PRJNA195909:zebrafish embryo and larva development

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
hoxb10a Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000011579	homeobox B10a
hoxc10a Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000070348	homeobox C10a

Gene	Promoter	Pearson corr. coef.	P-value	Plot
hoxb10a	dr11_v1_chr3_+_23669267_23669267	0.90	9.0e-04	Click!
hoxc10a	dr11_v1_chr23_+_36083529_36083617	0.85	3.7e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr23_+_10146542 Show fit	1.58	ENSDART00000048073	zgc:171775 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171775
chr3_-_31804481 Show fit	1.46	ENSDART00000028270	gfap Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glial fibrillary acidic protein
chr23_+_27068225 Show fit	1.41	ENSDART00000054238	mipa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	major intrinsic protein of lens fiber a
chr16_-_45917322 Show fit	1.19	ENSDART00000060822	afp4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	antifreeze protein type IV
chr2_+_2223837 Show fit	1.17	ENSDART00000101038 ENSDART00000129354	tmie Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane inner ear
chr25_+_20089986 Show fit	1.15	ENSDART00000143441 ENSDART00000184073	tnni4b.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin I4b, tandem duplicate 2
chr6_+_52790049 Show fit	1.15	ENSDART00000002571	matn4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	matrilin 4
chr2_-_35566938 Show fit	1.09	ENSDART00000029006 ENSDART00000077178 ENSDART00000125298	tnn Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tenascin N
chr23_+_39606108 Show fit	1.09	ENSDART00000109464	g0s2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	G0/G1 switch 2
chr10_-_29903165 Show fit	1.01	ENSDART00000078800	lim2.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	lens intrinsic membrane protein 2.1
chr1_-_38195012 Show fit	0.92	ENSDART00000020409	hand2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	heart and neural crest derivatives expressed 2
chr12_+_27117609 Show fit	0.88	ENSDART00000076154	hoxb8b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	homeobox B8b
chr19_-_15855427 Show fit	0.86	ENSDART00000133059	cited4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr25_-_31423493 Show fit	0.80	ENSDART00000027661	myod1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myogenic differentiation 1
chr6_-_60147517 Show fit	0.80	ENSDART00000083453	slc32a1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 32 (GABA vesicular transporter), member 1
chr13_+_22264914 Show fit	0.78	ENSDART00000060576	myoz1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myozenin 1a
chr20_+_26538137 Show fit	0.76	ENSDART00000045397	stx11b.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	syntaxin 11b, tandem duplicate 1
chr9_-_1939232 Show fit	0.76	ENSDART00000146131	hoxd3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	homeobox D3a
chr6_+_35362225 Show fit	0.74	ENSDART00000133783 ENSDART00000102483	rgs4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of G protein signaling 4
chr16_+_50969248 Show fit	0.74	ENSDART00000172068	si:dkeyp-97a10.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-97a10.2
chr12_-_20373058 Show fit	0.72	ENSDART00000066382	aqp8a.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	aquaporin 8a, tandem duplicate 1
chr19_+_19762183 Show fit	0.71	ENSDART00000163611 ENSDART00000187604	hoxa3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	homeobox A3a
chr19_+_17385561 Show fit	0.69	ENSDART00000141397 ENSDART00000143913 ENSDART00000133626	rpl15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L15
chr18_+_19974289 Show fit	0.67	ENSDART00000090334 ENSDART00000192982	skor1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SKI family transcriptional corepressor 1b
chr14_+_30279391 Show fit	0.66	ENSDART00000172794	fgl1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	fibrinogen-like 1
chr7_+_60111581 Show fit	0.62	ENSDART00000087093	hspa12b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	heat shock protein 12B
chr22_-_4644484 Show fit	0.60	ENSDART00000167748	fbn2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	fibrillin 2b
chr12_+_5081759 Show fit	0.60	ENSDART00000164178	prrt2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proline-rich transmembrane protein 2
chr10_+_36650222 Show fit	0.59	ENSDART00000126963	ucp3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	uncoupling protein 3
chr24_-_27473771 Show fit	0.57	ENSDART00000139874	cxl34b.11 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CX chemokine ligand 34b, duplicate 11
chr6_+_27624023 Show fit	0.56	ENSDART00000147789	slco2a1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier organic anion transporter family, member 2A1
chr17_+_33453689 Show fit	0.56	ENSDART00000156894	rin3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Ras and Rab interactor 3
chr11_+_30244356 Show fit	0.55	ENSDART00000036050 ENSDART00000150080	rs1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoschisin 1a
chr20_+_52546186 Show fit	0.53	ENSDART00000110777 ENSDART00000153377 ENSDART00000153013 ENSDART00000042704	eef1db Links NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr5_+_15202495 Show fit	0.50	ENSDART00000144915	tbx1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	T-box 1
chr19_-_14191592 Show fit	0.50	ENSDART00000164594	tbxta Links NCBI UniProt ZFIN ENSEMBL Google Show fit	T-box transcription factor Ta
chr11_+_36158134 Show fit	0.48	ENSDART00000189827 ENSDART00000163330	grm2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamate receptor, metabotropic 2b
chr4_+_5741733 Show fit	0.48	ENSDART00000110243	pou3f2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	POU class 3 homeobox 2a
chr19_-_10881486 Show fit	0.48	ENSDART00000168852 ENSDART00000160438	PSMD4 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit psmd4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome 26S subunit, non-ATPase 4 proteasome 26S subunit, non-ATPase 4a
chr11_-_18253111 Show fit	0.46	ENSDART00000125984	mustn1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	musculoskeletal, embryonic nuclear protein 1b
chr23_+_25354856 Show fit	0.45	ENSDART00000109023 ENSDART00000147440	fmnl3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	formin-like 3
chr19_+_19761966 Show fit	0.45	ENSDART00000163697	hoxa3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	homeobox A3a
chr21_-_25756119 Show fit	0.44	ENSDART00000002341	cldnc Links NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin c
chr7_+_25059845 Show fit	0.42	ENSDART00000077215	ppp2r5b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein phosphatase 2, regulatory subunit B', beta
chr14_+_22114918 Show fit	0.39	ENSDART00000166610	tmx2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	thioredoxin-related transmembrane protein 2a
chr7_+_30875273 Show fit	0.39	ENSDART00000173693	apba2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	amyloid beta (A4) precursor protein-binding, family A, member 2b
chr13_-_50108337 Show fit	0.39	ENSDART00000133308	nid1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nidogen 1a
chr16_-_7443388 Show fit	0.39	ENSDART00000017445	prdm1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	PR domain containing 1a, with ZNF domain
chr9_-_32753535 Show fit	0.38	ENSDART00000060006	olig2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	oligodendrocyte lineage transcription factor 2
chr4_+_37406676 Show fit	0.37	ENSDART00000130981	si:ch73-134f24.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-134f24.1
chr5_-_48307804 Show fit	0.37	ENSDART00000182831 ENSDART00000186920 ENSDART00000183585	mef2cb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myocyte enhancer factor 2cb
chr24_+_12913329 Show fit	0.35	ENSDART00000141829	si:dkeyp-28d2.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-28d2.4
chr1_-_35924495 Show fit	0.35	ENSDART00000184424	smad1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SMAD family member 1
chr13_-_42749916 Show fit	0.34	ENSDART00000140019	capn2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	calpain 2, (m/II) large subunit a
chr2_+_52847049 Show fit	0.33	ENSDART00000121980	creb3l3b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cAMP responsive element binding protein 3-like 3b
chr24_-_8732519 Show fit	0.32	ENSDART00000082351	tfap2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transcription factor AP-2 alpha
chr25_-_13614863 Show fit	0.31	ENSDART00000121859	fa2h Links NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid 2-hydroxylase
chr13_+_31108334 Show fit	0.31	ENSDART00000142245	arhgap22 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 22
chr8_+_18588551 Show fit	0.31	ENSDART00000177476 ENSDART00000063539	prrg1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proline rich Gla (G-carboxyglutamic acid) 1
chr8_-_25120231 Show fit	0.30	ENSDART00000147308	amigo1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	adhesion molecule with Ig-like domain 1
chr11_-_2700397 Show fit	0.30	ENSDART00000082511	si:ch211-160o17.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-160o17.6
chr5_-_26181863 Show fit	0.30	ENSDART00000098500	ccdc125 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	coiled-coil domain containing 125
chr19_+_4916233 Show fit	0.30	ENSDART00000159512	ppp1r1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr10_-_22845485 Show fit	0.30	ENSDART00000079454	vamp2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	vesicle-associated membrane protein 2
chr2_+_20406399 Show fit	0.28	ENSDART00000006817 ENSDART00000137848	palmda Links NCBI UniProt ZFIN ENSEMBL Google Show fit	palmdelphin a
chr9_-_41784799 Show fit	0.28	ENSDART00000144573 ENSDART00000112542 ENSDART00000190486	obsl1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	obscurin-like 1b
chr7_-_69025306 Show fit	0.27	ENSDART00000180796	CABZ01057488.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr17_-_12389259 Show fit	0.27	ENSDART00000185724	snap25b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptosomal-associated protein, 25b
chr19_-_10881141 Show fit	0.27	ENSDART00000162793	psmd4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome 26S subunit, non-ATPase 4a
chr19_-_17385548 Show fit	0.26	ENSDART00000162383	nkiras1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	NFKB inhibitor interacting Ras-like 1
chr11_-_6265574 Show fit	0.24	ENSDART00000181974 ENSDART00000104405	ccl25b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 25b
chr2_-_6039757 Show fit	0.24	ENSDART00000013079	scp2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sterol carrier protein 2a
chr16_+_46459680 Show fit	0.23	ENSDART00000101698	rpz3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	rapunzel 3
chr13_-_37519774 Show fit	0.23	ENSDART00000141420 ENSDART00000185478	sgpp1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sphingosine-1-phosphate phosphatase 1
chr10_+_26612321 Show fit	0.22	ENSDART00000134322	fhl1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	four and a half LIM domains 1b
chr3_+_24134418 Show fit	0.22	ENSDART00000156204	si:ch211-246i5.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-246i5.5
chr7_+_48761875 Show fit	0.21	ENSDART00000003690	acana Links NCBI UniProt ZFIN ENSEMBL Google Show fit	aggrecan a
chr5_+_24245682 Show fit	0.21	ENSDART00000049003	atp6v1aa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase H+ transporting V1 subunit Aa
chr8_+_2487250 Show fit	0.21	ENSDART00000081325	dynll1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	dynein, light chain, LC8-type 1
chr24_+_1042594 Show fit	0.20	ENSDART00000109117	si:dkey-192l18.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-192l18.9
chr4_-_56898328 Show fit	0.20	ENSDART00000169189	si:dkey-269o24.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-269o24.6
chr13_+_36585399 Show fit	0.20	ENSDART00000030211	gmfb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glia maturation factor, beta
chr8_+_2487883 Show fit	0.20	ENSDART00000101841	dynll1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	dynein, light chain, LC8-type 1
chr1_+_40801448 Show fit	0.19	ENSDART00000187394	cpz Links NCBI UniProt ZFIN ENSEMBL Google Show fit	carboxypeptidase Z
chr12_-_26430507 Show fit	0.19	ENSDART00000153214	synpo2lb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptopodin 2-like b
chr7_-_45076131 Show fit	0.19	ENSDART00000110590	zgc:194678 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194678
chr14_-_30967284 Show fit	0.18	ENSDART00000149435	il2rgb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 2 receptor, gamma b
chr5_+_26913120 Show fit	0.18	ENSDART00000126609	tbx3b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	T-box 3b
chr5_-_24174956 Show fit	0.18	ENSDART00000137631	si:ch211-137i24.10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-137i24.10
chr10_+_2587234 Show fit	0.18	ENSDART00000126937	wu:fb59d01 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	wu:fb59d01
chr9_+_30720048 Show fit	0.18	ENSDART00000146115	klf12b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Kruppel-like factor 12b
chr10_-_34772211 Show fit	0.18	ENSDART00000145450 ENSDART00000134307	dclk1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	doublecortin-like kinase 1a
chr15_+_37559570 Show fit	0.17	ENSDART00000085522	hspb6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	heat shock protein, alpha-crystallin-related, b6
chr4_+_7391400 Show fit	0.17	ENSDART00000169111 ENSDART00000186395	tnni4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin I4a
chr16_+_25535993 Show fit	0.16	ENSDART00000077436	mylipb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin regulatory light chain interacting protein b
chr18_-_15559817 Show fit	0.16	ENSDART00000061681	si:ch211-245j22.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-245j22.3
chr6_-_19683406 Show fit	0.15	ENSDART00000158041	cfap52 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cilia and flagella associated protein 52
chr24_-_12689571 Show fit	0.15	ENSDART00000015517	pdcd6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	programmed cell death 6
chr9_+_41024973 Show fit	0.15	ENSDART00000014660 ENSDART00000144467	ormdl1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ORMDL sphingolipid biosynthesis regulator 1
chr7_-_26457208 Show fit	0.15	ENSDART00000173519	zgc:172079 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:172079
chr16_+_13883872 Show fit	0.14	ENSDART00000101304 ENSDART00000136005	atg12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ATG12 autophagy related 12 homolog (S. cerevisiae)
chr7_-_29341233 Show fit	0.14	ENSDART00000140938 ENSDART00000147251	trpm1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transient receptor potential cation channel, subfamily M, member 1a
chr11_+_14284866 Show fit	0.14	ENSDART00000163729	si:ch211-262i1.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-262i1.3
chr6_+_13083146 Show fit	0.14	ENSDART00000172158	l3hypdh Links NCBI UniProt ZFIN ENSEMBL Google Show fit	trans-L-3-hydroxyproline dehydratase
chr23_-_27571667 Show fit	0.14	ENSDART00000008174	pfkma Links NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphofructokinase, muscle a
chr24_-_31846366 Show fit	0.13	ENSDART00000155295	steap2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	STEAP family member 2, metalloreductase
chr20_+_9763364 Show fit	0.13	ENSDART00000053834	psmc6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome 26S subunit, ATPase 6
chr7_-_41338923 Show fit	0.13	ENSDART00000099138	ncf2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	neutrophil cytosolic factor 2
chr2_+_5927255 Show fit	0.12	ENSDART00000152866	si:ch211-168b3.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-168b3.2
chr8_+_30709685 Show fit	0.12	ENSDART00000133989	upb1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ureidopropionase, beta
chr20_+_46183505 Show fit	0.12	ENSDART00000060799	taar13b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	trace amine associated receptor 13b
chr21_-_21537452 Show fit	0.12	ENSDART00000142549	or133-7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	odorant receptor, family H, subfamily 133, member 7
chr23_+_7379728 Show fit	0.12	ENSDART00000012194	gata5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	GATA binding protein 5
chr11_+_2699951 Show fit	0.11	ENSDART00000082512	tmem167b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 167B
chr19_+_42469058 Show fit	0.11	ENSDART00000076915	si:dkey-166k12.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-166k12.1
chr20_+_6543674 Show fit	0.11	ENSDART00000134204	tns3.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tensin 3, tandem duplicate 1
chr4_+_7391110 Show fit	0.11	ENSDART00000160708 ENSDART00000187823	tnni4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin I4a
chr19_+_19599528 Show fit	0.11	ENSDART00000163054	hibadha Links NCBI UniProt ZFIN ENSEMBL Google Show fit	3-hydroxyisobutyrate dehydrogenase a
chr2_+_21855291 Show fit	0.10	ENSDART00000186204	ca8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	carbonic anhydrase VIII
chr20_+_27464721 Show fit	0.10	ENSDART00000189552	kif26aa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 26Aa
chr18_+_7363242 Show fit	0.10	ENSDART00000133375	si:dkey-30c15.17 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-30c15.17
chr17_+_45395846 Show fit	0.10	ENSDART00000058793	nenf Links NCBI UniProt ZFIN ENSEMBL Google Show fit	neudesin neurotrophic factor
chr10_+_40606084 Show fit	0.10	ENSDART00000133119	si:ch211-238p8.24 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-238p8.24
chr12_+_34051848 Show fit	0.10	ENSDART00000153276	cyth1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cytohesin 1b
chr4_+_2267641 Show fit	0.10	ENSDART00000165503	si:ch73-89b15.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-89b15.3
chr21_-_21594841 Show fit	0.10	ENSDART00000132490	or133-2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	odorant receptor, family H, subfamily 133, member 2
chr22_+_25331766 Show fit	0.10	ENSDART00000155006 ENSDART00000155836	si:ch211-226h8.15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-226h8.15
chr25_-_10907786 Show fit	0.10	ENSDART00000172490	CR339041.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr1_+_51407520 Show fit	0.10	ENSDART00000074294	actr2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ARP2 actin related protein 2a homolog
chr23_+_24085531 Show fit	0.10	ENSDART00000139710	ttll10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tubulin tyrosine ligase-like family, member 10
chr24_-_27452488 Show fit	0.10	ENSDART00000136433	ccl34b.8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 34b, duplicate 8
chr2_+_35595454 Show fit	0.10	ENSDART00000098734	cacybp Links NCBI UniProt ZFIN ENSEMBL Google Show fit	calcyclin binding protein
chr6_+_30703828 Show fit	0.09	ENSDART00000104628	insl5a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	insulin-like 5a
chr16_-_2558653 Show fit	0.09	ENSDART00000110365	adcy3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	adenylate cyclase 3a
chr21_-_20328375 Show fit	0.08	ENSDART00000079593	slc26a1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 26 (anion exchanger), member 1
chr22_+_18187857 Show fit	0.08	ENSDART00000166300	mef2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myocyte enhancer factor 2b
chr19_+_2590182 Show fit	0.08	ENSDART00000162293	si:ch73-345f18.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-345f18.3
chr6_+_36877968 Show fit	0.08	ENSDART00000155187	traf3ip2l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TRAF3 interacting protein 2-like
chr16_+_45746549 Show fit	0.08	ENSDART00000190403	paqr6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	progestin and adipoQ receptor family member VI
chr22_+_26853254 Show fit	0.08	ENSDART00000182487	tmem186 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 186
chr24_-_27461295 Show fit	0.08	ENSDART00000110748	ccl34b.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 34b, duplicate 9
chr5_+_23136544 Show fit	0.07	ENSDART00000003428 ENSDART00000109340 ENSDART00000171039 ENSDART00000178821	prps1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoribosyl pyrophosphate synthetase 1A
chr11_+_36231248 Show fit	0.07	ENSDART00000131104	GPR62 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-213o11.11
chr1_-_37377509 Show fit	0.07	ENSDART00000113542	tnip2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNFAIP3 interacting protein 2
chr7_+_24165371 Show fit	0.07	ENSDART00000173472	si:ch211-216p19.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-216p19.5
chr19_+_5418006 Show fit	0.07	ENSDART00000132874	eif1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 1B
chr24_+_1294176 Show fit	0.06	ENSDART00000106637	si:ch73-134f24.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-134f24.1
chr6_+_52869892 Show fit	0.06	ENSDART00000146143	si:dkeyp-3f10.16 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-3f10.16
chr17_+_8184649 Show fit	0.06	ENSDART00000091818	tulp4b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tubby like protein 4b
chr21_+_4957685 Show fit	0.06	ENSDART00000144166	B3GNT10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-29c22.2
chr8_+_3379815 Show fit	0.06	ENSDART00000155995	FUT9 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:136963
chr2_-_34072218 Show fit	0.06	ENSDART00000184618	eif2b3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 2B, subunit 3 gamma
chr6_-_39653972 Show fit	0.06	ENSDART00000155859	larp4ab Links NCBI UniProt ZFIN ENSEMBL Google Show fit	La ribonucleoprotein domain family, member 4Ab
chr16_-_21038015 Show fit	0.06	ENSDART00000059239	snx10b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sorting nexin 10b
chr7_-_32599669 Show fit	0.06	ENSDART00000173752	kcna4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	potassium voltage-gated channel, shaker-related subfamily, member 4
chr22_+_18188045 Show fit	0.05	ENSDART00000140106	mef2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myocyte enhancer factor 2b
chr12_+_19356623 Show fit	0.05	ENSDART00000078284	dmc1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	DNA meiotic recombinase 1
chr25_-_13614702 Show fit	0.05	ENSDART00000165510 ENSDART00000190959	fa2h Links NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid 2-hydroxylase
chr17_-_15747296 Show fit	0.04	ENSDART00000153970	cx52.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	connexin 52.7
chr10_+_506538 Show fit	0.04	ENSDART00000141713	si:ch211-242f23.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-242f23.3
chr1_+_1915967 Show fit	0.03	ENSDART00000131463	si:ch211-132g1.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-132g1.1
chr7_-_17457872 Show fit	0.03	ENSDART00000191583 ENSDART00000192609	nitr3c Links NCBI UniProt ZFIN ENSEMBL Google Show fit	novel immune-type receptor 3c
chr25_-_32449235 Show fit	0.03	ENSDART00000115343	atp8b4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase phospholipid transporting 8B4
chr16_+_25664078 Show fit	0.03	ENSDART00000154024	nsmce2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr18_+_20825375 Show fit	0.03	ENSDART00000090100 ENSDART00000146751 ENSDART00000141686	ttc23 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tetratricopeptide repeat domain 23
chr20_+_46172649 Show fit	0.03	ENSDART00000111317	taar13e Links NCBI UniProt ZFIN ENSEMBL Google Show fit	trace amine associated receptor 13e
chr10_+_40583930 Show fit	0.03	ENSDART00000134523	taar18j Links NCBI UniProt ZFIN ENSEMBL Google Show fit	trace amine associated receptor 18j
chr13_-_50546634 Show fit	0.03	ENSDART00000192127	CU570781.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr16_+_25664387 Show fit	0.02	ENSDART00000184394	nsmce2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr7_-_60096318 Show fit	0.02	ENSDART00000189125	BX511067.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr13_-_12660318 Show fit	0.02	ENSDART00000008498	adh8a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	alcohol dehydrogenase 8a
chr15_-_28860282 Show fit	0.02	ENSDART00000156738	gpr4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein-coupled receptor 4
chr17_-_15746898 Show fit	0.02	ENSDART00000180079	cx52.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	connexin 52.7
chr8_-_19487327 Show fit	0.02	ENSDART00000111710	edem3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ER degradation enhancer, mannosidase alpha-like 3
chr2_+_21855036 Show fit	0.02	ENSDART00000140012	ca8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	carbonic anhydrase VIII
chr17_+_33226955 Show fit	0.02	ENSDART00000063333	pomca Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proopiomelanocortin a
chr12_+_19191787 Show fit	0.02	ENSDART00000152892	slc16a8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 16 (monocarboxylate transporter), member 8
chr9_+_27339505 Show fit	0.01	ENSDART00000011822	slc10a2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_27317174 Show fit	0.01	ENSDART00000193058	sox6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SRY (sex determining region Y)-box 6
chr11_+_36683859 Show fit	0.01	ENSDART00000170102	si:ch211-11c3.12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-11c3.12
chr23_-_24047054 Show fit	0.01	ENSDART00000184308 ENSDART00000185902	CR925720.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr22_-_8594846 Show fit	0.01	ENSDART00000081690 ENSDART00000192241	si:ch73-27e22.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-27e22.1
chr17_-_47090440 Show fit	0.01	ENSDART00000163542	CABZ01056321.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr4_+_51552434 Show fit	0.00	ENSDART00000165016	si:dkey-165e24.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-165e24.1

View svg image
View png image

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.2	0.5	GO:0043282	pharyngeal muscle development(GO:0043282)
0.2	0.6	GO:0061323	cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136) cell proliferation involved in heart valve development(GO:2000793)
0.2	0.9	GO:0071908	determination of intestine left/right asymmetry(GO:0071908)
0.2	1.2	GO:0060017	parathyroid gland development(GO:0060017)
0.2	1.4	GO:0006833	water transport(GO:0006833)
0.1	0.5	GO:0072045	convergent extension involved in nephron morphogenesis(GO:0072045)
0.1	0.8	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.4	GO:0021742	abducens nucleus development(GO:0021742)
0.1	0.5	GO:0035988	chondrocyte proliferation(GO:0035988)
0.1	0.2	GO:2000471	regulation of hematopoietic stem cell migration(GO:2000471)
0.1	0.6	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	0.4	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1	1.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.7	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0032370	positive regulation of lipid transport(GO:0032370)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.4	GO:0001709	cell fate determination(GO:0001709)
0.0	1.2	GO:0060030	dorsal convergence(GO:0060030)
0.0	0.1	GO:2000303	regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0	0.2	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.0	0.6	GO:0071715	icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.0	0.1	GO:0015677	copper ion import(GO:0015677)
0.0	1.0	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.1	GO:0048618	post-embryonic foregut morphogenesis(GO:0048618)
0.0	1.4	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.3	GO:0014034	neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0	0.1	GO:0019483	beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0	0.1	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.0	0.3	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.4	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.0	0.3	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.6	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.7	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.3	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0061615	glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.0	GO:0042148	strand invasion(GO:0042148)
0.0	0.1	GO:1905168	positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.6	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	1.5	GO:0007160	cell-matrix adhesion(GO:0007160)
0.0	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	1.0	GO:0031018	endocrine pancreas development(GO:0031018)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	0.9	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	0.8	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.3	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	1.4	GO:0005861	troponin complex(GO:0005861)
0.0	0.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.4	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	1.5	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	GO:0015250	water channel activity(GO:0015250)
0.1	0.6	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.4	GO:0080132	fatty acid alpha-hydroxylase activity(GO:0080132)
0.1	0.8	GO:0070888	E-box binding(GO:0070888)
0.1	0.8	GO:0031433	telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1	0.5	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.1	0.8	GO:0015295	solute:proton symporter activity(GO:0015295)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.6	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	1.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0008442	3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.4	GO:0072542	phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	1.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	1.1	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.4	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	1.0	GO:0008009	chemokine activity(GO:0008009)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0000150	recombinase activity(GO:0000150)
0.0	0.7	GO:0046332	SMAD binding(GO:0046332)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.7	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.4	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	1.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	2.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.5	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism