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PRJNA195909:zebrafish embryo and larva development

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Results for dlx5a

Z-value: 0.40

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Transcription factors associated with dlx5a

Gene Symbol Gene ID Gene Info
ENSDARG00000042296 distal-less homeobox 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx5adr11_v1_chr19_-_41472228_41472228-0.827.4e-03Click!

Activity profile of dlx5a motif

Sorted Z-values of dlx5a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_19596214 0.89 ENSDART00000183110

chr2_+_6253246 0.75 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr4_+_306036 0.55 ENSDART00000103659
mesogenin 1
chr24_+_1023839 0.52 ENSDART00000082526
zgc:111976
chr11_-_44801968 0.52 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr10_-_35149513 0.43 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr6_-_43283122 0.40 ENSDART00000186022
FERM domain containing 4Ba
chr13_-_33227411 0.30 ENSDART00000057386
golgin A5
chr17_+_43867889 0.30 ENSDART00000132673
ENSDART00000167214
zgc:66313
chr23_-_31913069 0.30 ENSDART00000135526
mitochondrial fission regulator 2
chr17_+_43863708 0.30 ENSDART00000133874
ENSDART00000140316
ENSDART00000142929
ENSDART00000148090
zgc:66313
chr16_-_42056137 0.29 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr20_-_14114078 0.29 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr2_-_21819421 0.28 ENSDART00000121586
chromodomain helicase DNA binding protein 7
chr14_+_11290828 0.28 ENSDART00000184078
ring finger protein, LIM domain interacting
chr20_+_46513651 0.24 ENSDART00000152977
zinc finger CCCH-type containing 14
chr11_+_31864921 0.24 ENSDART00000180252
diaphanous-related formin 3
chr6_+_23026714 0.23 ENSDART00000124948
signal recognition particle 68
chr8_-_39822917 0.22 ENSDART00000067843
zgc:162025
chr2_-_2451181 0.22 ENSDART00000101033
parathyroid hormone 1 receptor a
chr16_+_35661771 0.22 ENSDART00000161393
MAP7 domain containing 1a
chr3_-_23643751 0.21 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr17_+_49500820 0.21 ENSDART00000170306
apoptosis resistant E3 ubiquitin protein ligase 1
chr23_-_31913231 0.21 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr7_-_51368681 0.20 ENSDART00000146385
Rho GTPase activating protein 36
chr22_-_11517377 0.19 ENSDART00000193885
solute carrier family 26 (anion exchanger), member 11
chr17_-_43863700 0.19 ENSDART00000157530
AHA1, activator of heat shock protein ATPase homolog 1b
chr15_+_29140126 0.19 ENSDART00000060034
zgc:113149
chr6_-_40922971 0.18 ENSDART00000155363
SFI1 centrin binding protein
chr16_+_35661331 0.17 ENSDART00000161725
MAP7 domain containing 1a
chr16_+_42471455 0.17 ENSDART00000166640
si:ch211-215k15.5
chr20_+_14114258 0.17 ENSDART00000044937
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr19_-_27336092 0.16 ENSDART00000176885
general transcription factor IIH, polypeptide 4
chr7_-_12464412 0.15 ENSDART00000178723
ADAMTS-like 3
chr3_+_32832538 0.14 ENSDART00000139410
CD2 (cytoplasmic tail) binding protein 2
chr23_+_34990693 0.14 ENSDART00000013449
si:ch211-236h17.3
chr1_+_40199074 0.13 ENSDART00000179679
ENSDART00000136849
si:ch211-113e8.5
chr16_+_28994709 0.13 ENSDART00000088023
gon-4-like (C. elegans)
chr1_-_53277413 0.13 ENSDART00000150579
zinc finger protein 330
chr10_+_20392083 0.13 ENSDART00000166867
R3H domain and coiled-coil containing 1
chr10_-_13343831 0.12 ENSDART00000135941
interleukin 11 receptor, alpha
chr3_-_23512285 0.12 ENSDART00000159151

chr12_+_1469090 0.11 ENSDART00000183637
ubiquitin specific peptidase 22
chr12_-_14211293 0.11 ENSDART00000158399
AVL9 homolog (S. cerevisiase)
chr19_+_20793388 0.11 ENSDART00000142463
thioredoxin-like 4A
chr16_+_45425181 0.10 ENSDART00000168591
PHD finger protein 1
chr1_-_13989643 0.10 ENSDART00000191046
E74-like factor 2b (ets domain transcription factor)
chr19_+_20793237 0.10 ENSDART00000014774
thioredoxin-like 4A
chr25_-_7705487 0.10 ENSDART00000128099
PR domain containing 11
chr8_-_537716 0.09 ENSDART00000051777
zgc:101664
chr20_-_8094718 0.09 ENSDART00000122902
si:ch211-232i5.3
chr7_+_69019851 0.09 ENSDART00000162891

chr9_-_49964810 0.09 ENSDART00000167098
sodium channel, voltage-gated, type I, alpha
chr4_-_63848305 0.09 ENSDART00000097308

chr10_+_2529037 0.09 ENSDART00000123467
zmp:0000001301
chr17_+_25187226 0.08 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr24_+_7336411 0.08 ENSDART00000191170
lysine (K)-specific methyltransferase 2Ca
chr7_-_69647988 0.08 ENSDART00000169943

chr24_-_39637418 0.07 ENSDART00000142522
family with sequence similarity 234, member A
chr18_+_50461981 0.07 ENSDART00000158761

chr14_-_14705750 0.07 ENSDART00000168092
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr23_+_44374041 0.06 ENSDART00000136056
eph receptor B4b
chr20_+_35484070 0.05 ENSDART00000026234
ENSDART00000141675
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr16_-_35329803 0.05 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
protein tyrosine phosphatase, receptor type, U, b
chr24_-_32582378 0.05 ENSDART00000066590
retinol dehydrogenase 12, like
chr8_-_50888806 0.04 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr16_+_45424907 0.04 ENSDART00000134471
PHD finger protein 1
chr23_+_31912882 0.04 ENSDART00000140505
armadillo repeat containing 1, like
chr4_-_5795309 0.04 ENSDART00000039987
phosphoglucomutase 3
chr4_-_76184243 0.04 ENSDART00000180937
si:ch211-106j21.4
chr20_+_39457598 0.04 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr2_+_38370535 0.03 ENSDART00000179614
proteasome subunit beta 11a
chr9_+_13229585 0.03 ENSDART00000154879
ENSDART00000141705
calcium responsive transcription factor
chr13_+_24829996 0.03 ENSDART00000147194
si:ch211-223p8.8
chr20_-_3004126 0.03 ENSDART00000064390
peptidylprolyl isomerase (cyclophilin)-like 4
chr21_+_39948300 0.02 ENSDART00000137740
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr1_-_17715493 0.02 ENSDART00000133027
si:dkey-256e7.8
chr23_+_33963619 0.02 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr16_-_30934319 0.02 ENSDART00000109940
G protein-coupled receptor 20
chr19_+_5480327 0.01 ENSDART00000148794
junction plakoglobin b
chr16_-_31525290 0.00 ENSDART00000109996
WNT1 inducible signaling pathway protein 1b
chr5_+_66433287 0.00 ENSDART00000170757
kinetochore associated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0097065 anterior head development(GO:0097065)
0.0 0.1 GO:0045830 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0048798 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)