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PRJNA195909:zebrafish embryo and larva development
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Results for hbp1
Z-value: 0.90
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Transcription factors associated with hbp1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hbp1 | dr11_v1_chr25_-_3469576_3469576 | 0.75 | 1.9e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr24_+_38301080 Show fit | 2.67 |
ENSDART00000105672
|
myosin binding protein C, fast type b |
|
| chr1_-_59252973 Show fit | 1.75 |
ENSDART00000167061
|
si:ch1073-286c18.5 |
|
| chr13_-_39160018 Show fit | 1.55 |
ENSDART00000168795
|
collagen, type IX, alpha 1b |
|
| chr25_-_31698550 Show fit | 1.43 |
ENSDART00000058400
|
laminin, beta 4 |
|
| chr6_-_24103666 Show fit | 1.41 |
ENSDART00000164915
|
scinderin like a |
|
| chr15_-_15357178 Show fit | 1.35 |
ENSDART00000106120
|
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2 |
|
| chr4_+_5249494 Show fit | 1.34 |
ENSDART00000150391
|
si:ch211-214j24.14 |
|
| chr6_+_23887314 Show fit | 1.29 |
ENSDART00000163188
|
zinc finger protein 648 |
|
| chr14_+_6159356 Show fit | 1.23 |
ENSDART00000157730
|
Bernardinelli-Seip congenital lipodystrophy 2, like |
|
| chr11_-_25418856 Show fit | 1.22 |
ENSDART00000013714
|
GATA binding protein 1a |
Network of associatons between targets according to the STRING database.
First level regulatory network of hbp1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.3 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 1.4 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.3 | 1.3 | GO:2000391 | neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391) |
| 0.0 | 1.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.3 | 1.2 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.3 | 0.9 | GO:0034375 | high-density lipoprotein particle remodeling(GO:0034375) |
| 0.2 | 0.9 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 0.0 | 0.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.9 | GO:0007602 | phototransduction(GO:0007602) |
| 0.1 | 0.8 | GO:0043462 | regulation of ATPase activity(GO:0043462) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 1.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.4 | GO:0005605 | basal lamina(GO:0005605) laminin complex(GO:0043256) |
| 0.0 | 1.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 0.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.8 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.1 | 0.6 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.2 | 0.5 | GO:1902560 | GMP reductase complex(GO:1902560) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 1.3 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 1.2 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.1 | 1.0 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.9 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 0.9 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.9 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.2 | 0.8 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.6 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.5 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 0.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.4 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.3 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |