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PRJNA195909:zebrafish embryo and larva development

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Results for hoxa13a+hoxa13b

Z-value: 1.34

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Transcription factors associated with hoxa13a+hoxa13b

Gene Symbol Gene ID Gene Info
ENSDARG00000036254 homeobox A13b
ENSDARG00000100312 homeobox A13a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa13adr11_v1_chr19_+_19729506_19729506-0.235.5e-01Click!
hoxa13bdr11_v1_chr16_+_20895904_20895904-0.225.6e-01Click!

Activity profile of hoxa13a+hoxa13b motif

Sorted Z-values of hoxa13a+hoxa13b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_14191592 2.08 ENSDART00000164594
T-box transcription factor Ta
chr13_+_22675802 1.67 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr16_-_45917322 1.54 ENSDART00000060822
antifreeze protein type IV
chr23_+_39606108 1.32 ENSDART00000109464
G0/G1 switch 2
chr7_-_30367650 1.21 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr13_-_50614639 1.20 ENSDART00000170527
ventral expressed homeobox
chr19_-_24555623 1.19 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr22_+_25590391 1.00 ENSDART00000178133
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr14_-_21123551 0.89 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr7_-_69025306 0.86 ENSDART00000180796

chr19_-_24555935 0.86 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr10_-_24391030 0.84 ENSDART00000180013
ENSDART00000177914
solute carrier family 43 (amino acid system L transporter), member 2b
chr25_+_34641536 0.84 ENSDART00000167033

chr5_+_68807170 0.84 ENSDART00000017849
hairy and enhancer of split related-7
chr19_-_1948236 0.81 ENSDART00000163344
zinc and ring finger 2a
chr21_-_37733287 0.81 ENSDART00000157826
membrane protein, palmitoylated 1
chr14_+_34495216 0.77 ENSDART00000147756
wingless-type MMTV integration site family, member 8a
chr6_+_35362225 0.77 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr10_-_6427362 0.76 ENSDART00000166774
carbonic anhydrase IX
chr18_-_14677936 0.76 ENSDART00000111995
si:dkey-238o13.4
chr19_-_42291355 0.75 ENSDART00000150919
ENSDART00000151034
si:ch211-191i18.2
chr17_+_27456804 0.75 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr23_+_32499916 0.75 ENSDART00000134811
si:dkey-261h17.1
chr3_+_57948377 0.75 ENSDART00000047418
notum, palmitoleoyl-protein carboxylesterase a
chr3_-_37759969 0.72 ENSDART00000151105
ENSDART00000151208
si:dkey-260c8.6
chr24_+_9475809 0.72 ENSDART00000132688
si:ch211-285f17.1
chr23_+_7379728 0.72 ENSDART00000012194
GATA binding protein 5
chr4_-_61651223 0.69 ENSDART00000172688
si:dkey-26i24.1
chr18_+_26422124 0.67 ENSDART00000060245
cathepsin H
chr13_+_30804367 0.67 ENSDART00000053946
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr24_-_8732519 0.65 ENSDART00000082351
transcription factor AP-2 alpha
chr5_-_41307550 0.65 ENSDART00000143446
natriuretic peptide receptor 3
chr8_-_19280856 0.63 ENSDART00000100473
zgc:77486
chr25_-_31739309 0.63 ENSDART00000098896
acyl-CoA thioesterase 19
chr25_+_24616717 0.62 ENSDART00000089113
ankyrin repeat and BTB (POZ) domain containing 2b
chr10_-_6454386 0.61 ENSDART00000168549
carbonic anhydrase IX
chr7_+_67429185 0.61 ENSDART00000162553
ENSDART00000178646
lysyl-tRNA synthetase
chr7_-_16562200 0.61 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr13_+_28495983 0.60 ENSDART00000144968
fibroblast growth factor 8a
chr9_-_53666031 0.60 ENSDART00000126314
protocadherin 8
chr21_-_34844316 0.60 ENSDART00000029708
zgc:56585
chr3_-_48259289 0.59 ENSDART00000160717
zinc finger protein 750
chr5_-_36328688 0.59 ENSDART00000011399
ephrin-B1
chr15_+_14856307 0.59 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr14_+_34490445 0.58 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr21_-_20328375 0.58 ENSDART00000079593
solute carrier family 26 (anion exchanger), member 1
chr15_-_21132480 0.58 ENSDART00000078734
ENSDART00000157481
alpha-2-macroglobulin-like
chr8_-_44298964 0.58 ENSDART00000098520
frizzled class receptor 10
chr21_-_25748913 0.57 ENSDART00000134217

chr24_+_5237753 0.57 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr21_+_13301798 0.56 ENSDART00000140206
adenosine A2a receptor b
chr4_+_52356485 0.56 ENSDART00000170639
zgc:173705
chr23_-_21446985 0.56 ENSDART00000044080
hairy-related 12
chr4_+_29165840 0.55 ENSDART00000169539

chr3_-_39488482 0.55 ENSDART00000135192
zgc:100868
chr16_+_42830152 0.54 ENSDART00000159730
polymerase (RNA) III (DNA directed) polypeptide G like b
chr8_+_32755688 0.54 ENSDART00000137897
hemicentin 2
chr14_+_26437891 0.54 ENSDART00000175459
G protein-coupled receptor 137
chr2_+_31838442 0.53 ENSDART00000066789
STARD3 N-terminal like
chr17_-_44249538 0.53 ENSDART00000008816
orthodenticle homeobox 2b
chr3_+_24134418 0.53 ENSDART00000156204
si:ch211-246i5.5
chr12_+_27536095 0.53 ENSDART00000013033
ets variant 4
chr3_-_39488639 0.52 ENSDART00000161644
zgc:100868
chr4_+_5506952 0.52 ENSDART00000032857
ENSDART00000160222
mitogen-activated protein kinase 11
chr3_+_62161184 0.52 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr1_-_15329277 0.52 ENSDART00000109970
DLC1 Rho GTPase activating protein
chr13_+_17694845 0.52 ENSDART00000079778
interferon-induced protein with tetratricopeptide repeats 8
chr25_+_13620555 0.51 ENSDART00000163642
si:ch211-172l8.4
chr2_+_47905735 0.50 ENSDART00000159701
finTRIM family, member 23
chr25_-_31423493 0.50 ENSDART00000027661
myogenic differentiation 1
chr13_-_11986754 0.49 ENSDART00000164214
nucleophosmin/nucleoplasmin, 3
chr4_-_43280244 0.49 ENSDART00000150762
si:dkeyp-53e4.1
chr15_-_5901514 0.49 ENSDART00000155252
si:ch73-281n10.2
chr15_+_42431198 0.49 ENSDART00000189951
ENSDART00000089694
T cell lymphoma invasion and metastasis 1b
chr4_+_37406676 0.49 ENSDART00000130981
si:ch73-134f24.1
chr2_+_16781015 0.49 ENSDART00000155147
ENSDART00000003845
transferrin-a
chr6_-_53426773 0.48 ENSDART00000162791
macrophage stimulating 1
chr1_-_35924495 0.48 ENSDART00000184424
SMAD family member 1
chr13_+_7442023 0.48 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr15_+_28685892 0.48 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr12_+_27537357 0.47 ENSDART00000136212
ets variant 4
chr18_+_34599315 0.47 ENSDART00000159306
ENSDART00000088675
TCDD-inducible poly(ADP-ribose) polymerase
chr17_-_32621103 0.47 ENSDART00000155321
XK related 5b
chr20_-_34127415 0.47 ENSDART00000010028
prostaglandin-endoperoxide synthase 2b
chr16_-_46573211 0.47 ENSDART00000193392
zgc:174938
chr14_+_34966598 0.46 ENSDART00000004550
ring finger protein 145a
chr24_-_33756003 0.46 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr21_+_11503212 0.46 ENSDART00000146701
si:dkey-184p9.7
chr12_+_25600685 0.46 ENSDART00000077157
SIX homeobox 3b
chr1_+_47486104 0.46 ENSDART00000114746
leucine rich repeat containing 58a
chr12_+_19356623 0.46 ENSDART00000078284
DNA meiotic recombinase 1
chr7_-_24364536 0.45 ENSDART00000064789
thioredoxin
chr11_+_7580079 0.45 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr2_+_16780643 0.45 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
transferrin-a
chr22_+_18188045 0.45 ENSDART00000140106
myocyte enhancer factor 2b
chr17_-_23412705 0.44 ENSDART00000126995
si:ch211-149k12.3
chr10_-_10864331 0.44 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr9_+_45839260 0.44 ENSDART00000114814
twist2
chr4_-_70488123 0.43 ENSDART00000169266
si:dkeyp-44b5.5
chr7_-_26076970 0.43 ENSDART00000101120
zgc:92664
chr6_-_45869127 0.43 ENSDART00000062459
ENSDART00000180563
RNA binding motif protein 19
chr16_-_15387459 0.43 ENSDART00000053754
hyaluronan synthase 2
chr5_-_30715225 0.43 ENSDART00000016758
finTRIM family, member 82
chr18_+_31073265 0.43 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr9_+_38158570 0.43 ENSDART00000059549
ENSDART00000133060
nucleolar protein interacting with the FHA domain of MKI67
chr6_+_16468776 0.43 ENSDART00000109151
ENSDART00000114667
zgc:161969
chr2_-_44283554 0.43 ENSDART00000184684
myelin protein zero
chr2_-_30659222 0.42 ENSDART00000145405
catenin (cadherin-associated protein), delta 2b
chr13_+_28675686 0.42 ENSDART00000027213
internexin neuronal intermediate filament protein, alpha a
chr2_-_59145027 0.42 ENSDART00000128320

chr4_+_37239915 0.42 ENSDART00000146015
zinc finger protein 973
chr13_+_22295905 0.42 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr9_+_32301017 0.42 ENSDART00000127916
ENSDART00000183298
ENSDART00000143103
heat shock 10 protein 1
chr22_+_18187857 0.42 ENSDART00000166300
myocyte enhancer factor 2b
chr7_+_49664174 0.42 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr5_-_33281046 0.41 ENSDART00000051344
ENSDART00000138116
surfeit 6
chr4_-_5652030 0.41 ENSDART00000010903
radial spoke head 9 homolog
chr6_+_58915889 0.41 ENSDART00000083628
DNA-damage-inducible transcript 3
chr16_+_42829735 0.40 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr21_-_22543611 0.40 ENSDART00000177084
myosin VB
chr3_+_31093455 0.40 ENSDART00000153074
si:dkey-66i24.9
chr2_-_30055432 0.40 ENSDART00000056747
sonic hedgehog b
chr15_+_46313082 0.40 ENSDART00000153830
si:ch1073-190k2.1
chr8_+_14381272 0.39 ENSDART00000057642
acyl-CoA binding domain containing 6
chr8_-_13985032 0.39 ENSDART00000140576
insulin-like growth factor 3
chr13_+_29519115 0.39 ENSDART00000086711
carbohydrate (chondroitin 6) sulfotransferase 3a
chr2_+_19195841 0.39 ENSDART00000163137
ENSDART00000161095
ELOVL fatty acid elongase 1a
chr15_+_11814969 0.39 ENSDART00000127248

chr10_-_7988396 0.39 ENSDART00000141445
ENSDART00000024282
EWS RNA-binding protein 1a
chr3_+_24275766 0.38 ENSDART00000055607
platelet-derived growth factor beta polypeptide b
chr16_+_29509133 0.38 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr21_-_2310064 0.38 ENSDART00000169520
si:ch211-241b2.1
chr10_-_5016997 0.38 ENSDART00000101414
heterogeneous nuclear ribonucleoprotein D
chr4_-_56898328 0.38 ENSDART00000169189
si:dkey-269o24.6
chr17_+_21295132 0.38 ENSDART00000103845
enolase family member 4
chr5_-_36948586 0.38 ENSDART00000193606
H3 histone, family 3C
chr4_-_37707809 0.37 ENSDART00000162606
zinc finger protein 1139
chr11_+_30310170 0.37 ENSDART00000127797
UDP glucuronosyltransferase 1 family, polypeptide B3
chr20_-_29499363 0.37 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr12_+_19199735 0.37 ENSDART00000066393
pdgfa associated protein 1a
chr4_+_73672430 0.37 ENSDART00000174310
ENSDART00000150505
si:dkey-262g12.7
chr8_-_19216180 0.37 ENSDART00000146162
si:ch73-222f22.2
chr22_-_4644484 0.36 ENSDART00000167748
fibrillin 2b
chr1_+_54683655 0.36 ENSDART00000132785
lysine-rich nucleolar protein 1
chr11_-_36279602 0.36 ENSDART00000122531
ENSDART00000103064
ENSDART00000125616
nuclear transcription factor Y, alpha
chr23_+_19813677 0.36 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr5_-_13685047 0.36 ENSDART00000018351
zgc:65851
chr5_+_6955900 0.36 ENSDART00000099417

chr14_+_15495088 0.36 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
chr23_+_43718115 0.36 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr6_+_43015916 0.36 ENSDART00000064888
T cell leukemia translocation altered
chr4_-_45301719 0.35 ENSDART00000150282
si:ch211-162i8.2
chr20_-_14012859 0.35 ENSDART00000152429
si:ch211-22i13.2
chr4_+_63818212 0.35 ENSDART00000164929
si:dkey-30f3.2
chr5_-_40510397 0.35 ENSDART00000146237
ENSDART00000051065
follistatin a
chr7_-_6680622 0.35 ENSDART00000180437
ENSDART00000173270
ENSDART00000066450
dual specificity phosphatase 19b
chr8_+_30709685 0.35 ENSDART00000133989
ureidopropionase, beta
chr1_+_5402476 0.34 ENSDART00000040204
tubulin, alpha 8 like 2
chr4_+_45610254 0.34 ENSDART00000150866
zinc finger protein 1038
chr9_+_17306162 0.34 ENSDART00000075926
sciellin
chr21_+_25236297 0.34 ENSDART00000112783
transmembrane protein 45B
chr8_-_19216657 0.34 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
chr2_+_49569017 0.34 ENSDART00000109471
semaphorin 4e
chr2_-_30135446 0.33 ENSDART00000141906
transient receptor potential cation channel, subfamily A, member 1a
chr19_-_47571456 0.33 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr16_-_7793457 0.33 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr18_+_20034023 0.33 ENSDART00000139441
mortality factor 4 like 1
chr21_+_30351256 0.33 ENSDART00000078341
forkhead box I3a
chr8_+_30671060 0.33 ENSDART00000193749
adenosine A2a receptor a
chr6_+_7977611 0.33 ENSDART00000112290
paralemmin 3
chr21_-_25756119 0.33 ENSDART00000002341
claudin c
chr7_-_45999333 0.33 ENSDART00000158603
si:ch211-260e23.8
chr22_-_622937 0.33 ENSDART00000145685
ENSDART00000144309
serine/arginine-rich splicing factor 3b
chr6_-_57485411 0.33 ENSDART00000011663
small nuclear ribonucleoprotein polypeptides B and B1
chr4_-_52621665 0.33 ENSDART00000137064
si:dkeyp-104f11.6
chr4_+_13452907 0.33 ENSDART00000186116
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr9_+_32301456 0.33 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
heat shock 10 protein 1
chr9_-_32300783 0.32 ENSDART00000078596
heat shock 60 protein 1
chr8_-_25002182 0.32 ENSDART00000078792
adenosylhomocysteinase-like 1
chr2_-_24962820 0.31 ENSDART00000182767
helicase-like transcription factor
chr19_+_42469058 0.31 ENSDART00000076915
si:dkey-166k12.1
chr18_-_8380090 0.31 ENSDART00000141581
ENSDART00000081143
selenophosphate synthetase 1
chr4_+_45148652 0.31 ENSDART00000150798
si:dkey-51d8.9
chr1_-_26664840 0.31 ENSDART00000102500
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr13_-_37619159 0.30 ENSDART00000186348
zgc:152791
chr20_+_32501748 0.30 ENSDART00000152944
ENSDART00000021035
SEC63 homolog, protein translocation regulator
chr23_-_43718067 0.30 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr18_-_35407695 0.30 ENSDART00000191845
ENSDART00000141703
small nuclear ribonucleoprotein polypeptide A
chr8_+_32747612 0.30 ENSDART00000142824
hemicentin 2
chr22_+_465269 0.30 ENSDART00000145767
cadherin, EGF LAG seven-pass G-type receptor 2
chr1_+_14466860 0.30 ENSDART00000114097
tromal interaction molecule 2a
chr15_+_28685625 0.30 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr4_-_35899188 0.30 ENSDART00000167093
zgc:174653
chr21_-_11970199 0.29 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr8_-_13641022 0.29 ENSDART00000080875
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr17_-_49481672 0.29 ENSDART00000166394
FCF1 rRNA-processing protein
chr8_+_14886452 0.29 ENSDART00000146589
sterol O-acyltransferase 1
chr5_+_32845759 0.29 ENSDART00000136552
si:ch211-208h16.4
chr18_+_38885309 0.29 ENSDART00000041597
cAMP-regulated phosphoprotein 19a
chr4_-_30440116 0.29 ENSDART00000159935
si:dkey-199m13.5

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa13a+hoxa13b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.5 1.4 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.3 1.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.3 1.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.7 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.2 0.7 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 0.7 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.5 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.2 0.6 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.2 0.6 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.1 0.4 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.1 0.6 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.8 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.5 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.8 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.6 GO:1990402 embryonic liver development(GO:1990402)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:0042148 strand invasion(GO:0042148)
0.1 0.4 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.4 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 1.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.4 GO:0050955 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.1 3.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.2 GO:0065001 specification of axis polarity(GO:0065001)
0.1 1.5 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.4 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.2 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.3 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.3 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.2 GO:0046824 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.5 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.6 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 1.7 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.5 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.2 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.2 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.3 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.1 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.3 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060923 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.2 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.6 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.3 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.1 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.4 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.5 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.1 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0046323 glucose import(GO:0046323)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.1 GO:0006833 water transport(GO:0006833)
0.0 0.3 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.1 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.3 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.0 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:0046849 bone remodeling(GO:0046849)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.0 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.0 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097189 apoptotic body(GO:0097189)
0.1 3.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0005883 neurofilament(GO:0005883)
0.1 0.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.2 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.7 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 0.5 GO:0000150 recombinase activity(GO:0000150)
0.1 0.9 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 1.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.0 0.2 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0017050 ceramide kinase activity(GO:0001729) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0034632 retinol transporter activity(GO:0034632)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor