ISMARA results: foxl1

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PRJNA195909:zebrafish embryo and larva development

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Results for foxl1

Z-value: 1.27

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Transcription factors associated with foxl1

Gene Symbol	Gene ID	Gene Info
foxl1 NCBI UniProt	ENSDARG00000008133	forkhead box L1
foxl1 NCBI UniProt	ENSDARG00000111418	forkhead box L1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
foxl1	dr11_v1_chr18_-_17485419_17485419	-0.65	5.8e-02	Click!

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_-_2336584 Show fit	3.25	ENSDART00000113692	tceb3l NCBI UniProt Show fit	transcription elongation factor B (SIII), polypeptide 3, like
chr2_+_29996650 Show fit	2.69	ENSDART00000138050 ENSDART00000141026	rbm33b NCBI UniProt Show fit	RNA binding motif protein 33b
chr7_-_71585065 Show fit	2.34	ENSDART00000128678	mettl4 NCBI UniProt Show fit	methyltransferase like 4
chr24_-_19719240 Show fit	2.28	ENSDART00000135405	csrnp1b NCBI UniProt Show fit	cysteine-serine-rich nuclear protein 1b
chr5_-_37117778 Show fit	1.97	ENSDART00000149138	il13ra2 NCBI UniProt Show fit	interleukin 13 receptor, alpha 2
chr7_+_58751504 Show fit	1.80	ENSDART00000024185	zgc:56231 NCBI UniProt Show fit	zgc:56231
chr18_-_6856380 Show fit	1.67	ENSDART00000175747	ppp6r2b NCBI UniProt Show fit	protein phosphatase 6, regulatory subunit 2b
chr19_-_6840506 Show fit	1.65	ENSDART00000081568	tcf19l NCBI UniProt Show fit	transcription factor 19 (SC1), like
chr3_-_8542577 Show fit	1.63	ENSDART00000183527	rbfox3b NCBI UniProt Show fit	RNA binding fox-1 homolog 3b
chr20_-_14114078 Show fit	1.61	ENSDART00000168434 ENSDART00000104032	si:ch211-223m11.2 NCBI UniProt Show fit	si:ch211-223m11.2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.3	GO:0032259	methylation(GO:0032259)
0.1	3.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	2.9	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	2.3	GO:0030901	midbrain development(GO:0030901)
0.0	2.0	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.2	1.9	GO:0043584	nose development(GO:0043584)
0.0	1.8	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
0.0	1.7	GO:0006338	chromatin remodeling(GO:0006338)
0.0	1.5	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	1.4	GO:0006284	base-excision repair(GO:0006284)

Showing 1 to 10 of 147 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.6	GO:0005871	kinesin complex(GO:0005871)
0.0	2.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	1.9	GO:0016592	mediator complex(GO:0016592)
0.0	1.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	1.6	GO:0030141	secretory granule(GO:0030141)
0.0	1.3	GO:0016605	PML body(GO:0016605)
0.0	1.3	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2	1.2	GO:0033061	DNA recombinase mediator complex(GO:0033061)
0.4	1.1	GO:0033391	chromatoid body(GO:0033391)
0.0	1.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)

Showing 1 to 10 of 62 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	3.3	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	2.5	GO:0019955	cytokine binding(GO:0019955)
0.2	2.3	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	2.0	GO:0019905	syntaxin binding(GO:0019905)
0.2	1.7	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	1.6	GO:0042803	protein homodimerization activity(GO:0042803)
0.1	1.5	GO:0015386	monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3	1.4	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0	1.4	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)

Showing 1 to 10 of 110 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	1.5	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.2	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	1.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL

Showing 1 to 10 of 28 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	1.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.0	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks

Showing 1 to 10 of 40 entries

Results for foxl1

Z-value: 1.27

Motif logo

Transcription factors associated with foxl1

Activity-expression correlation:

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: