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PRJNA195909:zebrafish embryo and larva development
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Results for etv7
Z-value: 1.36
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Transcription factors associated with etv7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| etv7 | dr11_v1_chr23_-_5101847_5101847 | -0.56 | 1.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr23_+_32101202 Show fit | 2.30 |
ENSDART00000000992
|
zgc:56699 |
|
| chr23_+_32101361 Show fit | 2.18 |
ENSDART00000138849
|
zgc:56699 |
|
| chr7_-_58826164 Show fit | 1.66 |
ENSDART00000171095
|
SRY (sex determining region Y)-box 32 |
|
| chr7_+_46019780 Show fit | 1.54 |
ENSDART00000163991
|
cyclin E1 |
|
| chr13_-_4979029 Show fit | 1.26 |
ENSDART00000132931
|
nucleolar and coiled-body phosphoprotein 1 |
|
| chr14_-_10617923 Show fit | 1.21 |
ENSDART00000133723
ENSDART00000131939 ENSDART00000136649 |
si:dkey-92i17.2 |
|
| chr16_+_13860299 Show fit | 1.15 |
ENSDART00000121998
|
glutamate-rich WD repeat containing 1 |
|
| chr5_+_28497956 Show fit | 1.11 |
ENSDART00000191935
|
notochord formation related |
|
| chr10_+_17747880 Show fit | 0.97 |
ENSDART00000135044
|
phosphatidylinositol glycan anchor biosynthesis, class O |
|
| chr1_-_354115 Show fit | 0.95 |
ENSDART00000141590
ENSDART00000098627 |
protein S |
Network of associatons between targets according to the STRING database.
First level regulatory network of etv7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.2 | 1.7 | GO:0003262 | endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262) |
| 0.1 | 1.6 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 1.5 | GO:0000082 | G1/S transition of mitotic cell cycle(GO:0000082) |
| 0.1 | 1.3 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.1 | 1.2 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 1.2 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 1.1 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
| 0.3 | 1.0 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 1.0 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | GO:0005730 | nucleolus(GO:0005730) |
| 0.4 | 1.5 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
| 0.2 | 1.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.2 | 0.7 | GO:0043614 | multi-eIF complex(GO:0043614) |
| 0.0 | 0.7 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.1 | 0.6 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.1 | 0.6 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.0 | 0.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.5 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 1.3 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.1 | 1.2 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 1.2 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.2 | 1.0 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.0 | 1.0 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.0 | 0.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 0.6 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.0 | 0.6 | GO:0070122 | isopeptidase activity(GO:0070122) |
| 0.0 | 0.6 | GO:0019003 | GDP binding(GO:0019003) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 1.4 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 1.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.3 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.2 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 1.3 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.1 | 1.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.2 | 1.0 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 1.0 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.7 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 0.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.4 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.4 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |