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PRJNA195909:zebrafish embryo and larva development
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Results for cebpa
Z-value: 1.25
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Transcription factors associated with cebpa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| cebpa | dr11_v1_chr7_-_38087865_38087865 | 0.40 | 2.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_50147948 Show fit | 3.06 |
ENSDART00000149010
|
haptoglobin |
|
| chr14_+_36885524 Show fit | 2.28 |
ENSDART00000032547
|
leukocyte cell-derived chemotaxin 2 like |
|
| chr12_+_15008582 Show fit | 1.87 |
ENSDART00000003847
|
myosin light chain, phosphorylatable, fast skeletal muscle b |
|
| chr12_+_15002757 Show fit | 1.82 |
ENSDART00000135036
|
myosin light chain, phosphorylatable, fast skeletal muscle b |
|
| chr16_-_21785261 Show fit | 1.62 |
ENSDART00000078858
|
si:ch73-86n18.1 |
|
| chr2_-_40199780 Show fit | 1.39 |
ENSDART00000113901
|
chemokine (C-C motif) ligand 34a, duplicate 4 |
|
| chr14_+_46313396 Show fit | 1.27 |
ENSDART00000047525
|
crystallin, beta A1, like 1 |
|
| chr6_-_24103666 Show fit | 1.26 |
ENSDART00000164915
|
scinderin like a |
|
| chr5_-_30615901 Show fit | 1.25 |
ENSDART00000147769
|
si:ch211-117m20.5 |
|
| chr15_+_32711663 Show fit | 1.21 |
ENSDART00000157854
ENSDART00000167515 |
periostin, osteoblast specific factor b |
Network of associatons between targets according to the STRING database.
First level regulatory network of cebpa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.8 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 1.9 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.1 | 1.5 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 0.0 | 1.5 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 1.4 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 1.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 1.3 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.2 | 1.2 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.1 | 1.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 1.2 | GO:0042594 | response to starvation(GO:0042594) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 19.4 | GO:0005615 | extracellular space(GO:0005615) |
| 0.5 | 1.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.3 | GO:0005605 | basal lamina(GO:0005605) laminin complex(GO:0043256) |
| 0.1 | 1.0 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 0.9 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.1 | 0.8 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.2 | 0.7 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.7 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 2.9 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 2.7 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.1 | 2.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 2.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 1.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 1.3 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 1.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 1.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 1.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 0.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.7 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.3 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 0.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 1.5 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.4 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 1.1 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.0 | 1.1 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 0.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 0.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |