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PRJNA195909:zebrafish embryo and larva development
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Results for grhl1
Z-value: 2.36
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Transcription factors associated with grhl1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| grhl1 | dr11_v1_chr17_-_32413147_32413147 | 0.88 | 1.8e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_22657566 Show fit | 8.02 |
ENSDART00000141048
|
plac8 onzin related protein 5 |
|
| chr3_-_29977495 Show fit | 5.98 |
ENSDART00000077111
|
hydroxysteroid (17-beta) dehydrogenase 14 |
|
| chr22_+_22021936 Show fit | 5.56 |
ENSDART00000149586
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 |
|
| chr11_+_6116503 Show fit | 5.21 |
ENSDART00000176170
|
nuclear receptor subfamily 2, group F, member 6b |
|
| chr13_+_18533005 Show fit | 5.00 |
ENSDART00000136024
|
finTRIM family, member 14-like |
|
| chr6_+_23057311 Show fit | 4.98 |
ENSDART00000026448
|
envoplakin a |
|
| chr8_-_24252933 Show fit | 4.93 |
ENSDART00000057624
|
zgc:110353 |
|
| chr16_+_7154753 Show fit | 4.32 |
ENSDART00000163281
ENSDART00000168274 |
BMP binding endothelial regulator |
|
| chr15_+_42560354 Show fit | 4.15 |
ENSDART00000059484
|
zgc:110333 |
|
| chr22_+_25672155 Show fit | 4.05 |
ENSDART00000087769
|
si:ch211-250e5.2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of grhl1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.5 | GO:0043049 | otic placode formation(GO:0043049) |
| 0.3 | 5.6 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.1 | 5.0 | GO:0045103 | intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104) |
| 0.2 | 4.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 3.3 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.1 | 3.1 | GO:0046890 | regulation of lipid biosynthetic process(GO:0046890) |
| 0.0 | 2.7 | GO:0009913 | epidermal cell differentiation(GO:0009913) |
| 0.0 | 2.5 | GO:0007596 | blood coagulation(GO:0007596) |
| 0.5 | 2.4 | GO:0045056 | transcytosis(GO:0045056) |
| 0.0 | 2.2 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.6 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 5.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 5.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 4.7 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 4.3 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.2 | 2.7 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.0 | 2.4 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.1 | 2.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 1.9 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.1 | 1.8 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 6.6 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.7 | 5.6 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.0 | 5.2 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) |
| 0.8 | 5.0 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.5 | 4.7 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.3 | 4.7 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.1 | 4.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 3.9 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.1 | 3.8 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 3.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 2.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |