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PRJNA195909:zebrafish embryo and larva development

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Results for gcm2

Z-value: 0.64

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Transcription factors associated with gcm2

Gene Symbol Gene ID Gene Info
ENSDARG00000045413 glial cells missing transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gcm2dr11_v1_chr24_-_8831866_88319120.665.5e-02Click!

Activity profile of gcm2 motif

Sorted Z-values of gcm2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_45305645 1.07 ENSDART00000172488
calpain 3a, (p94)
chr18_-_21218851 0.86 ENSDART00000060160
calbindin 2a
chr7_-_74090168 0.79 ENSDART00000050528
tyrosinase-related protein 1a
chr9_-_3400727 0.76 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr16_-_20312146 0.76 ENSDART00000134980
si:dkeyp-86h10.3
chr24_-_6158933 0.75 ENSDART00000021609
glutamate decarboxylase 2
chr21_-_43117327 0.74 ENSDART00000122352
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr1_-_20911297 0.74 ENSDART00000078271
carboxypeptidase E
chr25_+_1732838 0.73 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr20_+_28434196 0.73 ENSDART00000034245
D4, zinc and double PHD fingers, family 3
chr19_-_47452874 0.72 ENSDART00000025931
transcription factor AP-2 epsilon
chr19_+_56351 0.67 ENSDART00000168334
collagen, type XIV, alpha 1b
chr1_-_44940830 0.65 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr10_+_4095917 0.63 ENSDART00000114533
meningioma 1a
chr14_+_7140997 0.61 ENSDART00000170994
ENSDART00000129898
cathepsin F
chr6_+_42819337 0.60 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr22_-_5006801 0.60 ENSDART00000106166
retinal homeobox gene 1
chr17_-_35881841 0.57 ENSDART00000110040
SRY (sex determining region Y)-box 11a
chr16_+_12267672 0.57 ENSDART00000060037
zgc:92606
chr16_+_25407021 0.56 ENSDART00000187489
ENSDART00000086333
jumonji, AT rich interactive domain 2a
chr6_+_42818963 0.55 ENSDART00000184833
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr25_-_18125769 0.54 ENSDART00000140484
kit ligand a
chr1_-_20928772 0.53 ENSDART00000078277
methylsterol monooxygenase 1
chr8_+_49570884 0.50 ENSDART00000182117
ENSDART00000108613
RAS and EF-hand domain containing
chr7_-_26306546 0.50 ENSDART00000140817
zgc:77439
chr3_+_32492467 0.49 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr21_-_3452683 0.49 ENSDART00000009740
SMAD family member 7
chr25_-_28443607 0.48 ENSDART00000157243
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr10_-_39130839 0.48 ENSDART00000061274
ENSDART00000148648
ribosomal protein S25
chr1_-_51157660 0.48 ENSDART00000137172
jagged 1a
chr24_-_21258945 0.47 ENSDART00000111025
BOC cell adhesion associated, oncogene regulated
chr14_-_413273 0.46 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr17_+_53250802 0.44 ENSDART00000143819
vasohibin 1
chr24_+_25069609 0.44 ENSDART00000115165
APC membrane recruitment protein 2
chr1_-_26293203 0.42 ENSDART00000180140
CXXC finger 4
chr10_+_37145007 0.40 ENSDART00000131777
CUE domain containing 1a
chr14_-_2602445 0.39 ENSDART00000166910
eukaryotic translation termination factor 1a
chr1_+_34295925 0.39 ENSDART00000075584
potassium channel tetramerisation domain containing 12.2
chr4_+_19534833 0.39 ENSDART00000140028
leucine rich repeat containing 4.1
chr1_+_5402476 0.38 ENSDART00000040204
tubulin, alpha 8 like 2
chr8_+_23521974 0.38 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr20_+_17739923 0.37 ENSDART00000024627
cadherin 2, type 1, N-cadherin (neuronal)
chr8_+_30797363 0.37 ENSDART00000077280
matrix metallopeptidase 11a
chr1_-_26292897 0.37 ENSDART00000112899
ENSDART00000185410
CXXC finger 4
chr5_-_23317477 0.37 ENSDART00000090171
neuroligin 3b
chr7_-_20453661 0.36 ENSDART00000174001
netrin 5
chr19_+_31183495 0.35 ENSDART00000088618
mesenchyme homeobox 2b
chr6_+_39499623 0.35 ENSDART00000036057
si:ch211-173n18.3
chr1_+_44941031 0.35 ENSDART00000141145
si:dkey-9i23.16
chr15_+_618081 0.34 ENSDART00000181518
si:ch211-210b2.1
chr1_-_51157454 0.33 ENSDART00000047851
jagged 1a
chr6_+_41096058 0.33 ENSDART00000028373
FK506 binding protein 5
chr22_+_5176693 0.32 ENSDART00000160927
ceramide synthase 1
chr22_-_20342260 0.32 ENSDART00000161610
ENSDART00000165667
transcription factor 3b
chr3_-_6768905 0.32 ENSDART00000193638
ENSDART00000123809
ENSDART00000189440
ENSDART00000188335
microtubule associated serine/threonine kinase 1b
chr5_-_16274058 0.32 ENSDART00000090684
kringle containing transmembrane protein 1
chr17_+_443264 0.32 ENSDART00000159086
zgc:195050
chr1_+_54043563 0.32 ENSDART00000149760
TRIO and F-actin binding protein a
chr13_+_15004398 0.31 ENSDART00000057810
empty spiracles homeobox 1
chr17_-_43665366 0.30 ENSDART00000127945
early growth response 2a
chr22_+_5176255 0.30 ENSDART00000092647
ceramide synthase 1
chr21_-_1799265 0.29 ENSDART00000066623
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr21_+_1380099 0.29 ENSDART00000184516
transcription factor 4
chr16_+_5678071 0.29 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
chr3_-_32299892 0.29 ENSDART00000181472
si:dkey-16p21.7
chr15_-_20939579 0.29 ENSDART00000152371
ubiquitin specific peptidase 2a
chr16_+_45571956 0.28 ENSDART00000143867
synaptic Ras GTPase activating protein 1b
chr7_-_4036875 0.28 ENSDART00000165021
NDRG family member 2
chr6_+_39506043 0.28 ENSDART00000086260

chr22_+_10759113 0.28 ENSDART00000045303
transmembrane protease, serine 9
chr3_+_46724528 0.28 ENSDART00000181358
phosphodiesterase 4A, cAMP-specific
chr19_-_8604429 0.27 ENSDART00000151165
tripartite motif containing 46b
chr16_-_17258111 0.27 ENSDART00000079497
EMG1 N1-specific pseudouridine methyltransferase
chr19_+_9790806 0.26 ENSDART00000155948
calcium channel, voltage-dependent, gamma subunit 6a
chr20_-_7992496 0.26 ENSDART00000145521
phospholipid phosphatase 3
chr25_-_35599887 0.25 ENSDART00000153827
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr15_+_29123031 0.25 ENSDART00000133988
ENSDART00000060030
zgc:101731
chr8_-_33381430 0.25 ENSDART00000190019
LIM homeobox transcription factor 1, beta b
chr4_+_17310143 0.25 ENSDART00000004717
insulin-like growth factor 1
chr21_+_5993188 0.25 ENSDART00000048399
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr3_-_57425961 0.25 ENSDART00000033716
suppressor of cytokine signaling 3a
chr18_+_8346920 0.25 ENSDART00000083421
carnitine palmitoyltransferase 1B (muscle)
chr20_+_30725778 0.25 ENSDART00000062532
NHS-like 1b
chr4_+_7888047 0.24 ENSDART00000104676
calcium/calmodulin-dependent protein kinase 1Da
chr15_-_14469704 0.24 ENSDART00000185077
numb homolog (Drosophila)-like
chr12_-_7824291 0.24 ENSDART00000148673
ENSDART00000149453
ankyrin 3b
chr10_-_25852517 0.24 ENSDART00000191551
transient receptor potential cation channel, subfamily C, member 4a
chr10_-_5053589 0.24 ENSDART00000193579
transmembrane protein 150C
chr4_+_11384891 0.24 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
piccolo presynaptic cytomatrix protein a
chr20_-_14012859 0.23 ENSDART00000152429
si:ch211-22i13.2
chr7_+_15266093 0.23 ENSDART00000124676
synaptic vesicle glycoprotein 2Ba
chr3_-_30061985 0.22 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr8_+_43056153 0.22 ENSDART00000186377
prion protein a
chr5_+_53479576 0.21 ENSDART00000099616
ENSDART00000169169

chr6_+_23010242 0.21 ENSDART00000113116
polymerase (DNA directed), gamma 2, accessory subunit
chr15_-_3976035 0.21 ENSDART00000168061
si:ch73-309g22.1
chr20_+_26947800 0.21 ENSDART00000062066
si:dkey-177p2.6
chr13_-_44285793 0.21 ENSDART00000167383

chr13_-_15986871 0.20 ENSDART00000189394
IKAROS family zinc finger 1 (Ikaros)
chr7_-_71829649 0.20 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr20_+_11731039 0.20 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
chr6_+_9204099 0.19 ENSDART00000150167
ENSDART00000115394
T-box 19
chr24_+_18299175 0.19 ENSDART00000140994
thiamin pyrophosphokinase 1
chr1_+_2112726 0.19 ENSDART00000131714
ENSDART00000138396
muscleblind-like splicing regulator 2
chr25_+_3328487 0.18 ENSDART00000181143
lactate dehydrogenase Bb
chr24_+_21346796 0.18 ENSDART00000126519
shisa family member 2b
chr18_-_7539469 0.18 ENSDART00000101296
si:dkey-30c15.2
chr3_+_6469754 0.18 ENSDART00000185809
nucleoporin 85
chr14_+_18782610 0.17 ENSDART00000164468
si:ch211-111e20.1
chr2_-_24269911 0.17 ENSDART00000099532
myosin heavy chain 7
chr10_+_7182168 0.17 ENSDART00000172766
pleckstrin and Sec7 domain containing 3, like
chr2_-_32505091 0.16 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr4_+_50261086 0.16 ENSDART00000140833
si:dkey-16p6.1
chr16_-_383664 0.16 ENSDART00000051693
iroquois homeobox 4a
chr24_-_26485098 0.15 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr14_-_5677979 0.15 ENSDART00000182156
T cell leukemia homeobox 2
chr23_-_35649000 0.15 ENSDART00000053310
transmembrane protein 18
chr11_+_23760470 0.14 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr17_-_25563847 0.14 ENSDART00000040032
reticulon 4 interacting protein 1
chr10_+_7182423 0.14 ENSDART00000186788
pleckstrin and Sec7 domain containing 3, like
chr16_+_3004422 0.14 ENSDART00000189969

chr6_-_8407406 0.13 ENSDART00000151355
prostaglandin E receptor 1a (subtype EP1)
chr13_-_43108693 0.13 ENSDART00000164439
si:ch211-106f21.1
chr2_-_24270062 0.13 ENSDART00000192445
myosin heavy chain 7
chr16_-_22006996 0.13 ENSDART00000116114
si:dkey-71b5.7
chr6_-_46403475 0.13 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr20_-_23842631 0.13 ENSDART00000153079
si:dkey-15j16.3
chr17_-_26610814 0.13 ENSDART00000133402
ENSDART00000016608
mitochondrial ribosomal protein L57
chr11_-_2277081 0.13 ENSDART00000109026
zinc finger protein 740a
chr18_-_215698 0.12 ENSDART00000147430
threonyl-tRNA synthetase-like 2
chr2_-_13886842 0.12 ENSDART00000187203

chr23_+_32011768 0.12 ENSDART00000053509
pleiomorphic adenoma gene X
chr4_+_29703166 0.12 ENSDART00000132876
si:ch211-214c20.1
chr1_+_45323400 0.12 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr4_+_76441823 0.12 ENSDART00000163932
si:dkey-16p6.1
chr4_+_19127973 0.12 ENSDART00000136611
si:dkey-21o22.2
chr23_-_31266586 0.12 ENSDART00000139746
si:dkey-261l7.2
chr17_+_8183393 0.12 ENSDART00000155957
tubby like protein 4b
chr20_-_32110882 0.11 ENSDART00000030324
glutamate receptor, metabotropic 1a
chr12_+_29054907 0.11 ENSDART00000152936
gamma-aminobutyric acid (GABA) A receptor, zeta
chr12_-_46228023 0.11 ENSDART00000153455
si:ch211-226h7.6
chr23_+_27652906 0.11 ENSDART00000077931
wingless-type MMTV integration site family, member 1
chr14_-_1963369 0.11 ENSDART00000125521
protocadherin 2 gamma 5
chr1_+_58981985 0.11 ENSDART00000170646
ENSDART00000171055
THUMP domain containing 1
chr5_-_21065094 0.11 ENSDART00000143785
si:dkey-13n15.2
chr5_+_61476014 0.11 ENSDART00000050906
leucine-rich repeats and WD repeat domain containing 1
chr14_-_2217285 0.10 ENSDART00000157949
ENSDART00000166150
ENSDART00000054891
ENSDART00000183268
protocadherin 2 alpha b2
protocadherin 2 alpha b2
chr18_+_43183749 0.10 ENSDART00000151166
nectin cell adhesion molecule 1b
chr24_-_25787501 0.10 ENSDART00000015628
kelch-like family member 24b
chr21_+_15295685 0.09 ENSDART00000135603

chr4_-_71294485 0.09 ENSDART00000162174
si:ch211-205a14.1
chr23_+_4646194 0.09 ENSDART00000092344

chr14_+_2243 0.09 ENSDART00000191193
cytokine like 1
chr4_-_49582108 0.08 ENSDART00000154999
si:dkey-159n16.2
chr10_+_24445698 0.07 ENSDART00000146370
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr8_-_27656765 0.07 ENSDART00000078491
Moloney leukemia virus 10b, tandem duplicate 2
chr15_-_41749364 0.07 ENSDART00000155464
finTRIM family, member 73
chr22_+_9922301 0.07 ENSDART00000105924
bloody fingers
chr12_+_49125510 0.06 ENSDART00000185804

chr24_+_9003998 0.06 ENSDART00000179656
ENSDART00000191314

chr21_+_28535203 0.06 ENSDART00000184950

chr6_+_15762647 0.06 ENSDART00000127133
ENSDART00000128939
IQ motif containing with AAA domain 1
chr4_+_50260361 0.05 ENSDART00000166894
si:dkey-16p6.1
chr1_+_26445615 0.05 ENSDART00000180810
GTPase activating protein (SH3 domain) binding protein 2
chr5_+_37890521 0.05 ENSDART00000140207
transmembrane protease, serine 4b
chr19_+_12350069 0.05 ENSDART00000052240
proteasome (prosome, macropain) assembly chaperone 2
chr6_-_55354004 0.04 ENSDART00000165911
PDX1 C-terminal inhibiting factor 1
chr6_-_13308813 0.04 ENSDART00000065372
potassium inwardly-rectifying channel, subfamily J, member 3b
chr17_+_51682429 0.03 ENSDART00000004379
nucleolar protein 10
chr12_+_16168342 0.02 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr6_+_46406565 0.02 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
polybromo 1, like
chr21_+_349091 0.02 ENSDART00000183693
zinc finger protein 462
chr15_-_41458613 0.02 ENSDART00000141496
NLR family CARD domain containing 9
chr15_-_37674120 0.02 ENSDART00000059568
si:ch211-137j23.6
chr8_-_28655338 0.02 ENSDART00000017440
melanocortin 3 receptor
chr10_+_44956660 0.02 ENSDART00000169225
ENSDART00000189298
interleukin 1, beta
chr18_-_3103827 0.01 ENSDART00000165048
adipogenesis associated, Mth938 domain containing
chr1_-_57172294 0.01 ENSDART00000063774
Rac family small GTPase 1, like
chr17_-_27382826 0.01 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
chr21_+_15312542 0.01 ENSDART00000144308
si:dkey-11o15.5
chr13_+_43650632 0.01 ENSDART00000141024
zinc finger, FYVE domain containing 21
chr5_-_34185115 0.01 ENSDART00000192771
fibrinogen C domain containing 1
chr24_+_39614853 0.01 ENSDART00000165138

chr1_+_26444986 0.00 ENSDART00000046376
GTPase activating protein (SH3 domain) binding protein 2
chr11_-_13611132 0.00 ENSDART00000113055
si:ch211-1a19.2
chr14_-_15699528 0.00 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr15_-_41333064 0.00 ENSDART00000144678
si:dkey-121n8.7
chr13_+_31479814 0.00 ENSDART00000148112
leucine rich repeat containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of gcm2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.9 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 0.5 GO:0002369 T cell cytokine production(GO:0002369)
0.2 1.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.8 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.1 0.3 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.3 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.8 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.6 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0070571 posterior lateral line neuromast hair cell development(GO:0035677) negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.4 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 1.5 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 1.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.9 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.4 GO:0021986 habenula development(GO:0021986)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:1990798 pancreas regeneration(GO:1990798)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0030975 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.1 0.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation