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PRJNA195909:zebrafish embryo and larva development

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Results for gata1a+gata2b

Z-value: 0.35

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Transcription factors associated with gata1a+gata2b

Gene Symbol Gene ID Gene Info
ENSDARG00000009094 GATA binding protein 2b
ENSDARG00000013477 GATA binding protein 1a
ENSDARG00000117116 GATA binding protein 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata2bdr11_v1_chr6_+_40794015_407940150.809.2e-03Click!
gata1adr11_v1_chr11_-_25418856_254188560.255.1e-01Click!

Activity profile of gata1a+gata2b motif

Sorted Z-values of gata1a+gata2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_31175744 0.51 ENSDART00000191728
pbx/knotted 1 homeobox 2
chr21_+_24287403 0.34 ENSDART00000111169
cell adhesion molecule 1a
chr19_-_32710922 0.33 ENSDART00000004034
hippocalcin
chr19_+_12444943 0.28 ENSDART00000135706
low density lipoprotein receptor class A domain containing 4a
chr12_-_5505205 0.27 ENSDART00000092319
ABI family, member 3b
chr16_-_35532937 0.24 ENSDART00000193209
CTP synthase 1b
chr22_+_21398508 0.22 ENSDART00000089408
ENSDART00000186091
Src homology 2 domain containing transforming protein D, b
chr22_+_15507218 0.22 ENSDART00000125450
glypican 1a
chr6_-_49159207 0.20 ENSDART00000041942
tetraspanin 2a
chr18_-_22753637 0.14 ENSDART00000181589
ENSDART00000009912
heat shock transcription factor 4
chr8_-_6825588 0.11 ENSDART00000135834
dedicator of cytokinesis 5
chr11_-_40457325 0.11 ENSDART00000128442
tumor necrosis factor receptor superfamily, member 1B
chr4_-_1360495 0.09 ENSDART00000164623
pleiotrophin
chr21_+_43561650 0.02 ENSDART00000085071
G protein-coupled receptor 185 a
chr22_+_635813 0.01 ENSDART00000179067

chr17_+_5768608 0.00 ENSDART00000157039
retinitis pigmentosa 1-like 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1a+gata2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.