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PRJNA195909:zebrafish embryo and larva development

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Results for gfi1aa+gfi1ab

Z-value: 1.08

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Transcription factors associated with gfi1aa+gfi1ab

Gene Symbol Gene ID Gene Info
ENSDARG00000020746 growth factor independent 1A transcription repressor a
ENSDARG00000044457 growth factor independent 1A transcription repressor b
ENSDARG00000114140 growth factor independent 1A transcription repressor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gfi1abdr11_v1_chr6_-_29007493_290074930.908.7e-04Click!
gfi1aadr11_v1_chr2_+_10766744_107667440.674.9e-02Click!

Activity profile of gfi1aa+gfi1ab motif

Sorted Z-values of gfi1aa+gfi1ab motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_15433518 2.87 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr17_+_15433671 2.71 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr13_+_4671698 2.45 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
phospholipase A2, group XIIB
chr19_-_10551394 2.02 ENSDART00000186815
ENSDART00000181041
lens intrinsic membrane protein 2.4
chr3_-_32818607 1.76 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr9_-_18877597 1.65 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr16_+_20915319 1.61 ENSDART00000079383
homeobox A9b
chr12_+_27127139 1.47 ENSDART00000025966
homeobox B6b
chr21_+_26697536 1.47 ENSDART00000004109
guanine nucleotide binding protein (G protein), gamma 3
chr4_-_16330368 1.29 ENSDART00000128932
epiphycan
chr7_+_38750871 1.27 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr13_-_39159810 1.15 ENSDART00000131508
collagen, type IX, alpha 1b
chr23_+_44883805 1.13 ENSDART00000182805
si:ch73-361h17.1
chr9_+_48007081 1.13 ENSDART00000060593
ENSDART00000099835
zgc:92380
chr9_-_3400727 1.12 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr1_-_38195012 1.06 ENSDART00000020409
heart and neural crest derivatives expressed 2
chr17_-_21066075 1.01 ENSDART00000078763
ENSDART00000104327
visual system homeobox 1 homolog, chx10-like
chr13_-_39160018 1.00 ENSDART00000168795
collagen, type IX, alpha 1b
chr8_+_15254564 0.99 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr12_+_25600685 0.98 ENSDART00000077157
SIX homeobox 3b
chr5_-_19400166 0.97 ENSDART00000008994
forkhead box N4
chr20_+_23238833 0.97 ENSDART00000074167
OCIA domain containing 2
chr17_-_36936649 0.96 ENSDART00000145236
dihydropyrimidinase-like 5a
chr17_-_36936856 0.95 ENSDART00000010274
ENSDART00000188887
dihydropyrimidinase-like 5a
chr6_+_29217392 0.94 ENSDART00000006386
ATPase Na+/K+ transporting subunit beta 1a
chr23_-_21453614 0.94 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr18_-_1185772 0.94 ENSDART00000143245
neuroplastin b
chr15_-_24869826 0.94 ENSDART00000127047
tumor suppressor candidate 5a
chr13_-_46429220 0.93 ENSDART00000149125
ENSDART00000098269
ENSDART00000150061
ENSDART00000080916
fibroblast growth factor receptor 2
chr10_+_39084354 0.90 ENSDART00000158245
si:ch73-1a9.3
chr12_+_22870372 0.90 ENSDART00000182264
ENSDART00000191789
ENSDART00000130594
ENSDART00000190433
actin filament associated protein 1
chr6_+_35362225 0.90 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr21_+_35215810 0.89 ENSDART00000135256
ubiquitin domain containing 2
chr2_-_16562505 0.88 ENSDART00000156406
ATPase Na+/K+ transporting subunit beta 3a
chr23_-_21471022 0.88 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr14_-_40389699 0.87 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr17_+_12698532 0.87 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr11_+_37201483 0.86 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
chr25_-_15049694 0.86 ENSDART00000162485
ENSDART00000164384
ENSDART00000165632
ENSDART00000159490
paired box 6a
chr20_-_48485354 0.86 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr16_-_20312146 0.85 ENSDART00000134980
si:dkeyp-86h10.3
chr9_-_45602978 0.85 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr17_-_6382392 0.84 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
taxilin beta b
chr16_+_29650698 0.84 ENSDART00000137153
tropomodulin 4 (muscle)
chr23_+_21459263 0.82 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr1_-_20271138 0.82 ENSDART00000185931
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_54013457 0.82 ENSDART00000012104
ENSDART00000126339
deltaA
chr6_-_13783604 0.82 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr15_+_19652807 0.82 ENSDART00000134321
ENSDART00000054426
lens intrinsic membrane protein 2.3
chr14_+_33722950 0.82 ENSDART00000075312
apelin
chr14_+_35806605 0.81 ENSDART00000173093
glutamate receptor, ionotropic, AMPA 2b
chr5_+_64732270 0.81 ENSDART00000134241
olfactomedin 1a
chr5_+_43603794 0.80 ENSDART00000134633
si:dkey-40c11.2
chr15_+_36115955 0.80 ENSDART00000032702
somatostatin 1, tandem duplicate 2
chr17_+_26569601 0.80 ENSDART00000153897
neuron-derived neurotrophic factor , like
chr23_+_8797143 0.79 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr25_+_21829777 0.78 ENSDART00000027393
creatine kinase, mitochondrial 1
chr7_+_26629084 0.78 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr15_+_45643787 0.78 ENSDART00000055995
ENSDART00000157750
S-antigen; retina and pineal gland (arrestin) b
chr12_-_31103187 0.78 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
transcription factor 7 like 2
chr16_+_23397785 0.78 ENSDART00000148961
S100 calcium binding protein A10b
chr3_+_23703704 0.76 ENSDART00000024256
homeobox B6a
chr7_-_51546386 0.76 ENSDART00000174306
NHS-like 2
chr22_+_16022211 0.75 ENSDART00000062618
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr23_+_21455152 0.75 ENSDART00000158511
ENSDART00000161321
ENSDART00000160731
ENSDART00000137573
hairy-related 4, tandem duplicate 2
chr11_+_30310170 0.75 ENSDART00000127797
UDP glucuronosyltransferase 1 family, polypeptide B3
chr13_+_25433774 0.74 ENSDART00000141255
si:dkey-51a16.9
chr3_+_31621774 0.74 ENSDART00000076636
frizzled class receptor 2
chr9_+_3388099 0.73 ENSDART00000019910
distal-less homeobox 1a
chr4_+_6643421 0.73 ENSDART00000099462
G protein-coupled receptor 85
chr21_+_20771082 0.73 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr5_-_66702479 0.72 ENSDART00000129197
meningioma 1b
chr4_-_16412084 0.72 ENSDART00000188460
decorin
chr16_+_11724230 0.72 ENSDART00000060266
carcinoembryonic antigen-related cell adhesion molecule 1
chr18_-_16123222 0.71 ENSDART00000061189
sarcospan (Kras oncogene-associated gene)
chr12_+_22258962 0.71 ENSDART00000131175
wingless-type MMTV integration site family, member 3
chr10_+_16592851 0.70 ENSDART00000187508
ENSDART00000101142
chondroitin sulfate synthase 3
chr25_-_23526058 0.70 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr23_+_22656477 0.69 ENSDART00000009337
ENSDART00000133322
enolase 1a, (alpha)
chr5_+_70155935 0.68 ENSDART00000165570
regulator of G protein signaling 3a
chr5_-_65782783 0.68 ENSDART00000130888
ENSDART00000050855
notch 1b
chr21_-_26495700 0.67 ENSDART00000109379
CD248 molecule, endosialin b
chr21_-_44104600 0.66 ENSDART00000044599
organic anion transporter X
chr7_-_26408472 0.66 ENSDART00000111494
galactose-3-O-sulfotransferase 4
chr23_+_36101185 0.66 ENSDART00000103139
homeobox C8a
chr21_-_4032650 0.66 ENSDART00000151648
netrin g2b
chr1_-_54947592 0.65 ENSDART00000129710
cartilage acidic protein 1a
chr11_+_21910343 0.64 ENSDART00000161485
forkhead box P4
chr11_+_21910752 0.64 ENSDART00000114288
forkhead box P4
chr18_+_16744307 0.64 ENSDART00000179872
ENSDART00000133490
lymphatic vessel endothelial hyaluronic receptor 1b
chr7_-_24364536 0.63 ENSDART00000064789
thioredoxin
chr11_-_39044595 0.63 ENSDART00000065461
claudin 19
chr14_-_17563773 0.63 ENSDART00000082667
fibroblast growth factor receptor like 1a
chr21_-_36972127 0.63 ENSDART00000100310
drebrin 1
chr16_+_23282655 0.63 ENSDART00000015956
ephrin-A1b
chr13_-_22862133 0.62 ENSDART00000138563
phenazine biosynthesis-like protein domain containing 2
chr5_+_17727310 0.62 ENSDART00000147657
fibrosin-like 1
chr1_-_46981134 0.62 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr6_+_1787160 0.62 ENSDART00000113505
myosin, light chain 9b, regulatory
chr21_+_30351256 0.62 ENSDART00000078341
forkhead box I3a
chr23_+_36095260 0.61 ENSDART00000127384
homeobox C9a
chr8_+_37700090 0.61 ENSDART00000187885
ENSDART00000127633
adrenoceptor beta 3a
chr24_+_14713776 0.61 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr15_-_19250543 0.61 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr22_-_13042992 0.61 ENSDART00000028787
aryl hydrocarbon receptor 1b
chr10_+_35265083 0.61 ENSDART00000048831
transmembrane protein 120A
chr13_-_16222388 0.60 ENSDART00000182861
zgc:110045
chr8_+_39619087 0.60 ENSDART00000134822
musashi RNA-binding protein 1
chr21_-_10773344 0.60 ENSDART00000063244
gastrin-releasing peptide
chr11_+_30306606 0.60 ENSDART00000128276
ENSDART00000190222
UDP glucuronosyltransferase 1 family, polypeptide B4
chr13_+_27951688 0.59 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr17_-_32863250 0.59 ENSDART00000167292
prospero homeobox 1a
chr7_-_60831082 0.59 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr7_+_40638210 0.59 ENSDART00000052236
motor neuron and pancreas homeobox 1
chr25_+_14017609 0.59 ENSDART00000129105
ENSDART00000125733
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr13_+_51579851 0.59 ENSDART00000163847
NK6 homeobox 2
chr12_+_6002715 0.59 ENSDART00000114961
si:ch211-131k2.3
chr19_+_4912817 0.58 ENSDART00000101658
ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_+_18960914 0.58 ENSDART00000139730
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr21_-_43131752 0.58 ENSDART00000024137
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr24_-_8729531 0.58 ENSDART00000082346
transcription factor AP-2 alpha
chr12_+_2399130 0.57 ENSDART00000075179
V-set and transmembrane domain containing 4b
chr15_+_22311803 0.57 ENSDART00000150182
hepatic and glial cell adhesion molecule a
chr14_+_7452302 0.57 ENSDART00000130388
GDNF family receptor alpha 3
chr18_+_38749547 0.56 ENSDART00000143735
si:ch211-215d8.2
chr1_+_59538755 0.56 ENSDART00000166354
Sp6 transcription factor
chr10_+_43994471 0.56 ENSDART00000138242
ENSDART00000186359
claudin 5b
chr5_-_36948586 0.56 ENSDART00000193606
H3 histone, family 3C
chr7_+_56098590 0.56 ENSDART00000098453
cadherin 15, type 1, M-cadherin (myotubule)
chr16_+_813780 0.56 ENSDART00000162474
ENSDART00000161774
iroquois homeobox 1a
chr8_+_54055390 0.56 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr8_-_19216657 0.56 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
chr3_+_19621034 0.55 ENSDART00000025358
integrin beta 3a
chr19_-_17774875 0.55 ENSDART00000151133
ENSDART00000130695
DNA topoisomerase II beta
chr9_-_7684002 0.55 ENSDART00000016360
si:ch73-199e17.1
chr9_-_7683799 0.55 ENSDART00000102713
si:ch73-199e17.1
chr23_+_36178104 0.55 ENSDART00000103131
homeobox C1a
chr1_+_54037077 0.55 ENSDART00000109386
TRIO and F-actin binding protein a
chr11_+_25634041 0.55 ENSDART00000033657
glutamate receptor, metabotropic 6b
chr5_-_12219572 0.55 ENSDART00000167834
nitric oxide synthase 1 (neuronal)
chr5_-_28029558 0.55 ENSDART00000078649
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr16_-_42894628 0.55 ENSDART00000045600
hemochromatosis type 2
chr8_+_1766206 0.54 ENSDART00000021820
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr15_-_21014015 0.54 ENSDART00000144991
si:ch211-212c13.10
chr4_-_7212875 0.52 ENSDART00000161297
leucine rich repeat neuronal 3b
chr18_+_17583479 0.52 ENSDART00000186977
ENSDART00000010998
solute carrier family 12 (sodium/chloride transporter), member 3
chr6_+_42819337 0.52 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr6_-_19023468 0.51 ENSDART00000184729
septin 9b
chr17_-_26911852 0.51 ENSDART00000045842
regulator of calcineurin 3
chr3_+_40170216 0.51 ENSDART00000011568
synaptogyrin 3a
chr2_-_32558795 0.51 ENSDART00000140026
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr6_-_48094342 0.50 ENSDART00000137458
solute carrier family 2 (facilitated glucose transporter), member 1b
chr17_-_12385308 0.50 ENSDART00000080927
synaptosomal-associated protein, 25b
chr20_-_31427390 0.50 ENSDART00000007735
uronyl-2-sulfotransferase
chr9_-_1965727 0.50 ENSDART00000082354
homeobox D9a
chr9_-_18716 0.50 ENSDART00000164763

chr10_+_21722892 0.50 ENSDART00000162855
protocadherin 1 gamma 13
chr21_-_23475361 0.50 ENSDART00000156658
ENSDART00000157454
neural cell adhesion molecule 1a
chr25_+_13406069 0.50 ENSDART00000010495
zinc and ring finger 1
chr1_-_51734524 0.49 ENSDART00000109640
ENSDART00000122628
JunB proto-oncogene, AP-1 transcription factor subunit a
chr13_+_21779975 0.49 ENSDART00000021556
si:ch211-51a6.2
chr14_+_34514336 0.49 ENSDART00000024440
forkhead box I3b
chr7_+_32369026 0.48 ENSDART00000169588
leucine-rich repeat containing G protein-coupled receptor 4
chr14_-_40390757 0.48 ENSDART00000149443
protocadherin 19
chr5_-_36328688 0.48 ENSDART00000011399
ephrin-B1
chr20_-_26491567 0.48 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr4_-_2545310 0.48 ENSDART00000150619
ENSDART00000140760
E2F transcription factor 7
chr16_-_29528198 0.48 ENSDART00000150028
one cut domain, family member, like
chr14_-_41678357 0.48 ENSDART00000185925
fibroblast growth factor receptor like 1b
chr14_-_39074539 0.48 ENSDART00000030509
glycine receptor, alpha 4a
chr4_+_4803698 0.47 ENSDART00000129252
solute carrier family 13 (sodium/sulfate symporter), member 4
chr7_-_22132265 0.47 ENSDART00000125284
ENSDART00000112978
neuroligin 2a
chr10_+_29265463 0.47 ENSDART00000155390
CREB/ATF bZIP transcription factor
chr5_+_38276582 0.47 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr20_-_20533865 0.46 ENSDART00000125039
SIX homeobox 6b
chr24_+_4977862 0.45 ENSDART00000114537
zic family member 4
chr7_-_12968689 0.45 ENSDART00000173115
ENSDART00000013690
ribosomal protein, large P2, like
chr8_+_26192930 0.45 ENSDART00000137391
cadherin, EGF LAG seven-pass G-type receptor 3
chr20_+_52554352 0.45 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr8_+_29962635 0.44 ENSDART00000007640
patched 1
chr18_-_14836600 0.44 ENSDART00000045232
metastasis suppressor 1-like a
chr9_+_23255410 0.44 ENSDART00000113241
ENSDART00000137231
transmembrane protein 163a
chr8_-_14179798 0.44 ENSDART00000040645
ENSDART00000146749
ras homolog gene family, member Aa
chr14_+_49135264 0.44 ENSDART00000084119
si:ch1073-44g3.1
chr14_+_30491890 0.44 ENSDART00000131174
fibroblast growth factor 20b
chr21_-_14310159 0.44 ENSDART00000155097
si:ch211-196i2.1
chr13_-_7575216 0.44 ENSDART00000159443
paired-like homeodomain 3
chr2_+_48288461 0.43 ENSDART00000141495
hes family bHLH transcription factor 6
chr23_+_22200467 0.43 ENSDART00000025414
solute carrier family 2 (facilitated glucose transporter), member 1a
chr2_-_10062575 0.43 ENSDART00000091726
family with sequence similarity 78, member B a
chr25_-_5963535 0.43 ENSDART00000155751
NUAK family, SNF1-like kinase, 1b
chr8_+_24747865 0.43 ENSDART00000078656
solute carrier family 16, member 4
chr8_-_2434282 0.42 ENSDART00000137262
ENSDART00000134044
voltage-dependent anion channel 3
chr18_+_5490668 0.42 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr9_-_1984604 0.42 ENSDART00000082339
homeobox D12a
chr4_+_22480169 0.42 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr14_+_33723309 0.42 ENSDART00000132488
apelin
chr7_+_25920792 0.42 ENSDART00000026295
arrestin, beta 2b
chr15_+_28368644 0.42 ENSDART00000168453
solute carrier family 43 (amino acid system L transporter), member 2a
chr24_-_26304386 0.42 ENSDART00000175416
otospiralin

Network of associatons between targets according to the STRING database.

First level regulatory network of gfi1aa+gfi1ab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 1.0 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.3 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 1.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 2.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.3 0.8 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.2 0.7 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 1.7 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.2 1.1 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 1.3 GO:0006953 acute inflammatory response(GO:0002526) acute-phase response(GO:0006953)
0.2 1.2 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 4.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 1.2 GO:0055016 hypochord development(GO:0055016)
0.2 0.8 GO:0010226 response to lithium ion(GO:0010226)
0.2 0.5 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.2 2.5 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 0.5 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.7 GO:2000051 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.9 GO:0098773 skin epidermis development(GO:0098773)
0.1 0.8 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.9 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.6 GO:0048909 anterior lateral line nerve development(GO:0048909)
0.1 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 1.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 1.5 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.6 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 1.9 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.8 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 0.6 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.6 GO:0007412 axon target recognition(GO:0007412)
0.1 0.4 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.9 GO:0021794 thalamus development(GO:0021794)
0.1 0.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.6 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.3 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.3 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.3 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.6 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.4 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.8 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.8 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.7 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0019233 sensory perception of pain(GO:0019233)
0.1 1.8 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 0.4 GO:0046323 glucose import(GO:0046323)
0.1 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.9 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 1.5 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.3 GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0 0.5 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.6 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.6 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.4 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.5 GO:0001964 startle response(GO:0001964)
0.0 0.3 GO:2001057 reactive nitrogen species metabolic process(GO:2001057)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.6 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.4 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.2 GO:0070973 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0050891 respiratory burst(GO:0045730) multicellular organismal water homeostasis(GO:0050891)
0.0 1.4 GO:0072175 epithelial tube formation(GO:0072175)
0.0 0.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.4 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.3 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.7 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.2 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0097028 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.1 GO:0031100 organ regeneration(GO:0031100)
0.0 0.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.9 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.7 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.3 GO:0007379 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.2 0.6 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 0.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.2 GO:1904949 ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 1.6 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.3 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031704 apelin receptor binding(GO:0031704)
0.4 5.6 GO:0005504 fatty acid binding(GO:0005504)
0.3 0.8 GO:0031716 calcitonin receptor binding(GO:0031716)
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.6 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.2 0.5 GO:0046978 TAP1 binding(GO:0046978)
0.2 1.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 1.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 2.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.6 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.9 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 2.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.9 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.7 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0019809 spermidine binding(GO:0019809)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.0 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.5 GO:0008201 heparin binding(GO:0008201)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0098918 structural constituent of presynaptic active zone(GO:0098882) structural constituent of synapse(GO:0098918)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 19.3 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.9 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.5 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport