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PRJNA195909:zebrafish embryo and larva development

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Results for foxm1

Z-value: 1.53

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Transcription factors associated with foxm1

Gene Symbol Gene ID Gene Info
ENSDARG00000003200 forkhead box M1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxm1dr11_v1_chr4_-_5831036_58310360.826.9e-03Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_4245902 2.57 ENSDART00000151851
growth differentiation factor 3
chr9_+_33216945 2.36 ENSDART00000134029
si:ch211-125e6.12
chr13_+_31550185 1.62 ENSDART00000127843
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr16_+_25259313 1.57 ENSDART00000058938
F-box protein 32
chr22_+_835728 1.42 ENSDART00000003325
DENN/MADD domain containing 2Db
chr13_-_22961605 1.38 ENSDART00000143112
ENSDART00000057641
tetraspanin 15
chr5_-_16475682 1.28 ENSDART00000090695
piwi-like RNA-mediated gene silencing 2
chr10_-_32465462 1.25 ENSDART00000134056
UV radiation resistance associated gene
chr13_+_37653851 1.24 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr18_+_17534627 1.21 ENSDART00000061007
metallothionein 2
chr16_+_25068576 1.16 ENSDART00000125838
im:7147486
chr7_+_15736230 1.09 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr22_-_17671348 1.07 ENSDART00000137995
tight junction protein 3
chr9_+_23770666 1.05 ENSDART00000182493
si:ch211-219a4.3
chr7_-_51775688 1.02 ENSDART00000149793
bone morphogenetic protein 15
chr9_+_22780901 1.01 ENSDART00000110992
ENSDART00000143972
replication timing regulatory factor 1
chr12_-_33558879 1.01 ENSDART00000161167
mbt domain containing 1
chr15_+_29393519 1.00 ENSDART00000193488
ENSDART00000112375
glycerophosphodiester phosphodiesterase domain containing 5b
chr11_-_18017918 0.99 ENSDART00000040171
glutamine-rich 1
chr11_-_18017287 0.96 ENSDART00000155443
glutamine-rich 1
chr13_-_18011168 0.95 ENSDART00000144813
membrane-associated ring finger (C3HC4) 8
chr12_+_17154655 0.95 ENSDART00000028003
ankyrin repeat domain 22
chr11_-_18107447 0.94 ENSDART00000187376
glutamine-rich 1
chr24_+_5893134 0.93 ENSDART00000077941
microtubule associated serine/threonine kinase-like
chr18_+_35128685 0.93 ENSDART00000151579
si:ch211-195m9.3
chr3_-_54607166 0.92 ENSDART00000021977
DNA (cytosine-5-)-methyltransferase 1
chr21_+_40685895 0.92 ENSDART00000017709
coiled-coil domain containing 82
chr10_+_15454745 0.89 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr18_-_20458412 0.88 ENSDART00000012241
kinesin family member 23
chr6_+_40922572 0.88 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr6_-_14040136 0.87 ENSDART00000065361
ENSDART00000179765
ets variant 5b
chr14_+_8638353 0.87 ENSDART00000163240
si:dkeyp-115e12.6
chr8_-_22558773 0.87 ENSDART00000074309
porcupine O-acyltransferase like
chr13_+_24679674 0.87 ENSDART00000033090
ENSDART00000139854
zgc:66426
chr10_-_35257458 0.86 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr5_-_38197080 0.86 ENSDART00000140708
si:ch211-284e13.9
chr4_+_5196469 0.85 ENSDART00000067386
RAD51 associated protein 1
chr4_+_65127317 0.85 ENSDART00000166475
zinc finger protein 1126
chr15_-_1001177 0.84 ENSDART00000160730
zgc:162936
chr2_-_44777592 0.83 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr11_+_44502410 0.82 ENSDART00000172998
endoplasmic reticulum oxidoreductase beta
chr10_-_35051691 0.81 ENSDART00000108670
ENSDART00000190711
SPT20 homolog, SAGA complex component
chr6_-_40922971 0.80 ENSDART00000155363
SFI1 centrin binding protein
chr7_+_55950229 0.80 ENSDART00000082780
acyl-CoA synthetase family member 3
chr14_-_30905963 0.80 ENSDART00000183543
ENSDART00000186441
si:ch211-126c2.4
chr6_-_54444929 0.80 ENSDART00000154121
Sys1 golgi trafficking protein
chr22_-_6066867 0.79 ENSDART00000142383
si:dkey-19a16.1
chr19_-_38419575 0.79 ENSDART00000087639
small ArfGAP2
chr2_+_43204919 0.78 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr17_+_32622933 0.78 ENSDART00000077418
cathepsin Ba
chr25_+_28679672 0.78 ENSDART00000139965
ENSDART00000134072
CCR4-NOT transcription complex, subunit 2
chr3_-_60589292 0.78 ENSDART00000157822
jumonji domain containing 6
chr3_+_1167026 0.77 ENSDART00000031823
ENSDART00000155340
TRIO and F-actin binding protein b
chr4_-_5691257 0.77 ENSDART00000110497
transmembrane protein 63A
chr19_+_25154066 0.77 ENSDART00000163220
si:ch211-239d6.2
chr6_+_11397269 0.76 ENSDART00000114260
SUMO1/sentrin/SMT3 specific peptidase 2
chr18_-_20458840 0.75 ENSDART00000177125
kinesin family member 23
chr11_+_6881001 0.75 ENSDART00000170331
kelch-like family member 26
chr10_+_585719 0.75 ENSDART00000180167
SMAD family member 4a
chr17_+_18810904 0.74 ENSDART00000130899
si:dkey-288a3.2
chr1_-_51038885 0.73 ENSDART00000035150
spastin
chr22_+_38935060 0.73 ENSDART00000183732
ENSDART00000130055
sirtuin 7
chr15_-_37589600 0.73 ENSDART00000154641
proline and serine rich 3
chr21_-_13856689 0.72 ENSDART00000102197
family with sequence similarity 129, member Ba
chr6_+_21536131 0.72 ENSDART00000113911
ENSDART00000188472
MICAL-like 1a
chr4_-_39110934 0.71 ENSDART00000185041
si:dkey-122c11.8
chr19_-_7832439 0.70 ENSDART00000104703
ENSDART00000132336
zinc finger protein 687b
chr15_-_23761580 0.68 ENSDART00000137918
BCL2 binding component 3
chr5_+_29726428 0.68 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr3_+_32714157 0.68 ENSDART00000131774
SET domain containing 1A
chr3_-_49138004 0.68 ENSDART00000167173
GIPC PDZ domain containing family, member 1
chr8_+_50531709 0.67 ENSDART00000193352
phosphatidylethanolamine binding protein 4
chr9_+_21259820 0.67 ENSDART00000137024
ENSDART00000132324
spindle and kinetochore associated complex subunit 3
chr14_+_22498757 0.66 ENSDART00000021657
SMYD family member 5
chr1_+_52137528 0.65 ENSDART00000007079
ENSDART00000074265
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr17_-_25630822 0.65 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr7_-_13906409 0.64 ENSDART00000062257
solute carrier family 39 (zinc transporter), member 1
chr5_-_18446483 0.64 ENSDART00000180027
si:dkey-215k6.1
chr15_+_1653779 0.64 ENSDART00000021299
NMD3 ribosome export adaptor
chr21_+_3796620 0.64 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr7_+_17933384 0.64 ENSDART00000173701
metastasis associated 1 family, member 2
chr3_-_29891218 0.64 ENSDART00000142118
solute carrier family 25, member 39
chr1_-_23268013 0.64 ENSDART00000146575
replication factor C (activator 1) 1
chr10_-_42237304 0.63 ENSDART00000140341
transcription factor 7 like 1a
chr13_+_11828516 0.63 ENSDART00000110141
suppressor of fused homolog (Drosophila)
chr10_-_244745 0.63 ENSDART00000136551
kelch-like family member 35
chr20_+_25904199 0.62 ENSDART00000016864
solute carrier family 35, member F6
chr2_+_33926911 0.62 ENSDART00000109849
ENSDART00000135884
kinesin family member 2C
chr2_-_24603325 0.62 ENSDART00000113356
CREB regulated transcription coactivator 1a
chr4_-_39111612 0.62 ENSDART00000150394
si:dkey-122c11.8
chr1_+_45839927 0.59 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr14_-_41388178 0.59 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr9_+_27876146 0.59 ENSDART00000133997
armadillo repeat containing 8
chr16_+_40131473 0.58 ENSDART00000155421
ENSDART00000134732
ENSDART00000138699
centromere protein W
si:ch211-195p4.4
chr11_+_30253968 0.58 ENSDART00000157272
ENSDART00000003475
protein phosphatase, EF-hand calcium binding domain 1
chr11_+_30254556 0.58 ENSDART00000182316
protein phosphatase, EF-hand calcium binding domain 1
chr7_-_19638319 0.57 ENSDART00000163686
si:ch211-212k18.4
chr2_+_11205795 0.57 ENSDART00000019078
LIM homeobox 8a
chr10_+_22891126 0.57 ENSDART00000057291
arrestin, beta 2a
chr12_-_23365737 0.57 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr17_-_21162821 0.56 ENSDART00000157283
abhydrolase domain containing 12
chr25_+_3868438 0.56 ENSDART00000156438
transmembrane protein 138
chr2_-_29996036 0.56 ENSDART00000020792
canopy1
chr6_+_28018390 0.55 ENSDART00000123324
ENSDART00000150915
Sin3A-associated protein a
chr18_+_11858397 0.55 ENSDART00000133762
transmembrane and tetratricopeptide repeat containing 2b
chr10_-_35052198 0.54 ENSDART00000147805
SPT20 homolog, SAGA complex component
chr7_-_4125021 0.54 ENSDART00000167182
ENSDART00000173696
zgc:55733
chr15_-_25613114 0.54 ENSDART00000182431
ENSDART00000187405
TAO kinase 1a
chr14_-_52433292 0.54 ENSDART00000164272
RE1-silencing transcription factor
chr7_-_6448182 0.54 ENSDART00000173045
si:ch1073-159d7.7
chr6_+_16949735 0.53 ENSDART00000155342
Pim proto-oncogene, serine/threonine kinase, related 13
chr3_+_53116172 0.53 ENSDART00000115117
bromodomain containing 4
chr25_-_24202576 0.53 ENSDART00000048507
UEV and lactate/malate dehyrogenase domains
chr5_+_39099380 0.53 ENSDART00000166657
BMP2 inducible kinase
chr18_-_42333428 0.53 ENSDART00000034225
contactin 5
chr16_-_31445781 0.52 ENSDART00000056551
casein kinase 2, alpha 1 polypeptide
chr1_+_19538299 0.51 ENSDART00000109416
structural maintenance of chromosomes 2
chr15_-_28587147 0.51 ENSDART00000156049
slingshot protein phosphatase 2a
chr3_+_60589157 0.51 ENSDART00000165367
methyltransferase like 23
chr5_+_27267186 0.51 ENSDART00000182238
ENSDART00000087857
unc-5 netrin receptor Db
chr13_+_33298338 0.51 ENSDART00000131892
ENSDART00000143895
IQ motif containing C
chr19_+_7759354 0.50 ENSDART00000151400
ubiquitin associated protein 2-like
chr13_+_7578111 0.50 ENSDART00000175431
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr19_-_6134802 0.50 ENSDART00000140051
capicua transcriptional repressor a
chr7_-_6444011 0.50 ENSDART00000173010
zgc:112234
chr17_+_8799661 0.50 ENSDART00000105326
tonsoku-like, DNA repair protein
chr23_+_39611688 0.49 ENSDART00000034690
OTU deubiquitinase 3
chr11_-_42418374 0.48 ENSDART00000160704
sarcolemma associated protein a
chr10_+_573667 0.48 ENSDART00000110384
SMAD family member 4a
chr1_-_55166511 0.48 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr12_+_28888975 0.47 ENSDART00000076362
phosphorylase kinase, gamma 2 (testis)
chr10_-_38243579 0.47 ENSDART00000150159
ubiquitin specific peptidase 25
chr2_+_31838442 0.47 ENSDART00000066789
STARD3 N-terminal like
chr18_+_26829086 0.46 ENSDART00000098356
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr10_+_35257651 0.46 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr25_-_35045250 0.46 ENSDART00000156508
ENSDART00000126590
zgc:114046
chr9_-_55772937 0.46 ENSDART00000159192
A kinase (PRKA) anchor protein 17A
chr22_-_22301672 0.45 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr19_-_10324182 0.45 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
U2 small nuclear RNA auxiliary factor 2b
chr7_+_52766211 0.45 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr18_+_44768829 0.45 ENSDART00000016271
ilvB (bacterial acetolactate synthase)-like
chr8_+_40210398 0.44 ENSDART00000167612
ring finger protein 34a
chr13_+_2894536 0.44 ENSDART00000183678

chr11_-_11336986 0.44 ENSDART00000016677
zgc:77929
chr19_-_11966015 0.43 ENSDART00000123409
si:ch1073-296d18.1
chr7_+_17255705 0.43 ENSDART00000053357
ENSDART00000167849
ENSDART00000165833
novel immune-type receptor 9
si:ch73-46n24.1
chr3_+_37112693 0.43 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
PSMC3 interacting protein
chr15_-_23692359 0.42 ENSDART00000141618
excision repair cross-complementation group 2
chr14_-_22015232 0.42 ENSDART00000137795
structure specific recognition protein 1a
chr14_+_52481288 0.42 ENSDART00000169164
ENSDART00000159297
transcription elongation regulator 1a (CA150)
chr3_+_1107102 0.42 ENSDART00000092690
sterol regulatory element binding transcription factor 2
chr11_+_45153104 0.41 ENSDART00000159204
ENSDART00000177585
thymidine kinase 1, soluble
chr20_-_22798794 0.41 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr7_+_30282389 0.40 ENSDART00000108782
RNA polymerase II subunit M
chr7_-_19642417 0.40 ENSDART00000160936
si:ch211-212k18.4
chr13_+_10023256 0.40 ENSDART00000110035
S1 RNA binding domain 1
chr15_+_23534126 0.39 ENSDART00000152320
si:dkey-182i3.10
chr19_+_4139065 0.38 ENSDART00000172524
si:dkey-218f9.10
chr4_+_9011825 0.38 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr11_-_2250767 0.38 ENSDART00000018131
heterogeneous nuclear ribonucleoprotein A1a
chr12_-_9516981 0.38 ENSDART00000106285
si:ch211-207i20.3
chr3_-_50118140 0.38 ENSDART00000131913
hepatocyte growth factor-regulated tyrosine kinase substrate
chr8_+_23147218 0.38 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr6_+_40523370 0.38 ENSDART00000033819
protein kinase C, delta a
chr16_+_1100559 0.37 ENSDART00000092657
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr20_+_9124369 0.37 ENSDART00000064150
si:ch211-59d15.9
chr1_-_18585046 0.37 ENSDART00000147228
family with sequence similarity 114, member A1
chr9_+_2522797 0.36 ENSDART00000186786
ENSDART00000147034
G protein-coupled receptor 155a
chr3_-_13461361 0.36 ENSDART00000080807
F-box and WD repeat domain containing 9
chr21_-_23046606 0.36 ENSDART00000016167
zw10 kinetochore protein
chr18_+_41560822 0.36 ENSDART00000158503
bromodomain adjacent to zinc finger domain, 1B
chr16_+_46410520 0.35 ENSDART00000131072
rapunzel 2
chr3_-_13461056 0.35 ENSDART00000137678
F-box and WD repeat domain containing 9
chr5_-_23596339 0.34 ENSDART00000024815
family with sequence similarity 76, member B
chr7_+_38811800 0.34 ENSDART00000052322
zgc:110699
chr17_-_11439815 0.33 ENSDART00000130105
proteasome subunit alpha 3
chr14_-_4177311 0.33 ENSDART00000128129
si:dkey-185e18.7
chr17_+_23975762 0.33 ENSDART00000155941
exportin 1 (CRM1 homolog, yeast) b
chr25_-_20730800 0.33 ENSDART00000172170
si:ch211-127m7.2
chr8_-_18211605 0.33 ENSDART00000114177

chr17_-_8656155 0.33 ENSDART00000148990
C-terminal binding protein 2a
chr8_-_21071476 0.32 ENSDART00000184184
ENSDART00000100288
zgc:112962
chr13_+_12761707 0.32 ENSDART00000015127
zgc:100846
chr11_-_24347644 0.31 ENSDART00000089777
si:ch211-15p9.2
chr25_+_36045072 0.31 ENSDART00000126326
RPGRIP1-like
chr7_-_50604626 0.31 ENSDART00000073903
ENSDART00000174031
CREB regulated transcription coactivator 3
chr5_-_13251907 0.31 ENSDART00000176774
ENSDART00000030553
DNA topoisomerase III beta
chr15_-_28082310 0.31 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr5_-_51902935 0.31 ENSDART00000182160
metaxin 3
chr14_+_31865099 0.31 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr22_+_2254972 0.31 ENSDART00000144906
zinc finger protein 1157
chr12_-_19119176 0.30 ENSDART00000149180
aconitase 2, mitochondrial
chr18_-_37407235 0.30 ENSDART00000132315
centrosomal protein 126
chr4_-_23759192 0.30 ENSDART00000014685
ENSDART00000131690
carboxypeptidase M
chr14_+_44804326 0.29 ENSDART00000079866
ENSDART00000172974
solute carrier family 30 (zinc transporter), member 9
chr3_-_19561058 0.29 ENSDART00000079323
zgc:163079
chr17_+_10593398 0.29 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr25_+_4812685 0.29 ENSDART00000193103
myosin VC
chr22_+_2315996 0.29 ENSDART00000132489
zinc finger protein 1175
chr5_-_67757188 0.29 ENSDART00000167168
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.5 2.6 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 1.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 0.9 GO:0061355 Wnt protein secretion(GO:0061355)
0.3 1.0 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 0.7 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.6 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.8 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 0.8 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 0.9 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 0.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 0.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 0.6 GO:1904589 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.3 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 0.6 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.7 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.4 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.5 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.6 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.4 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 1.0 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.1 GO:0030104 water homeostasis(GO:0030104)
0.1 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.4 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.3 GO:0071043 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.9 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.8 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.6 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.7 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 1.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.2 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.1 0.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.4 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.0 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.7 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 0.2 GO:1903429 regulation of cell maturation(GO:1903429)
0.1 0.9 GO:0021979 hypothalamus cell differentiation(GO:0021979) limb morphogenesis(GO:0035108)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.4 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.8 GO:0031297 replication fork processing(GO:0031297)
0.0 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.4 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.2 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.5 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.0 0.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.6 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.2 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.4 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.8 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.9 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.0 GO:0003401 axis elongation(GO:0003401)
0.0 1.4 GO:0031101 fin regeneration(GO:0031101)
0.0 0.6 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.2 GO:0045161 neuronal ion channel clustering(GO:0045161) clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.8 GO:0051604 protein maturation(GO:0051604)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:1990923 PET complex(GO:1990923)
0.2 0.6 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.4 GO:0005948 acetolactate synthase complex(GO:0005948)
0.1 0.6 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.4 GO:0000124 SAGA complex(GO:0000124)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.3 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.0 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 0.8 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.6 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 1.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0003984 acetolactate synthase activity(GO:0003984)
0.1 1.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.6 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 2.9 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 2.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.7 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID AURORA B PATHWAY Aurora B signaling
0.1 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.7 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 3.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi