ISMARA results: foxm1

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PRJNA195909:zebrafish embryo and larva development

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Results for foxm1

Z-value: 1.53

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Transcription factors associated with foxm1

Gene Symbol	Gene ID	Gene Info
foxm1 NCBI UniProt	ENSDARG00000003200	forkhead box M1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
foxm1	dr11_v1_chr4_-_5831036_5831036	0.82	6.9e-03	Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_-_4245902 Show fit	2.57	ENSDART00000151851	gdf3 NCBI UniProt Show fit	growth differentiation factor 3
chr9_+_33216945 Show fit	2.36	ENSDART00000134029	si:ch211-125e6.12 NCBI UniProt Show fit	si:ch211-125e6.12
chr13_+_31550185 Show fit	1.62	ENSDART00000127843	ppm1aa NCBI UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr16_+_25259313 Show fit	1.57	ENSDART00000058938	fbxo32 NCBI UniProt Show fit	F-box protein 32
chr22_+_835728 Show fit	1.42	ENSDART00000003325	dennd2db NCBI UniProt Show fit	DENN/MADD domain containing 2Db
chr13_-_22961605 Show fit	1.38	ENSDART00000143112 ENSDART00000057641	tspan15 NCBI UniProt Show fit	tetraspanin 15
chr5_-_16475682 Show fit	1.28	ENSDART00000090695	piwil2 NCBI UniProt Show fit	piwi-like RNA-mediated gene silencing 2
chr10_-_32465462 Show fit	1.25	ENSDART00000134056	uvrag NCBI UniProt Show fit	UV radiation resistance associated gene
chr13_+_37653851 Show fit	1.24	ENSDART00000141988 ENSDART00000126902 ENSDART00000100352	phf3 NCBI UniProt Show fit	PHD finger protein 3
chr18_+_17534627 Show fit	1.21	ENSDART00000061007	mt2 NCBI UniProt Show fit	metallothionein 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.6	GO:1900145	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0	1.8	GO:0051604	protein maturation(GO:0051604)
0.2	1.6	GO:0040016	embryonic cleavage(GO:0040016)
0.2	1.6	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.1	1.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	1.4	GO:0051597	response to methylmercury(GO:0051597)
0.0	1.4	GO:0031101	fin regeneration(GO:0031101)
0.3	1.3	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.1	1.2	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	1.2	GO:0048264	determination of ventral identity(GO:0048264)

Showing 1 to 10 of 111 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.1	GO:0000775	chromosome, centromeric region(GO:0000775)
0.1	2.6	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	1.4	GO:0000124	SAGA complex(GO:0000124)
0.0	1.4	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3	1.3	GO:1990923	PET complex(GO:1990923)
0.0	1.3	GO:0031901	early endosome membrane(GO:0031901)
0.1	1.2	GO:0035101	FACT complex(GO:0035101)
0.1	1.2	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	1.2	GO:0000781	chromosome, telomeric region(GO:0000781)
0.1	1.0	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Showing 1 to 10 of 39 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	GO:0030145	manganese ion binding(GO:0030145)
0.0	2.6	GO:0005125	cytokine activity(GO:0005125)
0.0	1.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	1.7	GO:0003777	microtubule motor activity(GO:0003777)
0.0	1.7	GO:0042393	histone binding(GO:0042393)
0.2	1.3	GO:0034584	piRNA binding(GO:0034584)
0.1	1.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	1.2	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	1.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	1.0	GO:0070698	type I activin receptor binding(GO:0070698)

Showing 1 to 10 of 72 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	3.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.7	PID FOXO PATHWAY	FoxO family signaling
0.0	0.9	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.8	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	PID P73PATHWAY	p73 transcription factor network

Showing 1 to 10 of 20 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.6	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	0.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules

Showing 1 to 10 of 24 entries

Results for foxm1

Z-value: 1.53

Motif logo

Transcription factors associated with foxm1

Activity-expression correlation:

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: