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PRJNA195909:zebrafish embryo and larva development

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Results for hnf4g

Z-value: 1.58

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Transcription factors associated with hnf4g

Gene Symbol Gene ID Gene Info
ENSDARG00000071565 hepatocyte nuclear factor 4, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf4gdr11_v1_chr24_-_23671709_23671709-0.791.2e-02Click!

Activity profile of hnf4g motif

Sorted Z-values of hnf4g motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_2590222 5.59 ENSDART00000185711

chr17_-_2573021 4.60 ENSDART00000074181
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2578026 4.48 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr4_-_77114795 4.33 ENSDART00000144849

chr17_-_2595736 4.07 ENSDART00000128797
zona pellucida glycoprotein 3, tandem duplicate 2
chr10_+_19569052 4.05 ENSDART00000058425

chr17_-_2584423 3.91 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr9_+_8380728 3.51 ENSDART00000133501
si:ch1073-75o15.4
chr22_-_24992532 3.10 ENSDART00000102751
si:dkey-179j5.5
chr8_-_49207319 2.69 ENSDART00000022870
family with sequence similarity 110, member A
chr7_-_24520866 1.95 ENSDART00000077039
fatty acid amide hydrolase 2b
chr2_+_37897079 1.89 ENSDART00000141784
telomerase-associated protein 1
chr23_+_19790962 1.87 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr22_-_24818066 1.78 ENSDART00000143443
vitellogenin 6
chr1_-_9485939 1.78 ENSDART00000157814
mical-like 2b
chr11_+_11152214 1.60 ENSDART00000148030
lymphocyte antigen 75
chr21_-_43428040 1.58 ENSDART00000148325
serine/threonine protein kinase 26
chr17_+_50701748 1.49 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr23_+_2740741 1.42 ENSDART00000134938
zgc:114123
chr11_-_18017287 1.42 ENSDART00000155443
glutamine-rich 1
chr14_-_16810401 1.38 ENSDART00000158396
ENSDART00000170758
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr11_-_27827442 1.38 ENSDART00000121847
ENSDART00000132018
ENSDART00000145744
ENSDART00000134677
ENSDART00000130800
cleavage stimulation factor, 3' pre-RNA, subunit 1
chr5_-_30080332 1.36 ENSDART00000140049
beta-carotene oxygenase 2a
chr16_+_26846495 1.35 ENSDART00000078124
tripartite motif containing 35-29
chr22_-_24738188 1.27 ENSDART00000050238
vitellogenin 1
chr14_+_989733 1.19 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr7_-_59514547 1.18 ENSDART00000168457
SLX1 homolog B, structure-specific endonuclease subunit
chr23_+_44461493 1.15 ENSDART00000149854
si:ch1073-228j22.1
chr5_-_69180227 1.14 ENSDART00000154816
zgc:171967
chr16_+_48460873 1.13 ENSDART00000159902
exostosin glycosyltransferase 1a
chr5_-_69180587 1.12 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr6_-_12296170 1.07 ENSDART00000155685
plakophilin 4
chr25_-_24240797 1.05 ENSDART00000132790
SPT2 chromatin protein domain containing 1
chr23_-_43595956 1.05 ENSDART00000162186
itchy E3 ubiquitin protein ligase b
chr7_+_39738505 1.05 ENSDART00000004365
transcriptional adaptor 2B
chr13_-_35908275 1.04 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr7_+_24520518 1.01 ENSDART00000173604
bloodthirsty-related gene family, member 9
chr15_+_21882419 0.99 ENSDART00000157216
si:dkey-103g5.4
chr6_-_46474483 0.99 ENSDART00000155761
retinol dehydrogenase 20
chr15_-_30857350 0.98 ENSDART00000138988
A kinase (PRKA) anchor protein 1b
chr5_-_36597612 0.97 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr21_-_11054876 0.96 ENSDART00000146576
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_31682135 0.95 ENSDART00000153988
cache domain containing 1
chr11_+_25157374 0.94 ENSDART00000019450
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr11_+_19068442 0.90 ENSDART00000171766
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr19_-_1002959 0.90 ENSDART00000168138
euchromatic histone-lysine N-methyltransferase 2
chr1_+_41690402 0.85 ENSDART00000177298
F-box protein 41
chr21_-_27273147 0.82 ENSDART00000143239
MAP/microtubule affinity-regulating kinase 2a
chr13_-_35907768 0.82 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr7_-_20611039 0.80 ENSDART00000170422
si:dkey-19b23.8
chr8_+_39802506 0.80 ENSDART00000018862
HNF1 homeobox a
chr21_-_27272657 0.80 ENSDART00000040754
ENSDART00000175009
MAP/microtubule affinity-regulating kinase 2a
chr12_-_10567188 0.79 ENSDART00000144283
myoferlin
chr15_+_34069746 0.77 ENSDART00000163513
ADP-ribosylation factor-like 4aa
chr2_-_10877765 0.77 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr14_-_470505 0.75 ENSDART00000067147
ankyrin repeat domain 50
chr7_+_24496894 0.75 ENSDART00000149994
negative elongation factor complex member A
chr22_+_1300587 0.73 ENSDART00000124161
si:ch73-138e16.5
chr1_-_12064715 0.72 ENSDART00000143628
ENSDART00000103406
phospholipase A2, group XIIA
chr8_-_1264893 0.71 ENSDART00000190371
cell division cycle 14B
chr22_-_31517300 0.70 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr7_-_39738460 0.65 ENSDART00000052201
coiled-coil domain containing 96
chr5_+_25681174 0.64 ENSDART00000134773
zinc finger, AN1-type domain 5a
chr7_+_24951552 0.64 ENSDART00000173644
MAP/microtubule affinity-regulating kinase 2b
chr15_-_25153352 0.59 ENSDART00000078095
ENSDART00000122184
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr12_-_33706726 0.59 ENSDART00000153135
myosin XVB
chr15_-_18218227 0.57 ENSDART00000156332
bloodthirsty-related gene family, member 21
chr21_-_43474012 0.55 ENSDART00000065104
transmembrane protein 185
chr2_+_11670270 0.53 ENSDART00000100524
finTRIM family, member 1
chr10_-_21953643 0.52 ENSDART00000188921
ENSDART00000193569

chr17_-_6076266 0.51 ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr7_+_29115890 0.50 ENSDART00000052345
tnfrsf1a-associated via death domain
chr4_-_170120 0.50 ENSDART00000171333
epidermal growth factor receptor pathway substrate 8
chr1_-_59169815 0.49 ENSDART00000100163
wu:fk65c09
chr14_-_25078569 0.43 ENSDART00000172802
ENSDART00000173345
ENSDART00000135004
matrin 3-like 1.1
chr15_-_41700406 0.41 ENSDART00000181460
si:ch211-276c2.4
chr5_-_62317496 0.41 ENSDART00000180089
zgc:85789
chr8_-_20838342 0.40 ENSDART00000141345
si:ch211-133l5.7
chr13_+_18520738 0.39 ENSDART00000113952
toll-like receptor 4a, like
chr1_-_57129179 0.38 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
chr21_-_11856143 0.38 ENSDART00000151204
ubiquitin-conjugating enzyme E2R 2
chr25_+_29472361 0.37 ENSDART00000154857
interleukin 17 receptor E-like
chr8_+_53464216 0.36 ENSDART00000169514
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr18_+_16330025 0.36 ENSDART00000142353
neurotensin
chr13_+_26703922 0.36 ENSDART00000020946
Fanconi anemia, complementation group L
chr6_-_9251122 0.35 ENSDART00000167835

chr12_+_33916939 0.35 ENSDART00000149292
tripartite motif containing 8b
chr15_+_3825117 0.34 ENSDART00000183315

chr15_+_8192715 0.34 ENSDART00000156442
ENSDART00000077660
mitochondrial intermediate peptidase
chr8_+_23390844 0.33 ENSDART00000184556
si:dkey-16n15.6
chr12_+_22607761 0.32 ENSDART00000153112
si:dkey-219e21.2
chr9_+_29616854 0.32 ENSDART00000033902
ENSDART00000143493
PHD finger protein 11
chr2_-_42173834 0.29 ENSDART00000098357
ENSDART00000144707
solute carrier family 39 (zinc transporter), member 6
chr13_-_303137 0.27 ENSDART00000099131
chitin synthase 1
chr20_+_29436601 0.26 ENSDART00000136804
formin 1
chr19_-_22387141 0.24 ENSDART00000151234
epiplakin 1
chr22_+_2844865 0.24 ENSDART00000139123
si:dkey-20i20.4
chr3_-_8765165 0.24 ENSDART00000191131

chr15_+_864761 0.21 ENSDART00000174813
ENSDART00000192053
si:dkey-7i4.12
si:dkey-7i4.10
chr3_-_27868183 0.21 ENSDART00000185812
4-aminobutyrate aminotransferase
chr10_+_41765944 0.21 ENSDART00000171484
ring finger protein 34b
chr22_-_20376488 0.20 ENSDART00000140187
zinc finger and BTB domain containing 7a
chr17_-_6076084 0.20 ENSDART00000058890
epoxide hydrolase 2, cytoplasmic
chr17_+_20174044 0.19 ENSDART00000156028
si:ch211-248a14.8
chr10_-_24753715 0.19 ENSDART00000192401
integrin-linked kinase
chr7_-_26518086 0.18 ENSDART00000058913
eukaryotic translation initiation factor 4A1A
chr8_-_22157301 0.17 ENSDART00000158383
nephronophthisis 4
chr3_-_36440705 0.13 ENSDART00000162875
rogdi homolog (Drosophila)
chr10_+_45128375 0.12 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr1_-_57172294 0.12 ENSDART00000063774
Rac family small GTPase 1, like
chr9_+_38163876 0.09 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr6_-_10788065 0.09 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr25_+_8316953 0.09 ENSDART00000154598
mucin 2.2, oligomeric mucus/gel-forming
chr4_-_72468168 0.09 ENSDART00000182995
ENSDART00000174067

chr13_+_32807419 0.08 ENSDART00000085252
PQ loop repeat containing 3
chr1_+_15226268 0.07 ENSDART00000109911
heparan-alpha-glucosaminide N-acetyltransferase
chr15_+_29728377 0.06 ENSDART00000099958
zgc:153372
chr11_+_12860260 0.05 ENSDART00000190410
zinc finger, CCCH-type with G patch domain
chr23_-_40776046 0.05 ENSDART00000136230
si:dkeyp-27c8.1
chr19_+_10536093 0.04 ENSDART00000138706
si:dkey-211g8.1
chr7_-_29115772 0.04 ENSDART00000076386
F-box and leucine-rich repeat protein 8
chr6_+_11026866 0.01 ENSDART00000189619
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4g

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 17.1 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.4 1.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 1.4 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 1.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.9 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 1.0 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.1 1.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.4 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 3.1 GO:0032355 response to estradiol(GO:0032355)
0.1 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.8 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.3 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.2 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.2 GO:0003211 cardiac ventricle formation(GO:0003211)
0.0 1.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 1.8 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 1.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.7 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.1 0.8 GO:0032021 NELF complex(GO:0032021)
0.1 1.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.0 GO:0070461 SAGA-type complex(GO:0070461)
0.0 16.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 17.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.4 3.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 1.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 1.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 0.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.4 GO:0051117 ATPase binding(GO:0051117)
0.1 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 1.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 5.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.9 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation