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PRJNA195909:zebrafish embryo and larva development

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Results for foxj1a+foxj1b

Z-value: 0.77

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Transcription factors associated with foxj1a+foxj1b

Gene Symbol Gene ID Gene Info
ENSDARG00000088290 forkhead box J1b
ENSDARG00000101919 forkhead box J1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxj1adr11_v1_chr3_+_60716904_60716904-0.137.3e-01Click!
foxj1bdr11_v1_chr12_+_20149707_20149707-0.088.5e-01Click!

Activity profile of foxj1a+foxj1b motif

Sorted Z-values of foxj1a+foxj1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_54014539 0.84 ENSDART00000060466
si:dkey-241l7.6
chr10_-_35257458 0.47 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr6_-_14038804 0.46 ENSDART00000184606
ENSDART00000184609
ets variant 5b
chr9_+_41459759 0.45 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr20_-_54014373 0.45 ENSDART00000152934
si:dkey-241l7.6
chr24_+_39211288 0.43 ENSDART00000061540
im:7160594
chr17_-_4252221 0.43 ENSDART00000152020
growth differentiation factor 3
chr15_+_19990068 0.43 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr14_+_26439227 0.42 ENSDART00000054183
G protein-coupled receptor 137
chr23_+_38159715 0.42 ENSDART00000137969
zgc:112994
chr16_+_26732086 0.41 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr1_+_47178529 0.39 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
MORC family CW-type zinc finger 3b
chr4_-_20135406 0.38 ENSDART00000161343
centrosomal protein 83
chr10_-_3416258 0.38 ENSDART00000005168
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr10_+_35257651 0.37 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr10_-_14929392 0.36 ENSDART00000137430
SMAD family member 2
chr13_-_7233811 0.36 ENSDART00000162026
ninein-like
chr20_+_53368611 0.36 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr12_+_3912544 0.36 ENSDART00000013465
T-box 6
chr23_-_1571682 0.36 ENSDART00000013635
F-box protein 30b
chr2_+_38271392 0.35 ENSDART00000042100
homeobox and leucine zipper encoding a
chr19_-_10915898 0.35 ENSDART00000163179
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr4_-_12795436 0.35 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr19_+_4968947 0.35 ENSDART00000003634
ENSDART00000134808
StAR-related lipid transfer (START) domain containing 3
chr13_+_29925397 0.34 ENSDART00000123482
CUE domain containing 2
chr8_+_23034718 0.34 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr1_+_51537250 0.33 ENSDART00000152789
ETAA1, ATR kinase activator
chr5_-_38342992 0.33 ENSDART00000140337
misshapen-like kinase 1
chr14_+_15155684 0.33 ENSDART00000167966
zgc:158852
chr11_+_11120532 0.32 ENSDART00000026135
ENSDART00000189872
lymphocyte antigen 75
chr5_+_44944778 0.32 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr6_-_9695294 0.32 ENSDART00000162728
NOP58 ribonucleoprotein homolog (yeast)
chr22_+_3184500 0.32 ENSDART00000176409
ENSDART00000160604
FtsJ RNA methyltransferase homolog 3
chr2_+_16696052 0.31 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr1_+_53321878 0.31 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr8_-_39859688 0.31 ENSDART00000019907
unc-119 homolog 1
chr15_-_28805493 0.30 ENSDART00000179617
CD3e molecule, epsilon associated protein
chr16_-_49646625 0.30 ENSDART00000101629
EF-hand domain family, member B
chr16_-_31435020 0.30 ENSDART00000138508
zgc:194210
chr13_+_29926094 0.30 ENSDART00000057528
CUE domain containing 2
chr6_+_32834760 0.28 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr4_-_20135919 0.28 ENSDART00000172230
centrosomal protein 83
chr16_+_9580699 0.28 ENSDART00000165565
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr22_+_7462997 0.28 ENSDART00000106082
zgc:112368
chr9_+_2041535 0.28 ENSDART00000093187
limb and neural patterns a
chr25_-_10571078 0.27 ENSDART00000153898
si:ch211-107e6.5
chr6_-_32834385 0.27 ENSDART00000129803
zinc finger CCCH-type containing 3
chr14_-_28566238 0.27 ENSDART00000172547
preproinsulin b
chr18_-_5875433 0.27 ENSDART00000151727
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr21_+_3796620 0.27 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr6_-_40922971 0.27 ENSDART00000155363
SFI1 centrin binding protein
chr21_-_30030644 0.27 ENSDART00000190810

chr15_+_34069746 0.27 ENSDART00000163513
ADP-ribosylation factor-like 4aa
chr13_-_33207367 0.26 ENSDART00000146138
ENSDART00000109667
ENSDART00000182741
thyroid hormone receptor interactor 11
chr10_-_42108137 0.26 ENSDART00000132976
ess-2 splicing factor homolog
chr22_-_28777557 0.26 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr8_+_49065348 0.26 ENSDART00000032277
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr3_-_49504023 0.26 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr5_+_29726428 0.25 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr15_-_7337148 0.25 ENSDART00000182568
high affinity cationic amino acid transporter 1
chr6_+_40922572 0.25 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr2_-_20866758 0.25 ENSDART00000165374
translocated promoter region a, nuclear basket protein
chr3_-_40664868 0.25 ENSDART00000138783
ENSDART00000178567
ring finger protein 216
chr23_+_7692042 0.25 ENSDART00000018512
protein O-fucosyltransferase 1
chr1_+_9153141 0.25 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr15_-_7337537 0.25 ENSDART00000161613
high affinity cationic amino acid transporter 1
chr2_+_20866898 0.25 ENSDART00000150086
odr-4 GPCR localization factor homolog
chr24_+_19542323 0.25 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr25_-_34740627 0.24 ENSDART00000137665
fibroblast growth factor receptor substrate 2b
chr10_-_35186310 0.24 ENSDART00000127805
POM121 transmembrane nucleoporin
chr13_+_18533005 0.24 ENSDART00000136024
finTRIM family, member 14-like
chr18_+_20226843 0.24 ENSDART00000100632
transducin-like enhancer of split 3a
chr15_+_26933196 0.24 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr7_-_38570878 0.24 ENSDART00000139187
ENSDART00000134570
ENSDART00000041055
cugbp, Elav-like family member 1
chr21_+_17051478 0.23 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr13_-_31687925 0.23 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr19_+_4856351 0.23 ENSDART00000093402
cyclin-dependent kinase 12
chr7_-_51300277 0.23 ENSDART00000174174
guanylyl cyclase 2
chr10_-_14929630 0.23 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
SMAD family member 2
chr6_-_41138854 0.23 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr4_+_5868034 0.23 ENSDART00000166591
UTP20 small subunit (SSU) processome component
chr7_+_36467315 0.22 ENSDART00000138893
akt interacting protein
chr2_-_10631767 0.22 ENSDART00000190033
metal response element binding transcription factor 2
chr21_-_30031396 0.21 ENSDART00000157167
PWWP domain containing 2A
chr17_-_20167206 0.21 ENSDART00000104874
ENSDART00000191995
prolyl 4-hydroxylase, alpha polypeptide I b
chr9_-_12885201 0.21 ENSDART00000124957
ankyrin repeat and zinc finger domain containing 1
chr17_+_14965570 0.21 ENSDART00000066604
G protein-coupled receptor 137c
chr21_-_3853204 0.21 ENSDART00000188829
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr22_+_10232527 0.21 ENSDART00000139297
si:dkeyp-87e7.4
chr16_-_26820634 0.21 ENSDART00000111156
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr23_-_45398622 0.21 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr5_+_37504309 0.21 ENSDART00000165465
si:ch1073-224n8.1
chr3_-_36419641 0.21 ENSDART00000173545
component of oligomeric golgi complex 1
chr1_-_23268013 0.20 ENSDART00000146575
replication factor C (activator 1) 1
chr4_+_11723852 0.20 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr20_-_2667902 0.20 ENSDART00000036373
cilia and flagella associated protein 206
chr2_+_41524238 0.20 ENSDART00000122860
ENSDART00000017977
activin A receptor, type 1 like
chr23_+_9508538 0.20 ENSDART00000010697
oxysterol binding protein-like 2b
chr17_-_2690083 0.20 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr15_+_39977461 0.20 ENSDART00000063786
calcium binding protein 39
chr3_+_33440615 0.20 ENSDART00000146005
GTP binding protein 1
chr19_+_25971000 0.19 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr10_-_23099809 0.19 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
notchless homolog 1 (Drosophila)
chr2_-_26720854 0.19 ENSDART00000148110
si:dkey-181m9.8
chr4_-_12795030 0.19 ENSDART00000150427
beta-2-microglobulin
chr13_+_28690355 0.19 ENSDART00000137475
ENSDART00000128246
polymerase (RNA) I polypeptide C
chr2_-_42958113 0.19 ENSDART00000139945
otoconin 90
chr2_+_1988036 0.19 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr5_-_66160415 0.19 ENSDART00000073895
membrane bound O-acyltransferase domain containing 4
chr2_+_19195841 0.19 ENSDART00000163137
ENSDART00000161095
ELOVL fatty acid elongase 1a
chr21_-_11632403 0.19 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr5_+_36895545 0.19 ENSDART00000135776
ENSDART00000147561
ENSDART00000133842
ENSDART00000051185
ENSDART00000141984
ENSDART00000136301
ENSDART00000142388
serine/arginine-rich splicing factor 7a
chr20_-_18794789 0.18 ENSDART00000003834
cerebral cavernous malformation 2
chr24_+_14240196 0.18 ENSDART00000124740
nuclear receptor coactivator 2
chr23_+_33296588 0.18 ENSDART00000030368
si:ch211-226m16.3
chr2_-_17492080 0.18 ENSDART00000024302
lysine (K)-specific demethylase 4A, genome duplicate b
chr13_-_25842074 0.18 ENSDART00000015154
poly(A) polymerase gamma
chr21_+_3796196 0.18 ENSDART00000146754
SPOUT domain containing methyltransferase 1
chr3_-_57630791 0.18 ENSDART00000129598
ubiquitin specific peptidase 36
chr16_-_41714988 0.18 ENSDART00000138798
centrosomal protein 85
chr20_-_2641233 0.18 ENSDART00000145335
ENSDART00000133121
BUB1 mitotic checkpoint serine/threonine kinase
chr2_-_23677422 0.18 ENSDART00000079131
chromodomain protein, Y-like
chr19_+_619200 0.18 ENSDART00000050125
nucleoporin like 2
chr3_-_31057624 0.18 ENSDART00000152901
armadillo repeat containing 5
chr5_-_24231139 0.17 ENSDART00000143492
SUMO1/sentrin/SMT3 specific peptidase 3a
chr14_-_33095917 0.17 ENSDART00000074720
discs, large homolog 3 (Drosophila)
chr7_+_36467796 0.17 ENSDART00000146202
akt interacting protein
chr3_-_25369557 0.17 ENSDART00000055491
SMAD specific E3 ubiquitin protein ligase 2
chr1_-_9277986 0.17 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubinuclein 1
chr14_+_30272891 0.17 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr8_-_35960987 0.17 ENSDART00000160503
solute carrier family 15 (oligopeptide transporter), member 4
chr14_-_41478265 0.17 ENSDART00000149886
ENSDART00000016002
tetraspanin 7
chr17_+_24111392 0.16 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr12_+_18899396 0.16 ENSDART00000105858
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_+_33121260 0.16 ENSDART00000058472
akirin 1
chr22_+_39007533 0.16 ENSDART00000185958
ENSDART00000129848
family with sequence similarity 208, member Aa
chr18_-_45761868 0.16 ENSDART00000025423
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr10_-_42237304 0.16 ENSDART00000140341
transcription factor 7 like 1a
chr24_-_25461267 0.16 ENSDART00000105820
membrane-bound transcription factor peptidase, site 2
chr1_+_35494837 0.16 ENSDART00000140724
GRB2-associated binding protein 1
chr12_-_22509069 0.16 ENSDART00000179755
ENSDART00000109707
neuralized E3 ubiquitin protein ligase 4
chr5_-_19014589 0.15 ENSDART00000002624
RAN binding protein 1
chr25_+_19734038 0.15 ENSDART00000067354
zgc:101783
chr22_-_28777374 0.15 ENSDART00000188206
si:dkeyp-34c12.1
chr22_+_18166660 0.15 ENSDART00000105432
BLOC-1 related complex subunit 8
chr17_+_10094063 0.15 ENSDART00000168055
Sec23 homolog A, COPII coat complex component
chr20_+_42565049 0.15 ENSDART00000061101
insulin-like growth factor 2 receptor
chr17_-_28100501 0.15 ENSDART00000149543
lysine (K)-specific demethylase 1a
chr11_+_18612421 0.15 ENSDART00000110621
nuclear receptor coactivator 3
chr16_-_21692024 0.15 ENSDART00000123597
si:ch211-154o6.2
chr5_-_66749535 0.15 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr2_+_27330461 0.15 ENSDART00000087643
testis-specific kinase 2
chr18_-_44935174 0.14 ENSDART00000081025
peroxisomal biogenesis factor 16
chr25_-_13871118 0.14 ENSDART00000160866
cryptochrome circadian clock 2
chr5_+_36895860 0.14 ENSDART00000134493
serine/arginine-rich splicing factor 7a
chr11_-_16394971 0.14 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr16_+_33121106 0.14 ENSDART00000110195
akirin 1
chr23_+_31596441 0.14 ENSDART00000053534
TBP-like 1
chr7_+_38808027 0.14 ENSDART00000052323
harbinger transposase derived 1
chr19_+_20177887 0.14 ENSDART00000008595
transformer 2 alpha homolog
chr8_-_1267247 0.14 ENSDART00000150064
cell division cycle 14B
chr2_-_31791633 0.14 ENSDART00000180662
reticulophagy regulator 1
chr25_+_3868438 0.14 ENSDART00000156438
transmembrane protein 138
chr3_+_55031685 0.14 ENSDART00000132587
N-methylpurine DNA glycosylase
chr14_-_21661015 0.14 ENSDART00000189403
ENSDART00000172442
ENSDART00000181913
lysine (K)-specific demethylase 3B
chr22_-_22231720 0.14 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr19_+_40250682 0.14 ENSDART00000102888
cyclin-dependent kinase 6
chr6_-_37745508 0.13 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr17_-_25630822 0.13 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr25_+_28555584 0.13 ENSDART00000157046
si:ch211-190o6.3
chr7_-_28611145 0.13 ENSDART00000054366
signal peptide, CUB domain, EGF-like 2
chr13_+_47821524 0.13 ENSDART00000109978
zinc finger CCCH-type containing 6
chr23_+_24598910 0.13 ENSDART00000126510
ENSDART00000078796
KAT8 regulatory NSL complex subunit 2
chr11_-_45420212 0.13 ENSDART00000182042
ENSDART00000163185
ankyrin repeat domain 13C
chr6_-_10728057 0.13 ENSDART00000002247
Sp3b transcription factor
chr7_-_50367326 0.13 ENSDART00000141926
protein regulator of cytokinesis 1b
chr5_+_40299568 0.12 ENSDART00000142157
ADP-ribosylation factor-like 15a
chr24_-_19718077 0.12 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr18_-_24988645 0.12 ENSDART00000136434
ENSDART00000085735
chromodomain helicase DNA binding protein 2
chr10_+_23099890 0.12 ENSDART00000135890
si:dkey-175g6.5
chr14_-_33425170 0.12 ENSDART00000124629
ENSDART00000105800
ENSDART00000001318
NFKB activating protein
chr12_-_28537615 0.12 ENSDART00000067762
si:ch211-94l19.4
chr3_+_32671146 0.12 ENSDART00000039466
ring finger protein 25
chr2_-_17492486 0.12 ENSDART00000189464
lysine (K)-specific demethylase 4A, genome duplicate b
chr10_+_22918338 0.12 ENSDART00000167874
ENSDART00000171298
zgc:103508
chr18_-_17399291 0.12 ENSDART00000192075
ENSDART00000060949
ENSDART00000188506
zinc finger protein, FOG family member 1
chr20_+_16173618 0.12 ENSDART00000192109
ENSDART00000104112
ENSDART00000129633
zyg-11 homolog (C. elegans)
chr11_+_16152316 0.12 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr20_-_48061351 0.12 ENSDART00000164962
prolyl endopeptidase
chr7_+_13830052 0.12 ENSDART00000191360
abhydrolase domain containing 2a
chr24_+_9298198 0.12 ENSDART00000165780
OTU deubiquitinase 1
chr19_-_22843480 0.12 ENSDART00000052503
NudC domain containing 1
chr23_-_42876596 0.12 ENSDART00000086156
discs, large (Drosophila) homolog-associated protein 4a
chr20_+_46741074 0.12 ENSDART00000145294
si:ch211-57i17.1
chr16_+_25608778 0.11 ENSDART00000077484
zinc fingers and homeoboxes 2a
chr23_-_27608257 0.11 ENSDART00000026314
PHD finger protein 8
chr24_+_17069420 0.11 ENSDART00000014787
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr8_+_4803906 0.11 ENSDART00000045533
transmembrane protein 127
chr7_-_37555208 0.11 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr6_-_18228358 0.11 ENSDART00000167937
prolyl 4-hydroxylase, beta polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of foxj1a+foxj1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:0030238 male sex determination(GO:0030238)
0.1 0.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.1 0.4 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.3 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.2 GO:0061113 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.2 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.4 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.2 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.5 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.3 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.4 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0046323 glucose import(GO:0046323)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0014009 glial cell proliferation(GO:0014009) regulation of glial cell proliferation(GO:0060251)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.1 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression