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PRJNA195909:zebrafish embryo and larva development

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Results for foxf1+foxf2a+foxf2b

Z-value: 0.65

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Transcription factors associated with foxf1+foxf2a+foxf2b

Gene Symbol Gene ID Gene Info
ENSDARG00000015399 forkhead box F1
ENSDARG00000017195 forkhead box F2a
ENSDARG00000070389 forkhead box F2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxf2adr11_v1_chr2_-_716426_716426-0.618.1e-02Click!
foxf1dr11_v1_chr18_+_30847237_30847237-0.551.3e-01Click!
foxf2bdr11_v1_chr20_+_26690036_26690036-0.521.5e-01Click!

Activity profile of foxf1+foxf2a+foxf2b motif

Sorted Z-values of foxf1+foxf2a+foxf2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_10394277 1.25 ENSDART00000127568
ANKH inorganic pyrophosphate transport regulator a
chr7_+_13830052 1.05 ENSDART00000191360
abhydrolase domain containing 2a
chr2_+_44512324 1.02 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
PAS domain containing serine/threonine kinase
chr17_-_4245902 0.94 ENSDART00000151851
growth differentiation factor 3
chr2_+_1988036 0.80 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr22_+_24559947 0.77 ENSDART00000169847
WD repeat domain 47b
chr24_-_10393969 0.77 ENSDART00000106260
ANKH inorganic pyrophosphate transport regulator a
chr5_-_3960161 0.76 ENSDART00000111453
myosin XIX
chr20_-_54014539 0.75 ENSDART00000060466
si:dkey-241l7.6
chr10_-_14929392 0.74 ENSDART00000137430
SMAD family member 2
chr8_-_33154677 0.73 ENSDART00000133300
zinc finger and BTB domain containing 34
chr23_-_22523303 0.72 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr12_+_13091842 0.71 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr13_+_37653851 0.68 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr1_-_6028876 0.66 ENSDART00000168117
si:ch1073-345a8.1
chr1_+_496268 0.65 ENSDART00000109415
basic leucine zipper nuclear factor 1
chr8_+_10862353 0.60 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr4_-_1720648 0.60 ENSDART00000103484
growth arrest-specific 2 like 3
chr23_+_39854566 0.58 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr17_-_27223965 0.57 ENSDART00000192577
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr6_+_2174082 0.57 ENSDART00000073936
activin A receptor type 1Bb
chr3_+_7771420 0.56 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr12_-_28537615 0.56 ENSDART00000067762
si:ch211-94l19.4
chr4_-_20135406 0.55 ENSDART00000161343
centrosomal protein 83
chr6_+_13787855 0.55 ENSDART00000182899
transmembrane protein 198b
chr9_+_55455801 0.54 ENSDART00000144757
ENSDART00000186543
matrix-remodelling associated 5b
chr8_-_6825588 0.54 ENSDART00000135834
dedicator of cytokinesis 5
chr7_-_20021450 0.54 ENSDART00000182363
thyroid hormone receptor interactor 6
chr24_+_5893134 0.54 ENSDART00000077941
microtubule associated serine/threonine kinase-like
chr12_-_5998898 0.53 ENSDART00000142659
ENSDART00000004896
K(lysine) acetyltransferase 7b
chr11_+_42422371 0.53 ENSDART00000163780
DENN/MADD domain containing 6Aa
chr2_+_44518636 0.52 ENSDART00000153733
PAS domain containing serine/threonine kinase
chr22_-_29689981 0.52 ENSDART00000009223
programmed cell death 4b
chr4_-_6373735 0.52 ENSDART00000140100
si:ch73-156e19.1
chr20_-_42378865 0.52 ENSDART00000139912
ENSDART00000015801
discoidin, CUB and LCCL domain containing 1
chr17_-_31819837 0.52 ENSDART00000160281
abraxas 2b, BRISC complex subunit
chr2_+_26060528 0.50 ENSDART00000058111
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba
chr6_+_4255319 0.50 ENSDART00000170351
neurobeachin-like 1
chr16_+_47207691 0.50 ENSDART00000062507
islet cell autoantigen 1
chr20_-_28800999 0.50 ENSDART00000049462
RAB15, member RAS oncogene family
chr7_+_25126629 0.50 ENSDART00000077217
zgc:101765
chr2_-_31686353 0.50 ENSDART00000126177
ENSDART00000056679
E2F transcription factor 5
chr1_+_53321878 0.49 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr24_+_5829265 0.49 ENSDART00000155242
si:ch211-157j23.5
chr5_+_3891485 0.49 ENSDART00000129329
ENSDART00000091711
RPA interacting protein
chr1_-_23308225 0.48 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr4_-_75157223 0.48 ENSDART00000174127

chr9_+_22780901 0.48 ENSDART00000110992
ENSDART00000143972
replication timing regulatory factor 1
chr13_-_17860307 0.48 ENSDART00000135920
ENSDART00000054579
membrane-associated ring finger (C3HC4) 8
chr10_-_11840353 0.48 ENSDART00000127581
tripartite motif containing 23
chr11_-_30508843 0.47 ENSDART00000101667
ENSDART00000179930
mitogen-activated protein kinase kinase kinase kinase 3a
chr4_+_9467049 0.47 ENSDART00000012659
zgc:55888
chr23_-_12453700 0.47 ENSDART00000091140
sorting nexin family member 21
chr5_-_30074332 0.47 ENSDART00000147963
beta-carotene oxygenase 2a
chr12_+_35316233 0.47 ENSDART00000178663
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr16_+_4178949 0.46 ENSDART00000188592
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr24_+_17069420 0.46 ENSDART00000014787
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr18_-_12858016 0.46 ENSDART00000130343
poly (ADP-ribose) polymerase family, member 12a
chr13_-_10620652 0.45 ENSDART00000135000
ENSDART00000191587
si:ch73-54n14.2
calmodulin-lysine N-methyltransferase
chr11_-_24523161 0.45 ENSDART00000191936
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr5_-_15264007 0.45 ENSDART00000180641
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr4_-_20135919 0.45 ENSDART00000172230
centrosomal protein 83
chr4_+_14981854 0.45 ENSDART00000067046
cation/H+ exchanger protein 1
chr17_+_7534180 0.44 ENSDART00000187512
SNF2 histone linker PHD RING helicase
chr23_-_1571682 0.44 ENSDART00000013635
F-box protein 30b
chr15_+_23657051 0.44 ENSDART00000078336
kinesin light chain 3
chr21_-_13856689 0.44 ENSDART00000102197
family with sequence similarity 129, member Ba
chr15_+_19990068 0.44 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr3_+_32571929 0.43 ENSDART00000151025
si:ch73-248e21.1
chr22_-_10752471 0.43 ENSDART00000081191
SAS-6 centriolar assembly protein
chr6_-_53885514 0.43 ENSDART00000173812
ENSDART00000127144
calcium channel, voltage-dependent, alpha 2/delta subunit 2a
chr2_+_27651984 0.43 ENSDART00000126762
transmembrane protein 68
chr11_-_8126223 0.43 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr2_+_27330461 0.43 ENSDART00000087643
testis-specific kinase 2
chr7_+_52712807 0.43 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr1_+_51191049 0.43 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr4_-_5691257 0.43 ENSDART00000110497
transmembrane protein 63A
chr11_+_43751263 0.43 ENSDART00000163843
zgc:153431
chr13_-_18011168 0.43 ENSDART00000144813
membrane-associated ring finger (C3HC4) 8
chr11_+_25583950 0.43 ENSDART00000111961
coiled-coil domain containing 120
chr14_-_26465729 0.43 ENSDART00000143454
synovial apoptosis inhibitor 1, synoviolin
chr23_-_18707418 0.42 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr8_-_30424182 0.42 ENSDART00000099021
dedicator of cytokinesis 8
chr23_-_25686894 0.42 ENSDART00000181420
ENSDART00000088208
low density lipoprotein receptor-related protein 1Ab
chr1_+_10129099 0.42 ENSDART00000187740
RNA binding motif protein 46
chr20_-_33487729 0.42 ENSDART00000061843
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr14_+_8638353 0.42 ENSDART00000163240
si:dkeyp-115e12.6
chr24_-_23784701 0.42 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr7_+_15736230 0.41 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr2_+_27652386 0.41 ENSDART00000188261
transmembrane protein 68
chr15_-_28908027 0.40 ENSDART00000182790
ENSDART00000192461
echinoderm microtubule associated protein like 2
chr22_-_12337781 0.40 ENSDART00000188357
ENSDART00000123574
zinc finger, RAN-binding domain containing 3
chr23_+_13533885 0.40 ENSDART00000144386
uridine-cytidine kinase 1-like 1b
chr6_-_32834385 0.39 ENSDART00000129803
zinc finger CCCH-type containing 3
chr20_+_52774730 0.39 ENSDART00000014606
phosphatase and actin regulator 1
chr7_+_52766211 0.39 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr25_+_2776865 0.39 ENSDART00000156567
neogenin 1b
chr16_-_35532937 0.39 ENSDART00000193209
CTP synthase 1b
chr20_-_48877458 0.39 ENSDART00000163271
5'-3' exoribonuclease 2
chr1_+_50639416 0.39 ENSDART00000141977
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr24_-_26632171 0.38 ENSDART00000008374
ENSDART00000017384
TRAF2 and NCK interacting kinase b
chr21_-_36453594 0.38 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr15_-_7337148 0.38 ENSDART00000182568
high affinity cationic amino acid transporter 1
chr19_+_24068223 0.38 ENSDART00000141351
ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr23_-_35483163 0.38 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr8_+_29636431 0.38 ENSDART00000133047
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr12_+_17154655 0.37 ENSDART00000028003
ankyrin repeat domain 22
chr15_+_44283723 0.37 ENSDART00000167722
CWF19-like 2, cell cycle control (S. pombe)
chr2_-_44777592 0.37 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr10_+_43117661 0.37 ENSDART00000024644
ENSDART00000186932
X-ray repair complementing defective repair in Chinese hamster cells 4
chr18_-_44935174 0.37 ENSDART00000081025
peroxisomal biogenesis factor 16
chr25_-_34740627 0.37 ENSDART00000137665
fibroblast growth factor receptor substrate 2b
chr16_-_29403711 0.37 ENSDART00000175571
toll-like receptor 18
chr1_+_21937201 0.37 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr10_+_41939963 0.37 ENSDART00000126248
transmembrane protein 120B
chr3_-_56871330 0.37 ENSDART00000014103
zgc:112148
chr24_+_17068724 0.37 ENSDART00000191137
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr7_+_13824150 0.37 ENSDART00000035067
abhydrolase domain containing 2a
chr19_+_43669122 0.36 ENSDART00000139151
si:ch211-193k19.1
chr15_+_26941063 0.36 ENSDART00000149957
breast carcinoma amplified sequence 3
chr15_+_26940569 0.36 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr2_+_8261109 0.36 ENSDART00000024677
deleted in autism 1a
chr15_-_33807758 0.36 ENSDART00000158445
PDS5 cohesin associated factor B
chr9_-_28939796 0.36 ENSDART00000101269
erythrocyte membrane protein band 4.1 like 5
chr4_-_18416566 0.36 ENSDART00000033717
CASP2 and RIPK1 domain containing adaptor with death domain
chr5_+_66250856 0.36 ENSDART00000132789
SECIS binding protein 2
chr16_-_54971277 0.36 ENSDART00000113358
WD and tetratricopeptide repeats 1
chr9_+_24088062 0.36 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr16_-_27566552 0.36 ENSDART00000142102
zgc:153215
chr20_+_42565049 0.35 ENSDART00000061101
insulin-like growth factor 2 receptor
chr9_+_42607138 0.35 ENSDART00000138133
ENSDART00000002027
GULP, engulfment adaptor PTB domain containing 1a
chr3_+_26288981 0.35 ENSDART00000163500
ras homolog family member T1a
chr7_-_37555208 0.35 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr20_-_31496679 0.35 ENSDART00000153437
ENSDART00000153193
SAM and SH3 domain containing 1a
chr15_-_36727462 0.35 ENSDART00000085971
nephrosis 1, congenital, Finnish type (nephrin)
chr15_+_25681044 0.35 ENSDART00000077853
hypermethylated in cancer 1
chr2_+_30969029 0.35 ENSDART00000085242
lipin 2
chr16_+_11297703 0.35 ENSDART00000125158
zinc finger protein 574
chr5_-_23749348 0.34 ENSDART00000140766
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
chr18_-_7677208 0.34 ENSDART00000092456
SH3 and multiple ankyrin repeat domains 3a
chr9_+_41459759 0.34 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr2_-_31798717 0.34 ENSDART00000170880
reticulophagy regulator 1
chr20_-_45062514 0.34 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr12_+_27704015 0.34 ENSDART00000153256
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr18_-_6832337 0.34 ENSDART00000139360
protein phosphatase 6, regulatory subunit 2b
chr7_-_60351537 0.34 ENSDART00000159875
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr5_+_30392148 0.34 ENSDART00000086765
serine/threonine kinase 36 (fused homolog, Drosophila)
chr7_-_60351876 0.33 ENSDART00000098563
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr3_-_29910547 0.33 ENSDART00000151501
si:dkey-151m15.5
chr20_+_23742574 0.33 ENSDART00000050559
SH3 domain containing ring finger 1
chr4_+_11723852 0.33 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr13_+_10621257 0.32 ENSDART00000008603
prolyl endopeptidase-like
chr15_+_20352123 0.32 ENSDART00000011030
ENSDART00000163532
ENSDART00000169537
ENSDART00000161047
interleukin 15, like
chr5_+_8196264 0.32 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr15_-_7598294 0.32 ENSDART00000165898
glucan (1,4-alpha-), branching enzyme 1b
chr20_-_53949798 0.32 ENSDART00000153435
protein phosphatase 2, regulatory subunit B', gamma b
chr16_-_32582798 0.32 ENSDART00000137936
F-box and leucine-rich repeat protein 4
chr12_-_35582683 0.32 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr17_-_23709347 0.32 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr12_+_2648043 0.32 ENSDART00000082220
growth differentiation factor 2
chr19_+_7549854 0.32 ENSDART00000138866
ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr3_+_24511959 0.31 ENSDART00000133898
dynein, axonemal, light chain 4a
chr23_+_44236281 0.31 ENSDART00000149842
si:ch1073-157b13.1
chr12_-_18961491 0.31 ENSDART00000172574
E1A binding protein p300 a
chr6_+_32834760 0.31 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr7_-_49651378 0.31 ENSDART00000015040
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr17_-_40956035 0.31 ENSDART00000124715
si:dkey-16j16.4
chr11_+_6881001 0.31 ENSDART00000170331
kelch-like family member 26
chr2_-_51507540 0.31 ENSDART00000166605
ENSDART00000161093
polymeric immunoglobulin receptor-like 2.3
chr5_-_22573624 0.31 ENSDART00000131889
ENSDART00000080886
ENSDART00000147513
ENSDART00000080882
apoptosis-inducing factor, mitochondrion-associated 1
chr10_+_17371356 0.31 ENSDART00000122663
signal peptide peptidase 3
chr19_-_24135824 0.31 ENSDART00000189505
ENSDART00000104087
THAP domain containing 7
chr9_-_27719998 0.31 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
general transcription factor IIE, polypeptide 1, alpha
chr25_+_4812685 0.30 ENSDART00000193103
myosin VC
chr19_-_9503473 0.30 ENSDART00000091615
intermediate filament family orphan 1a
chr12_+_18906407 0.30 ENSDART00000105854
Josephin domain containing 1
chr13_-_22961605 0.30 ENSDART00000143112
ENSDART00000057641
tetraspanin 15
chr17_+_44756247 0.30 ENSDART00000153773
CLOCK-interacting pacemaker a
chr12_+_34854562 0.30 ENSDART00000130366
si:dkey-21c1.4
chr3_+_18567560 0.30 ENSDART00000124329
chromobox homolog 8a (Pc class homolog, Drosophila)
chr14_+_22498757 0.30 ENSDART00000021657
SMYD family member 5
chr12_-_35582521 0.30 ENSDART00000162175
ENSDART00000168958
SEC24 homolog C, COPII coat complex component
chr11_-_11336986 0.30 ENSDART00000016677
zgc:77929
chr14_+_30413758 0.30 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr9_+_27720428 0.29 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr12_-_48374728 0.29 ENSDART00000153403
ENSDART00000188117
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr15_+_31911989 0.29 ENSDART00000111472
breast cancer 2, early onset
chr23_-_36670369 0.29 ENSDART00000006881
zinc finger and BTB domain containing 39
chr7_+_10563017 0.29 ENSDART00000193520
ENSDART00000173125
zinc finger, AN1-type domain 6
chr11_+_24348425 0.29 ENSDART00000089747
NFS1 cysteine desulfurase
chr21_-_30030644 0.29 ENSDART00000190810

chr6_+_21536131 0.29 ENSDART00000113911
ENSDART00000188472
MICAL-like 1a
chr20_+_20731633 0.29 ENSDART00000191952
ENSDART00000165224
protein phosphatase 1, regulatory subunit 13Bb
chr12_-_13966184 0.29 ENSDART00000066368
kelch-like family member 11
chr22_+_12361317 0.29 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr2_+_31437547 0.29 ENSDART00000141170
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr8_-_7603700 0.29 ENSDART00000137975
interleukin-1 receptor-associated kinase 1
chr19_+_43716607 0.28 ENSDART00000133199
CAP, adenylate cyclase-associated protein 1 (yeast)
chr7_+_24889783 0.28 ENSDART00000005329
ENSDART00000159955
MAP/microtubule affinity-regulating kinase 2b
chr5_-_29122834 0.28 ENSDART00000087197
whirlin b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxf1+foxf2a+foxf2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 0.9 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.3 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.3 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 2.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.6 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.4 GO:0006266 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.2 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.5 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.3 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.2 GO:0010259 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.4 GO:0048478 replication fork protection(GO:0048478)
0.1 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.2 GO:1903430 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.1 0.9 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.3 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.3 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.6 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.4 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0090279 regulation of calcium ion import(GO:0090279)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.4 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0090660 regulation of microtubule polymerization(GO:0031113) cerebrospinal fluid circulation(GO:0090660)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.4 GO:0008585 female gonad development(GO:0008585)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.1 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0051224 negative regulation of protein transport(GO:0051224) negative regulation of establishment of protein localization(GO:1904950)
0.0 0.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.2 GO:0060389 pathway-restricted SMAD protein phosphorylation(GO:0060389)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.7 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0045141 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.9 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.5 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.2 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0048796 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.2 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.0 GO:0048278 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.6 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.6 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.0 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.3 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.6 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.4 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.2 GO:0031167 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) rRNA methylation(GO:0031167)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:0097268 cytoophidium(GO:0097268)
0.1 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.9 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0000775 chromosome, centromeric region(GO:0000775)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.2 1.4 GO:0008126 acetylesterase activity(GO:0008126)
0.2 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 0.6 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.4 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.2 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.3 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.3 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0048156 tau protein binding(GO:0048156)
0.1 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.2 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.7 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.0 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004067 asparaginase activity(GO:0004067)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling