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PRJNA195909:zebrafish embryo and larva development

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Results for foxl1

Z-value: 1.27

Motif logo

Transcription factors associated with foxl1

Gene Symbol Gene ID Gene Info
ENSDARG00000008133 forkhead box L1
ENSDARG00000111418 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxl1dr11_v1_chr18_-_17485419_17485419-0.655.8e-02Click!

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_2336584 3.25 ENSDART00000113692
transcription elongation factor B (SIII), polypeptide 3, like
chr2_+_29996650 2.69 ENSDART00000138050
ENSDART00000141026
RNA binding motif protein 33b
chr7_-_71585065 2.34 ENSDART00000128678
methyltransferase like 4
chr24_-_19719240 2.28 ENSDART00000135405
cysteine-serine-rich nuclear protein 1b
chr5_-_37117778 1.97 ENSDART00000149138
interleukin 13 receptor, alpha 2
chr7_+_58751504 1.80 ENSDART00000024185
zgc:56231
chr18_-_6856380 1.67 ENSDART00000175747
protein phosphatase 6, regulatory subunit 2b
chr19_-_6840506 1.65 ENSDART00000081568
transcription factor 19 (SC1), like
chr3_-_8542577 1.63 ENSDART00000183527
RNA binding fox-1 homolog 3b
chr20_-_14114078 1.61 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr15_-_37104165 1.59 ENSDART00000165867
zmp:0000001114
chr24_-_26632171 1.50 ENSDART00000008374
ENSDART00000017384
TRAF2 and NCK interacting kinase b
chr14_+_31618982 1.48 ENSDART00000026195
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr20_+_22799857 1.41 ENSDART00000058527
sec1 family domain containing 2
chr9_-_37367477 1.38 ENSDART00000182711
ENSDART00000192655
hspb associated protein 1
chr13_-_24260609 1.37 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr8_-_22514918 1.36 ENSDART00000021514
ENSDART00000189272
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr5_+_9224051 1.33 ENSDART00000139265
si:ch211-12e13.12
chr8_+_37749263 1.30 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr6_-_50685862 1.26 ENSDART00000134146
metastasis suppressor 1
chr14_-_45967712 1.26 ENSDART00000043751
ENSDART00000141357
MACRO domain containing 1
chr12_+_20412564 1.24 ENSDART00000186783
Rho GTPase activating protein 17a
chr2_+_1989941 1.22 ENSDART00000190814
synovial sarcoma, X breakpoint 2 interacting protein a
chr15_+_34946779 1.20 ENSDART00000192661
ENSDART00000188800
ENSDART00000156515
si:ch73-95l15.5
zgc:55621
chr23_+_14673922 1.18 ENSDART00000185086
si:rp71-79p20.2
chr15_-_30450898 1.16 ENSDART00000156584
musashi RNA-binding protein 2b
chr24_-_21090447 1.15 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr7_-_12789251 1.15 ENSDART00000052750
ADAMTS-like 3
chr23_+_7710447 1.14 ENSDART00000168199
kinesin family member 3B
chr15_-_17099560 1.14 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr9_+_42157578 1.14 ENSDART00000142888
leucine rich repeat containing 3
chr22_+_4488454 1.13 ENSDART00000170620
cortexin 1
chr16_+_44906324 1.11 ENSDART00000074960
cd22 molecule
chr20_+_35438300 1.10 ENSDART00000102504
ENSDART00000153249
tudor domain containing 6
chr16_-_27566552 1.09 ENSDART00000142102
zgc:153215
chr20_+_22799641 1.08 ENSDART00000131132
sec1 family domain containing 2
chr21_+_3244146 1.08 ENSDART00000127740
CBP80/20-dependent translation initiation factor
chr10_+_39199547 1.07 ENSDART00000075943
etoposide induced 2.4
chr12_-_1034383 1.07 ENSDART00000152455
ENSDART00000152346
polymerase (RNA) III (DNA directed) polypeptide E
chr20_+_14114258 1.06 ENSDART00000044937
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr13_+_49727333 1.05 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr15_+_28175638 1.05 ENSDART00000037119
solute carrier family 46 (folate transporter), member 1
chr7_-_6425549 1.05 ENSDART00000173323
zgc:165555
chr10_-_21362320 1.05 ENSDART00000189789
avidin
chr12_-_48188928 1.03 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr19_+_40069524 1.02 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr22_-_21845685 1.01 ENSDART00000105564
amino-terminal enhancer of split
chr15_-_20125331 1.01 ENSDART00000152355
mediator complex subunit 13b
chr16_+_7380463 1.00 ENSDART00000029727
ENSDART00000149086
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr6_+_4387150 0.99 ENSDART00000181283
RNA binding motif protein 26
chr25_+_1335530 0.97 ENSDART00000090803
fem-1 homolog b (C. elegans)
chr2_+_21312972 0.97 ENSDART00000080495
zinc finger and BTB domain containing 47a
chr7_-_16195144 0.96 ENSDART00000173492
bloodthirsty-related gene family, member 4
chr17_-_36860265 0.96 ENSDART00000182786
ENSDART00000193967
SUMO1/sentrin specific peptidase 6b
chr15_-_6615555 0.96 ENSDART00000152725
ATM serine/threonine kinase
chr8_-_21142550 0.96 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
carnitine palmitoyltransferase 2
chr20_-_34711528 0.96 ENSDART00000061555
si:ch211-63o20.7
chr10_+_32050906 0.95 ENSDART00000137373
si:ch211-266i6.3
chr15_+_34934568 0.95 ENSDART00000165210
zgc:66024
chr1_-_58900851 0.95 ENSDART00000183085
ENSDART00000188855
ENSDART00000182567
Danio rerio microfibril-associated glycoprotein 4-like (LOC100334800), transcript variant 2, mRNA.
chr5_-_30080332 0.94 ENSDART00000140049
beta-carotene oxygenase 2a
chr15_-_27522806 0.93 ENSDART00000149374
ENSDART00000187341
ENSDART00000183043
ENSDART00000189541
ENSDART00000190362
ENSDART00000193745
ENSDART00000187390
BRCA1 interacting protein C-terminal helicase 1
chr16_-_15988320 0.93 ENSDART00000160883

chr25_-_10630496 0.92 ENSDART00000153639
ENSDART00000181722
ENSDART00000177834
protein phosphatase 6, regulatory subunit 3
chr6_-_16717878 0.91 ENSDART00000153552
nodal modulator
chr4_-_75057322 0.91 ENSDART00000157935
LARGE xylosyl- and glucuronyltransferase 1
chr12_+_4225199 0.90 ENSDART00000042277
mitogen-activated protein kinase 7
chr16_-_7827365 0.88 ENSDART00000188101
T cell activation inhibitor, mitochondrial
chr3_+_7771420 0.88 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr5_+_65086856 0.88 ENSDART00000169209
ENSDART00000162409
peptidyl-tRNA hydrolase 1 homolog
chr23_+_1702624 0.87 ENSDART00000149357
Rab geranylgeranyltransferase, alpha subunit
chr2_+_56657804 0.87 ENSDART00000113964
RNA polymerase II subunit E
chr25_-_17587785 0.86 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr2_+_37245382 0.86 ENSDART00000004626
SEC62 homolog, preprotein translocation factor
chr19_+_390298 0.85 ENSDART00000136361
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_+_65086668 0.84 ENSDART00000183746
peptidyl-tRNA hydrolase 1 homolog
chr19_+_41520892 0.84 ENSDART00000182218
ENSDART00000115123
CREB regulated transcription coactivator 2
chr11_+_45286911 0.83 ENSDART00000181763
pyrroline-5-carboxylate reductase 1b
chr8_-_26709959 0.82 ENSDART00000135215
transmembrane protein 51a
chr4_+_6736746 0.82 ENSDART00000184175
transmembrane protein 168a
chr25_+_20272145 0.82 ENSDART00000109605
si:dkey-219c3.2
chr13_+_29925397 0.80 ENSDART00000123482
CUE domain containing 2
chr10_+_23060391 0.77 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr12_-_4028079 0.77 ENSDART00000128676
si:ch211-180a12.2
chr5_+_37379825 0.76 ENSDART00000171826
kelch-like family member 13
chr11_-_44979281 0.75 ENSDART00000190972
LIM-domain binding 1b
chr18_+_22287084 0.75 ENSDART00000151919
ENSDART00000181644
CCCTC-binding factor (zinc finger protein)
chr24_-_23784701 0.75 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr8_+_24299321 0.75 ENSDART00000112046
ENSDART00000183558
ENSDART00000183796
ENSDART00000181395
ENSDART00000184555
ENSDART00000172531
ENSDART00000191663
ENSDART00000184103
ENSDART00000183676
si:ch211-269m15.3
chr25_+_2776511 0.74 ENSDART00000115280
neogenin 1b
chr21_-_2814709 0.74 ENSDART00000097664
semaphorin 4D
chr23_+_7710721 0.73 ENSDART00000186852
ENSDART00000161193
kinesin family member 3B
chr15_+_31735931 0.73 ENSDART00000185681
ENSDART00000149137
relaxin/insulin-like family peptide receptor 2b
chr18_+_18405992 0.72 ENSDART00000080174
nedd4 binding protein 1
chr5_+_31995683 0.72 ENSDART00000139744
suppressor of cancer cell invasion
chr2_+_34967022 0.72 ENSDART00000134926
astrotactin 1
chr20_+_9474841 0.72 ENSDART00000053847
RAD51 paralog B
chr8_-_30395888 0.71 ENSDART00000144637
dedicator of cytokinesis 8
chr17_-_20218167 0.71 ENSDART00000154479
O-6-methylguanine-DNA methyltransferase
chr24_+_15020402 0.71 ENSDART00000148102
docking protein 6
chr9_+_29520696 0.71 ENSDART00000144430
ferredoxin 1
chr3_-_46410387 0.71 ENSDART00000156822
cell death-inducing p53 target 1
chr21_+_3093419 0.71 ENSDART00000162520
SHC adaptor protein 3
chr22_+_38276024 0.71 ENSDART00000143792
REST corepressor 3
chr15_+_25452092 0.70 ENSDART00000009545
p21 protein (Cdc42/Rac)-activated kinase 4
chr6_+_33931740 0.70 ENSDART00000130492
ENSDART00000151213
origin recognition complex, subunit 1
chr21_-_36453417 0.70 ENSDART00000018350
CCR4-NOT transcription complex, subunit 8
chr25_-_6261693 0.69 ENSDART00000135808
iron-responsive element binding protein 2
chr16_+_30002605 0.68 ENSDART00000160555
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr18_-_44359726 0.68 ENSDART00000166935
PR domain containing 10
chr6_+_28018390 0.68 ENSDART00000123324
ENSDART00000150915
Sin3A-associated protein a
chr15_-_16384184 0.68 ENSDART00000154504
family with sequence similarity 222, member Bb
chr5_+_22579975 0.68 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr24_+_402493 0.67 ENSDART00000036472
zgc:110852
chr11_+_6881001 0.67 ENSDART00000170331
kelch-like family member 26
chr25_-_13789955 0.67 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
cytoskeleton associated protein 5
chr2_+_45300512 0.67 ENSDART00000144704
calmodulin regulated spectrin-associated protein family, member 2b
chr9_+_55455801 0.66 ENSDART00000144757
ENSDART00000186543
matrix-remodelling associated 5b
chr23_+_4226341 0.66 ENSDART00000012445
zgc:113278
chr21_-_30168947 0.66 ENSDART00000130820
ENSDART00000193171
heparin-binding EGF-like growth factor b
chr20_+_23501535 0.66 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr2_-_193707 0.66 ENSDART00000187642
zinc finger protein 1014
chr21_-_42831033 0.64 ENSDART00000160998
serine/threonine kinase 10
chr7_+_36467315 0.64 ENSDART00000138893
akt interacting protein
chr21_+_3796196 0.63 ENSDART00000146754
SPOUT domain containing methyltransferase 1
chr12_-_16435150 0.63 ENSDART00000086211
polycomb group ring finger 5b
chr18_+_20468157 0.63 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
damage-specific DNA binding protein 2
chr8_+_10001805 0.63 ENSDART00000132894
si:dkey-8e10.2
chr5_+_29652198 0.63 ENSDART00000184083
TSC complex subunit 1a
chr1_+_496268 0.62 ENSDART00000109415
basic leucine zipper nuclear factor 1
chr15_+_17100412 0.62 ENSDART00000154418
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_-_41519234 0.62 ENSDART00000167283
ENSDART00000180666
golgin A1
chr11_-_18283886 0.62 ENSDART00000019248
STIM activating enhance
chr8_-_7603700 0.62 ENSDART00000137975
interleukin-1 receptor-associated kinase 1
chr15_-_25094026 0.61 ENSDART00000129154
exonuclease 5
chr25_+_15287036 0.61 ENSDART00000147572
homeodomain interacting protein kinase 3a
chr4_-_75172216 0.61 ENSDART00000127522
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr5_-_11809710 0.61 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr11_+_30282141 0.61 ENSDART00000122756
si:dkey-163f14.6
chr6_+_19948043 0.61 ENSDART00000182636
phosphoinositide-3-kinase, regulatory subunit 5
chr11_-_45152702 0.60 ENSDART00000168066
arylformamidase
chr7_+_9326234 0.60 ENSDART00000104536
chondroitin sulfate synthase 1
chr16_-_7828838 0.60 ENSDART00000191434
ENSDART00000108653
T cell activation inhibitor, mitochondrial
chr13_-_24263682 0.60 ENSDART00000176800
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr17_-_20202725 0.59 ENSDART00000133650
ecdysoneless homolog (Drosophila)
chr22_+_12595144 0.59 ENSDART00000140054
ENSDART00000060979
ENSDART00000139826
zgc:92335
chr24_-_11446156 0.59 ENSDART00000143921
ENSDART00000066778
acyl-CoA dehydrogenase family, member 11
chr18_+_6641542 0.59 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr4_-_72638972 0.59 ENSDART00000193312

chr8_+_52530889 0.58 ENSDART00000127729
ENSDART00000170360
ENSDART00000162687
STAM binding protein b
chr20_-_18536474 0.58 ENSDART00000190903
CDC42 binding protein kinase beta (DMPK-like)
chr8_+_32389838 0.58 ENSDART00000076350
ENSDART00000146901
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
chr7_+_10562118 0.58 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr1_+_13930625 0.57 ENSDART00000111026
nocturnin b
chr11_+_12811906 0.57 ENSDART00000123445
regulator of telomere elongation helicase 1
chr11_+_1867613 0.57 ENSDART00000065470
RNA binding motif, single stranded interacting protein 2a
chr2_-_23391266 0.57 ENSDART00000159048
influenza virus NS1A binding protein b
chr18_-_6855991 0.56 ENSDART00000135206
protein phosphatase 6, regulatory subunit 2b
chr13_-_44836727 0.56 ENSDART00000144385
si:dkeyp-2e4.3
chr2_-_27619954 0.56 ENSDART00000144826
trimethylguanosine synthase 1
chr15_-_7598542 0.56 ENSDART00000173092
glucan (1,4-alpha-), branching enzyme 1b
chr25_-_24248000 0.56 ENSDART00000073527
SPT2 chromatin protein domain containing 1
chr15_+_34933552 0.56 ENSDART00000155368
zgc:66024
chr15_-_1733235 0.56 ENSDART00000023153
ENSDART00000154668
RAB guanine nucleotide exchange factor (GEF) 1, like
chr15_-_17406056 0.56 ENSDART00000146735
tubulin, delta 1
chr6_+_45494227 0.56 ENSDART00000159863
contactin 4
chr10_+_44940693 0.56 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr4_+_15605844 0.56 ENSDART00000101619
ENSDART00000021384
exocyst complex component 4
chr7_+_69528850 0.56 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr20_-_3166168 0.55 ENSDART00000134137
si:ch73-212j7.3
chr15_-_41234139 0.55 ENSDART00000191628
ENSDART00000186215
solute carrier family 36 (proton/amino acid symporter), member 4
chr22_+_737211 0.55 ENSDART00000017305
zinc finger protein 76
chr24_-_29729799 0.54 ENSDART00000181250
si:ch73-383g2.1
chr11_+_22374419 0.54 ENSDART00000174683
ENSDART00000170521
ENSDART00000193980
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr2_-_43123949 0.54 ENSDART00000075347
ENSDART00000132346
leucine rich repeat containing 6
chr9_-_17783574 0.54 ENSDART00000146706
von Willebrand factor A domain containing 8
chr21_+_21791343 0.54 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr8_-_24970790 0.53 ENSDART00000141267
si:ch211-199o1.2
chr4_+_5868034 0.53 ENSDART00000166591
UTP20 small subunit (SSU) processome component
chr7_-_48173440 0.53 ENSDART00000124075
metastasis suppressor 1-like b
chr3_-_61375496 0.53 ENSDART00000165188
si:dkey-111k8.2
chr20_+_38543542 0.53 ENSDART00000145254
general transcription factor IIIC, polypeptide 2, beta
chr10_-_13396720 0.53 ENSDART00000030976
interleukin 11 receptor, alpha
chr12_-_26537145 0.53 ENSDART00000138437
ENSDART00000163931
ENSDART00000132737
acyl-CoA synthetase family member 2
chr10_+_16225553 0.52 ENSDART00000129844
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr13_-_24745288 0.52 ENSDART00000031564
SWI5-dependent homologous recombination repair protein 1
chr17_+_20504196 0.52 ENSDART00000190539
neuralized E3 ubiquitin protein ligase 1Ab
chr9_-_13963078 0.52 ENSDART00000193398
ENSDART00000061156
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr15_-_31265375 0.51 ENSDART00000086592
vascular endothelial zinc finger 1b
chr7_-_19966406 0.51 ENSDART00000010932
sorting nexin 15
chr1_+_46404968 0.51 ENSDART00000042064
tubulin, gamma complex associated protein 3
chr7_+_52949847 0.50 ENSDART00000174216
ENSDART00000174055
ENSDART00000052030
ENSDART00000174240
CDKN2A interacting protein
chr1_-_24918686 0.50 ENSDART00000148076
F-box and WD repeat domain containing 7
chr3_-_39190317 0.50 ENSDART00000013167
retinol saturase (all-trans-retinol 13,14-reductase)
chr13_+_46944607 0.50 ENSDART00000187352
F-box protein 5
chr8_-_19467011 0.50 ENSDART00000162010
zgc:92140
chr1_-_54718863 0.49 ENSDART00000122601
phosphoglycerate mutase 1b
chr12_+_33894396 0.49 ENSDART00000130853
ENSDART00000152988
major facilitator superfamily domain containing 13A
chr19_+_170705 0.47 ENSDART00000053622
ring finger protein 139
chr22_+_33135253 0.47 ENSDART00000004504
dystroglycan 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.3 1.0 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3 1.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.0 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.2 1.9 GO:0043584 nose development(GO:0043584)
0.2 0.8 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.2 0.6 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 0.9 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 0.6 GO:0015808 L-alanine transport(GO:0015808)
0.2 0.9 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.2 0.5 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.2 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.0 GO:0016572 histone phosphorylation(GO:0016572)
0.2 0.5 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.7 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 1.3 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:0070417 cellular response to cold(GO:0070417)
0.1 3.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.5 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.9 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0045830 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.6 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.9 GO:0033292 T-tubule organization(GO:0033292)
0.1 0.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.7 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.9 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.7 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 1.1 GO:0030719 P granule organization(GO:0030719)
0.1 1.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.5 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.8 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.7 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.6 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.9 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 1.2 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.4 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.4 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.4 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.1 0.4 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.7 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.3 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.1 GO:0051645 Golgi localization(GO:0051645)
0.1 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.6 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.6 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.7 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.3 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 2.3 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0060847 endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.4 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.4 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.7 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0009750 response to fructose(GO:0009750)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0009411 response to UV(GO:0009411)
0.0 0.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.6 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 1.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.4 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.4 GO:0035476 cell migration involved in sprouting angiogenesis(GO:0002042) angioblast cell migration(GO:0035476)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.8 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 0.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 4.3 GO:0032259 methylation(GO:0032259)
0.0 0.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 1.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.5 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 2.0 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 1.2 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.1 GO:0051260 protein homooligomerization(GO:0051260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0033391 chromatoid body(GO:0033391)
0.2 0.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 1.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.5 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.9 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0035060 brahma complex(GO:0035060)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0032797 SMN complex(GO:0032797)
0.0 0.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 3.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.3 1.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 1.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.7 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 0.9 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 1.1 GO:0005542 folic acid binding(GO:0005542)
0.2 1.0 GO:0009374 biotin binding(GO:0009374)
0.2 0.6 GO:0004061 arylformamidase activity(GO:0004061)
0.2 0.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 0.5 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.2 2.3 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.6 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.2 0.5 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 1.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.6 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 1.5 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0035197 siRNA binding(GO:0035197)
0.1 1.1 GO:0008494 translation activator activity(GO:0008494)
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.4 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 1.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.0 GO:0035198 miRNA binding(GO:0035198)
0.1 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.7 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.3 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 0.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.6 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.3 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.5 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 3.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 3.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.5 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.0 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.9 REACTOME KINESINS Genes involved in Kinesins
0.1 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.7 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 1.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.7 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation