Project
PRJNA195909:zebrafish embryo and larva development
Navigation
Downloads
Results for emx2+emx3
Z-value: 2.36
Motif logo
Transcription factors associated with emx2+emx3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| emx2 | dr11_v1_chr13_+_19322686_19322686 | -0.87 | 2.1e-03 | Click! |
| emx3 | dr11_v1_chr14_-_26377044_26377044 | -0.67 | 4.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_10330778 Show fit | 5.68 |
ENSDART00000081465
ENSDART00000136653 ENSDART00000171232 |
coiled-coil domain containing 106b |
|
| chr25_+_22320738 Show fit | 5.28 |
ENSDART00000073566
|
cytochrome P450, family 11, subfamily A, polypeptide 1 |
|
| chr11_-_6452444 Show fit | 5.25 |
ENSDART00000137879
ENSDART00000134957 ENSDART00000004483 |
La ribonucleoprotein domain family, member 6b |
|
| chr17_-_4245902 Show fit | 5.17 |
ENSDART00000151851
|
growth differentiation factor 3 |
|
| chr10_-_34916208 Show fit | 4.91 |
ENSDART00000187371
|
cyclin A1 |
|
| chr1_-_18811517 Show fit | 4.40 |
ENSDART00000142026
|
si:dkey-167i21.2 |
|
| chr2_+_41926707 Show fit | 4.38 |
ENSDART00000023208
|
zgc:110183 |
|
| chr19_-_20403507 Show fit | 4.15 |
ENSDART00000052603
ENSDART00000137590 |
deleted in azoospermia-like |
|
| chr19_-_20403845 Show fit | 4.12 |
ENSDART00000151265
ENSDART00000147911 ENSDART00000151356 |
deleted in azoospermia-like |
|
| chr8_-_23780334 Show fit | 4.00 |
ENSDART00000145179
ENSDART00000145894 |
zgc:195245 |
Network of associatons between targets according to the STRING database.
First level regulatory network of emx2+emx3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 11.0 | GO:0060965 | negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) |
| 0.0 | 10.0 | GO:0006396 | RNA processing(GO:0006396) |
| 1.1 | 5.5 | GO:0038107 | nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) |
| 1.1 | 5.3 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.2 | 3.5 | GO:0071218 | response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218) |
| 0.3 | 3.4 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
| 1.1 | 3.3 | GO:0019852 | L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852) |
| 0.1 | 3.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 3.0 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 3.0 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.9 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 5.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 5.5 | GO:0005769 | early endosome(GO:0005769) |
| 1.6 | 4.9 | GO:0097124 | cyclin A2-CDK2 complex(GO:0097124) |
| 0.0 | 4.9 | GO:0005730 | nucleolus(GO:0005730) |
| 1.1 | 3.4 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.1 | 2.7 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.5 | 2.4 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 2.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 2.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 11.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 9.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 7.6 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 6.1 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 1.8 | 5.3 | GO:0016713 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.1 | 3.2 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 3.2 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 3.2 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 3.1 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 3.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 3.1 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.1 | 2.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 2.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 2.7 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 2.6 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 2.5 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 2.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.8 | PID BARD1 PATHWAY | BARD1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.3 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.3 | 5.0 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.2 | 4.2 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.1 | 3.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.2 | 2.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 2.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 2.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 2.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 2.0 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 2.0 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |