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PRJNA195909:zebrafish embryo and larva development
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Results for foxn1
Z-value: 1.63
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Transcription factors associated with foxn1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| foxn1 | dr11_v1_chr15_-_28161224_28161224 | 0.70 | 3.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr23_+_19590006 Show fit | 3.03 |
ENSDART00000021231
|
sarcolemma associated protein b |
|
| chr6_+_40992409 Show fit | 2.08 |
ENSDART00000151419
|
transforming growth factor, alpha |
|
| chr20_-_6196989 Show fit | 1.86 |
ENSDART00000013343
|
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
|
| chr14_+_22457230 Show fit | 1.86 |
ENSDART00000019296
|
growth differentiation factor 9 |
|
| chr17_-_2584423 Show fit | 1.85 |
ENSDART00000013506
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr3_+_58472305 Show fit | 1.78 |
ENSDART00000154122
|
si:ch211-165g14.1 |
|
| chr21_+_4256291 Show fit | 1.74 |
ENSDART00000148138
|
leucine rich repeat containing 8 VRAC subunit Aa |
|
| chr18_-_1270220 Show fit | 1.74 |
ENSDART00000193754
|
UDP glucuronosyltransferase 5 family, polypeptide F1 |
|
| chr3_+_7763114 Show fit | 1.69 |
ENSDART00000057434
|
hook microtubule-tethering protein 2 |
|
| chr11_+_18183220 Show fit | 1.65 |
ENSDART00000113468
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of foxn1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.2 | 2.1 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273) |
| 0.1 | 2.1 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.6 | 1.9 | GO:0030237 | female sex determination(GO:0030237) |
| 0.2 | 1.9 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.1 | 1.9 | GO:0090279 | regulation of calcium ion import(GO:0090279) |
| 0.1 | 1.9 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.1 | 1.8 | GO:2000344 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.0 | 1.8 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.0 | 1.8 | GO:0006865 | amino acid transport(GO:0006865) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 1.8 | GO:0005930 | axoneme(GO:0005930) |
| 0.2 | 1.6 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.2 | 1.5 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) |
| 0.0 | 1.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.1 | 1.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 1.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 1.2 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 1.2 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.0 | GO:0001217 | bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217) |
| 0.1 | 2.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 2.1 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 2.1 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 2.1 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.6 | 1.9 | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489) |
| 0.3 | 1.9 | GO:0070698 | type I activin receptor binding(GO:0070698) |
| 0.2 | 1.8 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.2 | 1.7 | GO:0016530 | metallochaperone activity(GO:0016530) |
| 0.2 | 1.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 2.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.5 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 1.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.1 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 0.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.8 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 0.7 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.7 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.1 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.1 | 1.9 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 1.5 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 1.4 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.1 | 1.3 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.0 | 1.2 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.1 | 1.1 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.0 | 1.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 1.1 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 1.0 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |