ISMARA results: foxb1b+foxb2

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PRJNA195909:zebrafish embryo and larva development

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Results for foxb1b+foxb2

Z-value: 2.44

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Transcription factors associated with foxb1b+foxb2

Gene Symbol	Gene ID	Gene Info
foxb2 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000037475	forkhead box B2
foxb1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000053650	forkhead box B1b
foxb1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000110408	forkhead box B1b
foxb1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000113373	forkhead box B1b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
foxb1b	dr11_v1_chr7_+_29461060_29461060	-0.61	8.3e-02	Click!
foxb2	dr11_v1_chr8_-_38506339_38506339	-0.32	4.0e-01	Click!

Activity profile of foxb1b+foxb2 motif

Sorted Z-values of foxb1b+foxb2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_37749263 Show fit	4.88	ENSDART00000108556 ENSDART00000147942	npm2a NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleophosmin/nucleoplasmin, 2a
chr11_-_6452444 Show fit	4.59	ENSDART00000137879 ENSDART00000134957 ENSDART00000004483	larp6b NCBI UniProt ZFIN ENSEMBL Google Show fit	La ribonucleoprotein domain family, member 6b
chr9_-_8314028 Show fit	4.58	ENSDART00000102739	si:ch211-145c1.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-145c1.1
chr5_-_33236637 Show fit	4.46	ENSDART00000085512 ENSDART00000144694	kank1b NCBI UniProt ZFIN ENSEMBL Google Show fit	KN motif and ankyrin repeat domains 1b
chr23_+_44236281 Show fit	3.72	ENSDART00000149842	MEPCE NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-157b13.1
chr14_+_15155684 Show fit	3.63	ENSDART00000167966	zgc:158852 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:158852
chr5_-_17876709 Show fit	3.43	ENSDART00000141978	si:dkey-112e17.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-112e17.1
chr16_-_47381519 Show fit	3.36	ENSDART00000032188 ENSDART00000150136	si:dkey-256h2.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-256h2.1
chr12_+_2648043 Show fit	3.19	ENSDART00000082220	gdf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	growth differentiation factor 2
chr8_-_25771474 Show fit	3.12	ENSDART00000193883	suv39h1b NCBI UniProt ZFIN ENSEMBL Google Show fit	suppressor of variegation 3-9 homolog 1b
chr7_-_37555208 Show fit	3.10	ENSDART00000148905 ENSDART00000150229	cylda NCBI UniProt ZFIN ENSEMBL Google Show fit	cylindromatosis (turban tumor syndrome), a
chr14_-_7409364 Show fit	3.03	ENSDART00000036463	dnd1 NCBI UniProt ZFIN ENSEMBL Google Show fit	DND microRNA-mediated repression inhibitor 1
chr11_+_11120532 Show fit	3.01	ENSDART00000026135 ENSDART00000189872	ly75 NCBI UniProt ZFIN ENSEMBL Google Show fit	lymphocyte antigen 75
chr13_-_33207367 Show fit	2.95	ENSDART00000146138 ENSDART00000109667 ENSDART00000182741	trip11 NCBI UniProt ZFIN ENSEMBL Google Show fit	thyroid hormone receptor interactor 11
chr5_-_68782641 Show fit	2.86	ENSDART00000141699	mepce NCBI UniProt ZFIN ENSEMBL Google Show fit	methylphosphate capping enzyme
chr17_+_24036791 Show fit	2.73	ENSDART00000140767	b3gnt2b NCBI UniProt ZFIN ENSEMBL Google Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr7_+_46019780 Show fit	2.69	ENSDART00000163991	ccne1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin E1
chr22_-_38819603 Show fit	2.68	ENSDART00000104437	si:ch211-262h13.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-262h13.5
chr1_-_8917902 Show fit	2.67	ENSDART00000137900	grin2ab NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr8_+_23726708 Show fit	2.59	ENSDART00000142395	mkrn4 NCBI UniProt ZFIN ENSEMBL Google Show fit	makorin, ring finger protein, 4
chr20_-_52928541 Show fit	2.51	ENSDART00000162812	fdft1 NCBI UniProt ZFIN ENSEMBL Google Show fit	farnesyl-diphosphate farnesyltransferase 1
chr20_+_42918755 Show fit	2.49	ENSDART00000134855	efr3bb NCBI UniProt ZFIN ENSEMBL Google Show fit	EFR3 homolog Bb (S. cerevisiae)
chr22_-_5171829 Show fit	2.49	ENSDART00000140313	tnfaip8l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor necrosis factor, alpha-induced protein 8-like 1
chr15_+_19991280 Show fit	2.38	ENSDART00000186677	zgc:112083 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:112083
chr17_+_44030692 Show fit	2.37	ENSDART00000049503	peli2 NCBI UniProt ZFIN ENSEMBL Google Show fit	pellino E3 ubiquitin protein ligase family member 2
chr25_-_13408760 Show fit	2.33	ENSDART00000154445	gins3 NCBI UniProt ZFIN ENSEMBL Google Show fit	GINS complex subunit 3
chr9_-_27391908 Show fit	2.29	ENSDART00000135221	nepro NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleolus and neural progenitor protein
chr4_-_12781182 Show fit	2.28	ENSDART00000058020	helb NCBI UniProt ZFIN ENSEMBL Google Show fit	helicase (DNA) B
chr9_-_46072805 Show fit	2.27	ENSDART00000169682	hdac4 NCBI UniProt ZFIN ENSEMBL Google Show fit	histone deacetylase 4
chr3_+_14512670 Show fit	2.26	ENSDART00000161403	rab3db NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB3D, member RAS oncogene family, b
chr12_+_38807604 Show fit	2.23	ENSDART00000155563	abca5 NCBI UniProt ZFIN ENSEMBL Google Show fit	ATP-binding cassette, sub-family A (ABC1), member 5
chr22_-_17631675 Show fit	2.22	ENSDART00000132565	hmha1b NCBI UniProt ZFIN ENSEMBL Google Show fit	histocompatibility (minor) HA-1 b
chr3_-_48603471 Show fit	2.22	ENSDART00000189027	ndel1b NCBI UniProt ZFIN ENSEMBL Google Show fit	nudE neurodevelopment protein 1-like 1b
chr1_+_21937201 Show fit	2.20	ENSDART00000087729	kdm4c NCBI UniProt ZFIN ENSEMBL Google Show fit	lysine (K)-specific demethylase 4C
chr4_-_14207471 Show fit	2.17	ENSDART00000015134	twf1b NCBI UniProt ZFIN ENSEMBL Google Show fit	twinfilin actin-binding protein 1b
chr16_-_25233515 Show fit	2.16	ENSDART00000058943	zgc:110182 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:110182
chr6_-_41138854 Show fit	2.14	ENSDART00000128723 ENSDART00000151055 ENSDART00000132484	slc6a22.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 6 member 22, tandem duplicate 1
chr25_+_15994100 Show fit	2.14	ENSDART00000144723	ppfibp2b NCBI UniProt ZFIN ENSEMBL Google Show fit	PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr15_-_8856391 Show fit	2.13	ENSDART00000008273	rab4b NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB4B, member RAS oncogene family
chr7_+_59677273 Show fit	2.11	ENSDART00000039535 ENSDART00000132044	trmt44 NCBI UniProt ZFIN ENSEMBL Google Show fit	tRNA methyltransferase 44 homolog
chr20_+_46741074 Show fit	2.11	ENSDART00000145294	si:ch211-57i17.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-57i17.1
chr22_-_5171362 Show fit	2.10	ENSDART00000124889	tnfaip8l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor necrosis factor, alpha-induced protein 8-like 1
chr10_-_6587066 Show fit	2.09	ENSDART00000171833	chd1 NCBI UniProt ZFIN ENSEMBL Google Show fit	chromodomain helicase DNA binding protein 1
chr14_+_30285613 Show fit	2.09	ENSDART00000173090	mtus1a NCBI UniProt ZFIN ENSEMBL Google Show fit	microtubule associated tumor suppressor 1a
chr17_-_1705013 Show fit	2.04	ENSDART00000182864	CABZ01086293.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr8_+_23726244 Show fit	1.99	ENSDART00000132734	mkrn4 NCBI UniProt ZFIN ENSEMBL Google Show fit	makorin, ring finger protein, 4
chr23_-_1571682 Show fit	1.97	ENSDART00000013635	fbxo30b NCBI UniProt ZFIN ENSEMBL Google Show fit	F-box protein 30b
chr2_-_4787566 Show fit	1.96	ENSDART00000160663 ENSDART00000157808	tnk2b NCBI UniProt ZFIN ENSEMBL Google Show fit	tyrosine kinase, non-receptor, 2b
chr5_-_50084310 Show fit	1.95	ENSDART00000074599 ENSDART00000189970	fam172a NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 172, member A
chr17_-_30652738 Show fit	1.95	ENSDART00000154960	sh3yl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	SH3 and SYLF domain containing 1
chr20_-_35512932 Show fit	1.95	ENSDART00000137690	adgrf3b NCBI UniProt ZFIN ENSEMBL Google Show fit	adhesion G protein-coupled receptor F3b
chr12_+_18916285 Show fit	1.94	ENSDART00000127536	cbx7b NCBI UniProt ZFIN ENSEMBL Google Show fit	chromobox homolog 7b
chr14_+_50918769 Show fit	1.94	ENSDART00000146918	rnf44 NCBI UniProt ZFIN ENSEMBL Google Show fit	ring finger protein 44
chr21_+_3928947 Show fit	1.93	ENSDART00000149777	setx NCBI UniProt ZFIN ENSEMBL Google Show fit	senataxin
chr22_+_38276024 Show fit	1.91	ENSDART00000143792	rcor3 NCBI UniProt ZFIN ENSEMBL Google Show fit	REST corepressor 3
chr6_-_8466717 Show fit	1.90	ENSDART00000151577 ENSDART00000151800 ENSDART00000151227	si:dkey-217d24.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-217d24.6
chr13_+_43050562 Show fit	1.90	ENSDART00000016602	cdh23 NCBI UniProt ZFIN ENSEMBL Google Show fit	cadherin-related 23
chr25_-_18435481 Show fit	1.90	ENSDART00000004771	poc1b NCBI UniProt ZFIN ENSEMBL Google Show fit	POC1 centriolar protein B
chr19_-_10915898 Show fit	1.89	ENSDART00000163179	pip5k1aa NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr11_-_25257045 Show fit	1.88	ENSDART00000130477	snai1a NCBI UniProt ZFIN ENSEMBL Google Show fit	snail family zinc finger 1a
chr4_-_14624481 Show fit	1.87	ENSDART00000137847	plxnb2a NCBI UniProt ZFIN ENSEMBL Google Show fit	plexin b2a
chr16_-_26820634 Show fit	1.86	ENSDART00000111156	pdp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_+_25213229 Show fit	1.86	ENSDART00000110451	arhgef10 NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho guanine nucleotide exchange factor (GEF) 10
chr11_+_2600612 Show fit	1.82	ENSDART00000173442	dnajc14 NCBI UniProt ZFIN ENSEMBL Google Show fit	DnaJ (Hsp40) homolog, subfamily C, member 14
chr2_-_57941037 Show fit	1.82	ENSDART00000131420	si:dkeyp-68b7.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-68b7.5
chr2_+_34112100 Show fit	1.81	ENSDART00000056666 ENSDART00000146624	klhl20 NCBI UniProt ZFIN ENSEMBL Google Show fit	kelch-like family member 20
chr13_-_15799391 Show fit	1.80	ENSDART00000124688	bag5 NCBI UniProt ZFIN ENSEMBL Google Show fit	BCL2 associated athanogene 5
chr21_-_22871901 Show fit	1.79	ENSDART00000065556	polq NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (DNA directed), theta
chr7_+_33372680 Show fit	1.77	ENSDART00000193436 ENSDART00000099988	glceb NCBI UniProt ZFIN ENSEMBL Google Show fit	glucuronic acid epimerase b
chr19_-_46091497 Show fit	1.77	ENSDART00000178772 ENSDART00000167255	ptdss1b NCBI UniProt ZFIN ENSEMBL Google Show fit si:dkey-108k24.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphatidylserine synthase 1b si:dkey-108k24.2
chr8_-_35960987 Show fit	1.76	ENSDART00000160503	slc15a4 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 15 (oligopeptide transporter), member 4
chr2_-_389867 Show fit	1.76	ENSDART00000004848	wrnip1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Werner helicase interacting protein 1
chr6_-_39700965 Show fit	1.76	ENSDART00000156645	espl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	extra spindle pole bodies like 1, separase
chr9_-_3519717 Show fit	1.74	ENSDART00000145043	dcaf17 NCBI UniProt ZFIN ENSEMBL Google Show fit	ddb1 and cul4 associated factor 17
chr23_+_21978816 Show fit	1.74	ENSDART00000087110	eif4g3b NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 4 gamma, 3b
chr25_-_12412704 Show fit	1.73	ENSDART00000168275	det1 NCBI UniProt ZFIN ENSEMBL Google Show fit	DET1, COP1 ubiquitin ligase partner
chr5_-_65121747 Show fit	1.72	ENSDART00000165556	tor2a NCBI UniProt ZFIN ENSEMBL Google Show fit	torsin family 2, member A
chr12_-_28537615 Show fit	1.72	ENSDART00000067762	MYO1D NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-94l19.4
chr22_+_9003090 Show fit	1.71	ENSDART00000106414	rnh1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribonuclease/angiogenin inhibitor 1
chr9_+_54237100 Show fit	1.70	ENSDART00000148928	rbm27 NCBI UniProt ZFIN ENSEMBL Google Show fit	RNA binding motif protein 27
chr23_+_21978584 Show fit	1.70	ENSDART00000145172	eif4g3b NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 4 gamma, 3b
chr20_-_34388324 Show fit	1.69	ENSDART00000133593 ENSDART00000136591	swt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	SWT1 RNA endoribonuclease homolog
chr7_-_58178807 Show fit	1.69	ENSDART00000188531	nsmaf NCBI UniProt ZFIN ENSEMBL Google Show fit	neutral sphingomyelinase (N-SMase) activation associated factor
chr9_+_2343096 Show fit	1.68	ENSDART00000062292 ENSDART00000191722 ENSDART00000135180	atf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	activating transcription factor 2
chr4_-_13613148 Show fit	1.67	ENSDART00000067164 ENSDART00000111247	irf5 NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 5
chr19_-_3821678 Show fit	1.67	ENSDART00000169639	si:dkey-206d17.12 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-206d17.12
chr16_+_40954481 Show fit	1.66	ENSDART00000058587	gbp NCBI UniProt ZFIN ENSEMBL Google Show fit	glycogen synthase kinase binding protein
chr5_-_41709234 Show fit	1.65	ENSDART00000083656	atxn2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ataxin 2
chr15_-_37589600 Show fit	1.65	ENSDART00000154641	proser3 NCBI UniProt ZFIN ENSEMBL Google Show fit	proline and serine rich 3
chr9_-_32158288 Show fit	1.65	ENSDART00000037182	ankrd44 NCBI UniProt ZFIN ENSEMBL Google Show fit	ankyrin repeat domain 44
chr4_+_6735053 Show fit	1.65	ENSDART00000150389	tmem168a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 168a
chr22_-_34979139 Show fit	1.65	ENSDART00000116455 ENSDART00000133537	arhgap19 NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 19
chr17_+_30591287 Show fit	1.65	ENSDART00000154243	si:dkey-190l8.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-190l8.2
chr16_+_25296389 Show fit	1.65	ENSDART00000114528	tbc1d31 NCBI UniProt ZFIN ENSEMBL Google Show fit	TBC1 domain family, member 31
chr12_-_7234915 Show fit	1.63	ENSDART00000048866	ipmkb NCBI UniProt ZFIN ENSEMBL Google Show fit	inositol polyphosphate multikinase b
chr21_-_13661631 Show fit	1.63	ENSDART00000184408	pnpla7a NCBI UniProt ZFIN ENSEMBL Google Show fit	patatin-like phospholipase domain containing 7a
chr14_-_15990361 Show fit	1.63	ENSDART00000168075	trim105 NCBI UniProt ZFIN ENSEMBL Google Show fit	tripartite motif containing 105
chr23_-_31400792 Show fit	1.63	ENSDART00000132736	lca5 NCBI UniProt ZFIN ENSEMBL Google Show fit	Leber congenital amaurosis 5
chr11_-_25257595 Show fit	1.62	ENSDART00000123567	snai1a NCBI UniProt ZFIN ENSEMBL Google Show fit	snail family zinc finger 1a
chr15_+_19990068 Show fit	1.62	ENSDART00000154033 ENSDART00000054428	zgc:112083 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:112083
chr16_-_13612650 Show fit	1.61	ENSDART00000080372	dbpb NCBI UniProt ZFIN ENSEMBL Google Show fit	D site albumin promoter binding protein b
chr16_+_48714048 Show fit	1.61	ENSDART00000148709 ENSDART00000150121	brd2b NCBI UniProt ZFIN ENSEMBL Google Show fit	bromodomain containing 2b
chr20_-_40360571 Show fit	1.61	ENSDART00000144768	smpdl3a NCBI UniProt ZFIN ENSEMBL Google Show fit	sphingomyelin phosphodiesterase, acid-like 3A
chr13_+_48617974 Show fit	1.60	ENSDART00000168596	si:ch1073-268j14.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-268j14.1
chr8_-_20862443 Show fit	1.58	ENSDART00000147267	si:ch211-133l5.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-133l5.8
chr18_+_3579829 Show fit	1.58	ENSDART00000158763 ENSDART00000182850 ENSDART00000162754 ENSDART00000178789 ENSDART00000172656	lrch3 NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine-rich repeats and calponin homology (CH) domain containing 3
chr20_+_36629173 Show fit	1.58	ENSDART00000161241	ephx1 NCBI UniProt ZFIN ENSEMBL Google Show fit	epoxide hydrolase 1, microsomal (xenobiotic)
chr21_+_19547806 Show fit	1.58	ENSDART00000159707 ENSDART00000184869 ENSDART00000181321 ENSDART00000058487 ENSDART00000058485	rai14 NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoic acid induced 14
chr11_+_6295370 Show fit	1.57	ENSDART00000139882	ranbp3a NCBI UniProt ZFIN ENSEMBL Google Show fit	RAN binding protein 3a
chr6_-_25384526 Show fit	1.57	ENSDART00000160544	PKN2 (1 of many) NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:153916
chr19_+_30450125 Show fit	1.56	ENSDART00000073704	si:ch211-215a10.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-215a10.4
chr3_-_29910547 Show fit	1.56	ENSDART00000151501	RUNDC1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-151m15.5
chr17_-_27200634 Show fit	1.56	ENSDART00000185332	asap3 NCBI UniProt ZFIN ENSEMBL Google Show fit	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr21_+_20901505 Show fit	1.55	ENSDART00000132741	c7b NCBI UniProt ZFIN ENSEMBL Google Show fit	complement component 7b
chr19_+_34230108 Show fit	1.55	ENSDART00000141950	galnt12 NCBI UniProt ZFIN ENSEMBL Google Show fit	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr16_+_30117798 Show fit	1.55	ENSDART00000135723 ENSDART00000000198	sema6e NCBI UniProt ZFIN ENSEMBL Google Show fit	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr20_+_27713210 Show fit	1.54	ENSDART00000132222	zbtb1 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger and BTB domain containing 1
chr8_-_29822527 Show fit	1.54	ENSDART00000167487	slc20a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 20 (phosphate transporter), member 2
chr25_-_29087925 Show fit	1.54	ENSDART00000171758	rpp25a NCBI UniProt ZFIN ENSEMBL Google Show fit	ribonuclease P and MRP subunit p25, a
chr21_-_13662237 Show fit	1.54	ENSDART00000091647 ENSDART00000151547	pnpla7a NCBI UniProt ZFIN ENSEMBL Google Show fit	patatin-like phospholipase domain containing 7a
chr3_+_19685873 Show fit	1.53	ENSDART00000006490	tlk2 NCBI UniProt ZFIN ENSEMBL Google Show fit	tousled-like kinase 2
chr15_-_25365570 Show fit	1.53	ENSDART00000152754	cluha NCBI UniProt ZFIN ENSEMBL Google Show fit	clustered mitochondria (cluA/CLU1) homolog a
chr11_-_30508843 Show fit	1.52	ENSDART00000101667 ENSDART00000179930	map4k3a NCBI UniProt ZFIN ENSEMBL Google Show fit	mitogen-activated protein kinase kinase kinase kinase 3a
chr14_-_34633960 Show fit	1.52	ENSDART00000128869 ENSDART00000179977	afap1l1a NCBI UniProt ZFIN ENSEMBL Google Show fit	actin filament associated protein 1-like 1a
chr25_-_18948816 Show fit	1.51	ENSDART00000091549	nt5dc3 NCBI UniProt ZFIN ENSEMBL Google Show fit	5'-nucleotidase domain containing 3
chr20_-_44090624 Show fit	1.51	ENSDART00000048978 ENSDART00000082283 ENSDART00000082276	runx2b NCBI UniProt ZFIN ENSEMBL Google Show fit	runt-related transcription factor 2b
chr23_-_24542952 Show fit	1.51	ENSDART00000088777	atp13a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase 13A2
chr7_+_52712807 Show fit	1.50	ENSDART00000174095 ENSDART00000174377 ENSDART00000174061 ENSDART00000174094 ENSDART00000110906 ENSDART00000174071 ENSDART00000174238	znf280d NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger protein 280D
chr8_+_7778770 Show fit	1.49	ENSDART00000171325	tfe3a NCBI UniProt ZFIN ENSEMBL Google Show fit	transcription factor binding to IGHM enhancer 3a
chr3_+_25907266 Show fit	1.49	ENSDART00000170324 ENSDART00000192633	tom1 NCBI UniProt ZFIN ENSEMBL Google Show fit	target of myb1 membrane trafficking protein
chr9_-_41025062 Show fit	1.48	ENSDART00000002053	pms1 NCBI UniProt ZFIN ENSEMBL Google Show fit	PMS1 homolog 1, mismatch repair system component
chr9_-_6991650 Show fit	1.48	ENSDART00000081718	slc9a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr8_+_26034623 Show fit	1.48	ENSDART00000004521 ENSDART00000142555	arih2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ariadne homolog 2 (Drosophila)
chr1_-_55238610 Show fit	1.47	ENSDART00000110818	FO704915.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr16_-_7828838 Show fit	1.47	ENSDART00000191434 ENSDART00000108653	tcaim NCBI UniProt ZFIN ENSEMBL Google Show fit	T cell activation inhibitor, mitochondrial
chr12_+_27061720 Show fit	1.47	ENSDART00000153426	srcap NCBI UniProt ZFIN ENSEMBL Google Show fit	Snf2-related CREBBP activator protein
chr5_+_62340799 Show fit	1.47	ENSDART00000074117	aspa NCBI UniProt ZFIN ENSEMBL Google Show fit	aspartoacylase
chr19_+_40122160 Show fit	1.47	ENSDART00000143966	si:ch211-173p18.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-173p18.3
chr21_-_43398122 Show fit	1.47	ENSDART00000050533	ccni2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin I family, member 2
chr22_+_10713713 Show fit	1.46	ENSDART00000122349	hiat1b NCBI UniProt ZFIN ENSEMBL Google Show fit	hippocampus abundant transcript 1b
chr18_-_13121983 Show fit	1.46	ENSDART00000092648	rxylt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribitol xylosyltransferase 1
chr11_+_15878343 Show fit	1.46	ENSDART00000167191 ENSDART00000171862 ENSDART00000163992 ENSDART00000170065	pank4 NCBI UniProt ZFIN ENSEMBL Google Show fit	pantothenate kinase 4
chr16_+_42667560 Show fit	1.46	ENSDART00000023452	dpy19l1l NCBI UniProt ZFIN ENSEMBL Google Show fit	dpy-19-like 1, like (H. sapiens)
chr9_-_41024438 Show fit	1.46	ENSDART00000157398	pms1 NCBI UniProt ZFIN ENSEMBL Google Show fit	PMS1 homolog 1, mismatch repair system component
chr1_+_29766725 Show fit	1.45	ENSDART00000054064	zc3h13 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger CCCH-type containing 13
chr5_+_44944778 Show fit	1.45	ENSDART00000130428 ENSDART00000044361 ENSDART00000128825 ENSDART00000124637 ENSDART00000126066 ENSDART00000177635	dmrt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	doublesex and mab-3 related transcription factor 1
chr5_+_61944453 Show fit	1.45	ENSDART00000134344	si:dkeyp-117b8.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-117b8.4
chr20_-_211920 Show fit	1.43	ENSDART00000104790	znf292b NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger protein 292b
chr5_-_66749535 Show fit	1.43	ENSDART00000132183	kat5b NCBI UniProt ZFIN ENSEMBL Google Show fit	K(lysine) acetyltransferase 5b
chr5_-_18961694 Show fit	1.43	ENSDART00000142531 ENSDART00000090521	ankle2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ankyrin repeat and LEM domain containing 2
chr25_+_33046060 Show fit	1.42	ENSDART00000165345	tln2b NCBI UniProt ZFIN ENSEMBL Google Show fit	talin 2b
chr15_-_1485086 Show fit	1.42	ENSDART00000191651	si:dkeyp-97b10.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-97b10.3
chr14_-_32824380 Show fit	1.42	ENSDART00000172791 ENSDART00000105745	inppl1b NCBI UniProt ZFIN ENSEMBL Google Show fit	inositol polyphosphate phosphatase-like 1b
chr19_+_42227400 Show fit	1.42	ENSDART00000131574 ENSDART00000135436	jtb NCBI UniProt ZFIN ENSEMBL Google Show fit	jumping translocation breakpoint
chr11_+_42765963 Show fit	1.42	ENSDART00000156080 ENSDART00000179888	tdrd3 NCBI UniProt ZFIN ENSEMBL Google Show fit	tudor domain containing 3
chr16_-_32975951 Show fit	1.42	ENSDART00000101969 ENSDART00000175149	me1 NCBI UniProt ZFIN ENSEMBL Google Show fit	malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_+_40094081 Show fit	1.41	ENSDART00000186054	si:ch73-174h16.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-174h16.4
chr16_+_19029297 Show fit	1.41	ENSDART00000115263 ENSDART00000114954	rapgef5b NCBI UniProt ZFIN ENSEMBL Google Show fit	Rap guanine nucleotide exchange factor (GEF) 5b
chr23_+_19594608 Show fit	1.41	ENSDART00000134865	slmapb NCBI UniProt ZFIN ENSEMBL Google Show fit	sarcolemma associated protein b
chr15_-_1590858 Show fit	1.41	ENSDART00000081875	nnr NCBI UniProt ZFIN ENSEMBL Google Show fit	nanor
chr5_-_68058168 Show fit	1.40	ENSDART00000177026	rnf167 NCBI UniProt ZFIN ENSEMBL Google Show fit	ring finger protein 167
chr16_-_30847192 Show fit	1.40	ENSDART00000191106 ENSDART00000128158	ptk2ab NCBI UniProt ZFIN ENSEMBL Google Show fit	protein tyrosine kinase 2ab
chr9_-_30494727 Show fit	1.40	ENSDART00000148729	si:dkey-229b18.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-229b18.3
chr21_-_43457554 Show fit	1.40	ENSDART00000085039	stk26 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine/threonine protein kinase 26
chr11_-_14102131 Show fit	1.40	ENSDART00000085158 ENSDART00000191962	tmem259 NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 259
chr7_+_15446229 Show fit	1.40	ENSDART00000046542	igf1rb NCBI UniProt ZFIN ENSEMBL Google Show fit	insulin-like growth factor 1b receptor
chr1_-_49947290 Show fit	1.40	ENSDART00000141476	sgms2 NCBI UniProt ZFIN ENSEMBL Google Show fit	sphingomyelin synthase 2
chr7_-_58178980 Show fit	1.40	ENSDART00000073635	nsmaf NCBI UniProt ZFIN ENSEMBL Google Show fit	neutral sphingomyelinase (N-SMase) activation associated factor
chr3_+_13929860 Show fit	1.40	ENSDART00000164179	syce2 NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptonemal complex central element protein 2
chr20_-_9428021 Show fit	1.39	ENSDART00000025330	rdh14b NCBI UniProt ZFIN ENSEMBL Google Show fit	retinol dehydrogenase 14b
chr7_-_46019756 Show fit	1.39	ENSDART00000162583	zgc:162297 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:162297
chr1_-_23370395 Show fit	1.38	ENSDART00000143014 ENSDART00000126785 ENSDART00000159138	pds5a NCBI UniProt ZFIN ENSEMBL Google Show fit	PDS5 cohesin associated factor A
chr2_-_37462462 Show fit	1.38	ENSDART00000145896	si:dkey-57k2.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-57k2.7
chr23_+_25172976 Show fit	1.38	ENSDART00000140789	si:dkey-151g10.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-151g10.3
chr20_-_7582936 Show fit	1.38	ENSDART00000083890	usp24 NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin specific peptidase 24
chr13_+_29925397 Show fit	1.38	ENSDART00000123482	cuedc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	CUE domain containing 2
chr10_-_39283883 Show fit	1.37	ENSDART00000023831	cry5 NCBI UniProt ZFIN ENSEMBL Google Show fit	cryptochrome circadian clock 5
chr13_+_40815012 Show fit	1.37	ENSDART00000016960	prkg1a NCBI UniProt ZFIN ENSEMBL Google Show fit	protein kinase, cGMP-dependent, type Ia
chr17_-_9962578 Show fit	1.37	ENSDART00000021942	eapp NCBI UniProt ZFIN ENSEMBL Google Show fit	e2f-associated phosphoprotein
chr3_+_29476085 Show fit	1.36	ENSDART00000184495 ENSDART00000181058	fam83fa NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 83, member Fa
chr8_-_4031121 Show fit	1.36	ENSDART00000169474 ENSDART00000163754	mtmr3 NCBI UniProt ZFIN ENSEMBL Google Show fit	myotubularin related protein 3
chr10_+_43406796 Show fit	1.35	ENSDART00000184337 ENSDART00000183034 ENSDART00000180623 ENSDART00000132486	rasa1b NCBI UniProt ZFIN ENSEMBL Google Show fit	RAS p21 protein activator (GTPase activating protein) 1b
chr21_+_13387965 Show fit	1.34	ENSDART00000134347	zgc:113162 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113162
chr9_+_33154841 Show fit	1.34	ENSDART00000132465	dopey2 NCBI UniProt ZFIN ENSEMBL Google Show fit	dopey family member 2
chr20_+_27712714 Show fit	1.33	ENSDART00000008306	zbtb1 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger and BTB domain containing 1
chr22_-_11054244 Show fit	1.33	ENSDART00000105823	insrb NCBI UniProt ZFIN ENSEMBL Google Show fit	insulin receptor b
chr1_-_23268013 Show fit	1.32	ENSDART00000146575	rfc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	replication factor C (activator 1) 1
chr13_+_36958086 Show fit	1.32	ENSDART00000024386	frmd6 NCBI UniProt ZFIN ENSEMBL Google Show fit	FERM domain containing 6
chr20_+_30378803 Show fit	1.32	ENSDART00000148242 ENSDART00000169140 ENSDART00000062441	rnaseh1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribonuclease H1
chr9_+_28140089 Show fit	1.31	ENSDART00000046880	plekhm3 NCBI UniProt ZFIN ENSEMBL Google Show fit	pleckstrin homology domain containing, family M, member 3
chr6_-_54348568 Show fit	1.30	ENSDART00000156501	zgc:101577 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:101577
chr10_+_41939963 Show fit	1.30	ENSDART00000126248	tmem120b NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 120B
chr23_-_17003533 Show fit	1.30	ENSDART00000080545	dnmt3bb.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr19_+_43669122 Show fit	1.30	ENSDART00000139151	si:ch211-193k19.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-193k19.1
chr5_-_25236340 Show fit	1.30	ENSDART00000162774	abca2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ATP-binding cassette, sub-family A (ABC1), member 2
chr3_-_26191960 Show fit	1.29	ENSDART00000113843	ypel3 NCBI UniProt ZFIN ENSEMBL Google Show fit	yippee-like 3
chr19_-_23249822 Show fit	1.29	ENSDART00000140665	grb10a NCBI UniProt ZFIN ENSEMBL Google Show fit	growth factor receptor-bound protein 10a
chr5_+_1965296 Show fit	1.29	ENSDART00000156224	dhx33 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr12_+_23991639 Show fit	1.29	ENSDART00000003143	psme4b NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome activator subunit 4b
chr9_+_37366973 Show fit	1.27	ENSDART00000016370	dirc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	disrupted in renal carcinoma 2

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1b+foxb2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
1.0	2.9	GO:1904869	positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.7	3.4	GO:1903722	regulation of centriole elongation(GO:1903722)
0.7	3.3	GO:0008592	regulation of Toll signaling pathway(GO:0008592)
0.6	3.5	GO:0035092	spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6	1.7	GO:0048917	posterior lateral line ganglion development(GO:0048917)
0.6	2.3	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.6	2.3	GO:0090299	regulation of neural crest formation(GO:0090299)
0.5	3.2	GO:1990108	protein linear deubiquitination(GO:1990108)
0.5	3.0	GO:0060965	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.5	1.5	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.5	1.4	GO:0030238	male sex determination(GO:0030238)
0.5	1.9	GO:1904184	regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.4	2.2	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.4	1.7	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4	1.2	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.4	1.9	GO:0035678	neuromast hair cell morphogenesis(GO:0035678)
0.4	2.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.4	1.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4	1.4	GO:1900120	regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.3	1.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.3	2.3	GO:1902975	cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3	2.5	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
0.3	0.9	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.3	0.9	GO:0018008	N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.3	1.2	GO:2000677	histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.3	0.9	GO:0035773	insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3	0.9	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3	1.1	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.3	2.0	GO:0031048	chromatin silencing by small RNA(GO:0031048)
0.3	0.8	GO:0042823	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3	1.7	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.3	1.9	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.3	1.3	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.3	0.8	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2	1.7	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2	1.7	GO:0048069	eye pigmentation(GO:0048069)
0.2	3.9	GO:0035268	protein mannosylation(GO:0035268) mannosylation(GO:0097502)
0.2	1.5	GO:0080009	mRNA methylation(GO:0080009)
0.2	2.4	GO:0006108	malate metabolic process(GO:0006108)
0.2	0.7	GO:0045191	histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.2	0.9	GO:0046168	NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2	0.7	GO:1903646	regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.2	2.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	1.6	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.2	1.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.2	0.9	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.2	1.9	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.2	1.0	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2	0.8	GO:0051876	pigment granule dispersal(GO:0051876)
0.2	0.6	GO:0070589	cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.2	1.0	GO:0010867	regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2	1.2	GO:1900028	wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.2	1.8	GO:0006857	oligopeptide transport(GO:0006857)
0.2	1.0	GO:0051972	regulation of telomerase activity(GO:0051972)
0.2	1.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	1.5	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.2	0.7	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.2	1.8	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.2	0.2	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.2	0.9	GO:0051659	maintenance of mitochondrion location(GO:0051659)
0.2	1.5	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.2	3.5	GO:0008078	mesodermal cell migration(GO:0008078)
0.2	1.5	GO:0006971	hypotonic response(GO:0006971) hypotonic salinity response(GO:0042539)
0.2	2.7	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.2	0.6	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.2	1.1	GO:0030728	ovulation(GO:0030728)
0.2	0.6	GO:0019532	oxalate transport(GO:0019532)
0.2	1.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.2	3.9	GO:0006884	cell volume homeostasis(GO:0006884)
0.2	0.6	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2	1.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	1.2	GO:0031113	regulation of microtubule polymerization(GO:0031113)
0.1	1.8	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	0.4	GO:0090134	mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1	1.0	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	1.2	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.7	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1	0.4	GO:0048785	hatching gland development(GO:0048785)
0.1	1.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.1	2.5	GO:0060079	excitatory postsynaptic potential(GO:0060079)
0.1	1.0	GO:0046958	nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1	0.6	GO:1904292	regulation of ERAD pathway(GO:1904292)
0.1	2.9	GO:0006298	mismatch repair(GO:0006298)
0.1	1.4	GO:0070307	lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1	1.5	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	2.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.6	GO:0030242	pexophagy(GO:0030242)
0.1	0.5	GO:0061010	gall bladder development(GO:0061010)
0.1	0.5	GO:1903059	regulation of lipoprotein metabolic process(GO:0050746) regulation of protein lipidation(GO:1903059)
0.1	1.7	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1	0.7	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	1.5	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	1.5	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.1	0.3	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1	1.1	GO:0061709	reticulophagy(GO:0061709)
0.1	0.4	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1	0.7	GO:0070650	actin filament bundle distribution(GO:0070650)
0.1	2.0	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.1	1.2	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.1	0.6	GO:0003272	endocardial cushion formation(GO:0003272)
0.1	0.4	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	4.8	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.1	0.4	GO:1902373	negative regulation of RNA catabolic process(GO:1902369) negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	1.5	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	1.9	GO:0022011	myelination in peripheral nervous system(GO:0022011)
0.1	0.8	GO:0033206	meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1	1.2	GO:0003139	secondary heart field specification(GO:0003139)
0.1	2.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.7	GO:0035627	ceramide transport(GO:0035627)
0.1	3.1	GO:0030488	tRNA methylation(GO:0030488)
0.1	5.3	GO:0000281	mitotic cytokinesis(GO:0000281)
0.1	2.0	GO:0021551	central nervous system morphogenesis(GO:0021551)
0.1	1.2	GO:0019730	antimicrobial humoral response(GO:0019730)
0.1	0.4	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.6	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.4	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1	0.3	GO:0099553	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1	1.0	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.1	3.5	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	0.7	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.1	1.4	GO:1902307	positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1	1.6	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.1	0.6	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1	1.1	GO:0007130	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1	1.5	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.1	0.8	GO:0003160	endocardium morphogenesis(GO:0003160)
0.1	0.3	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	1.8	GO:0051307	meiotic chromosome separation(GO:0051307)
0.1	0.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	9.2	GO:0006338	chromatin remodeling(GO:0006338)
0.1	4.2	GO:0034968	histone lysine methylation(GO:0034968)
0.1	1.1	GO:0018216	peptidyl-arginine methylation(GO:0018216)
0.1	0.4	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	1.2	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.1	1.9	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.1	1.4	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.1	1.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.7	GO:0071941	nitrogen cycle metabolic process(GO:0071941)
0.1	3.4	GO:1904029	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1	0.3	GO:0070166	enamel mineralization(GO:0070166)
0.1	0.7	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	1.4	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.1	0.4	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	1.7	GO:0007131	reciprocal meiotic recombination(GO:0007131)
0.1	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957) inositol phosphorylation(GO:0052746)
0.1	0.8	GO:0033198	response to ATP(GO:0033198)
0.1	1.0	GO:0007031	peroxisome organization(GO:0007031)
0.1	1.0	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1	1.6	GO:0019835	cytolysis(GO:0019835)
0.1	0.8	GO:0099560	synaptic membrane adhesion(GO:0099560)
0.1	0.8	GO:0032508	DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.1	1.8	GO:0050821	protein stabilization(GO:0050821)
0.1	0.9	GO:0035675	neuromast hair cell development(GO:0035675)
0.1	0.8	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	1.0	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.1	2.9	GO:1901800	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1	1.6	GO:0042073	intraciliary transport(GO:0042073)
0.1	0.7	GO:0000479	endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1	1.7	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.9	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	1.6	GO:0009636	response to toxic substance(GO:0009636)
0.0	0.2	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	1.2	GO:0071456	cellular response to hypoxia(GO:0071456)
0.0	0.8	GO:0016082	synaptic vesicle priming(GO:0016082)
0.0	0.8	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	1.2	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.6	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0	0.6	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	1.8	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	3.8	GO:0032272	negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0	0.6	GO:0036353	histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0	1.3	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	2.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.4	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.3	GO:0045905	positive regulation of translational termination(GO:0045905)
0.0	1.3	GO:0060037	pharyngeal system development(GO:0060037)
0.0	1.0	GO:0035329	hippo signaling(GO:0035329)
0.0	1.0	GO:0048264	determination of ventral identity(GO:0048264)
0.0	1.0	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	3.5	GO:0007030	Golgi organization(GO:0007030)
0.0	1.0	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.0	0.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	1.1	GO:0006400	tRNA modification(GO:0006400)
0.0	0.9	GO:0043631	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0	0.7	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.7	GO:0002574	thrombocyte differentiation(GO:0002574)
0.0	0.2	GO:0031179	peptide modification(GO:0031179)
0.0	2.1	GO:0051607	defense response to virus(GO:0051607)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.9	GO:0000154	rRNA modification(GO:0000154)
0.0	2.3	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.2	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	1.9	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.8	GO:0050870	positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0	3.3	GO:0031098	stress-activated protein kinase signaling cascade(GO:0031098)
0.0	1.0	GO:0030261	chromosome condensation(GO:0030261)
0.0	1.2	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	0.6	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.6	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	2.7	GO:0006413	translational initiation(GO:0006413)
0.0	0.2	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.0	0.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.4	GO:0060078	regulation of postsynaptic membrane potential(GO:0060078)
0.0	2.9	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
0.0	0.6	GO:0032402	melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0	0.9	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	2.3	GO:0090504	epiboly(GO:0090504)
0.0	0.5	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	1.8	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.1	GO:0006043	glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0	0.5	GO:0016925	protein sumoylation(GO:0016925)
0.0	1.8	GO:0016573	histone acetylation(GO:0016573)
0.0	0.3	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.5	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.7	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.7	GO:0035088	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.3	GO:0032465	regulation of cytokinesis(GO:0032465)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	1.6	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.8	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.1	GO:0007032	endosome organization(GO:0007032)
0.0	1.8	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	1.7	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	3.3	GO:0006869	lipid transport(GO:0006869)
0.0	0.3	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	1.4	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.5	GO:0007098	centrosome cycle(GO:0007098)
0.0	1.0	GO:0007281	germ cell development(GO:0007281)
0.0	0.8	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.0	0.1	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0	0.4	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0009651	response to salt stress(GO:0009651)
0.0	0.4	GO:0051781	positive regulation of cell division(GO:0051781)
0.0	0.3	GO:0017121	phospholipid scrambling(GO:0017121)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.5	GO:1990111	spermatoproteasome complex(GO:1990111)
0.7	2.7	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.6	2.4	GO:0043073	germ cell nucleus(GO:0043073)
0.5	2.7	GO:0005899	insulin receptor complex(GO:0005899)
0.5	3.3	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4	1.5	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3	1.4	GO:0000801	central element(GO:0000801)
0.3	1.6	GO:0000811	GINS complex(GO:0000811)
0.3	2.9	GO:0032300	mismatch repair complex(GO:0032300)
0.3	1.1	GO:0097268	cytoophidium(GO:0097268)
0.3	1.1	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.2	0.7	GO:0072380	TRC complex(GO:0072380)
0.2	1.5	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.2	2.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.2	1.0	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.2	0.9	GO:0034657	GID complex(GO:0034657)
0.2	1.2	GO:0000439	core TFIIH complex(GO:0000439)
0.2	2.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	0.7	GO:0044326	dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.2	3.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	0.7	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	0.6	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2	2.3	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2	0.9	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	0.5	GO:0005828	kinetochore microtubule(GO:0005828)
0.2	0.5	GO:0031213	RSF complex(GO:0031213)
0.1	1.5	GO:0000812	Swr1 complex(GO:0000812)
0.1	0.4	GO:0034457	Mpp10 complex(GO:0034457)
0.1	1.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	0.7	GO:0055087	Ski complex(GO:0055087)
0.1	0.9	GO:0030897	HOPS complex(GO:0030897)
0.1	1.0	GO:0000796	condensin complex(GO:0000796)
0.1	0.8	GO:0070695	FHF complex(GO:0070695)
0.1	0.9	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.6	GO:0071203	WASH complex(GO:0071203)
0.1	1.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	2.5	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.0	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	1.6	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.7	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	1.0	GO:0070449	elongin complex(GO:0070449)
0.1	0.6	GO:0030914	STAGA complex(GO:0030914)
0.1	1.9	GO:0032420	stereocilium(GO:0032420)
0.1	1.9	GO:0032039	integrator complex(GO:0032039)
0.1	0.6	GO:0070847	core mediator complex(GO:0070847)
0.1	2.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	0.5	GO:0033557	Slx1-Slx4 complex(GO:0033557)
0.1	0.8	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	1.8	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	1.5	GO:0030686	90S preribosome(GO:0030686)
0.1	1.5	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.7	GO:0032021	NELF complex(GO:0032021)
0.1	0.3	GO:0017177	glucosidase II complex(GO:0017177)
0.1	2.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	0.3	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	0.9	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	3.0	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	0.5	GO:0016586	RSC complex(GO:0016586)
0.1	1.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	0.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.7	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	1.0	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	2.9	GO:0030496	midbody(GO:0030496)
0.1	0.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	1.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.8	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	3.9	GO:0005871	kinesin complex(GO:0005871)
0.0	3.5	GO:0005814	centriole(GO:0005814)
0.0	0.4	GO:0016272	prefoldin complex(GO:0016272)
0.0	1.0	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0	5.6	GO:0005925	focal adhesion(GO:0005925)
0.0	2.0	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.3	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.8	GO:0072686	mitotic spindle(GO:0072686)
0.0	3.6	GO:0036464	cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0	1.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.5	GO:0071782	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0	10.0	GO:0005730	nucleolus(GO:0005730)
0.0	4.4	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	2.8	GO:0005819	spindle(GO:0005819)
0.0	0.6	GO:0042555	MCM complex(GO:0042555)
0.0	0.6	GO:0070822	Sin3-type complex(GO:0070822)
0.0	1.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	2.7	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	2.8	GO:0043197	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	1.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.4	GO:0044545	NSL complex(GO:0044545)
0.0	6.8	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.9	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.7	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0098839	postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0	0.4	GO:0038201	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0	0.6	GO:0008305	integrin complex(GO:0008305)
0.0	0.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.7	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0043514	interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0	0.7	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	1.9	GO:0005813	centrosome(GO:0005813)
0.0	1.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.5	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.9	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	2.0	GO:0005681	spliceosomal complex(GO:0005681)
0.0	1.3	GO:0005884	actin filament(GO:0005884)
0.0	0.4	GO:0032589	neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0	0.3	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.8	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	1.0	GO:0005581	collagen trimer(GO:0005581)
0.0	3.9	GO:1990904	ribonucleoprotein complex(GO:1990904)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.8	2.5	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.7	2.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.6	1.9	GO:0001160	transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.6	2.4	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.6	3.4	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5	2.7	GO:0043560	insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.5	1.6	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5	1.6	GO:0033961	cis-stilbene-oxide hydrolase activity(GO:0033961)
0.5	1.9	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5	1.4	GO:0031701	angiotensin receptor binding(GO:0031701)
0.5	1.9	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5	1.4	GO:0003913	DNA photolyase activity(GO:0003913)
0.4	1.8	GO:0047464	heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.4	1.2	GO:0042806	fucose binding(GO:0042806)
0.4	2.0	GO:0035197	siRNA binding(GO:0035197)
0.4	3.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.4	3.5	GO:0016504	peptidase activator activity(GO:0016504)
0.3	3.8	GO:0043142	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.3	1.7	GO:1990756	protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3	3.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3	1.0	GO:0004736	pyruvate carboxylase activity(GO:0004736)
0.3	1.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.3	1.2	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3	0.9	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.3	1.2	GO:0031151	histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.3	1.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.3	0.9	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3	1.1	GO:0003883	CTP synthase activity(GO:0003883)
0.3	1.6	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.3	3.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3	2.6	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3	1.5	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.2	1.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.2	1.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	0.7	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2	0.9	GO:0005463	UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.2	0.9	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2	1.4	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.2	0.9	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.2	1.5	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	3.1	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.2	1.2	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2	1.1	GO:0015616	DNA translocase activity(GO:0015616)
0.2	1.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2	0.9	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2	1.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2	1.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	1.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2	1.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.2	0.9	GO:0046592	polyamine oxidase activity(GO:0046592)
0.2	0.9	GO:0043295	glutathione binding(GO:0043295)
0.2	2.4	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2	1.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.2	0.7	GO:0034511	U3 snoRNA binding(GO:0034511)
0.2	2.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2	1.0	GO:0022889	serine transmembrane transporter activity(GO:0022889)
0.2	2.9	GO:0030983	mismatched DNA binding(GO:0030983)
0.2	2.3	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2	2.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	0.5	GO:0032574	5'-3' RNA helicase activity(GO:0032574)
0.2	3.9	GO:0015377	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2	1.9	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.9	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	2.9	GO:0008171	O-methyltransferase activity(GO:0008171)
0.1	1.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.7	GO:0035620	ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1	3.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	2.4	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.9	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	1.5	GO:0015385	monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	3.2	GO:0031267	small GTPase binding(GO:0031267)
0.1	2.7	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.1	1.0	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.1	1.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.8	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	2.2	GO:0003785	actin monomer binding(GO:0003785)
0.1	1.5	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.6	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	0.4	GO:0004419	hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1	1.5	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	1.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.7	GO:0098809	nitrite reductase activity(GO:0098809)
0.1	2.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	1.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	0.6	GO:0070628	proteasome binding(GO:0070628)
0.1	1.5	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.4	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.9	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	1.4	GO:0019869	chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1	0.3	GO:0030626	U12 snRNA binding(GO:0030626)
0.1	0.6	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	1.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	1.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.7	GO:0051920	peroxiredoxin activity(GO:0051920)
0.1	5.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.3	GO:0008488	gamma-glutamyl carboxylase activity(GO:0008488)
0.1	2.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	1.1	GO:0002039	p53 binding(GO:0002039)
0.1	6.4	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1	0.4	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	2.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	1.6	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.8	GO:0043495	protein anchor(GO:0043495)
0.1	0.2	GO:0051766	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1	0.8	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.4	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	4.4	GO:0003678	DNA helicase activity(GO:0003678)
0.1	2.1	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.7	GO:0005537	mannose binding(GO:0005537)
0.1	0.2	GO:0051117	ATPase binding(GO:0051117)
0.1	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.4	GO:0008515	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	1.7	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	0.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.5	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	2.3	GO:0004521	endoribonuclease activity(GO:0004521)
0.0	1.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.5	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	4.8	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	1.6	GO:0030674	protein binding, bridging(GO:0030674)
0.0	3.8	GO:0030276	clathrin binding(GO:0030276)
0.0	6.6	GO:0042393	histone binding(GO:0042393)
0.0	1.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.3	GO:0099530	G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0	1.5	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:1902945	metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0	0.4	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	3.7	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	1.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.4	GO:0022851	benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0	3.5	GO:0005319	lipid transporter activity(GO:0005319)
0.0	0.1	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.0	5.6	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.2	GO:0000048	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0	0.6	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.7	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.3	GO:0031994	insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0	0.7	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	1.5	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.6	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.4	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	8.2	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0042164	interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0	0.3	GO:0030515	snoRNA binding(GO:0030515)
0.0	1.7	GO:0004386	helicase activity(GO:0004386)
0.0	0.2	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.7	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	1.1	GO:0019905	syntaxin binding(GO:0019905)
0.0	5.3	GO:0016887	ATPase activity(GO:0016887)
0.0	0.6	GO:0000049	tRNA binding(GO:0000049)
0.0	0.4	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	1.4	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.2	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.5	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.5	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	1.0	GO:0003774	motor activity(GO:0003774)
0.0	0.5	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.5	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	4.5	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.7	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.3	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0030165	PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	2.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	2.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	4.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	2.2	PID ARF6 PATHWAY	Arf6 signaling events
0.1	2.2	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	2.2	PID RHOA PATHWAY	RhoA signaling pathway
0.1	1.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	0.3	ST GAQ PATHWAY	G alpha q Pathway
0.1	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	2.4	PID LKB1 PATHWAY	LKB1 signaling events
0.1	2.6	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	1.0	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	2.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.7	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	2.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	2.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	2.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.2	1.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.2	0.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	3.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	0.9	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	2.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	2.2	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1	1.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	4.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	0.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	1.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.9	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	7.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	2.3	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	3.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.4	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.6	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN

Results for foxb1b+foxb2

Z-value: 2.44

Motif logo

Transcription factors associated with foxb1b+foxb2

Activity-expression correlation:

Activity profile of foxb1b+foxb2 motif

Sorted Z-values of foxb1b+foxb2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1b+foxb2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: