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PRJNA195909:zebrafish embryo and larva development

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Results for gata3

Z-value: 1.08

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Transcription factors associated with gata3

Gene Symbol Gene ID Gene Info
ENSDARG00000016526 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata3dr11_v1_chr4_-_25064510_25064510-0.265.0e-01Click!

Activity profile of gata3 motif

Sorted Z-values of gata3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_13382852 2.27 ENSDART00000166318
diacylglycerol lipase, alpha
chr16_-_35532937 2.16 ENSDART00000193209
CTP synthase 1b
chr11_-_40457325 2.01 ENSDART00000128442
tumor necrosis factor receptor superfamily, member 1B
chr8_-_6825588 1.28 ENSDART00000135834
dedicator of cytokinesis 5
chr9_-_35557397 1.21 ENSDART00000100681
neural cell adhesion molecule 2
chr4_-_16628801 1.20 ENSDART00000040708
ENSDART00000064009
caprin family member 2
chr23_-_41762956 1.18 ENSDART00000128302
serine/threonine kinase 35
chr22_-_3299355 1.16 ENSDART00000190993
si:zfos-943e10.1
chr15_+_31735931 1.01 ENSDART00000185681
ENSDART00000149137
relaxin/insulin-like family peptide receptor 2b
chr5_+_8964926 0.99 ENSDART00000091397
ENSDART00000164535
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
chr6_+_2174082 0.96 ENSDART00000073936
activin A receptor type 1Bb
chr22_+_21398508 0.91 ENSDART00000089408
ENSDART00000186091
Src homology 2 domain containing transforming protein D, b
chr5_+_44654535 0.84 ENSDART00000182190
ENSDART00000181872
death-associated protein kinase 1
chr23_+_35426404 0.81 ENSDART00000164658
si:ch211-225h24.2
chr21_-_3844322 0.80 ENSDART00000166652
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr5_-_3960161 0.77 ENSDART00000111453
myosin XIX
chr2_-_42705284 0.76 ENSDART00000187160
myosin X
chr1_-_14258409 0.76 ENSDART00000079359
phosphodiesterase 5A, cGMP-specific, a
chr12_+_48581588 0.75 ENSDART00000114996

chr5_+_44655148 0.73 ENSDART00000124059
death-associated protein kinase 1
chr25_+_1335530 0.71 ENSDART00000090803
fem-1 homolog b (C. elegans)
chr10_-_31175744 0.69 ENSDART00000191728
pbx/knotted 1 homeobox 2
chr23_-_41762797 0.66 ENSDART00000186564
serine/threonine kinase 35
chr23_-_28423222 0.65 ENSDART00000182058
complement component 1, q subcomponent-like 4
chr20_-_34754617 0.63 ENSDART00000148066
zinc finger protein 395b
chr17_-_5732299 0.62 ENSDART00000017244
XK, Kell blood group complex subunit-related family, member 6a
chr21_-_7940043 0.61 ENSDART00000099733
ENSDART00000136671
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr3_-_40768548 0.59 ENSDART00000004923
SMAD specific E3 ubiquitin protein ligase 1
chr21_-_41369539 0.59 ENSDART00000187546
cytoplasmic polyadenylation element binding protein 4b
chr3_+_51684963 0.57 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
BAI1-associated protein 2a
chr12_+_38770654 0.57 ENSDART00000155367
kinesin family member 19
chr22_+_21549419 0.55 ENSDART00000139411
phospholipid phosphatase 2b
chr18_+_35229115 0.55 ENSDART00000129624
ENSDART00000184596
transforming growth factor beta regulator 1
chr1_+_1941031 0.54 ENSDART00000110331
si:ch211-132g1.7
chr16_-_16649764 0.54 ENSDART00000014439
tenascin XBa
chr1_-_33645967 0.49 ENSDART00000192758
claudin g
chr10_+_37182626 0.49 ENSDART00000137636
kinase suppressor of ras 1a
chr20_+_22130284 0.49 ENSDART00000025575
clock circadian regulator a
chr10_-_2527342 0.49 ENSDART00000184168

chr25_+_33063762 0.48 ENSDART00000189974
talin 2b
chr7_-_48173440 0.46 ENSDART00000124075
metastasis suppressor 1-like b
chr8_-_22698651 0.46 ENSDART00000181411
IQ motif and Sec7 domain 2a
chr24_-_2381143 0.46 ENSDART00000144307
ras responsive element binding protein 1a
chr18_+_44769211 0.45 ENSDART00000177181
ilvB (bacterial acetolactate synthase)-like
chr13_+_20524921 0.45 ENSDART00000081385
coiled-coil domain containing 172
chr22_-_3299100 0.42 ENSDART00000160305
si:zfos-943e10.1
chr20_+_13781779 0.41 ENSDART00000142999
ENSDART00000152471
lysophosphatidylglycerol acyltransferase 1
chr25_+_11389220 0.41 ENSDART00000187787
si:ch73-141f14.1
chr11_+_13424116 0.39 ENSDART00000125563
homer scaffolding protein 3b
chr1_-_55238610 0.39 ENSDART00000110818

chr15_+_30126971 0.39 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr9_+_44304980 0.39 ENSDART00000147990
sperm specific antigen 2
chr18_-_25051846 0.39 ENSDART00000013082
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr17_+_23554932 0.39 ENSDART00000135814
pantothenate kinase 1a
chr15_-_9294929 0.39 ENSDART00000155717
si:ch211-261a10.5
chr20_-_48061351 0.38 ENSDART00000164962
prolyl endopeptidase
chr10_-_10018120 0.37 ENSDART00000132375
spermatid perinuclear RNA binding protein
chr7_-_13884610 0.37 ENSDART00000006897
retinaldehyde binding protein 1a
chr9_+_24192370 0.37 ENSDART00000003482
serine/threonine kinase 17b (apoptosis-inducing)
chr24_-_29822913 0.37 ENSDART00000160929
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr20_+_35445462 0.36 ENSDART00000124497
tudor domain containing 6
chr11_-_36020005 0.36 ENSDART00000031993
inositol 1,4,5-trisphosphate receptor, type 1b
chr6_+_37623693 0.36 ENSDART00000144812
ENSDART00000182709
tubulin, gamma complex associated protein 5
chr19_+_19989380 0.35 ENSDART00000142841
oxysterol binding protein-like 3a
chr18_-_22753637 0.34 ENSDART00000181589
ENSDART00000009912
heat shock transcription factor 4
chr10_+_9595575 0.34 ENSDART00000091780
ENSDART00000184287
ring finger and CCCH-type domains 2
chr22_-_16270462 0.33 ENSDART00000105681
cell division cycle 14Ab
chr13_+_31648271 0.32 ENSDART00000006648
MNAT CDK-activating kinase assembly factor 1
chr8_-_8446668 0.32 ENSDART00000132700
cyclin-dependent kinase 16
chr15_-_34866219 0.31 ENSDART00000099723
SH3-binding domain protein 5-like, a
chr2_+_42872661 0.31 ENSDART00000036979
EFR3 homolog A (S. cerevisiae)
chr20_+_35085224 0.31 ENSDART00000040456
CDC42 binding protein kinase alpha (DMPK-like) b
chr1_+_46493944 0.31 ENSDART00000114083
mcf.2 cell line derived transforming sequence-like a
chr6_+_45346808 0.30 ENSDART00000186327

chr6_-_49159207 0.30 ENSDART00000041942
tetraspanin 2a
chr3_-_13146631 0.30 ENSDART00000172460
protein kinase, cAMP-dependent, regulatory, type I, beta
chr15_-_5624361 0.30 ENSDART00000176446
ENSDART00000114410
WD repeat domain 62
chr20_-_51559419 0.29 ENSDART00000065231
dispatched homolog 1 (Drosophila)
chr12_+_19958845 0.29 ENSDART00000193248
excision repair cross-complementation group 4
chr22_+_997838 0.29 ENSDART00000149743
peroxisome proliferator-activated receptor delta a
chr21_-_41369370 0.28 ENSDART00000159290
cytoplasmic polyadenylation element binding protein 4b
chr15_-_16704417 0.28 ENSDART00000155163
calneuron 1
chr9_-_1639884 0.28 ENSDART00000062850
ENSDART00000150947
alkylglycerone phosphate synthase
chr20_-_15922986 0.28 ENSDART00000189421
family with sequence similarity 20, member B (H. sapiens)
chr25_+_32496723 0.28 ENSDART00000087978
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr10_+_37181780 0.28 ENSDART00000187625
kinase suppressor of ras 1a
chr18_-_20822045 0.28 ENSDART00000100743
cortactin binding protein 2
chr21_+_33249478 0.28 ENSDART00000169972
si:ch211-151g22.1
chr14_-_35892767 0.28 ENSDART00000052648
transmembrane protein 144b
chr17_+_22587356 0.28 ENSDART00000157328
baculoviral IAP repeat containing 6
chr4_+_4889257 0.27 ENSDART00000175651
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr25_+_32496877 0.26 ENSDART00000132698
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr7_+_71955486 0.26 ENSDART00000189349
Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA.
chr23_+_34321237 0.26 ENSDART00000173272
plexin A1a
chr9_+_45605410 0.26 ENSDART00000136444
ENSDART00000007189
ENSDART00000158713
ENSDART00000182671
TNF receptor-associated factor 3 interacting protein 1
chr16_-_52736549 0.25 ENSDART00000146607
antizyme inhibitor 1a
chr8_-_31417139 0.25 ENSDART00000180204
zinc finger protein 131
chr4_-_19883985 0.25 ENSDART00000014440
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr7_+_34296789 0.25 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_874888 0.25 ENSDART00000007206
eomesodermin homolog a
chr3_+_15394428 0.24 ENSDART00000133168
ataxin 2-like
chr17_-_14523722 0.24 ENSDART00000024726
dishevelled associated activator of morphogenesis 1a
chr8_+_11325310 0.24 ENSDART00000142577
frataxin
chr18_+_20560616 0.24 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr19_+_7552699 0.24 ENSDART00000180788
ENSDART00000115058
pre-B-cell leukemia homeobox interacting protein 1a
chr17_+_49500820 0.24 ENSDART00000170306
apoptosis resistant E3 ubiquitin protein ligase 1
chr2_+_54755172 0.24 ENSDART00000097864
ankyrin repeat domain 12
chr19_-_977849 0.24 ENSDART00000172303

chr8_-_33154677 0.23 ENSDART00000133300
zinc finger and BTB domain containing 34
chr14_+_44545092 0.23 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr10_-_10018794 0.23 ENSDART00000130734
spermatid perinuclear RNA binding protein
chr6_-_40446536 0.23 ENSDART00000153466
TatD DNase domain containing 2
chr4_-_21466825 0.23 ENSDART00000066897
PRKC, apoptosis, WT1, regulator
chr10_+_44581378 0.23 ENSDART00000190331
seizure related 6 homolog (mouse)-like
chr17_-_26604549 0.23 ENSDART00000174773
family with sequence similarity 149, member B1
chr8_+_12951155 0.23 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr20_-_52939501 0.22 ENSDART00000166508
farnesyl-diphosphate farnesyltransferase 1
chr2_+_51796441 0.22 ENSDART00000165151
crystallin, gamma N1
chr23_-_20010579 0.22 ENSDART00000089999
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr20_+_40739964 0.22 ENSDART00000061251
ENSDART00000156669
connexin 28.1
chr11_+_13423776 0.22 ENSDART00000102553
homer scaffolding protein 3b
chr16_+_31511739 0.22 ENSDART00000049420
N-myc downstream regulated 1b
chr2_+_29997043 0.22 ENSDART00000139566
ENSDART00000151848
RNA binding motif protein 33b
chr8_+_26859639 0.22 ENSDART00000133440
PR domain containing 2, with ZNF domain a
chr3_+_23247325 0.22 ENSDART00000114190
protein phosphatase 1, regulatory subunit 9Ba
chr5_-_18513950 0.22 ENSDART00000145878
si:dkey-215k6.1
chr1_-_21321482 0.22 ENSDART00000054440
transmembrane protein 144a
chr8_+_9699111 0.22 ENSDART00000111853
GRIP1 associated protein 1
chr21_-_34261677 0.22 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr12_-_23320266 0.21 ENSDART00000181711
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr14_+_20156477 0.21 ENSDART00000123434
fragile X mental retardation 1
chr24_-_26885897 0.21 ENSDART00000180512
fibronectin type III domain containing 3Bb
chr4_-_19884440 0.21 ENSDART00000182979
ENSDART00000105967
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr15_-_33304133 0.21 ENSDART00000186092
neurobeachin b
chr16_+_48714048 0.20 ENSDART00000148709
ENSDART00000150121
bromodomain containing 2b
chr18_+_14307059 0.20 ENSDART00000186558
zgc:173742
chr12_+_28986308 0.20 ENSDART00000153178
si:rp71-1c10.8
chr9_+_50007556 0.20 ENSDART00000175587
solute carrier family 38, member 11
chr18_+_3169579 0.20 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr20_-_165818 0.20 ENSDART00000123860
si:ch211-241j12.3
chr6_-_31827597 0.20 ENSDART00000159400
receptor tyrosine kinase-like orphan receptor 1
chr2_+_37207461 0.20 ENSDART00000138952
ENSDART00000132856
ENSDART00000137272
ENSDART00000143468
apolipoprotein Da, duplicate 2
chr16_-_5873866 0.20 ENSDART00000136936
trafficking protein, kinesin binding 1a
chr21_-_41588129 0.19 ENSDART00000164125
creb3 regulatory factor
chr22_+_15633013 0.19 ENSDART00000188095
ENSDART00000048763

chr4_-_72638972 0.19 ENSDART00000193312

chr7_+_17816006 0.19 ENSDART00000080834
echinoderm microtubule associated protein like 3
chr11_+_36989696 0.18 ENSDART00000045888
transketolase a
chr8_-_410199 0.18 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr8_-_49701904 0.18 ENSDART00000142115
FERM domain containing 3
chr2_-_38992304 0.18 ENSDART00000114085
ENSDART00000146812
si:ch211-119o8.6
chr19_-_36675023 0.18 ENSDART00000132471
CUB and Sushi multiple domains 2
chr16_-_26132122 0.18 ENSDART00000157787
lipase, hormone-sensitive b
chr20_+_6535438 0.18 ENSDART00000145763
si:ch211-191a24.4
chr15_+_44201056 0.18 ENSDART00000162433
ENSDART00000148336

chr13_-_46991577 0.18 ENSDART00000114748
vasoactive intestinal peptide
chr11_-_42230491 0.18 ENSDART00000164423

chr23_+_2542158 0.17 ENSDART00000182197

chr3_-_21137362 0.17 ENSDART00000104051
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr17_+_6535694 0.17 ENSDART00000191681
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr6_-_15604157 0.17 ENSDART00000141597
leucine rich repeat (in FLII) interacting protein 1b
chr7_+_72882446 0.17 ENSDART00000131113
ENSDART00000174223
adhesion G protein-coupled receptor L3
chr6_-_6295513 0.17 ENSDART00000092172
mitochondrial translational initiation factor 2
chr11_-_13152215 0.17 ENSDART00000160989
ENSDART00000158239
ELOVL fatty acid elongase 1b
chr3_-_2623176 0.17 ENSDART00000179792
ENSDART00000123512
si:dkey-217f16.6
chr11_-_2270069 0.17 ENSDART00000189005
zinc finger protein 740a
chr10_-_9192450 0.17 ENSDART00000139783
si:dkeyp-41f9.4
chr4_-_14315855 0.17 ENSDART00000133325
neural EGFL like 2b
chr4_-_20135919 0.17 ENSDART00000172230
centrosomal protein 83
chr10_+_1849874 0.17 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr18_+_44769027 0.17 ENSDART00000145190
ilvB (bacterial acetolactate synthase)-like
chr13_+_33462232 0.17 ENSDART00000177841
zgc:136302
chr3_-_34717882 0.17 ENSDART00000151127
thyroid hormone receptor alpha a
chr17_-_17447899 0.16 ENSDART00000156928
ENSDART00000109034
neurexin 3a
chr10_-_35186310 0.16 ENSDART00000127805
POM121 transmembrane nucleoporin
chr19_+_19988869 0.16 ENSDART00000151024
oxysterol binding protein-like 3a
chr16_-_33097398 0.16 ENSDART00000166617
dopey family member 1
chr21_-_7781555 0.16 ENSDART00000084380
ENSDART00000189131
angiogenic factor with G patch and FHA domains 1
chr3_+_53352018 0.16 ENSDART00000082715
calmodulin regulated spectrin-associated protein family, member 3
chr8_+_41048501 0.16 ENSDART00000123288
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr23_-_32334208 0.16 ENSDART00000053472
ring finger protein 41
chr1_-_53988017 0.16 ENSDART00000003097
si:ch211-133l11.10
chr8_-_3716734 0.16 ENSDART00000172966
BICD family like cargo adaptor 1
chr2_-_41964402 0.16 ENSDART00000131278
si:dkey-97a13.6
chr8_-_410728 0.16 ENSDART00000151255
tripartite motif containing 36
chr6_+_37754763 0.16 ENSDART00000110770
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr16_+_35535171 0.16 ENSDART00000167001
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr15_+_29025090 0.16 ENSDART00000131755
si:ch211-137a8.2
chr9_-_51370293 0.16 ENSDART00000084806
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr23_-_18415872 0.16 ENSDART00000135430
family with sequence similarity 120C
chr6_+_30491129 0.16 ENSDART00000088142
WWC family member 3
chr15_-_25099679 0.16 ENSDART00000154628
refilin B
chr12_-_22238004 0.16 ENSDART00000038310
ORMDL sphingolipid biosynthesis regulator 3
chr19_-_38419575 0.15 ENSDART00000087639
small ArfGAP2
chr24_-_7587401 0.15 ENSDART00000093163
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr20_-_164300 0.15 ENSDART00000183354
si:ch211-241j12.3
chr14_+_44805649 0.15 ENSDART00000180361
solute carrier family 30 (zinc transporter), member 9
chr8_+_19621511 0.15 ENSDART00000017128
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr8_-_8446430 0.15 ENSDART00000137382
cyclin-dependent kinase 16
chr5_+_13521081 0.15 ENSDART00000171975
si:ch211-230g14.6

Network of associatons between targets according to the STRING database.

First level regulatory network of gata3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.5 2.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.4 1.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.3 1.1 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.2 0.6 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 2.0 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.3 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.2 GO:1903011 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 0.2 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0043084 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.2 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.1 GO:0005991 trehalose metabolic process(GO:0005991)
0.0 0.2 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.0 0.3 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.2 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.3 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.3 GO:0090660 regulation of microtubule polymerization(GO:0031113) cerebrospinal fluid circulation(GO:0090660)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.3 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 1.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.5 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.0 0.2 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.3 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 1.0 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.3 GO:0060213 positive regulation of mRNA 3'-end processing(GO:0031442) regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.3 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.4 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.0 GO:0033210 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 1.9 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 1.1 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0090133 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719) negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.0 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.0 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0097268 cytoophidium(GO:0097268)
0.2 0.6 GO:0005948 acetolactate synthase complex(GO:0005948)
0.1 0.4 GO:0033391 chromatoid body(GO:0033391)
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.2 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0003883 CTP synthase activity(GO:0003883)
0.2 2.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 0.6 GO:0003984 acetolactate synthase activity(GO:0003984)
0.2 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.8 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.1 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 1.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.1 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.4 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.1 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.0 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.0 GO:0033204 ribonuclease P RNA binding(GO:0033204)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA