Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for egr1

Z-value: 0.98

Motif logo

Transcription factors associated with egr1

Gene Symbol Gene ID Gene Info
ENSDARG00000037421 early growth response 1
ENSDARG00000115563 early growth response 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr1dr11_v1_chr14_-_21336385_21336385-0.674.7e-02Click!

Activity profile of egr1 motif

Sorted Z-values of egr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_15155684 2.88 ENSDART00000167966
zgc:158852
chr10_-_34002185 2.77 ENSDART00000046599
zygote arrest 1-like
chr19_-_6193448 2.38 ENSDART00000151405
Ets2 repressor factor
chr15_-_17099560 2.14 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr3_-_49504023 2.09 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr19_-_6193067 2.04 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr17_+_46387086 1.68 ENSDART00000157079
si:dkey-206p8.1
chr10_-_32851847 1.64 ENSDART00000134255
tripartite motif containing 37
chr9_+_45227028 1.63 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr22_+_34784075 1.55 ENSDART00000167538
ligand dependent nuclear receptor corepressor
chr17_-_2584423 1.35 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr19_-_2115040 1.31 ENSDART00000020497
sorting nexin 13
chr21_+_19368720 1.30 ENSDART00000187759
ENSDART00000185829
ENSDART00000158471
ENSDART00000168728
betacellulin, epidermal growth factor family member
chr18_+_15106518 1.29 ENSDART00000168639
cryptochrome circadian clock 1ab
chr7_-_20611039 1.25 ENSDART00000170422
si:dkey-19b23.8
chr23_-_22072460 1.24 ENSDART00000132343
polyhomeotic homolog 2a (Drosophila)
chr9_-_54001502 1.21 ENSDART00000085253
midline 1
chr24_+_26379441 1.20 ENSDART00000137786
si:ch211-230g15.5
chr4_-_277081 1.20 ENSDART00000166174
si:ch73-252i11.1
chr2_-_24603325 1.17 ENSDART00000113356
CREB regulated transcription coactivator 1a
chr20_+_27712714 1.16 ENSDART00000008306
zinc finger and BTB domain containing 1
chr25_+_34889061 1.15 ENSDART00000136226
spire-type actin nucleation factor 2
chr23_-_22072716 1.12 ENSDART00000054362
polyhomeotic homolog 2a (Drosophila)
chr2_+_35880600 1.12 ENSDART00000004277
laminin, gamma 1
chr11_+_2855430 1.10 ENSDART00000172837
kinesin family member 21B
chr1_-_17693273 1.09 ENSDART00000146258
cilia and flagella associated protein 97
chr7_+_46019780 1.09 ENSDART00000163991
cyclin E1
chr16_+_13965923 1.09 ENSDART00000103857
zgc:162509
chr15_-_14038227 1.07 ENSDART00000139068
zgc:114130
chr2_+_50062165 1.06 ENSDART00000097939
ENSDART00000138214
zinc finger, CCHC domain containing 2
chr5_+_37720777 1.05 ENSDART00000076083
CDC42 effector protein (Rho GTPase binding) 2
chr1_-_8917902 1.05 ENSDART00000137900
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr9_-_41401564 1.05 ENSDART00000059628
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr13_-_21739142 0.98 ENSDART00000078460
si:dkey-191g9.5
chr2_+_38924975 0.98 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr18_+_3169579 0.96 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr12_+_47448558 0.95 ENSDART00000185689
ENSDART00000105328
formin 2b
chr23_-_31060350 0.94 ENSDART00000145598
ENSDART00000191491
si:ch211-197l9.5
chr23_+_35426404 0.93 ENSDART00000164658
si:ch211-225h24.2
chr8_+_28724692 0.92 ENSDART00000140115
coiled-coil serine-rich protein 1
chr7_+_20563305 0.89 ENSDART00000169661
si:dkey-19b23.10
chr12_-_48943467 0.88 ENSDART00000191829

chr21_+_3941758 0.88 ENSDART00000181345
senataxin
chr25_-_36370292 0.87 ENSDART00000152766
Histone H2B 1/2
chr8_+_2642384 0.86 ENSDART00000143242
nuclear apoptosis inducing factor 1
chr21_-_43398457 0.86 ENSDART00000166530
cyclin I family, member 2
chr17_+_34206167 0.84 ENSDART00000136167
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr23_+_45822935 0.83 ENSDART00000161892
vitamin D receptor a
chr1_+_58977262 0.83 ENSDART00000168832
ERI1 exoribonuclease family member 2
chr20_+_39250673 0.83 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr17_-_25831569 0.83 ENSDART00000148743
hedgehog acyltransferase
chr16_-_13965518 0.81 ENSDART00000138304
si:dkey-85k15.4
chr18_-_50845804 0.80 ENSDART00000158517
si:cabz01113374.3
chr25_+_34888886 0.79 ENSDART00000035245
spire-type actin nucleation factor 2
chr10_-_14920989 0.79 ENSDART00000184617
SMAD family member 2
chr11_-_37880492 0.78 ENSDART00000102868
ethanolamine kinase 2
chr21_-_41369539 0.78 ENSDART00000187546
cytoplasmic polyadenylation element binding protein 4b
chr14_-_4044545 0.78 ENSDART00000169527
sorting nexin 25
chr5_-_67241633 0.77 ENSDART00000114783
CAP-GLY domain containing linker protein 1a
chr14_+_17397534 0.76 ENSDART00000180162
ENSDART00000129838
ring finger protein 212
chr22_-_16275236 0.75 ENSDART00000149051
cell division cycle 14Ab
chr3_+_16722014 0.74 ENSDART00000008711
glycogen synthase 1 (muscle)
chr2_+_23062085 0.74 ENSDART00000153745
casein kinase 1, gamma 2a
chr24_+_19542323 0.73 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr2_+_38271392 0.73 ENSDART00000042100
homeobox and leucine zipper encoding a
chr19_-_25427255 0.72 ENSDART00000036854
glucocorticoid induced 1a
chr21_-_43398122 0.72 ENSDART00000050533
cyclin I family, member 2
chr6_-_7776612 0.72 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr7_+_9326234 0.72 ENSDART00000104536
chondroitin sulfate synthase 1
chr16_+_19029297 0.71 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr5_+_66170479 0.70 ENSDART00000172117
glycine dehydrogenase (decarboxylating)
chr13_-_49666615 0.69 ENSDART00000148083
translocase of outer mitochondrial membrane 20
chr20_-_22778394 0.68 ENSDART00000152645
FIP1 like 1a (S. cerevisiae)
chr13_+_50778187 0.67 ENSDART00000159597
deoxynucleotidyltransferase, terminal
chr17_+_584369 0.64 ENSDART00000165143
chromosome 14 open reading frame 28
chr12_-_37449396 0.64 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr11_+_1565806 0.64 ENSDART00000137479
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr9_+_51784922 0.63 ENSDART00000125850
CD302 molecule
chr2_+_105748 0.63 ENSDART00000169601

chr20_+_27087539 0.62 ENSDART00000062094
transmembrane protein 251
chr1_-_29761086 0.62 ENSDART00000136760
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr7_-_24995631 0.61 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr20_+_28803642 0.61 ENSDART00000188526
farnesyltransferase, CAAX box, beta
chr11_-_2594045 0.60 ENSDART00000114079
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr22_+_10713713 0.60 ENSDART00000122349
hippocampus abundant transcript 1b
chr3_+_51684963 0.59 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
BAI1-associated protein 2a
chr11_+_45461419 0.59 ENSDART00000173424
son of sevenless homolog 1 (Drosophila)
chr7_+_31051603 0.59 ENSDART00000108721
tight junction protein 1a
chr21_-_41369370 0.58 ENSDART00000159290
cytoplasmic polyadenylation element binding protein 4b
chr25_+_29688671 0.58 ENSDART00000073478
bromodomain containing 1b
chr13_-_36761379 0.57 ENSDART00000131534
ENSDART00000029824
mitogen-activated protein kinase kinase kinase kinase 5
chr20_-_46808870 0.56 ENSDART00000190911
estrogen-related receptor gamma b
chr18_+_18612388 0.55 ENSDART00000186455
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr12_+_48511605 0.55 ENSDART00000168389
Rho GTPase activating protein 44
chr3_+_1211242 0.54 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr23_+_44665230 0.52 ENSDART00000144958
calmodulin binding transcription activator 2
chr22_-_193234 0.52 ENSDART00000131067
F-box protein 42
chr7_+_28724919 0.52 ENSDART00000011324
coiled-coil domain containing 102A
chr23_-_16980213 0.52 ENSDART00000046889
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr9_-_105135 0.51 ENSDART00000180126

chr17_+_15983247 0.50 ENSDART00000154275
calmin
chr16_-_26132122 0.49 ENSDART00000157787
lipase, hormone-sensitive b
chr7_-_46019756 0.49 ENSDART00000162583
zgc:162297
chr23_-_31645760 0.48 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr25_-_32888115 0.47 ENSDART00000087586
C2 calcium dependent domain containing 4A
chr3_-_32180796 0.47 ENSDART00000133191
ENSDART00000055308
PIH1 domain containing 1
chr23_-_32100106 0.46 ENSDART00000044658
LETM1 domain containing 1
chr22_-_3564563 0.46 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr13_-_479129 0.46 ENSDART00000159803
ENSDART00000082127
HEAT repeat containing 5B
chr7_+_31051213 0.45 ENSDART00000148347
tight junction protein 1a
chr4_-_5018705 0.45 ENSDART00000154025
striatin interacting protein 2
chr20_+_32523576 0.44 ENSDART00000147319
Scm polycomb group protein like 4
chr12_+_41510492 0.44 ENSDART00000170976
ENSDART00000176164
kinesin family member 5B, b
chr12_+_34273240 0.44 ENSDART00000037904
suppressor of cytokine signaling 3b
chr3_-_42016693 0.44 ENSDART00000184741
tweety family member 3a
chr25_+_36315127 0.42 ENSDART00000191984
zgc:165555
chr24_-_42072886 0.42 ENSDART00000171389

chr3_+_1107102 0.42 ENSDART00000092690
sterol regulatory element binding transcription factor 2
chr20_+_28803977 0.42 ENSDART00000153351
ENSDART00000038149
farnesyltransferase, CAAX box, beta
chr4_+_77948517 0.40 ENSDART00000149305
protein kinase C and casein kinase substrate in neurons 2
chr6_+_2271559 0.40 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr7_-_52498175 0.38 ENSDART00000129769
cingulin-like 1
chr20_+_46699021 0.38 ENSDART00000167398
ENSDART00000029894
WD repeat domain 26b
chr11_-_42418374 0.37 ENSDART00000160704
sarcolemma associated protein a
chr2_+_23701613 0.36 ENSDART00000047073
oxidative stress responsive 1a
chr21_+_27513859 0.36 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr21_+_103194 0.36 ENSDART00000162755
zyg-11 related, cell cycle regulator
chr5_+_72377851 0.36 ENSDART00000160479
lectin, mannose-binding 2-like a
chr1_+_49435017 0.36 ENSDART00000124833
programmed cell death 11
chr3_-_5228137 0.36 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr7_+_5968225 0.35 ENSDART00000083397
zgc:165555
chr2_+_20793982 0.35 ENSDART00000014785
proteoglycan 4a
chr1_+_59146298 0.35 ENSDART00000191885
ENSDART00000152747
G protein-coupled receptor 108
chr19_+_935565 0.34 ENSDART00000113368
ring finger protein 5
chr1_-_10473630 0.33 ENSDART00000040116
trinucleotide repeat containing 5
chr4_-_5019113 0.33 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr20_+_38458084 0.33 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr10_+_11282883 0.32 ENSDART00000135355
si:ch211-126i22.5
chr1_+_12295142 0.32 ENSDART00000158595
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_+_45436703 0.32 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr17_+_15983557 0.32 ENSDART00000190806
calmin
chr25_-_6389713 0.31 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr23_-_270847 0.31 ENSDART00000191867
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr10_+_8554929 0.31 ENSDART00000190849
TBC1 domain family, member 10Ab
chr14_-_7245971 0.30 ENSDART00000108796
storkhead box 2b
chr6_+_42338309 0.30 ENSDART00000015277
glutathione peroxidase 1b
chr7_-_66126628 0.30 ENSDART00000184492
BTB (POZ) domain containing 10b
chr19_+_2619444 0.29 ENSDART00000169483
family with sequence similarity 126, member A
chr10_-_35030673 0.29 ENSDART00000135338
SPT20 homolog, SAGA complex component
chr1_+_176583 0.29 ENSDART00000168760
ENSDART00000160425
lysosomal associated membrane protein 1
chr12_-_850457 0.29 ENSDART00000022688
transducer of ERBB2, 1b
chr5_-_2689753 0.28 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr2_-_44344321 0.28 ENSDART00000084174
ligase I, DNA, ATP-dependent
chr15_+_17406920 0.27 ENSDART00000081059
ribosomal protein S6 kinase b, polypeptide 1b
chr7_+_41340520 0.26 ENSDART00000005127
GRB2 associated, regulator of MAPK1
chr25_-_36310561 0.26 ENSDART00000181152
zgc:165555
chr14_+_164556 0.25 ENSDART00000185606
WD repeat domain 1
chr21_+_26620867 0.25 ENSDART00000176008
estrogen-related receptor alpha
chr19_-_81477 0.25 ENSDART00000159815
heterogeneous nuclear ribonucleoprotein R
chr21_-_24865217 0.25 ENSDART00000101136
immunoglobulin superfamily, member 9Bb
chr5_-_21524251 0.24 ENSDART00000176793
ENSDART00000040184
teneurin transmembrane protein 1
chr17_+_8323348 0.24 ENSDART00000169900
CDC42 binding protein kinase alpha (DMPK-like) a
chr2_+_16710889 0.23 ENSDART00000017852
UBX domain protein 7
chr6_-_25181012 0.23 ENSDART00000161585
leucine rich repeat containing 8 VRAC subunit Db
chr2_-_54639964 0.23 ENSDART00000100103
acyl-CoA synthetase short chain family member 2 like
chr8_+_20438884 0.22 ENSDART00000016422
ENSDART00000133794
MAP kinase interacting serine/threonine kinase 2b
chr11_+_25296366 0.22 ENSDART00000065949
DNA topoisomerase I, like
chr21_-_33126697 0.22 ENSDART00000189293
ENSDART00000084559

chr14_+_48960078 0.21 ENSDART00000165514
macrophage migration inhibitory factor
chr6_+_14301214 0.21 ENSDART00000129491
transmembrane protein 182b
chr7_-_26603743 0.20 ENSDART00000099003
phospholipid scramblase 3b
chr19_+_2602903 0.19 ENSDART00000033132
family with sequence similarity 126, member A
chr1_-_52505279 0.19 ENSDART00000052907
aspartoacylase (aminocyclase) 3, tandem duplicate 1
chr6_-_13498745 0.19 ENSDART00000027684
ENSDART00000189438
myosin light chain kinase b
chr2_-_50272077 0.19 ENSDART00000127623
cullin 1a
chr17_+_20639180 0.19 ENSDART00000063624
neuropeptide Y receptor Y4
chr22_+_1751640 0.19 ENSDART00000162093
zinc finger protein 1169
chr25_-_13050959 0.19 ENSDART00000169041
chemokine (C-C motif) ligand 35, duplicate 1
chr7_-_12596727 0.19 ENSDART00000186413
ADAMTS-like 3
chr11_+_45461853 0.19 ENSDART00000173409
son of sevenless homolog 1 (Drosophila)
chr11_-_31146808 0.18 ENSDART00000172781
si:cabz01069582.1
chr1_-_7917062 0.18 ENSDART00000177068
monocyte to macrophage differentiation-associated 2b
chr24_+_32472155 0.18 ENSDART00000098859
neuronal differentiation 6a
chr17_-_14726824 0.18 ENSDART00000162947
si:ch73-305o9.3
chr22_+_15979430 0.18 ENSDART00000189703
ENSDART00000192674
ring finger and CCCH-type domains 1a
chr2_+_59046036 0.17 ENSDART00000158860
serine/threonine kinase 11
chr8_-_15292197 0.17 ENSDART00000140867
spermatogenesis associated 6
chr6_-_57408576 0.17 ENSDART00000163930
zinc finger, NFX1-type containing 1
chr25_-_7999756 0.17 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr20_-_26624042 0.17 ENSDART00000077962
exocyst complex component 2
chr22_-_6499055 0.17 ENSDART00000142235
ENSDART00000183588
si:dkey-19a16.7
chr14_-_15155384 0.16 ENSDART00000172666
UV-stimulated scaffold protein A
chr17_+_53435279 0.16 ENSDART00000126630
connexin 52.9
chr19_+_7154500 0.15 ENSDART00000035967
ENSDART00000160894
bromodomain containing 2a
chr19_-_3303995 0.14 ENSDART00000105150
si:ch211-133n4.9
chr22_-_10605045 0.14 ENSDART00000184812
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr6_+_34511886 0.14 ENSDART00000179450
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_+_65492183 0.14 ENSDART00000162804
si:dkey-21e5.1
chr16_-_8520474 0.13 ENSDART00000137365
growth factor receptor-bound protein 10b
chr6_+_13206516 0.13 ENSDART00000036927
NADH dehydrogenase (ubiquinone) Fe-S protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of egr1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.6 1.7 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.1 GO:0010657 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3 1.0 GO:0018343 protein farnesylation(GO:0018343)
0.2 1.9 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 1.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 2.1 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 0.8 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 0.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 1.7 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.0 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.7 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 1.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.8 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.7 GO:0060876 semicircular canal formation(GO:0060876)
0.1 1.0 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.7 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.6 GO:0032475 otolith formation(GO:0032475)
0.1 1.4 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.7 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.8 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.0 2.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.0 0.6 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.4 GO:0044857 membrane raft assembly(GO:0001765) membrane raft organization(GO:0031579) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 1.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.8 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.7 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 7.3 GO:0045892 negative regulation of transcription, DNA-templated(GO:0045892)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0060349 bone morphogenesis(GO:0060349)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 1.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.6 GO:0016234 inclusion body(GO:0016234)
0.2 0.7 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0005795 Golgi stack(GO:0005795)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.7 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.4 1.7 GO:0071253 connexin binding(GO:0071253)
0.4 2.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 0.9 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.3 1.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.6 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 0.7 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0016594 glycine binding(GO:0016594)
0.1 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 4.0 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.8 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 3.1 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.6 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism