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PRJNA195909:zebrafish embryo and larva development
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Results for cdc5l
Z-value: 2.28
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Transcription factors associated with cdc5l
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| cdc5l | dr11_v1_chr17_+_5061135_5061135 | 0.95 | 8.7e-05 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_35438300 Show fit | 3.53 |
ENSDART00000102504
ENSDART00000153249 |
tudor domain containing 6 |
|
| chr6_+_40992409 Show fit | 2.93 |
ENSDART00000151419
|
transforming growth factor, alpha |
|
| chr9_+_44994214 Show fit | 2.91 |
ENSDART00000141434
|
retinol saturase (all-trans-retinol 13,14-reductase) like |
|
| chr22_+_25242322 Show fit | 2.63 |
ENSDART00000134628
|
si:ch211-226h8.8 |
|
| chr22_+_25248961 Show fit | 2.61 |
ENSDART00000143079
|
si:ch211-226h8.11 |
|
| chr6_+_40992883 Show fit | 2.45 |
ENSDART00000076061
|
transforming growth factor, alpha |
|
| chr23_-_44574059 Show fit | 2.43 |
ENSDART00000123007
|
si:ch73-160p18.3 |
|
| chr22_+_25236657 Show fit | 2.35 |
ENSDART00000138012
|
zgc:172218 |
|
| chr9_+_34397516 Show fit | 2.31 |
ENSDART00000011304
ENSDART00000192973 |
mediator complex subunit 14 |
|
| chr1_+_12195700 Show fit | 2.18 |
ENSDART00000040307
|
tudor domain containing 7 a |
Network of associatons between targets according to the STRING database.
First level regulatory network of cdc5l
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 6.4 | GO:0030719 | P granule organization(GO:0030719) |
| 0.0 | 5.6 | GO:0051603 | proteolysis involved in cellular protein catabolic process(GO:0051603) |
| 0.6 | 5.4 | GO:2000273 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273) |
| 0.1 | 4.1 | GO:0019827 | stem cell population maintenance(GO:0019827) |
| 0.1 | 3.7 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.4 | 2.5 | GO:0000455 | enzyme-directed rRNA pseudouridine synthesis(GO:0000455) |
| 0.2 | 2.5 | GO:0072595 | maintenance of protein localization in organelle(GO:0072595) |
| 0.1 | 2.3 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.1 | 2.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.2 | 2.2 | GO:0006611 | protein export from nucleus(GO:0006611) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.1 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 4.8 | GO:0005764 | lysosome(GO:0005764) |
| 0.0 | 4.5 | GO:0005730 | nucleolus(GO:0005730) |
| 0.1 | 4.2 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.6 | 4.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 3.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 2.8 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 2.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 2.2 | GO:0043186 | P granule(GO:0043186) |
| 0.0 | 2.2 | GO:0005802 | trans-Golgi network(GO:0005802) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.6 | GO:0003712 | transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712) |
| 0.0 | 6.5 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 5.8 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.2 | 5.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 5.0 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 4.0 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 3.8 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 3.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 2.7 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.5 | 2.3 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.4 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 3.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.9 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 2.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 2.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 1.8 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 1.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 1.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 1.3 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 1.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 3.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 2.2 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.1 | 1.9 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.1 | 1.8 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 1.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 1.3 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 1.2 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 1.2 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 1.1 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |