Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Z-value: 0.93

Motif logo

Transcription factors associated with dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Gene Symbol Gene ID Gene Info
ENSDARG00000017174 distal-less homeobox 2b
ENSDARG00000079964 distal-less homeobox 2a
ENSDARG00000116017 distal-less homeobox 2b
ENSDARG00000011956 distal-less homeobox 4a
ENSDARG00000042291 distal-less homeobox 6a
ENSDARG00000071560 distal-less homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx2bdr11_v1_chr1_-_30979707_309797070.781.3e-02Click!
dlx6adr11_v1_chr19_+_41464870_414648700.732.5e-02Click!
dlx2adr11_v1_chr9_-_3400727_34007290.541.3e-01Click!
dlx4bdr11_v1_chr12_-_5728755_57287550.481.9e-01Click!
dlx4adr11_v1_chr3_+_34670076_346700760.472.0e-01Click!

Activity profile of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Sorted Z-values of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_25449681 2.24 ENSDART00000101328
atonal bHLH transcription factor 7
chr11_+_30244356 1.57 ENSDART00000036050
ENSDART00000150080
retinoschisin 1a
chr8_+_21353878 1.56 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr25_+_29160102 1.52 ENSDART00000162854
pyruvate kinase M1/2b
chr21_+_28478663 1.29 ENSDART00000077887
ENSDART00000134150
solute carrier family 22 (organic anion transporter), member 6, like
chr6_+_52804267 1.25 ENSDART00000065681
matrilin 4
chr12_+_24342303 1.12 ENSDART00000111239
neurexin 1a
chr24_+_38306010 1.10 ENSDART00000143184
myosin binding protein C, fast type b
chr16_+_20910186 1.01 ENSDART00000046766
homeobox A10b
chr20_-_9462433 0.99 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr16_+_31804590 0.97 ENSDART00000167321
wingless-type MMTV integration site family, member 4b
chr16_+_5774977 0.96 ENSDART00000134202
cholecystokinin a
chr23_+_28731379 0.91 ENSDART00000047378
cortistatin
chr6_-_54826061 0.89 ENSDART00000149982
troponin I type 1b (skeletal, slow)
chr13_-_31435137 0.84 ENSDART00000057441
reticulon 1a
chr4_+_12615836 0.82 ENSDART00000003583
LIM domain only 3
chr17_-_31659670 0.82 ENSDART00000030448
visual system homeobox 2
chr22_+_16535575 0.81 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr13_-_50108337 0.77 ENSDART00000133308
nidogen 1a
chr7_+_30787903 0.76 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr4_-_9891874 0.75 ENSDART00000067193
adrenomedullin 2a
chr21_+_27416284 0.75 ENSDART00000077593
ENSDART00000108763
complement factor B
chr15_-_6247775 0.72 ENSDART00000148350
Down syndrome cell adhesion molecule b
chr15_-_21877726 0.71 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr1_+_52929185 0.71 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr19_+_10339538 0.69 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr5_-_14326959 0.61 ENSDART00000137355
tet methylcytosine dioxygenase 3
chr15_-_23376541 0.60 ENSDART00000078570
C1q and TNF related 5
chr20_+_34933183 0.60 ENSDART00000062738
synaptosomal-associated protein, 25a
chr20_-_32270866 0.60 ENSDART00000153140
armadillo repeat containing 2
chr13_+_38430466 0.59 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr13_-_40401870 0.58 ENSDART00000128951
NK3 homeobox 3
chr19_+_19786117 0.57 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr16_+_20161805 0.57 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr24_-_24849091 0.55 ENSDART00000133649
ENSDART00000038290
corticotropin releasing hormone b
chr1_-_50859053 0.54 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr12_+_22580579 0.53 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr21_+_28958471 0.53 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_-_29119362 0.53 ENSDART00000104204
forkhead box G1a
chr11_-_6974022 0.53 ENSDART00000172851
si:ch211-43f4.1
chr17_+_23298928 0.53 ENSDART00000153652
zgc:165461
chr15_-_22074315 0.52 ENSDART00000149830
dopamine receptor D2a
chr2_+_50608099 0.52 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr3_-_46817499 0.51 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr2_+_37227011 0.51 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr16_-_17197546 0.51 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr22_+_20427170 0.50 ENSDART00000136744
forkhead box Q2
chr9_+_24008879 0.50 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
melanophilin b
chr1_+_16397063 0.50 ENSDART00000159794
mitochondrial calcium uptake family, member 3a
chr17_-_20717845 0.50 ENSDART00000150037
ankyrin 3b
chr22_+_5176255 0.50 ENSDART00000092647
ceramide synthase 1
chr6_+_39232245 0.49 ENSDART00000187351
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr23_-_38497705 0.48 ENSDART00000109493
teashirt zinc finger homeobox 2
chr22_-_10502780 0.47 ENSDART00000136961
extracellular matrix protein 2, female organ and adipocyte specific
chr1_-_43905252 0.47 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr20_-_28800999 0.47 ENSDART00000049462
RAB15, member RAS oncogene family
chr15_+_9053059 0.44 ENSDART00000012039
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr1_+_16396870 0.44 ENSDART00000189245
ENSDART00000113266
mitochondrial calcium uptake family, member 3a
chr14_-_30587814 0.44 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr22_+_5176693 0.43 ENSDART00000160927
ceramide synthase 1
chr7_-_28148310 0.43 ENSDART00000044208
LIM domain only 1
chr2_-_33645411 0.42 ENSDART00000114663
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr4_+_12612723 0.42 ENSDART00000133767
LIM domain only 3
chr3_-_32337653 0.42 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr5_-_23117078 0.41 ENSDART00000051529
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr4_-_15420452 0.41 ENSDART00000016230
plexin A4
chr10_+_3049636 0.40 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
Ras protein-specific guanine nucleotide-releasing factor 2a
chr16_-_13921589 0.40 ENSDART00000023543
recoverin 2
chr6_+_23887314 0.40 ENSDART00000163188
zinc finger protein 648
chr12_+_20352400 0.39 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr3_+_33341640 0.39 ENSDART00000186352
peptide YYa
chr4_+_11384891 0.37 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
piccolo presynaptic cytomatrix protein a
chr18_-_1185772 0.37 ENSDART00000143245
neuroplastin b
chr4_+_12612145 0.37 ENSDART00000181201
LIM domain only 3
chr22_-_11136625 0.36 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr1_-_44701313 0.35 ENSDART00000193926
si:dkey-28b4.8
chr16_+_17389116 0.34 ENSDART00000103750
ENSDART00000173448
family with sequence similarity 131, member Bb
chr6_-_41229787 0.34 ENSDART00000065013
synaptoporin
chr14_-_17622080 0.34 ENSDART00000112149
si:ch211-159i8.4
chr2_-_23004286 0.33 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr17_-_12389259 0.33 ENSDART00000185724
synaptosomal-associated protein, 25b
chr4_+_26629368 0.33 ENSDART00000183575
IQ motif and Sec7 domain 3a
chr17_-_16965809 0.32 ENSDART00000153697
neurexin 3a
chr20_+_28861435 0.32 ENSDART00000142678
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr20_-_29420713 0.31 ENSDART00000147464
ryanodine receptor 3
chr8_-_25034411 0.31 ENSDART00000135973
nuclear transcription factor Y, alpha, like
chr10_-_34871737 0.31 ENSDART00000138755
doublecortin-like kinase 1a
chr20_+_30445971 0.31 ENSDART00000153150
myelin transcription factor 1-like, a
chr20_-_46362606 0.31 ENSDART00000153087
BCL2 modifying factor 2
chr17_-_44247707 0.30 ENSDART00000126097
orthodenticle homeobox 2b
chr5_+_19314574 0.29 ENSDART00000133247
RUN and SH3 domain containing 2
chr25_-_18913336 0.28 ENSDART00000171010
parietopsin
chr10_+_36178713 0.28 ENSDART00000140816
odorant receptor, family D, subfamily 108, member 3
chr20_-_40755614 0.28 ENSDART00000061247
connexin 32.3
chr2_+_21229909 0.27 ENSDART00000046127
vasoactive intestinal peptide receptor 1a
chr18_-_48550426 0.27 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr19_-_5103141 0.27 ENSDART00000150952
triosephosphate isomerase 1a
chr10_+_29698467 0.27 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr20_-_38617766 0.26 ENSDART00000050474
solute carrier family 30 (zinc transporter), member 2
chr10_-_35236949 0.26 ENSDART00000145804
yippee-like 2a
chr20_+_28861629 0.25 ENSDART00000187274
ENSDART00000047826
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr6_-_6487876 0.25 ENSDART00000137642
centrosomal protein 170Ab
chr23_-_29824146 0.25 ENSDART00000020616
zgc:194189
chr19_-_7358184 0.24 ENSDART00000092379
oxidation resistance 1b
chr21_+_34088377 0.24 ENSDART00000170070
myotubularin related protein 1b
chr15_-_2184638 0.24 ENSDART00000135460
short stature homeobox 2
chr19_-_19871211 0.24 ENSDART00000170980
even-skipped homeobox 1
chr15_+_31806303 0.24 ENSDART00000155902
furry homolog a (Drosophila)
chr6_-_14292307 0.23 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr19_-_205104 0.22 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr20_-_10120442 0.22 ENSDART00000144970
Meis homeobox 2b
chr21_+_29077509 0.21 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr20_-_22476255 0.21 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr14_-_3381303 0.21 ENSDART00000171601
im:7150988
chr19_-_42607451 0.21 ENSDART00000004392
FK506 binding protein 9
chr21_+_34088110 0.21 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr10_-_1788376 0.20 ENSDART00000123842
erythrocyte membrane protein band 4.1 like 4A
chr4_+_16885854 0.20 ENSDART00000017726
ethanolamine kinase 1
chr19_+_22062202 0.19 ENSDART00000100181
spalt-like transcription factor 3b
chr21_-_17296789 0.19 ENSDART00000192180
growth factor independent 1B transcription repressor
chr8_-_38477817 0.18 ENSDART00000075989
inositol polyphosphate-5-phosphatase L
chr16_-_13623928 0.18 ENSDART00000164344
si:dkeyp-69b9.6
chr7_+_27603211 0.18 ENSDART00000148782
cytochrome P450, family 2, subfamily R, polypeptide 1
chr11_+_38280454 0.18 ENSDART00000171496
si:dkey-166c18.1
chr13_-_36911118 0.18 ENSDART00000048739
tripartite motif containing 9
chr20_-_27711970 0.18 ENSDART00000139637
zinc finger and BTB domain containing 25
chr16_+_13818500 0.18 ENSDART00000135245
folliculin
chr21_-_40676224 0.17 ENSDART00000162623
aristaless related homeobox b
chr2_-_17235891 0.17 ENSDART00000144251
artemin b
chr4_+_7391110 0.17 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr3_-_34296361 0.17 ENSDART00000181485
ENSDART00000113726
trinucleotide repeat containing 6C1
chr13_-_44630111 0.17 ENSDART00000110092
MAM domain containing glycosylphosphatidylinositol anchor 1
chr7_+_2236317 0.17 ENSDART00000075859
zgc:172065
chr20_+_4060839 0.17 ENSDART00000178565
tripartite motif containing 67
chr12_+_48803098 0.16 ENSDART00000074768
peptidylprolyl isomerase Fb
chr15_+_15856178 0.16 ENSDART00000080338
dual specificity phosphatase 14
chr15_+_36309070 0.16 ENSDART00000157034
geminin coiled-coil domain containing
chr14_+_36220479 0.16 ENSDART00000148319
paired-like homeodomain 2
chr16_+_23087326 0.16 ENSDART00000167518
ENSDART00000161087
ephrin-A3b
chr11_-_37509001 0.16 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr13_+_25720969 0.16 ENSDART00000046050
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr22_+_35068046 0.16 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
chr11_-_39105253 0.16 ENSDART00000102827
prolyl 3-hydroxylase 1
chr17_+_21295132 0.16 ENSDART00000103845
enolase family member 4
chr22_-_20166660 0.15 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr21_-_5856050 0.15 ENSDART00000115367

chr18_-_19456269 0.14 ENSDART00000060363
ribosomal protein L4
chr1_-_22512063 0.14 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr1_+_11977426 0.13 ENSDART00000103399
tetraspanin 5b
chr3_+_34919810 0.13 ENSDART00000055264
carbonic anhydrase Xb
chr1_-_44704261 0.13 ENSDART00000133210
si:dkey-28b4.8
chr12_-_35830625 0.13 ENSDART00000180028

chrM_+_9052 0.13 ENSDART00000093612
ATP synthase 6, mitochondrial
chr22_-_23000815 0.13 ENSDART00000137111
protein tyrosine phosphatase, receptor type, C
chr25_+_18965430 0.12 ENSDART00000169742
thymine DNA glycosylase, tandem duplicate 1
chr1_-_5455498 0.12 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr2_-_16380283 0.12 ENSDART00000149992
si:dkey-231j24.3
chr9_-_51436377 0.12 ENSDART00000006612
T-box, brain, 1b
chr1_+_34696503 0.12 ENSDART00000186106

chr8_-_46894362 0.12 ENSDART00000111124
acyl-CoA thioesterase 7
chr10_+_11282883 0.11 ENSDART00000135355
si:ch211-126i22.5
chr14_+_30568961 0.11 ENSDART00000184303
mitochondrial ribosomal protein L11
chr23_+_20563779 0.11 ENSDART00000146008
CaM kinase-like vesicle-associated, like
chr21_-_42100471 0.10 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr9_-_21918963 0.10 ENSDART00000090782
LIM domain 7a
chr10_-_24689280 0.09 ENSDART00000191476
si:ch211-287a12.9
chr15_-_38154616 0.09 ENSDART00000099392
immunity-related GTPase family, q2
chr8_+_28259347 0.09 ENSDART00000110857
family with sequence similarity 212, member B
chr12_+_22258962 0.09 ENSDART00000131175
wingless-type MMTV integration site family, member 3
chr1_-_21723329 0.08 ENSDART00000137138
si:ch211-134c9.2
chr11_+_30057762 0.08 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr6_+_36807861 0.08 ENSDART00000161708
si:ch73-29l19.1
chr17_-_19963718 0.08 ENSDART00000154251
cholinergic receptor, muscarinic 3a
chr1_+_45323400 0.08 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr6_+_52877147 0.08 ENSDART00000174370
odorant receptor, family H, subfamily 137, member 8
chr22_+_28320792 0.07 ENSDART00000160562
ENSDART00000164138
interphotoreceptor matrix proteoglycan 2b
interphotoreceptor matrix proteoglycan 2b
chr5_+_66433287 0.07 ENSDART00000170757
kinetochore associated 1
chr22_+_18477934 0.07 ENSDART00000132684
cartilage intermediate layer protein 2
chr16_-_12953739 0.07 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr18_+_15644559 0.07 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr16_+_54263921 0.07 ENSDART00000002856
dopamine receptor D2 like
chr1_-_54765262 0.06 ENSDART00000150362
si:ch211-197k17.3
chr14_+_30762131 0.06 ENSDART00000145039
si:ch211-145o7.3
chr5_+_20147830 0.06 ENSDART00000098727
SV2 related protein a
chr23_-_10831995 0.06 ENSDART00000142533
PDZ domain containing RING finger 3a
chr19_+_46158078 0.06 ENSDART00000183933
ENSDART00000164055
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr10_+_43039947 0.06 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr8_-_30204650 0.06 ENSDART00000133209
zgc:162939
chr5_-_30481263 0.06 ENSDART00000086734
pleckstrin homology-like domain, family B, member 1a
chr5_+_37032038 0.05 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_+_56755536 0.05 ENSDART00000157727

chr10_+_16584382 0.05 ENSDART00000112039

chr23_-_4966821 0.05 ENSDART00000147122
ENSDART00000145760
nerve growth factor a (beta polypeptide)
chr18_+_9362455 0.05 ENSDART00000187025
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr9_-_24244383 0.04 ENSDART00000182407
caveolae associated protein 2a
chr13_+_21768447 0.04 ENSDART00000100941
coiled-coil-helix-coiled-coil-helix domain containing 1
chr11_+_35050253 0.04 ENSDART00000124800
family with sequence similarity 212, member Aa
chr9_-_20372977 0.04 ENSDART00000113418
immunoglobulin superfamily, member 3
chr16_-_19890303 0.04 ENSDART00000147161
ENSDART00000079159
histone deacetylase 9b
chr21_-_15046065 0.04 ENSDART00000178507
matrix metallopeptidase 17a

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 0.6 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.7 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.6 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.6 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.3 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.5 GO:0043584 nose development(GO:0043584)
0.1 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.7 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.6 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.7 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 1.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 2.2 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0061072 iris morphogenesis(GO:0061072)
0.0 1.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.2 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.0 1.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.0 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 1.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.4 GO:0007631 feeding behavior(GO:0007631)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0006956 complement activation(GO:0006956)
0.0 0.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.9 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 1.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.5 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.4 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 0.3 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE