ISMARA results: batf2+batf3

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PRJNA195909:zebrafish embryo and larva development

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Results for batf2+batf3

Z-value: 1.37

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Transcription factors associated with batf2+batf3

Gene Symbol	Gene ID	Gene Info
batf3 NCBI UniProt	ENSDARG00000042577	basic leucine zipper transcription factor, ATF-like 3
batf2 NCBI UniProt	ENSDARG00000105562	si_dkey-23i12.7

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
batf3	dr11_v1_chr20_-_37813863_37813863	0.94	2.0e-04	Click!
si:dkey-23i12.7	dr11_v1_chr7_+_25049545_25049577	-0.16	6.7e-01	Click!

Activity profile of batf2+batf3 motif

Sorted Z-values of batf2+batf3 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_-_29387215 Show fit	3.52	ENSDART00000148787	s100a1 NCBI UniProt Show fit	S100 calcium binding protein A1
chr16_+_27614989 Show fit	3.34	ENSDART00000005625	glipr2l NCBI UniProt Show fit	GLI pathogenesis-related 2, like
chr23_-_1571682 Show fit	2.37	ENSDART00000013635	fbxo30b NCBI UniProt Show fit	F-box protein 30b
chr15_+_34963316 Show fit	2.17	ENSDART00000153840	si:ch73-95l15.5 NCBI UniProt Show fit	si:ch73-95l15.5
chr25_-_6447835 Show fit	2.10	ENSDART00000012820	snupn NCBI UniProt Show fit	snurportin 1
chr3_-_40658820 Show fit	2.04	ENSDART00000191948	rnf216 NCBI UniProt Show fit	ring finger protein 216
chr6_+_475264 Show fit	1.89	ENSDART00000193615	LO017974.1 NCBI UniProt Show fit
chr17_+_15674052 Show fit	1.89	ENSDART00000156726	bach2a NCBI UniProt Show fit	BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr16_-_41667101 Show fit	1.84	ENSDART00000084528	atp2c1 NCBI UniProt Show fit	ATPase secretory pathway Ca2+ transporting 1
chr25_-_6448050 Show fit	1.82	ENSDART00000180616	snupn NCBI UniProt Show fit	snurportin 1

Showing 1 to 10 of 76 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of batf2+batf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.2	GO:0008016	regulation of heart contraction(GO:0008016)
1.0	3.9	GO:0061015	RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.5	2.4	GO:1901842	regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	1.9	GO:0021549	cerebellum development(GO:0021549)
0.4	1.8	GO:0055071	manganese ion homeostasis(GO:0055071)
0.4	1.6	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1	1.6	GO:0006896	Golgi to vacuole transport(GO:0006896)
0.0	1.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.2	0.8	GO:0060019	radial glial cell differentiation(GO:0060019)
0.0	0.7	GO:0072554	endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)

Showing 1 to 10 of 16 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.6	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	1.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	0.9	GO:0071007	U2-type catalytic step 2 spliceosome(GO:0071007)
0.2	0.8	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1	0.6	GO:0008091	spectrin(GO:0008091)
0.0	0.6	GO:0000815	ESCRT III complex(GO:0000815)

Showing 1 to 6 of 6 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.9	GO:0061608	nuclear import signal receptor activity(GO:0061608)
0.1	3.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	2.4	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	2.3	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	2.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3	1.8	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	1.6	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	1.6	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	1.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.2	1.2	GO:1990756	protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)

Showing 1 to 10 of 16 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Total log-likelihood	Term	Description
3.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events

Showing 1 to 5 of 5 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	1.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse

Showing 1 to 7 of 7 entries

Results for batf2+batf3

Z-value: 1.37

Motif logo

Transcription factors associated with batf2+batf3

Activity-expression correlation:

Activity profile of batf2+batf3 motif

Sorted Z-values of batf2+batf3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of batf2+batf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: