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PRJNA195909:zebrafish embryo and larva development

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Results for hinfp

Z-value: 1.60

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Transcription factors associated with hinfp

Gene Symbol Gene ID Gene Info
ENSDARG00000004851 histone H4 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hinfpdr11_v1_chr5_+_30596477_305964770.881.9e-03Click!

Activity profile of hinfp motif

Sorted Z-values of hinfp motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_6010177 4.29 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr9_+_8408054 3.19 ENSDART00000144373
zgc:153499
chr10_-_21362320 2.94 ENSDART00000189789
avidin
chr10_-_21362071 2.91 ENSDART00000125167
avidin
chr19_+_8612839 2.69 ENSDART00000144925
sorting nexin family member 27a
chr13_+_28618086 2.48 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr8_+_11687254 2.42 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr4_-_20081621 2.40 ENSDART00000024647
DENN/MADD domain containing 6B
chr5_-_63065912 2.38 ENSDART00000161149
family with sequence similarity 57 member A
chr9_+_8407778 2.38 ENSDART00000102754
ENSDART00000178144
zgc:153499
chr23_+_43668756 2.37 ENSDART00000112598
OTU deubiquitinase 4
chr8_+_11687586 2.30 ENSDART00000146241
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr16_-_27564256 2.21 ENSDART00000078297
zgc:153215
chr24_+_5799764 2.12 ENSDART00000154482
si:ch211-157j23.2
chr23_+_45845423 2.05 ENSDART00000183404
lamin L3
chr11_+_6009984 1.96 ENSDART00000185680
GTP binding protein 3, mitochondrial
chr11_+_2710530 1.71 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr2_-_56635744 1.67 ENSDART00000167790
ENSDART00000168160
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr5_+_47862636 1.65 ENSDART00000139824
RAS p21 protein activator (GTPase activating protein) 1a
chr25_-_21763750 1.65 ENSDART00000089596
transmembrane protein 168b
chr5_+_47863153 1.63 ENSDART00000051518
RAS p21 protein activator (GTPase activating protein) 1a
chr4_+_11690923 1.62 ENSDART00000150624
muskelin 1, intracellular mediator containing kelch motifs
chr11_-_25853212 1.60 ENSDART00000145655
transmembrane protein 51b
chr5_-_37881345 1.53 ENSDART00000084819
Rho GTPase activating protein 35b
chr7_-_48396193 1.51 ENSDART00000083555
SIN3 transcription regulator family member Ab
chr19_-_31765615 1.49 ENSDART00000103636
si:dkeyp-120h9.1
chr3_-_8399774 1.49 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
RNA binding fox-1 homolog 3b
chr4_-_2196798 1.43 ENSDART00000110178
ENSDART00000149330
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr7_-_69184420 1.40 ENSDART00000168311
ENSDART00000159239
ENSDART00000161319
ubiquitin specific peptidase 10
chr5_-_47975440 1.38 ENSDART00000145665
ENSDART00000007057
cyclin H
chr20_+_42246948 1.37 ENSDART00000061135
golgi-associated PDZ and coiled-coil motif containing
chr13_+_29925397 1.24 ENSDART00000123482
CUE domain containing 2
chr2_+_27651984 1.19 ENSDART00000126762
transmembrane protein 68
chr16_+_40954481 1.12 ENSDART00000058587
glycogen synthase kinase binding protein
chr21_+_21279159 1.12 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr3_-_21185016 1.10 ENSDART00000155550
TAO kinase 2a
chr16_+_23495600 1.06 ENSDART00000021092
sorting nexin family member 27b
chr4_-_20232974 1.03 ENSDART00000193353
serine/threonine kinase 38 like
chr20_-_43917647 1.03 ENSDART00000026213
MAP/microtubule affinity-regulating kinase 3b
chr5_-_18961694 1.01 ENSDART00000142531
ENSDART00000090521
ankyrin repeat and LEM domain containing 2
chr20_+_35208020 1.00 ENSDART00000153315
ENSDART00000045135
F-box protein 16
chr6_+_34038963 0.99 ENSDART00000057732
ENSDART00000192496
adaptor-related protein complex 1, mu 3 subunit
chr17_+_6793001 0.98 ENSDART00000030773
forkhead box O3A
chr16_-_17586883 0.96 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr6_-_9565526 0.93 ENSDART00000151470
mitogen-activated protein kinase kinase kinase 2
chr2_-_27651674 0.93 ENSDART00000177402
trimethylguanosine synthase 1
chr16_+_27564270 0.92 ENSDART00000140460
transmembrane protein 67
chr7_-_8961941 0.91 ENSDART00000111002
si:ch211-74f19.2
chr16_+_9726038 0.89 ENSDART00000192988
ENSDART00000020859
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr3_-_44012748 0.86 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
interleukin 4 receptor, tandem duplicate 1
chr15_-_25319663 0.86 ENSDART00000042218
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a
chr19_-_31900893 0.85 ENSDART00000113797
zinc finger and BTB domain containing 10
chr7_+_29163762 0.84 ENSDART00000173762
solute carrier family 38, member 8b
chr16_+_2905150 0.82 ENSDART00000109980
leucyl-tRNA synthetase 2, mitochondrial
chr7_+_9880811 0.81 ENSDART00000128376
lines homolog 1
chr1_+_54069450 0.79 ENSDART00000108601
ENSDART00000187878
DDB1 and CUL4 associated factor 15
chr2_+_15048410 0.79 ENSDART00000058484
calponin 3, acidic b
chr24_+_28383278 0.77 ENSDART00000018095
SH3-domain GRB2-like endophilin B1a
chr12_-_290413 0.77 ENSDART00000152496
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr5_-_56943064 0.77 ENSDART00000146991
si:ch211-127d4.3
chr3_+_25849560 0.74 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr1_+_57347888 0.73 ENSDART00000104222
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr21_-_12749501 0.73 ENSDART00000179724

chr7_+_23495986 0.72 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr7_-_65114067 0.70 ENSDART00000110614
ENSDART00000098277
transmembrane protein 41B
chr25_-_10791437 0.67 ENSDART00000127054

chr10_+_21444654 0.64 ENSDART00000140113
ENSDART00000184386
ENSDART00000019252
F-box and WD repeat domain containing 11b
chr23_+_1216215 0.64 ENSDART00000165957
utrophin
chr2_+_27652386 0.64 ENSDART00000188261
transmembrane protein 68
chr23_+_30707837 0.62 ENSDART00000016096
DnaJ (Hsp40) homolog, subfamily C, member 11a
chr19_-_1023051 0.61 ENSDART00000158429
transmembrane protein 42b
chr8_-_49935358 0.60 ENSDART00000159782
ENSDART00000156841
ATP/GTP binding protein 1

chr20_-_2298970 0.54 ENSDART00000136067
si:ch73-18b11.1
chr14_+_52440161 0.54 ENSDART00000168437
DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like
chr17_+_53297822 0.53 ENSDART00000168297
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr8_+_21225064 0.53 ENSDART00000129210
cryptochrome circadian clock 1ba
chr6_-_58975010 0.52 ENSDART00000144911
ENSDART00000144514
methionyl-tRNA synthetase
chr19_+_5135113 0.50 ENSDART00000151310
si:dkey-89b17.4
chr14_-_16423200 0.49 ENSDART00000108868
ENSDART00000161793
mastermind-like transcriptional coactivator 1
chr25_-_31907590 0.49 ENSDART00000149707
ENSDART00000149471
eukaryotic translation initiation factor 3, subunit Ja
chr8_+_41533268 0.48 ENSDART00000142377
si:ch211-158d24.2
chr3_+_26035550 0.46 ENSDART00000078137
ankyrin repeat domain 54
chr23_-_45319592 0.44 ENSDART00000189861
coiled-coil domain containing 171
chr20_+_28266892 0.44 ENSDART00000103330
ChaC, cation transport regulator homolog 1 (E. coli)
chr19_-_11425542 0.41 ENSDART00000177875
ENSDART00000080762
septin 7a
chr10_-_35321625 0.41 ENSDART00000131268
rhomboid domain containing 2
chr21_+_18950575 0.41 ENSDART00000036172
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr1_-_40132831 0.40 ENSDART00000135647
si:ch211-113e8.10
chr7_-_39611109 0.40 ENSDART00000149991
protein tyrosine phosphatase, receptor type, J a
chr3_+_60962410 0.37 ENSDART00000042674
helicase with zinc finger
chr10_+_13279079 0.36 ENSDART00000135082
transmembrane protein 267
chr24_+_17345521 0.36 ENSDART00000024722
ENSDART00000154250
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr2_+_16173999 0.36 ENSDART00000177639
ENSDART00000157601
ENSDART00000190186
ENSDART00000045933
SH3-domain GRB2-like endophilin B1b
chr2_-_5074812 0.35 ENSDART00000163728
discs, large (Drosophila) homolog 1, like
chr8_+_36983559 0.34 ENSDART00000127053
lysine (K)-specific demethylase 5C
chr21_-_3770636 0.34 ENSDART00000053596
secretory carrier membrane protein 1
chr10_+_8551897 0.33 ENSDART00000084353
TBC1 domain family, member 10Ab
chr3_-_44059902 0.32 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr11_+_1551603 0.30 ENSDART00000185383
ENSDART00000121489
ENSDART00000040577
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr4_+_72580821 0.26 ENSDART00000124528
si:cabz01054394.5
chr5_+_27429872 0.25 ENSDART00000087894
zgc:165555
chr20_-_2725594 0.24 ENSDART00000152120
akirin 2
chr22_+_31059919 0.22 ENSDART00000077063
SEC13 homolog, nuclear pore and COPII coat complex component
chr5_+_31168096 0.20 ENSDART00000086443
ENSDART00000192271
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr22_+_569565 0.18 ENSDART00000037069
ubiquitin specific peptidase 49
chr16_+_42477155 0.17 ENSDART00000154798
si:ch211-135n15.1
chr21_+_28747236 0.14 ENSDART00000137874
zgc:100829
chr6_+_7553085 0.13 ENSDART00000150939
ENSDART00000151114
myosin, heavy chain 10, non-muscle
chr7_-_29231686 0.13 ENSDART00000173780
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr6_-_35310224 0.12 ENSDART00000148997
nitric oxide synthase 1 (neuronal) adaptor protein a
chr22_-_24900121 0.12 ENSDART00000147643
si:dkey-4c23.3
chr7_+_568819 0.12 ENSDART00000173716
neurexin 2b
chr5_-_8483457 0.09 ENSDART00000171886
ENSDART00000159477
ENSDART00000157423
leukemia inhibitory factor receptor alpha a
chr7_-_62244744 0.09 ENSDART00000192522
ENSDART00000170635
ENSDART00000073872
cholecystokinin A receptor
chr8_+_49936585 0.06 ENSDART00000098707
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr21_+_28747069 0.05 ENSDART00000014058
zgc:100829
chr24_-_1023112 0.05 ENSDART00000147508
ENSDART00000066863
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr11_-_21363834 0.04 ENSDART00000080051
si:dkey-85p17.3
chr2_-_1468258 0.03 ENSDART00000114431
glycosylphosphatidylinositol anchor attachment 1
chr16_+_9053275 0.03 ENSDART00000123150
dynein, axonemal, heavy chain 5
chr23_+_1078072 0.01 ENSDART00000159263
ENSDART00000053527
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of hinfp

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 1.4 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.3 1.5 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.3 1.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.3 6.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 1.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 2.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 3.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 3.3 GO:0048013 negative regulation of Ras protein signal transduction(GO:0046580) ephrin receptor signaling pathway(GO:0048013)
0.1 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.4 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.1 1.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 3.8 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.4 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.1 GO:0044321 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.4 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.9 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.6 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.4 GO:0051260 protein homooligomerization(GO:0051260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.2 4.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 1.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 3.7 GO:0005769 early endosome(GO:0005769)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:0009374 biotin binding(GO:0009374)
0.3 4.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 2.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 2.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 2.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 5.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 8.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.2 GO:0019838 growth factor binding(GO:0019838)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC