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PRJNA195909:zebrafish embryo and larva development

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Results for gli1+gli2b

Z-value: 1.07

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Transcription factors associated with gli1+gli2b

Gene Symbol Gene ID Gene Info
ENSDARG00000020884 GLI family zinc finger 2b
ENSDARG00000101244 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli2bdr11_v1_chr11_+_43661735_436617350.294.5e-01Click!
gli1dr11_v1_chr6_-_59505589_595055890.206.0e-01Click!

Activity profile of gli1+gli2b motif

Sorted Z-values of gli1+gli2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_20422661 3.08 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr7_+_29952719 2.41 ENSDART00000173737
alpha-tropomyosin
chr7_+_29952169 2.24 ENSDART00000173540
ENSDART00000173940
ENSDART00000173906
ENSDART00000173772
ENSDART00000173506
ENSDART00000039657
alpha-tropomyosin
chr10_+_33171501 2.09 ENSDART00000159666
myosin, light chain 10, regulatory
chr7_+_29951997 2.05 ENSDART00000173453
alpha-tropomyosin
chr12_-_464007 1.67 ENSDART00000106669
dehydrogenase/reductase (SDR family) member 7Cb
chr8_+_1065458 1.58 ENSDART00000081432
sepiapterin reductase b
chr3_-_25814097 1.49 ENSDART00000169706
netrin 1b
chr13_-_9886579 1.47 ENSDART00000101926
si:ch211-117n7.7
chr10_+_43188678 1.43 ENSDART00000012522
versican b
chr21_-_41873065 1.40 ENSDART00000014538
endonuclease, polyU-specific 2
chr19_+_56351 1.32 ENSDART00000168334
collagen, type XIV, alpha 1b
chr8_+_29962635 1.25 ENSDART00000007640
patched 1
chr1_-_21599219 1.24 ENSDART00000148327
ADAMTS-like 7
chr23_+_36052944 1.23 ENSDART00000103149
homeobox C13a
chr24_-_6158933 1.13 ENSDART00000021609
glutamate decarboxylase 2
chr6_-_11768198 1.12 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr13_-_39947335 1.10 ENSDART00000056996
secreted frizzled-related protein 5
chr12_-_17479078 1.09 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr21_-_41873584 1.08 ENSDART00000188089
endonuclease, polyU-specific 2
chr22_+_38762693 1.01 ENSDART00000015016
ENSDART00000150187
alkaline phosphatase, intestinal, tandem duplicate 1
chr2_-_33993533 0.97 ENSDART00000140910
ENSDART00000077304
patched 2
chr1_+_59090743 0.93 ENSDART00000100199
microfibril associated protein 4
chr19_-_26235219 0.91 ENSDART00000104008
dystrobrevin binding protein 1b
chr5_-_51747278 0.91 ENSDART00000192232
LHFPL tetraspan subfamily member 2b
chr3_-_16068236 0.90 ENSDART00000157315
si:dkey-81l17.6
chr12_-_4756478 0.89 ENSDART00000152181
microtubule-associated protein tau a
chr1_-_470812 0.88 ENSDART00000192527
zgc:92518
chr6_-_18976168 0.85 ENSDART00000170039
septin 9b
chr24_+_3972260 0.83 ENSDART00000131753
phosphofructokinase, platelet a
chr16_-_13595027 0.83 ENSDART00000060004
ntl-dependent gene 5
chr19_-_10243148 0.80 ENSDART00000148073
shisa family member 7
chr12_+_27462225 0.80 ENSDART00000105661
mesenchyme homeobox 1
chr7_-_27037990 0.79 ENSDART00000173561
nucleobindin 2a
chr17_-_42213822 0.74 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr20_-_53996193 0.74 ENSDART00000004756
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr10_-_24391030 0.74 ENSDART00000180013
ENSDART00000177914
solute carrier family 43 (amino acid system L transporter), member 2b
chr24_-_17029374 0.73 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr3_+_19621034 0.72 ENSDART00000025358
integrin beta 3a
chr6_+_7123980 0.70 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
chr13_-_9598320 0.68 ENSDART00000184613
carboxypeptidase X (M14 family), member 1a
chr7_+_31871830 0.65 ENSDART00000139899
myosin binding protein C, cardiac
chr25_-_28384954 0.65 ENSDART00000073500
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr18_+_49225552 0.64 ENSDART00000135026
si:ch211-136a13.1
chr19_+_49721 0.64 ENSDART00000160489
collagen, type XIV, alpha 1b
chr12_-_30338779 0.63 ENSDART00000192511
von Willebrand factor A domain containing 2
chr16_-_37964325 0.63 ENSDART00000148801
melanocortin 2 receptor accessory protein 2a
chr14_-_33821515 0.62 ENSDART00000173218
vimentin-related 2
chr21_+_45819662 0.61 ENSDART00000193362
ENSDART00000184255
paired-like homeodomain 1
chr6_+_42918933 0.61 ENSDART00000064896
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr20_+_26095530 0.60 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr17_+_30587333 0.59 ENSDART00000156500
NHS-like 1a
chr11_+_44300548 0.58 ENSDART00000191626

chr11_+_30306606 0.58 ENSDART00000128276
ENSDART00000190222
UDP glucuronosyltransferase 1 family, polypeptide B4
chr1_+_31706668 0.57 ENSDART00000057879
arsenite methyltransferase
chr1_+_55293424 0.55 ENSDART00000152464
zgc:172106
chr10_-_34907477 0.55 ENSDART00000099604
spartin a
chr20_+_13969414 0.54 ENSDART00000049864
retinal degeneration 3
chr18_-_17485419 0.54 ENSDART00000018764
forkhead box L1
chr4_+_5132951 0.54 ENSDART00000103279
cyclin D2, b
chr10_-_24391716 0.54 ENSDART00000141332
ENSDART00000100772
solute carrier family 43 (amino acid system L transporter), member 2b
chr5_-_43959972 0.54 ENSDART00000180517
si:ch211-204c21.1
chr23_+_28582865 0.53 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr19_+_9004256 0.52 ENSDART00000186401
ENSDART00000091443
si:ch211-81a5.1
chr10_-_35542071 0.52 ENSDART00000162139
si:ch211-244c8.4
chr20_+_27194833 0.50 ENSDART00000150072
si:dkey-85n7.8
chr20_-_28642061 0.48 ENSDART00000135513
regulator of G protein signaling 6
chr2_+_54482603 0.48 ENSDART00000130977
ENSDART00000183090
microtubule crosslinking factor 1
chr7_+_15871156 0.48 ENSDART00000145946
paired box 6b
chr25_+_7461624 0.48 ENSDART00000170569
synaptotagmin XII
chr2_-_10896745 0.47 ENSDART00000114609
CUB domain containing protein 2
chr23_+_18779043 0.45 ENSDART00000158267
epithelial membrane protein 3b
chr19_+_18493782 0.44 ENSDART00000160992
FK506 binding protein 10a
chr23_-_27152866 0.44 ENSDART00000141305
si:dkey-157g16.6
chr21_-_30415524 0.44 ENSDART00000101036
GrpE-like 2, mitochondrial
chr21_-_8370500 0.42 ENSDART00000055328
NIMA-related kinase 6
chr10_-_39154594 0.41 ENSDART00000148825
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr4_+_27130412 0.38 ENSDART00000145083
bromodomain containing 1a
chr13_+_3954540 0.37 ENSDART00000092646
leucine rich repeat containing 73
chr6_-_436658 0.37 ENSDART00000191515
GRB2-related adaptor protein 2b
chr8_-_52859301 0.37 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr25_+_30298377 0.37 ENSDART00000153622
chromosome 11 open reading frame 96
chr25_+_32474031 0.36 ENSDART00000152124
sulfide quinone oxidoreductase
chr4_-_77506362 0.35 ENSDART00000174387
ENSDART00000181181

chr25_+_245438 0.35 ENSDART00000004689
zgc:92481
chr20_-_54377933 0.34 ENSDART00000182664
ectonucleoside triphosphate diphosphohydrolase 5b
chr18_-_45617146 0.34 ENSDART00000146543
wilms tumor 1b
chr17_-_33716688 0.34 ENSDART00000043651
dynein, axonemal, light chain 1
chr20_-_25626693 0.33 ENSDART00000132247
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr14_+_25464681 0.32 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr5_+_10046643 0.32 ENSDART00000137543
ENSDART00000186917
glutathione S-transferase theta 2
chr4_-_23839789 0.31 ENSDART00000143571
USP6 N-terminal like
chr23_+_42304602 0.31 ENSDART00000166004
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr23_+_26009266 0.31 ENSDART00000054025
si:dkey-78k11.9
chr8_+_28469054 0.29 ENSDART00000062716
solute carrier family 52 (riboflavin transporter), member 3
chr22_+_24389135 0.29 ENSDART00000157861
prolyl 3-hydroxylase 2
chr8_-_16592491 0.29 ENSDART00000101655
calreticulin
chr20_-_915234 0.28 ENSDART00000164816
cannabinoid receptor 1
chr21_+_10739846 0.28 ENSDART00000084011
complexin 4a
chr5_+_40224938 0.28 ENSDART00000142897
si:dkey-193c22.2
chr17_-_26604946 0.28 ENSDART00000087062
family with sequence similarity 149, member B1
chr2_+_51783120 0.28 ENSDART00000177559
crystallin, gamma N1
chr7_+_4162994 0.28 ENSDART00000172800
si:ch211-63p21.1
chr13_+_31583034 0.27 ENSDART00000111763
SIX homeobox 6a
chr1_+_59090583 0.27 ENSDART00000150658
microfibril associated protein 4
chr4_-_5856200 0.26 ENSDART00000121936
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr11_+_40831620 0.26 ENSDART00000160023
ERBB receptor feedback inhibitor 1a
chr15_-_34056733 0.25 ENSDART00000170130
ENSDART00000188272
si:dkey-30e9.7
chr2_-_44199722 0.25 ENSDART00000140633
ENSDART00000145728
succinate dehydrogenase complex, subunit C, integral membrane protein
chr22_-_20733822 0.25 ENSDART00000133780
si:dkey-3k20.1
chr25_+_32473433 0.24 ENSDART00000152326
sulfide quinone oxidoreductase
chr4_+_10721795 0.24 ENSDART00000136000
ENSDART00000067253
stabilin 2
chr13_-_17723417 0.23 ENSDART00000183834
voltage-dependent anion channel 2
chr7_+_18075504 0.23 ENSDART00000173689
si:ch73-40a2.1
chr19_-_42651615 0.22 ENSDART00000123360
sushi domain containing 5
chr14_-_29859067 0.22 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr18_+_25653599 0.22 ENSDART00000007856
FK506 binding protein 16
chr16_-_31644545 0.22 ENSDART00000181634

chr13_+_7242916 0.21 ENSDART00000184238
apoptosis-inducing factor, mitochondrion-associated, 2
chr11_-_21304452 0.20 ENSDART00000163008
si:dkey-85p17.3
chr24_-_21587335 0.20 ENSDART00000091528
G protein-coupled receptor 12
chr17_-_722218 0.20 ENSDART00000160385
solute carrier family 25 member 29
chr12_-_26415499 0.19 ENSDART00000185779
synaptopodin 2-like b
chr4_+_57881965 0.18 ENSDART00000162234
si:dkeyp-44b5.4
chr22_-_3261879 0.18 ENSDART00000159643
G protein-coupled receptor 35, tandem duplicate 1
chr3_-_8285123 0.18 ENSDART00000158699
ENSDART00000138588
tripartite motif containing 35-9
chr25_-_3087556 0.18 ENSDART00000193249
bestrophin 1
chr6_-_30859656 0.17 ENSDART00000156235
phosphodiesterase 4B, cAMP-specific a
chr16_-_22930925 0.17 ENSDART00000133819
si:dkey-246i14.3
chr1_-_31505144 0.16 ENSDART00000087115
regulating synaptic membrane exocytosis 1b
chr21_+_261490 0.16 ENSDART00000177919
Janus kinase 2a
chr1_+_57235896 0.16 ENSDART00000152621
si:dkey-27j5.7
chr10_-_45379831 0.16 ENSDART00000186205

chr5_-_25123807 0.15 ENSDART00000183171
ATP-binding cassette, sub-family A (ABC1), member 2
chr5_-_25620594 0.15 ENSDART00000189346
cytochrome P450, family 1, subfamily D, polypeptide 1
chr17_-_50331351 0.15 ENSDART00000149294
otoferlin b
chr19_-_6988837 0.15 ENSDART00000145741
ENSDART00000167640
zinc finger protein 384 like
chr4_-_52165969 0.15 ENSDART00000171130
si:dkeyp-44b5.4
chr2_+_30147504 0.14 ENSDART00000190947
potassium voltage-gated channel, Shab-related subfamily, member 2
chr8_-_40327397 0.13 ENSDART00000074125
apelin receptor a
chr16_+_13822137 0.13 ENSDART00000163251
folliculin
chr23_+_4414164 0.12 ENSDART00000192762
wingless-type MMTV integration site family, member 7Ab
chr6_+_28796773 0.12 ENSDART00000168237
ENSDART00000163541
tumor protein p63
chr16_-_40373836 0.12 ENSDART00000134498
si:dkey-242e21.3
chr5_-_22615087 0.12 ENSDART00000146035
zgc:113208
chr14_-_15155384 0.11 ENSDART00000172666
UV-stimulated scaffold protein A
chr23_+_4414343 0.10 ENSDART00000081821
wingless-type MMTV integration site family, member 7Ab
chr22_-_3344613 0.09 ENSDART00000165600
thromboxane A2 receptor
chr23_+_44049509 0.09 ENSDART00000102003
TXK tyrosine kinase
chr9_-_46399611 0.09 ENSDART00000164914
ENSDART00000145931
lactase
si:dkey-79p17.3
chr5_+_52844681 0.08 ENSDART00000162459
ENSDART00000184914
scavenger receptor class B, member 2a
chr4_+_63253425 0.08 ENSDART00000193510
si:ch211-258f1.3
chr23_+_34005792 0.07 ENSDART00000132668
si:ch211-207e14.4
chr24_-_38574631 0.07 ENSDART00000154539
solute carrier family 17 (vesicular glutamate transporter), member 7b
chr15_+_16525126 0.07 ENSDART00000193455
polypeptide N-acetylgalactosaminyltransferase 17
chr22_+_19522982 0.07 ENSDART00000192428
ENSDART00000190812
si:dkey-78l4.13
chr18_+_14529005 0.06 ENSDART00000186379
potassium voltage-gated channel, subfamily G, member 4a
chr18_+_30567945 0.06 ENSDART00000078894
interferon regulatory factor 8
chr10_+_40235959 0.05 ENSDART00000145862
GRAM domain containing 1Ba
chr21_+_27340682 0.05 ENSDART00000011305
dipeptidyl-peptidase 3
chr4_-_17741513 0.04 ENSDART00000141680
myosin binding protein C, slow type
chrM_+_9735 0.04 ENSDART00000093613
cytochrome c oxidase III, mitochondrial
chr14_+_15597049 0.04 ENSDART00000159732
si:dkey-203a12.8
chr6_+_11850359 0.03 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
bromodomain adjacent to zinc finger domain, 2Ba
chr21_+_11560153 0.03 ENSDART00000065842
CD8a molecule
chr16_+_12632428 0.02 ENSDART00000184600
ENSDART00000180537
N-acetyltransferase 14 (GCN5-related, putative)
chr2_-_12242695 0.02 ENSDART00000158175
G protein-coupled receptor 158b
chr3_-_15444396 0.01 ENSDART00000104361
si:dkey-56d12.4
chr13_+_228045 0.01 ENSDART00000161091
zgc:64201
chr23_-_33038423 0.01 ENSDART00000180539
plexin A2
chr5_-_34185497 0.00 ENSDART00000146321
fibrinogen C domain containing 1
chr18_-_16395668 0.00 ENSDART00000186004
mgat4 family, member C

Network of associatons between targets according to the STRING database.

First level regulatory network of gli1+gli2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.4 1.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4 1.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 1.1 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.5 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 0.7 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 2.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 0.9 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.2 0.6 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 0.6 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.2 0.7 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.2 1.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 3.1 GO:0014823 response to activity(GO:0014823)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 1.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.8 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 6.0 GO:0061515 myeloid cell development(GO:0061515)
0.1 0.6 GO:0097009 energy homeostasis(GO:0097009)
0.1 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:2000253 cannabinoid signaling pathway(GO:0038171) positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.5 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.5 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.8 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 3.1 GO:0005861 troponin complex(GO:0005861)
0.1 6.7 GO:0005884 actin filament(GO:0005884)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 1.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 1.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 1.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.7 GO:0070051 fibrinogen binding(GO:0070051)
0.2 0.6 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.2 0.6 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 0.6 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 1.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 6.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 2.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.2 GO:0003823 antigen binding(GO:0003823)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.6 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis