin 4a
chr7_-_69983948 0.09 ENSDART00000185827
potassium voltage-gated channel interacting protein 4
chr5_+_45007962 0.08 ENSDART00000010786
doublesex and mab-3 related transcription factor 2a
chr20_-_54924593 0.08 ENSDART00000151522
si:dkey-15f23.1
chr1_+_56873359 0.08 ENSDART00000152713
si:ch211-152f2.2
chr4_+_12292274 0.07 ENSDART00000061070
ENSDART00000150786
makorin, ring finger protein, 1
chr21_-_22812417 0.06 ENSDART00000079151
ENSDART00000112175
transient receptor potential cation channel, subfamily C, member 6a
chr21_+_40092301 0.06 ENSDART00000145150
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr1_+_57208005 0.06 ENSDART00000152410
si:dkey-27j5.10
chr11_-_44030962 0.06 ENSDART00000171910

chr15_+_28116129 0.06 ENSDART00000185157
unc-119 homolog a (C. elegans)
chr13_-_36621926 0.05 ENSDART00000057155
cyclin-dependent kinase inhibitor 3
chr18_+_10840071 0.05 ENSDART00000014496
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr9_-_20372977 0.05 ENSDART00000113418
immunoglobulin superfamily, member 3
chr1_+_57218301 0.04 ENSDART00000152476
ENSDART00000166419
si:dkey-27j5.8
chr14_+_4796168 0.04 ENSDART00000041468
adaptor-related protein complex 1 associated regulatory protein
chr9_-_33081978 0.04 ENSDART00000100918
zgc:172053
chr15_-_21239416 0.04 ENSDART00000155787
si:dkey-105h12.2
chr13_+_36622100 0.04 ENSDART00000133198
si:ch211-67f24.7
chr5_+_9405283 0.03 ENSDART00000127306
UDP glucuronosyltransferase 2 family, polypeptide A7
chr23_-_30960506 0.03 ENSDART00000142661
oxysterol binding protein-like 2a
chr18_+_50890749 0.02 ENSDART00000174109
si:ch1073-450f2.1
chr6_-_23931442 0.02 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr9_-_33062891 0.02 ENSDART00000161182
si:ch211-125e6.5
chr1_-_43862638 0.02 ENSDART00000145044
tachykinin receptor 3a
chr4_+_30363474 0.01 ENSDART00000168421
si:dkey-199m13.7
chr2_+_37480669 0.01 ENSDART00000029801
signal peptide peptidase-like 2
chr10_+_37083654 0.01 ENSDART00000132162
ENSDART00000029843
vascular endothelial zinc finger 1a
chr2_+_45068366 0.01 ENSDART00000142175
si:dkey-76d14.2
chr12_-_46145909 0.01 ENSDART00000139094
zgc:153932
chr1_+_57050899 0.01 ENSDART00000152601
si:ch211-1f22.14

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb8a+hoxb8b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.4 2.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.4 1.7 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 0.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.8 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 1.0 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.9 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.9 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.8 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.5 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.1 0.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.6 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 0.3 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.9 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 0.4 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.5 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.2 GO:0060300 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 1.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.9 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.7 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0007568 aging(GO:0007568)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.3 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.0 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.7 GO:0016586 RSC complex(GO:0016586)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 0.9 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 2.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.6 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 2.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 1.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 1.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus