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PRJNA195909:zebrafish embryo and larva development
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Results for hoxb1a+hoxb1b-2
Z-value: 0.90
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Transcription factors associated with hoxb1a+hoxb1b-2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxb1a | dr11_v1_chr3_+_23768898_23768898 | 0.26 | 5.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_29952719 Show fit | 2.02 |
ENSDART00000173737
|
alpha-tropomyosin |
|
| chr16_+_1383914 Show fit | 1.97 |
ENSDART00000185089
|
ceramide synthase 2b |
|
| chr6_+_29791164 Show fit | 1.73 |
ENSDART00000017424
|
prothymosin, alpha a |
|
| chr25_+_20215964 Show fit | 1.62 |
ENSDART00000139235
|
troponin T2d, cardiac |
|
| chr14_-_36378494 Show fit | 1.52 |
ENSDART00000058503
|
glycoprotein M6Aa |
|
| chr25_+_20216159 Show fit | 1.46 |
ENSDART00000048642
|
troponin T2d, cardiac |
|
| chr1_-_38709551 Show fit | 1.42 |
ENSDART00000128794
|
glycoprotein M6Ab |
|
| chr21_-_28920245 Show fit | 1.34 |
ENSDART00000132884
|
CXXC finger protein 5a |
|
| chr14_+_34547554 Show fit | 1.31 |
ENSDART00000074819
|
gamma-aminobutyric acid (GABA) A receptor, pi |
|
| chr2_+_55984788 Show fit | 1.22 |
ENSDART00000183599
|
nicotinamide riboside kinase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxb1a+hoxb1b-2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | GO:0006937 | regulation of muscle contraction(GO:0006937) |
| 0.0 | 2.0 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 1.9 | GO:0061515 | myeloid cell development(GO:0061515) |
| 0.1 | 1.4 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.0 | 1.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 1.1 | GO:0071542 | dopaminergic neuron differentiation(GO:0071542) |
| 0.0 | 1.1 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.0 | 1.0 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.3 | 0.9 | GO:0031645 | negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645) |
| 0.1 | 0.9 | GO:0021661 | rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | GO:0005861 | troponin complex(GO:0005861) |
| 0.2 | 2.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 1.3 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 1.1 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.9 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 0.8 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.7 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.7 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.1 | GO:0030172 | troponin C binding(GO:0030172) troponin I binding(GO:0031013) |
| 0.1 | 2.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 2.0 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.2 | 1.7 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) |
| 0.0 | 1.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 1.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 1.3 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.2 | 1.2 | GO:0050262 | ribosylnicotinamide kinase activity(GO:0050262) |
| 0.0 | 1.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.4 | 1.1 | GO:1903136 | cuprous ion binding(GO:1903136) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 0.8 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.7 | PID BMP PATHWAY | BMP receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.8 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |