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PRJNA195909:zebrafish embryo and larva development

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Results for en1b_en2a+en2b_gbx1_emx1

Z-value: 0.56

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Transcription factors associated with en1b_en2a+en2b_gbx1_emx1

Gene Symbol Gene ID Gene Info
ENSDARG00000098730 engrailed homeobox 1b
ENSDARG00000026599 engrailed homeobox 2a
ENSDARG00000038868 engrailed homeobox 2b
ENSDARG00000115233 engrailed homeobox 2a
ENSDARG00000071418 gastrulation brain homeobox 1
ENSDARG00000039569 empty spiracles homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
en1bdr11_v1_chr1_+_7679328_7679328-0.956.4e-05Click!
emx1dr11_v1_chr13_+_15004398_15004398-0.901.1e-03Click!
en2adr11_v1_chr7_-_40993456_40993456-0.882.0e-03Click!
en2bdr11_v1_chr2_+_29976419_29976419-0.836.1e-03Click!
gbx1dr11_v1_chr24_+_34113424_34113424-0.206.1e-01Click!

Activity profile of en1b_en2a+en2b_gbx1_emx1 motif

Sorted Z-values of en1b_en2a+en2b_gbx1_emx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 2.27 ENSDART00000021620
claudin d
chr10_-_21362071 1.61 ENSDART00000125167
avidin
chr9_-_35633827 1.61 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr10_-_21362320 1.60 ENSDART00000189789
avidin
chr20_-_23426339 1.30 ENSDART00000004625
zygote arrest 1
chr10_+_6884627 1.18 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr1_-_55248496 1.15 ENSDART00000098615
nanos homolog 3
chr2_+_6253246 1.13 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr24_+_1023839 1.09 ENSDART00000082526
zgc:111976
chr18_-_40708537 1.04 ENSDART00000077577
si:ch211-132b12.8
chr10_-_44560165 1.01 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr4_+_306036 0.97 ENSDART00000103659
mesogenin 1
chr10_-_34002185 0.93 ENSDART00000046599
zygote arrest 1-like
chr24_+_12835935 0.93 ENSDART00000114762
nanog homeobox
chr11_-_44801968 0.89 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr24_-_9979342 0.86 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr14_+_34490445 0.85 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr19_+_31585917 0.82 ENSDART00000132182
geminin, DNA replication inhibitor
chr22_+_17828267 0.76 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr11_-_1550709 0.65 ENSDART00000110097
si:ch73-303b9.1
chr10_+_6884123 0.64 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr5_-_30074332 0.62 ENSDART00000147963
beta-carotene oxygenase 2a
chr5_-_15283509 0.61 ENSDART00000052712
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr22_+_4488454 0.60 ENSDART00000170620
cortexin 1
chr1_-_18811517 0.58 ENSDART00000142026
si:dkey-167i21.2
chr16_-_42056137 0.57 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr8_-_23780334 0.56 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr17_+_16046132 0.56 ENSDART00000155005
si:ch73-204p21.2
chr2_-_15324837 0.54 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr10_+_17371356 0.53 ENSDART00000122663
signal peptide peptidase 3
chr10_+_19596214 0.53 ENSDART00000183110

chr17_+_16046314 0.51 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr11_+_37638873 0.51 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
SH2 domain containing 5
chr9_+_54695981 0.51 ENSDART00000183605
RAB9A, member RAS oncogene family
chr23_+_42254960 0.50 ENSDART00000102980
zinc finger, CCHC domain containing 11
chr25_+_35891342 0.50 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr5_+_68807170 0.49 ENSDART00000017849
hairy and enhancer of split related-7
chr12_-_48168135 0.48 ENSDART00000186624
phosphatase domain containing, paladin 1a
chr14_-_8940499 0.48 ENSDART00000129030
zgc:153681
chr12_-_14143344 0.46 ENSDART00000152742
bucky ball 2-like
chr10_-_35257458 0.45 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr12_+_46582727 0.45 ENSDART00000149326
Usher syndrome 1Gb (autosomal recessive)
chr2_-_57076687 0.45 ENSDART00000161523
solute carrier family 25, member 42
chr10_-_13343831 0.45 ENSDART00000135941
interleukin 11 receptor, alpha
chr9_+_18829360 0.45 ENSDART00000006514
general transcription factor IIF, polypeptide 2b
chr8_-_1838315 0.45 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr5_-_68779747 0.44 ENSDART00000192636
ENSDART00000188039
methylphosphate capping enzyme
chr5_-_68795063 0.44 ENSDART00000016307
hairy-related 1
chr3_+_22035863 0.43 ENSDART00000177169
cell division cycle 27
chr13_-_21660203 0.43 ENSDART00000100925
mix-type homeobox gene 1
chr20_-_6532462 0.41 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr24_-_2450597 0.41 ENSDART00000188080
ENSDART00000093331
ras responsive element binding protein 1a
chr6_-_43283122 0.41 ENSDART00000186022
FERM domain containing 4Ba
chr6_+_28208973 0.39 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
si:ch73-14h10.2
chr18_-_20458840 0.39 ENSDART00000177125
kinesin family member 23
chr2_-_38287987 0.39 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr8_-_53044300 0.38 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr6_+_40922572 0.37 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr21_-_31013817 0.37 ENSDART00000065504
nuclear cap binding subunit 3
chr23_-_35790235 0.36 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
major facilitator superfamily domain containing 5
chr20_+_46513651 0.36 ENSDART00000152977
zinc finger CCCH-type containing 14
chr10_-_32494499 0.36 ENSDART00000129395
UV radiation resistance associated gene
chr2_+_20793982 0.35 ENSDART00000014785
proteoglycan 4a
chr23_+_2728095 0.35 ENSDART00000066086
zgc:114123
chr6_-_12275836 0.35 ENSDART00000189980
plakophilin 4
chr16_+_47207691 0.35 ENSDART00000062507
islet cell autoantigen 1
chr11_+_18183220 0.35 ENSDART00000113468

chr19_-_20403507 0.35 ENSDART00000052603
ENSDART00000137590
deleted in azoospermia-like
chr11_-_6452444 0.35 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr2_+_41526904 0.34 ENSDART00000127520
activin A receptor, type 1 like
chr2_+_56213694 0.34 ENSDART00000162582
upf1 regulator of nonsense transcripts homolog (yeast)
chr3_-_23643751 0.34 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr18_+_20560616 0.33 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr5_+_63302660 0.33 ENSDART00000142131
si:ch73-376l24.2
chr5_+_6954162 0.33 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr17_+_8799451 0.32 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr24_+_39518774 0.32 ENSDART00000132939
defective in cullin neddylation 1 domain containing 3
chr23_-_17003533 0.32 ENSDART00000080545
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr22_+_9003090 0.32 ENSDART00000106414
ribonuclease/angiogenin inhibitor 1
chr14_-_33945692 0.32 ENSDART00000168546
ENSDART00000189778
zinc finger, DHHC-type containing 24
chr1_+_35985813 0.32 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr9_-_53666031 0.32 ENSDART00000126314
protocadherin 8
chr24_-_34680956 0.32 ENSDART00000171009
catenin (cadherin-associated protein), alpha 1
chr7_+_23515966 0.31 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr7_-_51368681 0.31 ENSDART00000146385
Rho GTPase activating protein 36
chr9_-_3934963 0.31 ENSDART00000062336
ubiquitin protein ligase E3 component n-recognin 3
chr19_+_2631565 0.30 ENSDART00000171487
family with sequence similarity 126, member A
chr12_-_33357655 0.30 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr23_+_27782071 0.30 ENSDART00000131379
lysine (K)-specific methyltransferase 2D
chr23_-_31913069 0.30 ENSDART00000135526
mitochondrial fission regulator 2
chr7_+_34592526 0.30 ENSDART00000173959
formin homology 2 domain containing 1
chr19_+_4968947 0.29 ENSDART00000003634
ENSDART00000134808
StAR-related lipid transfer (START) domain containing 3
chr5_-_62925282 0.29 ENSDART00000188048
sperm antigen with calponin homology and coiled-coil domains 1
chr10_-_32494304 0.29 ENSDART00000028161
UV radiation resistance associated gene
chr6_-_2133737 0.29 ENSDART00000158535
V-set and transmembrane domain containing 2 like
chr17_+_49500820 0.29 ENSDART00000170306
apoptosis resistant E3 ubiquitin protein ligase 1
chr4_+_11723852 0.29 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr7_-_51773166 0.28 ENSDART00000054591
bone morphogenetic protein 15
chr6_+_21001264 0.28 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr4_+_25917915 0.28 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr2_-_32825917 0.28 ENSDART00000180409
pre-mRNA processing factor 4Ba
chr3_-_15210491 0.27 ENSDART00000037906
HIRA interacting protein 3
chr16_+_28994709 0.27 ENSDART00000088023
gon-4-like (C. elegans)
chr13_-_35808904 0.27 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr17_+_21902058 0.27 ENSDART00000142178
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr17_-_21162821 0.27 ENSDART00000157283
abhydrolase domain containing 12
chr6_-_37744430 0.27 ENSDART00000150177
ENSDART00000149722
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr25_-_32869794 0.26 ENSDART00000162784
transmembrane protein 266
chr5_+_28497956 0.26 ENSDART00000191935
notochord formation related
chr4_+_13586689 0.26 ENSDART00000067161
ENSDART00000138201
transportin 3
chr8_-_52562672 0.26 ENSDART00000159333
ENSDART00000159974
si:ch73-199g24.2
chr9_-_50000144 0.26 ENSDART00000123416
sodium channel, voltage-gated, type I, alpha
chr5_-_19006290 0.26 ENSDART00000137022
golgin A3
chr7_+_24528430 0.26 ENSDART00000133022
si:dkeyp-75h12.2
chr16_-_41714988 0.26 ENSDART00000138798
centrosomal protein 85
chr24_-_10006158 0.26 ENSDART00000106244
zgc:171750
chr19_-_8768564 0.25 ENSDART00000170416
si:ch73-350k19.1
chr7_-_12464412 0.25 ENSDART00000178723
ADAMTS-like 3
chr15_-_16177603 0.25 ENSDART00000156352
si:ch211-259g3.4
chr24_-_24724233 0.25 ENSDART00000127044
ENSDART00000012399
armadillo repeat containing 1
chr20_-_51831657 0.25 ENSDART00000165076
melanoma inhibitory activity family, member 3
chr24_+_40905100 0.25 ENSDART00000167854
sodium channel, voltage gated, type XII, alpha b
chr19_-_5805923 0.25 ENSDART00000134340
si:ch211-264f5.8
chr5_-_9625459 0.25 ENSDART00000143347
SH2B adaptor protein 3
chr16_-_41488023 0.25 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr20_-_14114078 0.24 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr17_-_40956035 0.24 ENSDART00000124715
si:dkey-16j16.4
chr14_+_26247319 0.24 ENSDART00000192793
coiled-coil domain containing 69
chr3_+_18807006 0.24 ENSDART00000180091
transportin 2 (importin 3, karyopherin beta 2b)
chr3_+_22443313 0.24 ENSDART00000156450
WNK lysine deficient protein kinase 4b
chr5_-_66397688 0.24 ENSDART00000161483
huntingtin interacting protein 1 related b
chr8_-_37249813 0.24 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
RNA binding motif protein 39b
chr17_-_20118145 0.24 ENSDART00000149737
ENSDART00000165606
ryanodine receptor 2b (cardiac)
chr13_+_38814521 0.23 ENSDART00000110976
collagen, type XIX, alpha 1
chr11_-_42134968 0.23 ENSDART00000187115

chr15_-_43284021 0.23 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr14_+_32942063 0.23 ENSDART00000187705
ligand of numb-protein X 2b
chr1_-_47071979 0.23 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr10_-_33297864 0.23 ENSDART00000163360
PR/SET domain 15
chr20_-_37813863 0.23 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr5_-_67629263 0.22 ENSDART00000133753
zinc finger and BTB domain containing 20
chr24_-_25144441 0.22 ENSDART00000152104
pleckstrin homology-like domain, family B, member 2b
chr17_+_12813316 0.22 ENSDART00000155629
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr12_+_47698356 0.22 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr9_+_17983463 0.22 ENSDART00000182150
A kinase (PRKA) anchor protein 11
chr8_+_49117518 0.22 ENSDART00000079631
RAD21 cohesin complex component like 1
chr7_-_19642417 0.21 ENSDART00000160936
si:ch211-212k18.4
chr22_-_23267893 0.21 ENSDART00000105613
si:dkey-121a9.3
chr17_+_24821627 0.21 ENSDART00000112389
WD repeat domain 43
chr19_-_20430892 0.21 ENSDART00000111409
TBC1 domain family, member 5
chr15_-_590787 0.21 ENSDART00000189367
si:ch73-144d13.5
chr9_+_29548195 0.21 ENSDART00000176057
ring finger protein 17
chr5_-_68782641 0.21 ENSDART00000141699
methylphosphate capping enzyme
chr24_-_30843250 0.21 ENSDART00000162920
polypyrimidine tract binding protein 2a
chr1_-_23308225 0.20 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr15_+_28410664 0.20 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr23_+_28322986 0.20 ENSDART00000134710
baculoviral IAP repeat containing 5b
chr5_-_23715861 0.20 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr6_-_40922971 0.20 ENSDART00000155363
SFI1 centrin binding protein
chr8_+_45334255 0.20 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr20_-_51831816 0.20 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr8_+_11325310 0.20 ENSDART00000142577
frataxin
chr9_-_21460164 0.20 ENSDART00000133469
zinc finger, MYM-type 2
chr21_-_15200556 0.20 ENSDART00000141809
splicing factor SWAP
chr6_+_41191482 0.20 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr5_-_67241633 0.20 ENSDART00000114783
CAP-GLY domain containing linker protein 1a
chr13_+_22295905 0.20 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr17_-_3815693 0.20 ENSDART00000161207
phospholipase C beta 4
chr19_-_5865766 0.20 ENSDART00000191007

chr20_+_27087539 0.20 ENSDART00000062094
transmembrane protein 251
chr15_+_17345609 0.20 ENSDART00000111753
vacuole membrane protein 1
chr3_+_32832538 0.20 ENSDART00000139410
CD2 (cytoplasmic tail) binding protein 2
chr23_+_42272588 0.20 ENSDART00000164907

chr9_-_38021889 0.20 ENSDART00000183482
ENSDART00000124333
adenylate cyclase 5
chr3_-_697363 0.20 ENSDART00000186520
diverse immunoglobulin domain-containing protein 1.3-4
chr20_-_20324792 0.20 ENSDART00000042376
small nuclear RNA activating complex, polypeptide 1a
chr19_+_12406583 0.20 ENSDART00000013865
ENSDART00000151535
SEH1-like (S. cerevisiae)
chr19_-_18313303 0.20 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
chr5_+_19933356 0.19 ENSDART00000088819
ankyrin repeat domain 13A
chr20_+_29209926 0.19 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr6_-_19665114 0.19 ENSDART00000168985
ubiquitin specific peptidase 43a
chr4_-_63848305 0.19 ENSDART00000097308

chr25_-_27621268 0.19 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr18_+_44849809 0.19 ENSDART00000097328
ADP-ribosylation factor GTPase activating protein 2
chr24_+_14581864 0.19 ENSDART00000134536
thiamine triphosphatase
chr24_-_10021341 0.19 ENSDART00000137250
zgc:173856
chr13_+_40501455 0.19 ENSDART00000114985
heparanase 2
chr8_-_52909850 0.19 ENSDART00000161943
nuclear receptor subfamily 6, group A, member 1a
chr24_+_19415124 0.19 ENSDART00000186931
sulfatase 1
chr13_+_33688474 0.18 ENSDART00000161465

chr23_-_31913231 0.18 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr17_+_18031304 0.18 ENSDART00000127259
SET domain containing 3
chr2_-_21819421 0.18 ENSDART00000121586
chromodomain helicase DNA binding protein 7
chr11_-_11791718 0.18 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr7_+_38089650 0.18 ENSDART00000052365
CCAAT/enhancer binding protein (C/EBP), gamma
chr15_-_4969525 0.18 ENSDART00000157223
lipoyl(octanoyl) transferase 2
chr2_+_366429 0.18 ENSDART00000111746
si:dkey-33c14.6
chr2_+_8779164 0.18 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr4_-_77125693 0.18 ENSDART00000174256

chr20_+_54304800 0.18 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6

Network of associatons between targets according to the STRING database.

First level regulatory network of en1b_en2a+en2b_gbx1_emx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 1.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 1.0 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.3 1.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 0.8 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.6 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.3 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 2.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 2.2 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.4 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.5 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.4 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.6 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0097065 anterior head development(GO:0097065)
0.1 0.2 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.9 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.4 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 1.6 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0048785 hatching gland development(GO:0048785)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.0 0.4 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957) lateral line ganglion development(GO:0048890)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.3 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.1 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.0 0.1 GO:0010747 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 1.0 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.0 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.0 GO:0045830 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.5 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0060281 regulation of oocyte development(GO:0060281) positive regulation of oocyte development(GO:0060282)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.3 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.0 GO:0051645 Golgi localization(GO:0051645)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.0 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0050796 regulation of insulin secretion(GO:0050796)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097189 apoptotic body(GO:0097189)
0.2 0.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 3.1 GO:0043186 P granule(GO:0043186)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.2 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.2 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 3.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.1 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.0 GO:0072379 ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0030669 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0009374 biotin binding(GO:0009374)
0.2 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 0.5 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 2.1 GO:0032190 acrosin binding(GO:0032190)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 0.5 GO:0008494 translation activator activity(GO:0008494)
0.1 0.6 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.2 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 2.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.1 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 3.9 GO:0042802 identical protein binding(GO:0042802)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 3.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation