Project
PRJNA195909:zebrafish embryo and larva development
Navigation
Downloads
Results for hoxa4a+hoxc3a
Z-value: 0.78
Motif logo
Transcription factors associated with hoxa4a+hoxc3a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxc3a | dr11_v1_chr23_+_36144487_36144487 | -0.93 | 2.2e-04 | Click! |
| hoxa3a | dr11_v1_chr19_+_19756425_19756425 | -0.80 | 9.8e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_25777425 Show fit | 2.22 |
ENSDART00000021620
|
claudin d |
|
| chr18_-_40708537 Show fit | 1.87 |
ENSDART00000077577
|
si:ch211-132b12.8 |
|
| chr11_-_1550709 Show fit | 1.57 |
ENSDART00000110097
|
si:ch73-303b9.1 |
|
| chr10_-_21362071 Show fit | 1.49 |
ENSDART00000125167
|
avidin |
|
| chr10_-_21362320 Show fit | 1.47 |
ENSDART00000189789
|
avidin |
|
| chr24_+_1023839 Show fit | 1.32 |
ENSDART00000082526
|
zgc:111976 |
|
| chr6_+_28208973 Show fit | 1.25 |
ENSDART00000171216
ENSDART00000171377 ENSDART00000167389 ENSDART00000166988 |
si:ch73-14h10.2 |
|
| chr12_-_33357655 Show fit | 1.22 |
ENSDART00000066233
ENSDART00000148165 |
solute carrier family 16 (monocarboxylate transporter), member 3 |
|
| chr9_+_44994214 Show fit | 1.17 |
ENSDART00000141434
|
retinol saturase (all-trans-retinol 13,14-reductase) like |
|
| chr23_+_28322986 Show fit | 1.09 |
ENSDART00000134710
|
baculoviral IAP repeat containing 5b |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxa4a+hoxc3a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 1.8 | GO:0035803 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.0 | 1.7 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.4 | 1.3 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.0 | 1.2 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.0 | 1.2 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
| 0.4 | 1.1 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 0.1 | 1.0 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.1 | 1.0 | GO:0051445 | regulation of meiotic cell cycle(GO:0051445) |
| 0.3 | 0.9 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 2.1 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 2.0 | GO:0043186 | P granule(GO:0043186) |
| 0.1 | 1.5 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) |
| 0.0 | 1.1 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 1.1 | GO:0005901 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.3 | 1.0 | GO:0031310 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
| 0.0 | 0.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.7 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 0.7 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.0 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 1.9 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.1 | 1.8 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.4 | 1.5 | GO:0030228 | lipoprotein particle receptor activity(GO:0030228) |
| 0.3 | 1.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 1.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 1.2 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.1 | 1.1 | GO:0043028 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
| 0.0 | 1.0 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.2 | 0.9 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.9 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.6 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.6 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.4 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.4 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 0.4 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 0.9 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.9 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.8 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 0.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 0.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.4 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |