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PRJNA195909:zebrafish embryo and larva development

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Results for foxk1_foxj3

Z-value: 0.86

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Transcription factors associated with foxk1_foxj3

Gene Symbol Gene ID Gene Info
ENSDARG00000037872 forkhead box K1
ENSDARG00000075774 forkhead box J3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxk1dr11_v1_chr3_-_40933415_409334150.901.0e-03Click!
foxj3dr11_v1_chr11_-_26362294_263623340.751.9e-02Click!

Activity profile of foxk1_foxj3 motif

Sorted Z-values of foxk1_foxj3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_15155684 2.21 ENSDART00000167966
zgc:158852
chr15_+_19990068 2.00 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr7_+_46019780 1.84 ENSDART00000163991
cyclin E1
chr17_+_44030692 1.44 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr13_-_33207367 1.41 ENSDART00000146138
ENSDART00000109667
ENSDART00000182741
thyroid hormone receptor interactor 11
chr16_-_47381519 1.36 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr10_-_14929392 1.27 ENSDART00000137430
SMAD family member 2
chr23_-_1571682 1.17 ENSDART00000013635
F-box protein 30b
chr17_+_14965570 1.11 ENSDART00000066604
G protein-coupled receptor 137c
chr11_+_11120532 1.11 ENSDART00000026135
ENSDART00000189872
lymphocyte antigen 75
chr22_+_38276024 1.10 ENSDART00000143792
REST corepressor 3
chr20_-_52928541 1.10 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr16_-_26820634 1.08 ENSDART00000111156
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_2690083 1.07 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr25_-_13871118 1.06 ENSDART00000160866
cryptochrome circadian clock 2
chr5_+_44944778 1.06 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr13_+_29925397 1.05 ENSDART00000123482
CUE domain containing 2
chr10_-_14929630 1.03 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
SMAD family member 2
chr4_-_20135406 1.01 ENSDART00000161343
centrosomal protein 83
chr12_-_28537615 1.00 ENSDART00000067762
si:ch211-94l19.4
chr5_+_22836364 0.98 ENSDART00000131885
si:ch211-26b3.2
chr11_+_2710530 0.96 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr1_+_53321878 0.96 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr5_-_66749535 0.92 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr7_-_46019756 0.91 ENSDART00000162583
zgc:162297
chr2_+_16696052 0.90 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr16_-_41714988 0.89 ENSDART00000138798
centrosomal protein 85
chr3_-_25369557 0.88 ENSDART00000055491
SMAD specific E3 ubiquitin protein ligase 2
chr20_+_46741074 0.85 ENSDART00000145294
si:ch211-57i17.1
chr5_+_55984270 0.85 ENSDART00000047358
ENSDART00000138191
FK506 binding protein 6
chr21_-_13661631 0.85 ENSDART00000184408
patatin-like phospholipase domain containing 7a
chr24_-_19718077 0.85 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr11_-_25257045 0.85 ENSDART00000130477
snail family zinc finger 1a
chr9_+_41459759 0.83 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr21_-_13662237 0.83 ENSDART00000091647
ENSDART00000151547
patatin-like phospholipase domain containing 7a
chr22_-_28777557 0.83 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr20_-_9428021 0.82 ENSDART00000025330
retinol dehydrogenase 14b
chr17_+_24111392 0.81 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr15_+_34069746 0.80 ENSDART00000163513
ADP-ribosylation factor-like 4aa
chr6_-_8466717 0.80 ENSDART00000151577
ENSDART00000151800
ENSDART00000151227
si:dkey-217d24.6
chr5_-_38384289 0.79 ENSDART00000135260
misshapen-like kinase 1
chr1_-_9277986 0.78 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubinuclein 1
chr25_-_13408760 0.78 ENSDART00000154445
GINS complex subunit 3
chr4_-_20135919 0.77 ENSDART00000172230
centrosomal protein 83
chr19_-_3821678 0.76 ENSDART00000169639
si:dkey-206d17.12
chr16_-_49646625 0.74 ENSDART00000101629
EF-hand domain family, member B
chr21_-_43398122 0.74 ENSDART00000050533
cyclin I family, member 2
chr11_-_25257595 0.73 ENSDART00000123567
snail family zinc finger 1a
chr5_-_4931266 0.73 ENSDART00000067600
zinc finger and BTB domain containing 43
chr16_+_25011994 0.71 ENSDART00000157312
zinc finger protein 1035
chr3_+_53116172 0.71 ENSDART00000115117
bromodomain containing 4
chr14_-_33095917 0.70 ENSDART00000074720
discs, large homolog 3 (Drosophila)
chr9_+_24088062 0.69 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr8_+_16990120 0.68 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr6_-_40922971 0.68 ENSDART00000155363
SFI1 centrin binding protein
chr5_-_68058168 0.67 ENSDART00000177026
ring finger protein 167
chr12_-_5998898 0.67 ENSDART00000142659
ENSDART00000004896
K(lysine) acetyltransferase 7b
chr2_-_24603325 0.67 ENSDART00000113356
CREB regulated transcription coactivator 1a
chr1_+_12394205 0.66 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
chr6_-_9565526 0.65 ENSDART00000151470
mitogen-activated protein kinase kinase kinase 2
chr4_-_1720648 0.65 ENSDART00000103484
growth arrest-specific 2 like 3
chr9_-_12885201 0.63 ENSDART00000124957
ankyrin repeat and zinc finger domain containing 1
chr2_-_4787566 0.63 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr16_+_9580699 0.62 ENSDART00000165565
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr20_+_53368611 0.62 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr23_+_7692042 0.61 ENSDART00000018512
protein O-fucosyltransferase 1
chr14_+_35424539 0.61 ENSDART00000171809
ENSDART00000162185
synaptotagmin-like 4
chr8_+_37749263 0.60 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr21_-_7940043 0.60 ENSDART00000099733
ENSDART00000136671
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr2_+_27386617 0.59 ENSDART00000134976
si:ch73-382f3.1
chr16_-_12097558 0.58 ENSDART00000123142
peroxisomal biogenesis factor 5
chr11_+_11030908 0.58 ENSDART00000111091
phospholipase A2 receptor 1
chr14_-_33177935 0.55 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr16_-_12097394 0.55 ENSDART00000103944
peroxisomal biogenesis factor 5
chr10_+_573667 0.55 ENSDART00000110384
SMAD family member 4a
chr3_-_26191960 0.55 ENSDART00000113843
yippee-like 3
chr5_+_36611128 0.55 ENSDART00000097684
neuro-oncological ventral antigen 1
chr11_+_25430851 0.54 ENSDART00000164999
ENSDART00000126403
si:dkey-13a21.4
chr7_-_37555208 0.54 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr22_-_34979139 0.53 ENSDART00000116455
ENSDART00000133537
Rho GTPase activating protein 19
chr15_+_25681044 0.53 ENSDART00000077853
hypermethylated in cancer 1
chr16_+_26732086 0.52 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr8_-_39859688 0.52 ENSDART00000019907
unc-119 homolog 1
chr16_+_28578352 0.52 ENSDART00000149306
N-myristoyltransferase 2
chr5_-_12743196 0.51 ENSDART00000188976
ENSDART00000137705
leucine-zipper-like transcription regulator 1
chr5_-_1827575 0.51 ENSDART00000171193
mutated in colorectal cancers
chr2_+_27330461 0.51 ENSDART00000087643
testis-specific kinase 2
chr5_+_8196264 0.50 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr22_-_29689981 0.50 ENSDART00000009223
programmed cell death 4b
chr12_-_32066469 0.50 ENSDART00000140685
ENSDART00000062185
RAB40B, member RAS oncogene family
chr3_+_19685873 0.49 ENSDART00000006490
tousled-like kinase 2
chr24_-_6678640 0.49 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr22_-_28777374 0.48 ENSDART00000188206
si:dkeyp-34c12.1
chr2_-_17492486 0.48 ENSDART00000189464
lysine (K)-specific demethylase 4A, genome duplicate b
chr21_+_20386865 0.48 ENSDART00000144366
si:dkey-30k6.5
chr8_+_4803906 0.48 ENSDART00000045533
transmembrane protein 127
chr16_+_48714048 0.48 ENSDART00000148709
ENSDART00000150121
bromodomain containing 2b
chr3_+_42999277 0.47 ENSDART00000163595
integrator complex subunit 1
chr5_-_40190949 0.47 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr18_-_5875433 0.47 ENSDART00000151727
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr15_-_28805493 0.47 ENSDART00000179617
CD3e molecule, epsilon associated protein
chr19_+_25971000 0.47 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr11_-_13341051 0.47 ENSDART00000121872
microtubule associated serine/threonine kinase 3b
chr5_+_50371509 0.46 ENSDART00000167163
SMC5-SMC6 complex localization factor 1
chr2_-_42109575 0.46 ENSDART00000075551
alcohol dehydrogenase, iron containing, 1
chr8_+_26034623 0.46 ENSDART00000004521
ENSDART00000142555
ariadne homolog 2 (Drosophila)
chr17_+_24036791 0.46 ENSDART00000140767
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr7_+_24528866 0.45 ENSDART00000180552
si:dkeyp-75h12.2
chr9_+_21306902 0.45 ENSDART00000138554
ENSDART00000004108
exportin 4
chr13_-_48431766 0.45 ENSDART00000159688
ENSDART00000171765
F-box protein 11a
chr6_-_39700965 0.45 ENSDART00000156645
extra spindle pole bodies like 1, separase
chr8_-_29822527 0.45 ENSDART00000167487
solute carrier family 20 (phosphate transporter), member 2
chr23_-_18707418 0.45 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr16_+_38350704 0.45 ENSDART00000140761
elongator acetyltransferase complex subunit 6
chr8_-_1267247 0.44 ENSDART00000150064
cell division cycle 14B
chr3_+_42999844 0.44 ENSDART00000183950
integrator complex subunit 1
chr17_+_4325693 0.44 ENSDART00000154264
minichromosome maintenance 8 homologous recombination repair factor
chr5_+_44846434 0.44 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr13_+_29926094 0.44 ENSDART00000057528
CUE domain containing 2
chr15_-_37589600 0.44 ENSDART00000154641
proline and serine rich 3
chr1_-_12394048 0.43 ENSDART00000146067
ENSDART00000134708
sodium channel and clathrin linker 1
chr18_+_15271993 0.43 ENSDART00000099777
si:dkey-103i16.6
chr20_+_25904199 0.43 ENSDART00000016864
solute carrier family 35, member F6
chr3_+_55031685 0.43 ENSDART00000132587
N-methylpurine DNA glycosylase
chr13_+_12761707 0.42 ENSDART00000015127
zgc:100846
chr6_+_4255319 0.41 ENSDART00000170351
neurobeachin-like 1
chr16_+_40954481 0.41 ENSDART00000058587
glycogen synthase kinase binding protein
chr11_+_18612421 0.41 ENSDART00000110621
nuclear receptor coactivator 3
chr12_-_22509069 0.40 ENSDART00000179755
ENSDART00000109707
neuralized E3 ubiquitin protein ligase 4
chr21_+_17051478 0.40 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr11_-_13341483 0.40 ENSDART00000164978
microtubule associated serine/threonine kinase 3b
chr12_+_30726425 0.40 ENSDART00000153275
solute carrier family 35, member F3a
chr2_+_1988036 0.39 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr1_-_23308225 0.39 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr3_-_60711127 0.38 ENSDART00000184119
UBA-like domain containing 2
chr22_-_29689485 0.38 ENSDART00000182173
programmed cell death 4b
chr20_+_42565049 0.38 ENSDART00000061101
insulin-like growth factor 2 receptor
chr18_-_13121983 0.37 ENSDART00000092648
ribitol xylosyltransferase 1
chr7_+_40205394 0.37 ENSDART00000173742
ENSDART00000148390
non-SMC condensin II complex, subunit G2
chr7_-_13906409 0.37 ENSDART00000062257
solute carrier family 39 (zinc transporter), member 1
chr5_-_51998708 0.36 ENSDART00000097194
serine incorporator 5
chr16_-_30847192 0.36 ENSDART00000191106
ENSDART00000128158
protein tyrosine kinase 2ab
chr13_-_25842074 0.36 ENSDART00000015154
poly(A) polymerase gamma
chr1_+_51191049 0.36 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr15_+_39977461 0.36 ENSDART00000063786
calcium binding protein 39
chr11_+_6295370 0.35 ENSDART00000139882
RAN binding protein 3a
chr15_+_26933196 0.35 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr5_-_24008997 0.35 ENSDART00000066645
eukaryotic translation initiation factor 1A, X-linked, a
chr13_-_5257303 0.35 ENSDART00000110610
si:dkey-78p8.1
chr19_-_22843480 0.35 ENSDART00000052503
NudC domain containing 1
chr24_+_7322116 0.35 ENSDART00000005804
X-ray repair cross complementing 2
chr14_-_34633960 0.34 ENSDART00000128869
ENSDART00000179977
actin filament associated protein 1-like 1a
chr12_+_8822717 0.34 ENSDART00000021628
receptor accessory protein 3b
chr22_+_26798853 0.34 ENSDART00000087576
ENSDART00000179780
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr23_+_31596194 0.34 ENSDART00000160748
TBP-like 1
chr23_+_31596441 0.34 ENSDART00000053534
TBP-like 1
chr10_-_38243579 0.33 ENSDART00000150159
ubiquitin specific peptidase 25
chr9_+_2343096 0.33 ENSDART00000062292
ENSDART00000191722
ENSDART00000135180
activating transcription factor 2
chr25_+_2263857 0.33 ENSDART00000076439
tyrosyl-tRNA synthetase 2, mitochondrial
chr2_-_26720854 0.33 ENSDART00000148110
si:dkey-181m9.8
chr7_+_19851422 0.33 ENSDART00000142970
ENSDART00000190027
MUS81 structure-specific endonuclease subunit
chr17_-_7218481 0.32 ENSDART00000181967
sterile alpha motif domain containing 5
chr1_-_23370395 0.32 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr15_-_7337148 0.31 ENSDART00000182568
high affinity cationic amino acid transporter 1
chr18_+_5875268 0.31 ENSDART00000177784
ENSDART00000122009
WD repeat domain 59
chr13_-_23665580 0.31 ENSDART00000144282
mitogen-activated protein kinase kinase kinase 21
chr9_-_30494727 0.31 ENSDART00000148729
si:dkey-229b18.3
chr10_-_36633882 0.31 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr23_+_32029304 0.31 ENSDART00000185217
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr23_-_45398622 0.31 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr18_+_20047374 0.31 ENSDART00000146957
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr24_+_19542323 0.31 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr10_+_2529037 0.30 ENSDART00000123467
zmp:0000001301
chr12_+_45238292 0.30 ENSDART00000057983
mitochondrial ribosomal protein L38
chr18_-_6855991 0.30 ENSDART00000135206
protein phosphatase 6, regulatory subunit 2b
chr17_+_37215820 0.30 ENSDART00000104009
solute carrier family 30 (zinc transporter), member 1b
chr21_-_41588129 0.29 ENSDART00000164125
creb3 regulatory factor
chr21_-_27273147 0.29 ENSDART00000143239
MAP/microtubule affinity-regulating kinase 2a
chr23_+_21978584 0.29 ENSDART00000145172
eukaryotic translation initiation factor 4 gamma, 3b
chr15_-_30984557 0.29 ENSDART00000080328
neurofibromin 1a
chr25_-_25142387 0.29 ENSDART00000031814
tumor susceptibility 101a
chr7_+_5530154 0.29 ENSDART00000181610
si:dkeyp-67a8.4
chr2_-_23677422 0.29 ENSDART00000079131
chromodomain protein, Y-like
chr21_-_27272657 0.28 ENSDART00000040754
ENSDART00000175009
MAP/microtubule affinity-regulating kinase 2a
chr18_+_21113216 0.28 ENSDART00000060191
lysine methyltransferase 5B
chr9_-_27868267 0.28 ENSDART00000079502
debranching RNA lariats 1
chr17_-_14966384 0.28 ENSDART00000105064
thioredoxin domain containing 16
chr19_-_47997424 0.28 ENSDART00000081675
catenin, beta 2
chr5_-_50371205 0.27 ENSDART00000157800
si:ch73-280o22.2
chr10_+_31809226 0.27 ENSDART00000087898
forkhead box O1 b
chr23_+_32028574 0.27 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr11_-_8126223 0.27 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr1_+_35494837 0.26 ENSDART00000140724
GRB2-associated binding protein 1
chr5_-_32074534 0.26 ENSDART00000112342
ENSDART00000135855
actin related protein 2/3 complex, subunit 5-like, b
chr8_+_10339869 0.26 ENSDART00000132253
TBC1 domain family, member 22B
chr5_-_25236340 0.26 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_-_23709347 0.26 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr5_-_23485161 0.26 ENSDART00000170293
ENSDART00000134069
si:dkeyp-20g2.1
si:dkeyp-20g2.3
chr24_-_5932982 0.26 ENSDART00000138412
ENSDART00000135124
ENSDART00000007373
acyl-CoA binding domain containing 5a
chr20_+_52774730 0.26 ENSDART00000014606
phosphatase and actin regulator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxk1_foxj3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 1.1 GO:0030238 male sex determination(GO:0030238)
0.3 1.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 1.1 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.2 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 1.1 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.8 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 1.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.6 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.3 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.3 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.6 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.3 GO:0061010 gall bladder development(GO:0061010)
0.1 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.6 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.9 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0036268 swimming(GO:0036268)
0.1 0.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.6 GO:0032196 transposition(GO:0032196)
0.1 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.5 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 2.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.4 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.5 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 1.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.8 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of hormone metabolic process(GO:0032350) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.2 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.0 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 1.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 1.1 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.9 GO:0030901 midbrain development(GO:0030901)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 1.2 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.4 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.3 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.4 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.5 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.1 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.1 2.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.2 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 1.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 1.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 1.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 0.5 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 0.4 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.3 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.2 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.9 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.1 GO:0042393 histone binding(GO:0042393)
0.0 1.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing