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PRJNA195909:zebrafish embryo and larva development
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Results for cebpb
Z-value: 1.96
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Transcription factors associated with cebpb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| cebpb | dr11_v1_chr8_-_28449782_28449782 | 0.26 | 5.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_50147948 Show fit | 4.61 |
ENSDART00000149010
|
haptoglobin |
|
| chr14_+_36885524 Show fit | 4.05 |
ENSDART00000032547
|
leukocyte cell-derived chemotaxin 2 like |
|
| chr16_-_21785261 Show fit | 3.84 |
ENSDART00000078858
|
si:ch73-86n18.1 |
|
| chr5_-_63509581 Show fit | 3.71 |
ENSDART00000097325
|
complement component 5 |
|
| chr5_-_30615901 Show fit | 3.56 |
ENSDART00000147769
|
si:ch211-117m20.5 |
|
| chr12_-_5120175 Show fit | 3.52 |
ENSDART00000160729
|
retinol binding protein 4, plasma |
|
| chr3_+_30921246 Show fit | 3.09 |
ENSDART00000076850
|
claudin i |
|
| chr15_+_32711663 Show fit | 3.09 |
ENSDART00000157854
ENSDART00000167515 |
periostin, osteoblast specific factor b |
|
| chr9_+_3388099 Show fit | 3.07 |
ENSDART00000019910
|
distal-less homeobox 1a |
|
| chr14_-_12071679 Show fit | 2.80 |
ENSDART00000165581
|
thymosin beta 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of cebpb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.0 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.5 | 4.6 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.5 | 3.6 | GO:0006211 | 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857) |
| 0.5 | 3.5 | GO:0046864 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) |
| 0.0 | 3.2 | GO:0009880 | embryonic pattern specification(GO:0009880) |
| 0.5 | 3.1 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.2 | 3.1 | GO:0016203 | muscle attachment(GO:0016203) |
| 0.1 | 3.1 | GO:0043297 | apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830) |
| 0.6 | 2.9 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.2 | 2.9 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 37.3 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 3.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 2.8 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.2 | 2.3 | GO:0090533 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.2 | 2.3 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 2.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.7 | 2.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 2.0 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.2 | 1.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 1.7 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.0 | 5.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 4.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 4.7 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 4.7 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.2 | 4.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 3.8 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.5 | 3.6 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.5 | 3.5 | GO:0034632 | retinol transporter activity(GO:0034632) |
| 0.1 | 3.5 | GO:0003823 | antigen binding(GO:0003823) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 2.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 2.3 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.2 | 2.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 2.0 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 2.0 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 1.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 1.6 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 1.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 1.4 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.3 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 2.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 2.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.1 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 2.1 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 2.0 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.2 | 2.0 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 1.9 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 1.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.7 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |