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PRJNA195909:zebrafish embryo and larva development

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Results for bcl6aa+bcl6ab+bcl6b

Z-value: 0.72

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Transcription factors associated with bcl6aa+bcl6ab+bcl6b

Gene Symbol Gene ID Gene Info
ENSDARG00000069295 BCL6A transcription repressor b
ENSDARG00000069335 BCL6B transcription repressor
ENSDARG00000070864 BCL6A transcription repressor a
ENSDARG00000111395 BCL6A transcription repressor a
ENSDARG00000112502 BCL6A transcription repressor a
ENSDARG00000116260 BCL6A transcription repressor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl6adr11_v1_chr6_-_28222592_28222592-0.665.4e-02Click!
bcl6bdr11_v1_chr7_+_20017211_20017211-0.599.1e-02Click!
bcl6abdr11_v1_chr2_-_10098191_10098191-0.137.5e-01Click!

Activity profile of bcl6aa+bcl6ab+bcl6b motif

Sorted Z-values of bcl6aa+bcl6ab+bcl6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10166297 0.76 ENSDART00000141877
potassium channel, subfamily K, member 10a
chr9_-_43644261 0.59 ENSDART00000023684
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr25_-_29415369 0.53 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr8_-_23240156 0.49 ENSDART00000131632
PTK6 protein tyrosine kinase 6a
chr4_+_19127973 0.47 ENSDART00000136611
si:dkey-21o22.2
chr18_-_46183462 0.46 ENSDART00000021192
potassium channel, subfamily K, member 6
chr11_-_8167799 0.45 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
urate oxidase
chr2_-_38284648 0.45 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
chr3_+_40289418 0.44 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr23_-_14830627 0.41 ENSDART00000134659
Src-like-adaptor 2
chr13_-_37608441 0.40 ENSDART00000140230
zgc:123068
chr18_+_22109379 0.36 ENSDART00000147230
zgc:158868
chr23_+_1033668 0.35 ENSDART00000143391
si:zfos-905g2.1
chr7_-_58776400 0.35 ENSDART00000167433
SRY (sex determining region Y)-box 17
chr9_+_20869166 0.35 ENSDART00000147892
WD repeat domain 3
chr9_-_9225980 0.34 ENSDART00000180301
cystathionine-beta-synthase b
chr22_+_7480465 0.34 ENSDART00000034545
zgc:92745
chr7_+_5529967 0.34 ENSDART00000142709
si:dkeyp-67a8.4
chr10_-_3332362 0.34 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr8_+_1189798 0.33 ENSDART00000193474
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr2_+_13710439 0.33 ENSDART00000155712
EBNA1 binding protein 2
chr8_-_7232413 0.33 ENSDART00000092426
glutamate receptor interacting protein 2a
chr21_+_15870752 0.33 ENSDART00000122015
family with sequence similarity 169, member Ab
chr14_-_28567845 0.31 ENSDART00000126095
preproinsulin b
chr22_+_25289360 0.31 ENSDART00000143782
si:ch211-154a22.8
chr21_+_26720803 0.31 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr8_-_23599096 0.30 ENSDART00000183096
solute carrier family 38, member 5b
chr11_-_22303678 0.30 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr23_-_33558161 0.30 ENSDART00000018301
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr14_-_6987649 0.30 ENSDART00000060990
eukaryotic translation initiation factor 4E binding protein 3, like
chr9_+_40825065 0.29 ENSDART00000137673
si:dkey-95p16.2
chr13_-_31349284 0.29 ENSDART00000145887
ribosomal RNA processing 12 homolog
chr11_-_11791718 0.29 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr10_-_29827000 0.29 ENSDART00000131418
ZPR1 zinc finger
chr24_+_31361407 0.29 ENSDART00000162668
cAMP responsive element modulator b
chr2_-_9989919 0.27 ENSDART00000180213
ENSDART00000184369
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr3_-_6608342 0.27 ENSDART00000161188
si:ch73-59f11.3
chr23_+_42482137 0.27 ENSDART00000160199
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr2_-_38125657 0.26 ENSDART00000143433
cerebellin 12
chr11_+_43375326 0.26 ENSDART00000130131
sulfotransferase family, cytosolic, 6b, member 1
chr17_+_16046314 0.26 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr22_+_26804197 0.26 ENSDART00000135688
si:dkey-44g23.2
chr13_+_33688474 0.26 ENSDART00000161465

chr18_+_45228691 0.25 ENSDART00000127953
LARGE xylosyl- and glucuronyltransferase 2
chr9_+_29430432 0.25 ENSDART00000125632
UDP-glucose glycoprotein glucosyltransferase 2
chr13_-_37631092 0.25 ENSDART00000108855
si:dkey-188i13.7
chr2_+_327081 0.25 ENSDART00000155595
zgc:174263
chr16_+_40954481 0.25 ENSDART00000058587
glycogen synthase kinase binding protein
chr24_-_2829049 0.24 ENSDART00000164913
si:ch211-152c8.5
chr7_+_38809241 0.24 ENSDART00000190979
harbinger transposase derived 1
chr17_-_21278582 0.24 ENSDART00000157518
heat shock protein 12A
chr17_+_24597001 0.24 ENSDART00000191834
rearranged L-myc fusion
chr1_+_35495368 0.24 ENSDART00000053806
GRB2-associated binding protein 1
chr5_+_36895545 0.24 ENSDART00000135776
ENSDART00000147561
ENSDART00000133842
ENSDART00000051185
ENSDART00000141984
ENSDART00000136301
ENSDART00000142388
serine/arginine-rich splicing factor 7a
chr17_-_21278846 0.24 ENSDART00000181356
heat shock protein 12A
chr5_-_25582721 0.23 ENSDART00000123986
annexin A1a
chr9_-_12401871 0.23 ENSDART00000191901
nucleoporin 35
chr14_-_38828057 0.23 ENSDART00000186088
spindle apparatus coiled-coil protein 1
chr6_+_37655078 0.23 ENSDART00000122199
ENSDART00000065127
cytoplasmic FMR1 interacting protein 1
chr18_-_8378251 0.23 ENSDART00000192807
selenophosphate synthetase 1
chr15_-_40246396 0.23 ENSDART00000063777
potassium inwardly-rectifying channel, subfamily J, member 13
chr2_-_57344037 0.23 ENSDART00000148873
transcription factor 3a
chr20_-_34767472 0.23 ENSDART00000186710
progestin and adipoQ receptor family member VIII
chr1_-_9195629 0.22 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr23_+_42396934 0.22 ENSDART00000169821
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr21_-_30026359 0.22 ENSDART00000153645
PWWP domain containing 2A
chr23_+_4350897 0.22 ENSDART00000190593
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr8_+_22359881 0.22 ENSDART00000187867
zgc:153631
chr15_+_880751 0.22 ENSDART00000156724
si:dkey-7i4.10
chr5_+_29160324 0.22 ENSDART00000137324
dipeptidyl-peptidase 7
chr6_+_26948093 0.22 ENSDART00000153595
FERM, RhoGEF and pleckstrin domain protein 2
chr14_-_21123325 0.22 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
chr19_-_8798178 0.21 ENSDART00000188232
ceramide synthase 2a
chr3_+_39656188 0.21 ENSDART00000186292
ENSDART00000156038
epsin 2
chr20_-_37813863 0.21 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr3_-_60602432 0.20 ENSDART00000163235
serine/arginine-rich splicing factor 2b
chr5_+_50953240 0.20 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr20_+_25625872 0.20 ENSDART00000078385
phosphoribosyl pyrophosphate amidotransferase
chr20_-_33704753 0.20 ENSDART00000157427
rho-associated, coiled-coil containing protein kinase 2b
chr5_-_29195063 0.20 ENSDART00000109926
mannosidase, alpha, class 1B, member 1b
chr11_+_19603251 0.20 ENSDART00000005639
THO complex 7
chr7_-_26627252 0.19 ENSDART00000164050
ENSDART00000159826
PHD finger protein 23b
chr18_+_14684115 0.19 ENSDART00000108469
spermatogenesis associated 2-like
chr22_+_26400519 0.19 ENSDART00000159839
ENSDART00000144585
calpain 8
chr17_+_16046132 0.19 ENSDART00000155005
si:ch73-204p21.2
chr11_-_2297832 0.19 ENSDART00000158266
zinc finger protein 740a
chr12_-_1031970 0.19 ENSDART00000105292
polymerase (RNA) III (DNA directed) polypeptide E
chr15_+_20239141 0.18 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr10_-_42147318 0.18 ENSDART00000134890
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr1_-_50791280 0.18 ENSDART00000181224

chr16_+_16849220 0.18 ENSDART00000047409
ENSDART00000142155
myosin, heavy chain 14, non-muscle
chr23_-_19682971 0.18 ENSDART00000048891
zgc:193598
chr1_-_20068155 0.18 ENSDART00000102993
methyltransferase like 14
chr12_-_33972798 0.18 ENSDART00000105545
ADP-ribosylation factor-like 3
chr22_+_3238474 0.17 ENSDART00000157954
si:ch1073-178p5.3
chr17_-_31308658 0.17 ENSDART00000124505
bromo adjacent homology domain containing 1
chr17_+_4368859 0.17 ENSDART00000055385
cardiolipin synthase 1
chr5_+_36895860 0.17 ENSDART00000134493
serine/arginine-rich splicing factor 7a
chr6_-_12296170 0.16 ENSDART00000155685
plakophilin 4
chr24_+_39027481 0.16 ENSDART00000085565
calpain 15
chr2_+_26237322 0.16 ENSDART00000030520
paralemmin 1b
chr12_-_4243268 0.16 ENSDART00000131275
zgc:92313
chr23_+_42346799 0.16 ENSDART00000159985
ENSDART00000172144
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr17_+_34206167 0.16 ENSDART00000136167
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr19_-_47782916 0.16 ENSDART00000063337
cell division cycle associated 8
chr20_+_39457598 0.16 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr25_-_13408760 0.16 ENSDART00000154445
GINS complex subunit 3
chr16_-_45917322 0.16 ENSDART00000060822
antifreeze protein type IV
chr10_+_40324395 0.16 ENSDART00000147205
glycolipid transfer protein b
chr16_-_41667101 0.16 ENSDART00000084528
ATPase secretory pathway Ca2+ transporting 1
chr19_-_30420602 0.15 ENSDART00000144121
protein phosphatase 1, regulatory subunit 10
chr3_-_3703572 0.15 ENSDART00000111017
si:ch211-163m16.7
chr19_-_20777351 0.15 ENSDART00000019206
N-glycanase 1
chr6_+_13046720 0.15 ENSDART00000165896
caspase 8, apoptosis-related cysteine peptidase
chr2_+_23808640 0.15 ENSDART00000024619
golgi reassembly stacking protein 1a
chr16_+_10330178 0.15 ENSDART00000121966
mediator of DNA damage checkpoint 1
chr11_+_10548171 0.15 ENSDART00000191497
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr2_+_44972720 0.15 ENSDART00000075146
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr16_+_10329701 0.15 ENSDART00000172845
mediator of DNA damage checkpoint 1
chr21_-_2238277 0.15 ENSDART00000165754
si:dkey-50i6.6
chr9_-_12659140 0.15 ENSDART00000058565
PTTG1 interacting protein b
chr17_-_30521043 0.15 ENSDART00000087111
intersectin 2b
chr16_+_42772678 0.15 ENSDART00000155575
si:ch211-135n15.2
chr19_+_43885770 0.15 ENSDART00000135599
lysophospholipase II
chr21_+_34122801 0.14 ENSDART00000182627
high mobility group box 3b
chr17_-_45378473 0.14 ENSDART00000132969
zinc finger protein 106a
chr7_+_26029672 0.14 ENSDART00000101126
arachidonate 12-lipoxygenase
chr10_-_39281475 0.14 ENSDART00000175136
cryptochrome circadian clock 5
chr25_+_16915974 0.14 ENSDART00000188923
zgc:77158
chr22_+_1462177 0.14 ENSDART00000164685
si:dkeyp-53d3.5
chr18_-_20444296 0.14 ENSDART00000132993
kinesin family member 23
chr2_-_7185460 0.14 ENSDART00000092078
ring finger and CCCH-type domains 1b
chr1_-_56596701 0.14 ENSDART00000133693

chr13_+_25549425 0.14 ENSDART00000087553
ENSDART00000169199
SEC23 interacting protein
chr8_+_11687254 0.14 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr5_-_68495224 0.13 ENSDART00000187955
eph receptor B4a
chr5_-_25066780 0.13 ENSDART00000002118
ENSDART00000182575
patatin-like phospholipase domain containing 7b
chr23_+_45229198 0.13 ENSDART00000172445
tetratricopeptide repeat domain 39B
chr9_-_55772937 0.13 ENSDART00000159192
A kinase (PRKA) anchor protein 17A
chr21_+_17541634 0.13 ENSDART00000191700
ENSDART00000163238
stomatin
chr3_+_24511959 0.13 ENSDART00000133898
dynein, axonemal, light chain 4a
chr5_+_28849155 0.13 ENSDART00000079090
zgc:174259
chr8_-_23783633 0.13 ENSDART00000132657
si:ch211-163l21.7
chr10_+_585719 0.13 ENSDART00000180167
SMAD family member 4a
chr2_-_9744081 0.13 ENSDART00000097732
dishevelled segment polarity protein 3a
chr15_+_22333778 0.13 ENSDART00000114937
phosphodiesterase 9A like
chr7_-_54320088 0.13 ENSDART00000172396
Fas (tnfrsf6)-associated via death domain
chr2_+_45100963 0.13 ENSDART00000160122

chr3_+_50172452 0.13 ENSDART00000191224
epsin 3a
chr19_+_47783137 0.13 ENSDART00000024777
ENSDART00000158979
c19h1orf109 homolog (H. sapiens)
chr8_+_47099033 0.13 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr20_+_27087539 0.13 ENSDART00000062094
transmembrane protein 251
chr3_+_62236443 0.13 ENSDART00000180482
ENSDART00000193718

chr22_-_22242884 0.12 ENSDART00000020937
HDGF like 2
chr6_-_11800427 0.12 ENSDART00000126243
membrane-associated ring finger (C3HC4) 7
chr25_-_17395315 0.12 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr11_-_38914265 0.12 ENSDART00000141229
si:ch211-122l14.4
chr10_-_40557210 0.12 ENSDART00000135297
trace amine associated receptor 18b
chr7_+_26549846 0.12 ENSDART00000141353
tyrosine kinase, non-receptor, 1
chr19_+_14352332 0.12 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr9_-_27738110 0.12 ENSDART00000060347
crystallin, gamma S2
chr25_+_11281970 0.12 ENSDART00000180094
si:dkey-187e18.1
chr7_-_22941472 0.12 ENSDART00000190334
TNF superfamily member 10, like
chr1_-_44928987 0.12 ENSDART00000134635
si:dkey-9i23.15
chr17_-_28811747 0.12 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase
chr1_+_10318089 0.12 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr6_-_7726849 0.12 ENSDART00000151511
solute carrier family 25, member 38b
chr12_-_13337033 0.12 ENSDART00000105903
ENSDART00000139786
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr18_+_3243292 0.12 ENSDART00000166580
p21 protein (Cdc42/Rac)-activated kinase 1
chr14_+_7932973 0.11 ENSDART00000109941
CXXC finger protein 5b
chr4_+_76306625 0.11 ENSDART00000193823
ENSDART00000180622
si:ch73-389k6.1
chr13_-_8888334 0.11 ENSDART00000059881
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr3_-_7147226 0.11 ENSDART00000178155

chr11_-_43226255 0.11 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr3_+_32492467 0.11 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr14_+_29945070 0.11 ENSDART00000185039
family with sequence similarity 149 member A
chr1_-_47114310 0.11 ENSDART00000144899
ENSDART00000053157
SET domain containing 4
chr7_+_12950507 0.11 ENSDART00000067629
ENSDART00000158004
serum amyloid A
chr11_-_40742424 0.11 ENSDART00000173399
ENSDART00000021369
taste receptor, type 1, member 3
chr8_-_19246342 0.11 ENSDART00000147172
abhydrolase domain containing 17Ab
chr3_+_62219158 0.11 ENSDART00000162354

chr3_+_35608385 0.11 ENSDART00000193219
ENSDART00000132703
TNF receptor-associated factor 7
chr10_+_40284003 0.11 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
G protein-coupled receptor kinase interacting ArfGAP 2b
chr11_-_287670 0.11 ENSDART00000035737
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr3_+_12861158 0.11 ENSDART00000171237
potassium inwardly-rectifying channel, subfamily J, member 2b
chr3_-_50998577 0.11 ENSDART00000157735
CDC42 effector protein (Rho GTPase binding) 4a
chr24_+_10397865 0.11 ENSDART00000155557
si:ch211-69l10.4
chr17_+_7522777 0.11 ENSDART00000184723
kelch-like family member 10b, tandem duplicate 2
chr3_-_52661242 0.11 ENSDART00000138018
zgc:113210
chr19_+_28291376 0.11 ENSDART00000139433
ENSDART00000103855
lysophosphatidylcholine acyltransferase 1
chr3_-_60589292 0.10 ENSDART00000157822
jumonji domain containing 6
chr16_+_25343934 0.10 ENSDART00000109710
zinc finger and AT hook domain containing
chr8_+_23711842 0.10 ENSDART00000128783
peroxisome proliferator-activated receptor delta b
chr4_-_73739119 0.10 ENSDART00000108669
zgc:171551
chr3_+_60589157 0.10 ENSDART00000165367
methyltransferase like 23
chr3_-_30888415 0.10 ENSDART00000124458
lysine methyltransferase 5C
chr7_+_14005111 0.10 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr23_+_42292748 0.10 ENSDART00000166113
ENSDART00000158684
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr23_-_1571682 0.10 ENSDART00000013635
F-box protein 30b
chr20_+_25581627 0.10 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl6aa+bcl6ab+bcl6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 0.3 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.3 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.2 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.1 0.2 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.0 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.2 GO:0033028 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.3 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0006999 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.1 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0002370 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.6 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0030669 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687) nuclear periphery(GO:0034399)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.2 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.5 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 1.2 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation