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PRJNA195909:zebrafish embryo and larva development

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Results for foxi1+foxi2+foxi3a+foxi3b

Z-value: 0.78

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Transcription factors associated with foxi1+foxi2+foxi3a+foxi3b

Gene Symbol Gene ID Gene Info
ENSDARG00000009550 forkhead box I3b
ENSDARG00000055926 forkhead box I3a
ENSDARG00000069715 forkhead box I2
ENSDARG00000104566 forkhead box i1
ENSDARG00000112022 forkhead box I3b
ENSDARG00000112303 forkhead box I3b
ENSDARG00000116791 forkhead box I2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxi3adr11_v1_chr21_+_30351256_30351256-0.853.5e-03Click!
foxi3bdr11_v1_chr14_+_34514336_34514336-0.732.6e-02Click!
foxi2dr11_v1_chr13_+_13578552_13578552-0.713.1e-02Click!
foxi1dr11_v1_chr12_-_43664682_43664682-0.304.3e-01Click!

Activity profile of foxi1+foxi2+foxi3a+foxi3b motif

Sorted Z-values of foxi1+foxi2+foxi3a+foxi3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_33647138 1.85 ENSDART00000142111
ENSDART00000015547
claudin g
chr15_+_38299385 1.46 ENSDART00000142403
si:dkey-24p1.6
chr15_+_38299563 1.38 ENSDART00000099375
si:dkey-24p1.6
chr22_+_23359369 1.32 ENSDART00000170886
DENN/MADD domain containing 1B
chr5_+_36768674 1.24 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr4_-_16628801 1.20 ENSDART00000040708
ENSDART00000064009
caprin family member 2
chr13_+_37653851 1.19 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr10_-_14929392 1.04 ENSDART00000137430
SMAD family member 2
chr19_+_29303847 0.95 ENSDART00000009149
macoilin 1a
chr7_+_13830052 0.93 ENSDART00000191360
abhydrolase domain containing 2a
chr22_-_28777557 0.92 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr3_-_2623176 0.87 ENSDART00000179792
ENSDART00000123512
si:dkey-217f16.6
chr8_+_8643901 0.78 ENSDART00000142076
ENSDART00000075624
ubiquitin specific peptidase 11
chr6_+_4255319 0.75 ENSDART00000170351
neurobeachin-like 1
chr5_-_49951106 0.75 ENSDART00000135954
family with sequence similarity 172, member A
chr1_-_6028876 0.72 ENSDART00000168117
si:ch1073-345a8.1
chr3_-_60589292 0.71 ENSDART00000157822
jumonji domain containing 6
chr18_+_27077853 0.69 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr23_-_42810664 0.68 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr4_+_11723852 0.66 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr21_+_4116437 0.66 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr19_+_1510971 0.65 ENSDART00000157721
solute carrier family 45 member 4
chr8_+_10862353 0.64 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr7_+_52766211 0.63 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr8_+_13368150 0.62 ENSDART00000114699
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr17_-_2685026 0.62 ENSDART00000191014
ENSDART00000179309
protein tyrosine phosphatase, non-receptor type 21
chr20_+_42565049 0.61 ENSDART00000061101
insulin-like growth factor 2 receptor
chr19_-_2822372 0.59 ENSDART00000109130
ENSDART00000122385
RecQ helicase-like 4
chr17_+_14965570 0.59 ENSDART00000066604
G protein-coupled receptor 137c
chr7_-_33868903 0.59 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr4_-_20135406 0.58 ENSDART00000161343
centrosomal protein 83
chr14_+_32926385 0.58 ENSDART00000139159
ligand of numb-protein X 2b
chr17_-_11417904 0.57 ENSDART00000103228
AT rich interactive domain 4A (RBP1-like)
chr7_-_49800755 0.56 ENSDART00000180072
four jointed box 1
chr16_+_38820486 0.56 ENSDART00000131866
thyrotropin-releasing hormone receptor a
chr15_+_23657051 0.55 ENSDART00000078336
kinesin light chain 3
chr2_-_31798717 0.55 ENSDART00000170880
reticulophagy regulator 1
chr2_-_51507540 0.54 ENSDART00000166605
ENSDART00000161093
polymeric immunoglobulin receptor-like 2.3
chr7_-_49801183 0.54 ENSDART00000052083
four jointed box 1
chr22_-_28777374 0.53 ENSDART00000188206
si:dkeyp-34c12.1
chr4_-_5691257 0.53 ENSDART00000110497
transmembrane protein 63A
chr3_-_55537096 0.53 ENSDART00000123544
ENSDART00000188752
testis expressed 2
chr11_+_42641404 0.52 ENSDART00000172641
ENSDART00000169938
interleukin 17 receptor D
chr17_-_11417551 0.52 ENSDART00000128291
AT rich interactive domain 4A (RBP1-like)
chr2_+_31437547 0.51 ENSDART00000141170
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr10_+_1849874 0.50 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr17_-_29271359 0.50 ENSDART00000104219
REST corepressor 1
chr14_+_15231097 0.50 ENSDART00000172430
si:dkey-203a12.3
chr9_+_27720428 0.50 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr17_+_44756247 0.50 ENSDART00000153773
CLOCK-interacting pacemaker a
chr16_+_16265850 0.49 ENSDART00000181265
SET domain containing 2
chr20_-_31252809 0.49 ENSDART00000137236
hippocalcin-like 1
chr15_-_14038227 0.47 ENSDART00000139068
zgc:114130
chr10_-_7555326 0.47 ENSDART00000162191
ENSDART00000186945
Werner syndrome
chr24_-_18659147 0.47 ENSDART00000166039
zgc:66014
chr7_+_15736230 0.46 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr4_-_20135919 0.46 ENSDART00000172230
centrosomal protein 83
chr13_+_50778187 0.45 ENSDART00000159597
deoxynucleotidyltransferase, terminal
chr17_+_25856671 0.45 ENSDART00000064817
WAPL cohesin release factor a
chr1_+_51191049 0.45 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr5_-_33215261 0.45 ENSDART00000097935
ENSDART00000134777
si:dkey-226m8.10
chr24_-_9002038 0.45 ENSDART00000066783
ENSDART00000150185
metallophosphoesterase 1
chr9_-_27719998 0.44 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
general transcription factor IIE, polypeptide 1, alpha
chr1_+_45839927 0.44 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr2_-_57110477 0.44 ENSDART00000181132
solute carrier family 25, member 42
chr11_+_16574625 0.44 ENSDART00000104072
kelch repeat and BTB (POZ) domain containing 8
chr8_-_2616326 0.43 ENSDART00000027214
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr1_+_9153141 0.43 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr18_-_21725638 0.43 ENSDART00000089853
FANCD2/FANCI-associated nuclease 1
chr10_-_11840353 0.42 ENSDART00000127581
tripartite motif containing 23
chr19_-_29303788 0.42 ENSDART00000112167
serum response factor binding protein 1
chr22_+_10543329 0.42 ENSDART00000091850
ATR interacting protein
chr3_+_53116172 0.42 ENSDART00000115117
bromodomain containing 4
chr18_+_37015185 0.41 ENSDART00000191305
signal-induced proliferation-associated 1 like 3
chr14_-_16772452 0.41 ENSDART00000137493
MRN complex interacting protein
chr10_-_7555660 0.41 ENSDART00000163689
Werner syndrome
chr15_+_25681044 0.41 ENSDART00000077853
hypermethylated in cancer 1
chr9_-_41040492 0.41 ENSDART00000163164
adenosine deaminase, tRNA-specific 3
chr3_-_33113879 0.41 ENSDART00000044677
retinoic acid receptor, alpha b
chr5_-_2676783 0.40 ENSDART00000159661

chr20_-_45062514 0.40 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr8_-_18316482 0.40 ENSDART00000190156
ring finger protein 220b
chr5_+_61361815 0.40 ENSDART00000009507
GATS protein-like 2
chr5_+_24063046 0.39 ENSDART00000051548
ENSDART00000133355
ENSDART00000142268
G protein pathway suppressor 2
chr19_+_25971000 0.39 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr25_+_6451038 0.39 ENSDART00000009971
sorting nexin 33
chr16_-_41488023 0.39 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr13_+_24679674 0.38 ENSDART00000033090
ENSDART00000139854
zgc:66426
chr2_-_10631767 0.38 ENSDART00000190033
metal response element binding transcription factor 2
chr3_+_60589157 0.38 ENSDART00000165367
methyltransferase like 23
chr9_+_2762270 0.38 ENSDART00000123342
ENSDART00000001795
ENSDART00000177563
sp3a transcription factor
chr5_+_36666715 0.38 ENSDART00000097686
zgc:153990
chr11_+_25693395 0.37 ENSDART00000110224
MON1 secretory trafficking family member Bb
chr9_+_24088062 0.37 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr9_-_12574473 0.37 ENSDART00000191372
ENSDART00000193667
insulin-like growth factor 2 mRNA binding protein 2a
chr4_+_6833735 0.37 ENSDART00000136355
dedicator of cytokinesis 4b
chr23_+_22873415 0.37 ENSDART00000135130
arginine-glutamic acid dipeptide (RE) repeats a
chr25_-_14087377 0.36 ENSDART00000124140
zgc:101566
chr17_+_37511092 0.36 ENSDART00000187935
metastasis associated 1
chr12_+_34854562 0.36 ENSDART00000130366
si:dkey-21c1.4
chr8_-_7567815 0.35 ENSDART00000132536
host cell factor C1b
chr7_+_52712807 0.35 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr16_-_41487589 0.35 ENSDART00000188115
CKLF-like MARVEL transmembrane domain containing 6
chr5_-_33255759 0.34 ENSDART00000085531
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr5_-_48070779 0.34 ENSDART00000078401
transmembrane protein 161B
chr2_+_26060528 0.34 ENSDART00000058111
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba
chr22_+_30112390 0.34 ENSDART00000191715
adducin 3 (gamma) a
chr19_-_45650994 0.34 ENSDART00000163504
trichorhinophalangeal syndrome I
chr15_+_26940569 0.34 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr7_-_37555208 0.33 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr17_+_32622933 0.33 ENSDART00000077418
cathepsin Ba
chr16_+_5612547 0.33 ENSDART00000140226
ENSDART00000189352
si:dkey-283b15.4
chr17_+_50261603 0.33 ENSDART00000154503
ENSDART00000154467
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr19_-_9503473 0.32 ENSDART00000091615
intermediate filament family orphan 1a
chr16_-_54971277 0.32 ENSDART00000113358
WD and tetratricopeptide repeats 1
chr17_+_37510834 0.32 ENSDART00000045583
metastasis associated 1
chr5_-_4931266 0.32 ENSDART00000067600
zinc finger and BTB domain containing 43
chr16_+_25608778 0.32 ENSDART00000077484
zinc fingers and homeoboxes 2a
chr23_-_33680265 0.31 ENSDART00000138416
transcription factor CP2
chr3_+_22432069 0.31 ENSDART00000123054
WNK lysine deficient protein kinase 4b
chr22_-_10752471 0.31 ENSDART00000081191
SAS-6 centriolar assembly protein
chr6_+_52918537 0.31 ENSDART00000174229
odorant receptor, family H, subfamily 137, member 1
chr6_-_40922971 0.30 ENSDART00000155363
SFI1 centrin binding protein
chr6_-_12270226 0.30 ENSDART00000180473
plakophilin 4
chr5_+_29726428 0.30 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr16_+_18535618 0.30 ENSDART00000021596
retinoid x receptor, beta b
chr8_-_8446668 0.30 ENSDART00000132700
cyclin-dependent kinase 16
chr21_-_33995710 0.30 ENSDART00000100508
ENSDART00000179622
early B cell factor 1b
chr23_-_27822920 0.29 ENSDART00000023094
activin A receptor type 1Ba
chr6_-_10037207 0.29 ENSDART00000179701
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr15_-_33807758 0.29 ENSDART00000158445
PDS5 cohesin associated factor B
chr5_-_22052852 0.29 ENSDART00000002938
myotubularin related protein 8
chr13_-_29505604 0.29 ENSDART00000110005
cadherin-related family member 1a
chr9_-_38399432 0.29 ENSDART00000148268
zinc finger protein 142
chr22_-_16154771 0.29 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr25_-_37284370 0.28 ENSDART00000103222
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr18_+_41560822 0.28 ENSDART00000158503
bromodomain adjacent to zinc finger domain, 1B
chr9_+_23770666 0.28 ENSDART00000182493
si:ch211-219a4.3
chr11_-_24523161 0.28 ENSDART00000191936
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr8_-_8446430 0.27 ENSDART00000137382
cyclin-dependent kinase 16
chr15_+_26941063 0.27 ENSDART00000149957
breast carcinoma amplified sequence 3
chr12_-_35505610 0.27 ENSDART00000105518
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr1_-_51038885 0.27 ENSDART00000035150
spastin
chr21_+_3796620 0.26 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr18_+_41561285 0.26 ENSDART00000169621
bromodomain adjacent to zinc finger domain, 1B
chr21_+_22558187 0.26 ENSDART00000167599
checkpoint kinase 1
chr23_-_22113455 0.26 ENSDART00000142474
polyhomeotic homolog 2a (Drosophila)
chr12_-_13966184 0.26 ENSDART00000066368
kelch-like family member 11
chr5_+_60919378 0.25 ENSDART00000184915
double C2-like domains, beta
chr16_-_32582798 0.25 ENSDART00000137936
F-box and leucine-rich repeat protein 4
chr4_-_12477224 0.25 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr14_-_33177935 0.25 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr18_-_44847855 0.24 ENSDART00000086823
signal recognition particle receptor (docking protein)
chr22_-_35063526 0.24 ENSDART00000162211
zgc:63733
chr20_-_29498178 0.24 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
ribonucleotide reductase M2 polypeptide
chr18_-_15532016 0.24 ENSDART00000165279
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr11_+_34523132 0.23 ENSDART00000192257
zinc finger, matrin-type 3
chr16_-_53800047 0.23 ENSDART00000158047
zinc and ring finger 2b
chr17_+_28670132 0.23 ENSDART00000076344
ENSDART00000164981
ENSDART00000182851
HECT domain containing 1
chr13_+_2442841 0.23 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
ARFGEF family member 3
chr11_+_30817943 0.22 ENSDART00000150130
ENSDART00000159997
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr4_+_6833583 0.22 ENSDART00000165179
ENSDART00000186134
ENSDART00000174507
dedicator of cytokinesis 4b
chr8_+_12930216 0.22 ENSDART00000115405
zgc:103670
chr8_-_31701157 0.22 ENSDART00000141799
F-box protein 4
chr12_-_31422433 0.21 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vesicle transport through interaction with t-SNAREs 1A
chr14_+_35024521 0.21 ENSDART00000158634
ENSDART00000170631
early B cell factor 3a
chr5_+_40299568 0.21 ENSDART00000142157
ADP-ribosylation factor-like 15a
chr22_-_14367966 0.20 ENSDART00000188796
low density lipoprotein receptor-related protein 1Ba
chr12_+_18358082 0.20 ENSDART00000123315
si:dkey-7e14.3
chr3_-_56871330 0.20 ENSDART00000014103
zgc:112148
chr15_+_21712328 0.20 ENSDART00000192553
zgc:162339
chr1_+_33647682 0.20 ENSDART00000114384
zinc finger protein 654
chr11_-_20071642 0.20 ENSDART00000162931
ENSDART00000159928
ENSDART00000191443
ENSDART00000121722
si:dkey-274m17.3
chr12_-_10476448 0.20 ENSDART00000106172
Rac family small GTPase 1a
chr17_-_14966384 0.20 ENSDART00000105064
thioredoxin domain containing 16
chr5_-_56924747 0.19 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr17_-_1705013 0.19 ENSDART00000182864

chr11_-_17713987 0.19 ENSDART00000090401
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr5_-_9931107 0.19 ENSDART00000077245
torsin family 4, member Ab
chr7_+_38808027 0.19 ENSDART00000052323
harbinger transposase derived 1
chr13_-_29505946 0.18 ENSDART00000026679
cadherin-related family member 1a
chr11_+_25681335 0.18 ENSDART00000121478
ENSDART00000190877
OTU deubiquitinase 5b
chr2_+_25198648 0.18 ENSDART00000110922
protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_18612421 0.18 ENSDART00000110621
nuclear receptor coactivator 3
chr17_-_50220228 0.18 ENSDART00000058707
Jun dimerization protein 2a
chr3_+_20012891 0.18 ENSDART00000078974
transmembrane and ubiquitin-like domain containing 2
chr7_+_29080684 0.17 ENSDART00000173709
ENSDART00000173576
ACD, shelterin complex subunit and telomerase recruitment factor
chr6_+_52873822 0.17 ENSDART00000103138
odorant receptor, family H, subfamily 137, member 3
chr6_+_52895008 0.17 ENSDART00000136143
odorant receptor, family H, subfamily 137, member 7
chr6_+_52903302 0.17 ENSDART00000143962
odorant receptor, family H, subfamily 137, member 6
chr7_+_24023653 0.16 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr6_+_46431848 0.16 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
staufen double-stranded RNA binding protein 1
chr1_+_6817292 0.16 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr2_+_47471943 0.14 ENSDART00000141974
acyl-CoA synthetase long chain family member 3b
chr2_+_47471647 0.14 ENSDART00000184199
acyl-CoA synthetase long chain family member 3b
chr22_-_21755524 0.14 ENSDART00000149635
transducin like enhancer of split 2b
chr3_-_4501026 0.14 ENSDART00000163052
zgc:162198
chr7_+_49800849 0.14 ENSDART00000164838
ENSDART00000187888
si:ch211-102l7.3
chr6_+_52911338 0.14 ENSDART00000065710
si:dkeyp-3f10.14
chr9_+_34950942 0.14 ENSDART00000077800
transcription factor Dp-1, a

Network of associatons between targets according to the STRING database.

First level regulatory network of foxi1+foxi2+foxi3a+foxi3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.4 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.9 GO:0010259 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.2 0.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 0.7 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.0 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.5 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.4 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.5 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.3 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.3 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.7 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 0.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.5 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.4 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.3 GO:0001709 cell fate determination(GO:0001709)
0.0 1.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 1.1 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 1.0 GO:0048278 vesicle docking(GO:0048278)
0.0 0.6 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 1.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 1.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 0.6 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.9 GO:0008126 acetylesterase activity(GO:0008126)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 0.4 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.4 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.6 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 1.4 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.6 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening