Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for hoxb3a

Z-value: 0.95

Motif logo

Transcription factors associated with hoxb3a

Gene Symbol Gene ID Gene Info
ENSDARG00000029263 homeobox B3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb3adr11_v1_chr3_+_23743139_23743139-0.916.5e-04Click!

Activity profile of hoxb3a motif

Sorted Z-values of hoxb3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_23780334 2.87 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr10_-_21545091 2.29 ENSDART00000029122
ENSDART00000132207
zgc:165539
chr24_-_9979342 1.62 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr17_-_4245902 1.60 ENSDART00000151851
growth differentiation factor 3
chr2_-_38287987 1.59 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr25_+_5972690 1.52 ENSDART00000067517
si:ch211-11i22.4
chr3_+_3469600 1.47 ENSDART00000113616
zgc:171426
chr25_+_36292057 1.46 ENSDART00000152329
brambleberry
chr20_-_14114078 1.45 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr11_+_31864921 1.35 ENSDART00000180252
diaphanous-related formin 3
chr6_+_19948043 1.30 ENSDART00000182636
phosphoinositide-3-kinase, regulatory subunit 5
chr2_+_6253246 1.28 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr6_-_8362419 1.27 ENSDART00000142752
ENSDART00000135810
acid phosphatase 5a, tartrate resistant
chr9_+_18829360 1.21 ENSDART00000006514
general transcription factor IIF, polypeptide 2b
chr11_+_12811906 1.17 ENSDART00000123445
regulator of telomere elongation helicase 1
chr20_-_37813863 1.17 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr25_-_1323623 1.16 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calmodulin-like 4b
chr22_-_21897203 1.14 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr4_+_25917915 1.12 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr14_-_33481428 1.07 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lysosomal-associated membrane protein 2
chr21_-_32060993 1.07 ENSDART00000131651
si:ch211-160j14.2
chr22_+_17261801 1.04 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr3_-_60856157 1.04 ENSDART00000053502

chr5_+_65970235 1.03 ENSDART00000166432
solute carrier family 2 (facilitated glucose transporter), member 8
chr19_+_9231766 1.02 ENSDART00000190617
lysine (K)-specific methyltransferase 2Ba
chr5_+_37903790 1.00 ENSDART00000162470
transmembrane protease, serine 4b
chr5_+_13472234 1.00 ENSDART00000114069
ENSDART00000132406
cyclin and CBS domain divalent metal cation transport mediator 4b
chr2_+_54086436 1.00 ENSDART00000174581

chr7_+_23515966 0.97 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr12_-_18483348 0.94 ENSDART00000152757
testis expressed 2, like
chr21_-_13661631 0.94 ENSDART00000184408
patatin-like phospholipase domain containing 7a
chr12_-_48188928 0.94 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr6_+_59642695 0.94 ENSDART00000166373
ENSDART00000161030
R3H domain containing 2
chr19_-_18127808 0.93 ENSDART00000108627
sorting nexin 10a
chr7_+_13609457 0.93 ENSDART00000172857
ankyrin repeat and death domain containing 1A
chr17_+_43595692 0.91 ENSDART00000156271
cilia and flagella associated protein 99
chr19_-_18127629 0.90 ENSDART00000187722
sorting nexin 10a
chr8_-_19246342 0.88 ENSDART00000147172
abhydrolase domain containing 17Ab
chr20_+_14114258 0.88 ENSDART00000044937
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr5_-_37881345 0.86 ENSDART00000084819
Rho GTPase activating protein 35b
chr2_+_1988036 0.85 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr8_-_39822917 0.83 ENSDART00000067843
zgc:162025
chr18_+_27571448 0.82 ENSDART00000147886
CD82 molecule b
chr14_-_30905288 0.81 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr24_+_36204028 0.81 ENSDART00000063832
ENSDART00000155260
retinoblastoma binding protein 8
chr23_+_20523617 0.81 ENSDART00000176404
activity-dependent neuroprotector homeobox b
chr2_-_21819421 0.79 ENSDART00000121586
chromodomain helicase DNA binding protein 7
chr6_+_21001264 0.79 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr21_-_30254185 0.77 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr1_+_44523516 0.77 ENSDART00000147702
zinc finger, DHHC-type containing 5a
chr20_+_47491247 0.77 ENSDART00000113412
lin-28 homolog B (C. elegans)
chr19_+_1688727 0.76 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr6_-_12275836 0.74 ENSDART00000189980
plakophilin 4
chr13_-_31025505 0.74 ENSDART00000137709
WDFY family member 4
chr19_-_425145 0.72 ENSDART00000164905
dihydrouridine synthase 3-like (S. cerevisiae)
chr23_+_33947874 0.71 ENSDART00000136104
si:ch211-148l7.4
chr18_+_41768357 0.71 ENSDART00000192658
transient receptor potential cation channel, subfamily C, member 6b
chr4_-_72295710 0.71 ENSDART00000182983
si:cabz01071911.3
chr8_+_11325310 0.71 ENSDART00000142577
frataxin
chr9_-_32158288 0.70 ENSDART00000037182
ankyrin repeat domain 44
chr3_+_31087509 0.70 ENSDART00000129564
si:dkey-66i24.8
chr3_-_60886984 0.69 ENSDART00000170974
phosphatidylinositol transfer protein, cytoplasmic 1
chr20_+_27087539 0.68 ENSDART00000062094
transmembrane protein 251
chr13_-_36663358 0.68 ENSDART00000085319
son of sevenless homolog 2 (Drosophila)
chr8_-_53044300 0.68 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr4_-_77260727 0.68 ENSDART00000075770
zgc:162948
chr12_-_4249000 0.66 ENSDART00000059298
zgc:92313
chr25_+_15273370 0.66 ENSDART00000045659
t-complex 11, testis-specific-like 1
chr5_-_25733745 0.66 ENSDART00000051566
zgc:101016
chr17_+_24222190 0.65 ENSDART00000181698
ENSDART00000189411
EH domain binding protein 1
chr9_-_12034444 0.65 ENSDART00000038651
zinc finger protein 804A
chr23_-_32194397 0.64 ENSDART00000184206
ENSDART00000166682
nuclear receptor subfamily 4, group A, member 1
chr13_-_8692860 0.63 ENSDART00000058107
multiple coagulation factor deficiency 2
chr17_-_15189397 0.63 ENSDART00000133710
ENSDART00000110507
WD repeat and HMG-box DNA binding protein 1
chr7_-_40630698 0.63 ENSDART00000134547
ubiquitin protein ligase E3C
chr13_+_33688474 0.63 ENSDART00000161465

chr7_-_14446512 0.63 ENSDART00000041577
kinesin family member 7
chr3_+_22035863 0.62 ENSDART00000177169
cell division cycle 27
chr3_-_31086770 0.62 ENSDART00000103421
zgc:153292
chr6_+_3334710 0.62 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr8_-_43750062 0.62 ENSDART00000142243
unc-51 like autophagy activating kinase 1a
chr7_-_58251527 0.61 ENSDART00000114008
ENSDART00000185189
un-named hu7910
chr15_+_24795473 0.61 ENSDART00000139689
ENSDART00000141033
ENSDART00000100746
ENSDART00000135677
golgi SNAP receptor complex member 1
chr25_+_17860798 0.61 ENSDART00000146845
parathyroid hormone 1a
chr9_+_16241656 0.60 ENSDART00000154326
si:ch211-261p9.4
chr13_+_27770424 0.60 ENSDART00000159281
asparaginase like 1
chr17_-_14523722 0.59 ENSDART00000024726
dishevelled associated activator of morphogenesis 1a
chr25_+_35891342 0.59 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr6_-_42949184 0.58 ENSDART00000147208
ER degradation enhancer, mannosidase alpha-like 1
chr5_+_25733774 0.58 ENSDART00000137088
ENSDART00000098467
abhydrolase domain containing 17B
chr21_-_13662237 0.58 ENSDART00000091647
ENSDART00000151547
patatin-like phospholipase domain containing 7a
chr5_-_67629263 0.58 ENSDART00000133753
zinc finger and BTB domain containing 20
chr4_+_2482046 0.57 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr17_+_16429826 0.57 ENSDART00000136078
EF-hand calcium binding domain 11
chr6_+_2457455 0.56 ENSDART00000157456

chr7_-_22632690 0.56 ENSDART00000165245
si:dkey-112a7.4
chr25_-_37180969 0.56 ENSDART00000152338
tudor domain containing 12
chr7_-_64589920 0.56 ENSDART00000172619
ENSDART00000184113

chr16_+_9726038 0.55 ENSDART00000192988
ENSDART00000020859
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr24_-_38644937 0.55 ENSDART00000170194
solute carrier family 6, member 16b
chr18_+_34181655 0.54 ENSDART00000130831
ENSDART00000109535
guanine monophosphate synthase
chr6_+_29861288 0.54 ENSDART00000166782
discs, large homolog 1 (Drosophila)
chr4_-_8058214 0.54 ENSDART00000132228
WNK lysine deficient protein kinase 1b
chr23_-_28423222 0.53 ENSDART00000182058
complement component 1, q subcomponent-like 4
chr3_+_16724614 0.52 ENSDART00000182135
glycogen synthase 1 (muscle)
chr12_+_1492641 0.52 ENSDART00000152411
ubiquitin specific peptidase 22
chr3_+_19685873 0.52 ENSDART00000006490
tousled-like kinase 2
chr22_+_8979955 0.52 ENSDART00000144005
si:ch211-213a13.1
chr2_+_36112273 0.52 ENSDART00000191315
T-cell receptor alpha joining 35
chr8_-_7567815 0.52 ENSDART00000132536
host cell factor C1b
chr2_-_58075414 0.52 ENSDART00000161920
nectin cell adhesion molecule 4
chr7_-_22632518 0.52 ENSDART00000161046
si:dkey-112a7.4
chr4_-_14162327 0.52 ENSDART00000138656
si:dkey-234l24.1
chr7_-_12464412 0.51 ENSDART00000178723
ADAMTS-like 3
chr12_+_47698356 0.51 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr16_-_35329803 0.51 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
protein tyrosine phosphatase, receptor type, U, b
chr20_+_29209767 0.51 ENSDART00000141252
katanin p80 subunit B-like 1
chr11_+_11303458 0.51 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
chr2_-_17393216 0.50 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr8_+_52314542 0.50 ENSDART00000013059
ENSDART00000125241
drebrin-like b
chr9_+_38888025 0.50 ENSDART00000148306
microtubule-associated protein 2
chr11_+_1608348 0.50 ENSDART00000162438
si:dkey-40c23.3
chr20_+_19006703 0.50 ENSDART00000128435
PIN2/TERF1 interacting, telomerase inhibitor 1
chr13_+_28785814 0.49 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr21_-_40938382 0.49 ENSDART00000008593
Yip1 domain family, member 5
chr2_+_30182431 0.49 ENSDART00000004903
retinol dehydrogenase 10b
chr2_+_41524238 0.49 ENSDART00000122860
ENSDART00000017977
activin A receptor, type 1 like
chr25_+_34938317 0.48 ENSDART00000042678
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr7_-_5431841 0.48 ENSDART00000173073
Rho guanine nucleotide exchange factor (GEF) 11
chr2_+_36828746 0.48 ENSDART00000186638
nardilysin a (N-arginine dibasic convertase)
chr1_-_51710225 0.48 ENSDART00000057601
ENSDART00000152745
small nuclear ribonucleoprotein polypeptide B2
chr23_-_900795 0.48 ENSDART00000190517
ENSDART00000182849
ENSDART00000111456
ENSDART00000185430
RNA binding motif protein 10
chr21_+_11834880 0.47 ENSDART00000081661
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr11_-_44979281 0.47 ENSDART00000190972
LIM-domain binding 1b
chr3_+_35406998 0.47 ENSDART00000102994
retinoblastoma binding protein 6
chr23_-_14766902 0.46 ENSDART00000168113
glutathione synthetase
chr5_-_24542726 0.46 ENSDART00000182975
tRNA methyltransferase 2 homolog A
chr22_+_737211 0.46 ENSDART00000017305
zinc finger protein 76
chr6_+_37655078 0.46 ENSDART00000122199
ENSDART00000065127
cytoplasmic FMR1 interacting protein 1
chr15_+_17345609 0.45 ENSDART00000111753
vacuole membrane protein 1
chr19_-_32042105 0.45 ENSDART00000088358
zinc finger protein 704
chr14_-_48961056 0.45 ENSDART00000124192
si:dkeyp-121d2.7
chr6_+_40832635 0.44 ENSDART00000011931
RuvB-like AAA ATPase 1
chr23_+_4741543 0.44 ENSDART00000144761
Raf-1 proto-oncogene, serine/threonine kinase a
chr13_-_30142087 0.44 ENSDART00000110157
trypsin domain containing 1
chr18_-_44526940 0.43 ENSDART00000077125
amyloid beta (A4) precursor-like protein 2
chr19_+_14351560 0.43 ENSDART00000182732
AT rich interactive domain 1Ab (SWI-like)
chr6_-_37744430 0.42 ENSDART00000150177
ENSDART00000149722
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr23_+_45966436 0.42 ENSDART00000172160

chr12_-_28349026 0.42 ENSDART00000183768
ENSDART00000152998
zgc:195081
chr7_+_24729558 0.41 ENSDART00000111542
ENSDART00000170100
shroom family member 4
chr6_+_29860776 0.41 ENSDART00000028406
discs, large homolog 1 (Drosophila)
chr16_-_30847192 0.41 ENSDART00000191106
ENSDART00000128158
protein tyrosine kinase 2ab
chr23_+_4709607 0.41 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr22_+_14051894 0.41 ENSDART00000142548
aldehyde oxidase 6
chr2_-_15031858 0.40 ENSDART00000191478
holocytochrome c synthase a
chr11_-_875381 0.40 ENSDART00000173325
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr9_-_11676491 0.40 ENSDART00000022358
zinc finger CCCH-type containing 15
chr2_-_1622641 0.39 ENSDART00000082143
protein kinase, cAMP-dependent, catalytic, beta b
chr21_-_11199366 0.39 ENSDART00000167666
DnaJ (Hsp40) homolog, subfamily C, member 21
chr1_+_230363 0.39 ENSDART00000153285
transcription factor Dp-1, b
chr5_-_35161877 0.38 ENSDART00000139673
FCH domain only 2
chr16_-_36748374 0.38 ENSDART00000133310
phosphoinositide-3-kinase, regulatory subunit 4
chr20_-_45060241 0.38 ENSDART00000185227
kelch-like family member 29
chr7_+_19835569 0.38 ENSDART00000149812
ovo-like zinc finger 1a
chr1_-_18585046 0.37 ENSDART00000147228
family with sequence similarity 114, member A1
chr14_-_36397768 0.37 ENSDART00000185199
ENSDART00000052562
spermatogenesis associated 4
chr4_-_14173138 0.37 ENSDART00000142487
si:dkey-234l24.7
chr9_-_35334642 0.36 ENSDART00000157195
neural cell adhesion molecule 2
chr13_-_8692432 0.36 ENSDART00000058106
multiple coagulation factor deficiency 2
chr17_-_37195354 0.36 ENSDART00000190963
additional sex combs like transcriptional regulator 2
chr17_+_44697604 0.36 ENSDART00000156625
placental growth factor b
chr19_+_7120380 0.35 ENSDART00000000698
proteasome subunit beta 9a
chr20_+_46513651 0.35 ENSDART00000152977
zinc finger CCCH-type containing 14
chr20_+_38458084 0.35 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr20_+_29209926 0.35 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr5_+_66043820 0.34 ENSDART00000016019
Janus kinase 2b
chr2_-_33645411 0.34 ENSDART00000114663
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr15_-_679478 0.34 ENSDART00000115375
ENSDART00000156148
zgc:171901
chr17_+_38030327 0.34 ENSDART00000085481
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr5_+_66044128 0.34 ENSDART00000165573
Janus kinase 2b
chr13_+_42676202 0.34 ENSDART00000099782
mitochondrial ribosomal protein L14
chr2_+_49232559 0.33 ENSDART00000154285
ENSDART00000175147
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr21_-_41065369 0.33 ENSDART00000143749
leucyl-tRNA synthetase b
chr6_+_36839509 0.33 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr9_+_12890161 0.32 ENSDART00000146477
si:ch211-167j6.4
chr2_+_36828243 0.32 ENSDART00000135754
ENSDART00000140474
nardilysin a (N-arginine dibasic convertase)
chr9_-_10068004 0.32 ENSDART00000011922
ENSDART00000162818
speckle-type POZ protein-like a
chr5_+_69747417 0.31 ENSDART00000153717
si:ch211-275j6.5
chr17_+_38602602 0.31 ENSDART00000187996
coiled-coil domain containing 88C
chr1_-_23157583 0.31 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr15_+_34592215 0.31 ENSDART00000099776
tetraspanin 13a
chr2_+_10007113 0.31 ENSDART00000155213
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr16_-_29397395 0.31 ENSDART00000130757
toll-like receptor 18
chr20_+_29209615 0.30 ENSDART00000062350
katanin p80 subunit B-like 1
chr2_+_25315591 0.30 ENSDART00000161386
fibronectin type III domain containing 3Ba
chr12_-_28975705 0.30 ENSDART00000129173
zinc finger protein 646
chr25_+_6266009 0.30 ENSDART00000148995
solute carrier family 25, member 44 a
chr18_+_8833251 0.29 ENSDART00000143519
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr4_+_77943184 0.29 ENSDART00000159094
protein kinase C and casein kinase substrate in neurons 2

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb3a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0070986 left/right axis specification(GO:0070986)
0.3 1.6 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 1.5 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.3 0.8 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.2 2.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.6 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.8 GO:0097065 anterior head development(GO:0097065)
0.1 1.2 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.6 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.6 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.5 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.4 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.3 GO:0045453 bone resorption(GO:0045453)
0.1 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.5 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 1.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.0 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.3 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.6 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.9 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.0 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.4 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.3 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.8 GO:0048798 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.2 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0070285 pigment cell development(GO:0070285)
0.1 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.6 GO:0051984 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.2 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.0 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 1.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.9 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.5 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.3 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.4 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 1.3 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.3 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0045191 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.3 GO:0070252 actin-mediated cell contraction(GO:0070252)
0.0 0.1 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.6 GO:0021986 habenula development(GO:0021986)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 1.2 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 1.3 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.3 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.5 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 1.0 GO:0033391 chromatoid body(GO:0033391)
0.2 1.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 0.6 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0070724 BMP receptor complex(GO:0070724)
0.1 1.3 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.4 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0035060 brahma complex(GO:0035060)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.4 GO:0010008 endosome membrane(GO:0010008)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0030428 cell septum(GO:0030428)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 3.1 GO:0005912 adherens junction(GO:0005912)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 0.8 GO:0070336 flap-structured DNA binding(GO:0070336)
0.2 1.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 2.9 GO:0032190 acrosin binding(GO:0032190)
0.2 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.5 GO:0043295 glutathione binding(GO:0043295)
0.1 0.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.4 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.8 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 2.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.3 PID ATM PATHWAY ATM pathway
0.0 2.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)