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PRJNA195909:zebrafish embryo and larva development
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Results for eomesa
Z-value: 2.00
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Transcription factors associated with eomesa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| eomesa | dr11_v1_chr19_-_868187_868187 | 0.94 | 1.7e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_+_19596214 Show fit | 6.26 |
ENSDART00000183110
|
|
|
| chr10_-_25217347 Show fit | 4.63 |
ENSDART00000036906
|
karyopherin alpha 7 (importin alpha 8) |
|
| chr15_-_35112937 Show fit | 4.28 |
ENSDART00000154565
ENSDART00000099642 |
zgc:77118 |
|
| chr19_-_867071 Show fit | 4.20 |
ENSDART00000122257
|
eomesodermin homolog a |
|
| chr19_-_27564458 Show fit | 4.20 |
ENSDART00000123155
|
si:dkeyp-46h3.6 |
|
| chr10_+_19595009 Show fit | 3.92 |
ENSDART00000112276
|
zgc:173837 |
|
| chr22_+_25693295 Show fit | 3.81 |
ENSDART00000123888
ENSDART00000150783 |
si:dkeyp-98a7.4 si:dkeyp-98a7.3 |
|
| chr22_+_25715925 Show fit | 3.79 |
ENSDART00000150650
|
si:dkeyp-98a7.7 |
|
| chr22_+_25687525 Show fit | 3.76 |
ENSDART00000135717
|
si:dkeyp-98a7.3 |
|
| chr22_+_25681911 Show fit | 3.75 |
ENSDART00000113381
|
si:dkeyp-98a7.3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of eomesa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 1.4 | 4.2 | GO:0060571 | invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571) |
| 0.0 | 3.3 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.1 | 3.1 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.2 | 3.0 | GO:0048798 | swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798) |
| 0.1 | 2.7 | GO:0070654 | sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399) |
| 0.4 | 2.6 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.0 | 2.3 | GO:0043534 | blood vessel endothelial cell migration(GO:0043534) |
| 0.2 | 2.2 | GO:0001765 | membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.5 | 1.8 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.2 | 2.7 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 2.7 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 2.6 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 2.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 2.0 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.4 | 1.8 | GO:1990923 | PET complex(GO:1990923) |
| 0.3 | 1.7 | GO:0034657 | GID complex(GO:0034657) |
| 0.1 | 1.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 1.5 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 25.7 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.3 | 4.6 | GO:0061608 | nuclear import signal receptor activity(GO:0061608) |
| 0.2 | 3.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.3 | 3.0 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.0 | 2.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 2.6 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 2.2 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.3 | 1.8 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.2 | 1.8 | GO:0034584 | piRNA binding(GO:0034584) |
| 0.1 | 1.6 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.1 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.8 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.8 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.7 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.7 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 0.6 | PID RHOA PATHWAY | RhoA signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 2.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.3 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |