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PRJNA195909:zebrafish embryo and larva development

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Results for barx1

Z-value: 1.00

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Transcription factors associated with barx1

Gene Symbol Gene ID Gene Info
ENSDARG00000007407 BARX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barx1dr11_v1_chr11_+_27543093_275430930.571.1e-01Click!

Activity profile of barx1 motif

Sorted Z-values of barx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 3.72 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr16_-_55028740 2.41 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr23_+_20422661 2.22 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr14_+_46313396 1.78 ENSDART00000047525
crystallin, beta A1, like 1
chr5_+_32206378 1.75 ENSDART00000126873
ENSDART00000051361
myosin, heavy polypeptide 2, fast muscle specific
chr3_+_60721342 1.67 ENSDART00000157772
forkhead box J1a
chr13_+_1726953 1.66 ENSDART00000103004
zmp:0000000760
chr25_+_20089986 1.40 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr18_-_49318823 1.37 ENSDART00000098419
sb:cb81
chr4_+_9669717 1.37 ENSDART00000004604
si:dkey-153k10.9
chr2_-_7666021 1.33 ENSDART00000180007

chr2_+_22795494 1.31 ENSDART00000042255
RAB6B, member RAS oncogene family b
chr21_+_39185461 1.25 ENSDART00000178419
crystallin, beta A1b
chr14_-_26536504 1.19 ENSDART00000105933
transforming growth factor, beta-induced
chr3_-_55128258 1.18 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr5_-_66702479 1.16 ENSDART00000129197
meningioma 1b
chr2_-_31767827 1.13 ENSDART00000114928
actinodin2
chr12_-_16898140 1.10 ENSDART00000152656
Cathepsin L1-like
chr5_+_24305877 1.08 ENSDART00000144226
cathepsin L, like
chr5_-_41531629 1.07 ENSDART00000051082
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr12_-_16923162 1.06 ENSDART00000106072
si:dkey-26g8.5
chr1_+_53374454 1.04 ENSDART00000038807
uncoupling protein 1
chr17_-_29224908 0.99 ENSDART00000156288
si:dkey-28g23.6
chr12_+_27141140 0.96 ENSDART00000136415
homeobox B1b
chr17_+_4030493 0.96 ENSDART00000151849
hydroxyacid oxidase (glycolate oxidase) 1
chr14_+_46313135 0.92 ENSDART00000172902
crystallin, beta A1, like 1
chr3_-_61205711 0.91 ENSDART00000055062
parvalbumin 1
chr22_+_26400519 0.90 ENSDART00000159839
ENSDART00000144585
calpain 8
chr22_+_12770877 0.86 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr9_-_42484444 0.83 ENSDART00000048320
ENSDART00000047653
tissue factor pathway inhibitor a
chr23_-_21453614 0.83 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr19_+_8973042 0.81 ENSDART00000039597
cellular retinoic acid binding protein 2, b
chr14_+_7140997 0.81 ENSDART00000170994
ENSDART00000129898
cathepsin F
chr19_-_10554240 0.80 ENSDART00000104539
ENSDART00000144923
lens intrinsic membrane protein 2.4
chr14_-_25599002 0.80 ENSDART00000040955
solute carrier family 25, member 48
chr1_+_59293873 0.79 ENSDART00000168036
retinol dehydrogenase 8b
chr9_-_22135576 0.79 ENSDART00000101902
crystallin, gamma M2d8
chr7_+_22675475 0.79 ENSDART00000134423
plac8 onzin related protein 3
chr10_+_1396940 0.79 ENSDART00000150096
glial cell derived neurotrophic factor a
chr4_+_76575585 0.79 ENSDART00000131588
membrane-spanning 4-domains, subfamily A, member 17A.11
chr22_+_10651726 0.78 ENSDART00000145459
Ras association (RalGDS/AF-6) domain family 1
chr12_-_16720432 0.77 ENSDART00000152261
ENSDART00000152154
si:dkey-26g8.4
chr22_-_15587360 0.76 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr11_-_17981421 0.75 ENSDART00000005999
ENSDART00000104046
twinfilin actin-binding protein 2b
chr15_-_15357178 0.75 ENSDART00000106120
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr7_+_29954709 0.73 ENSDART00000173904
alpha-tropomyosin
chr3_+_59851537 0.72 ENSDART00000180997

chr1_-_614583 0.71 ENSDART00000004062
ENSDART00000147937
ENSDART00000146351
ENSDART00000134456
ATP synthase peripheral stalk subunit F6
chr6_+_25257728 0.71 ENSDART00000162581
kynurenine aminotransferase 3
chr12_+_27127139 0.70 ENSDART00000025966
homeobox B6b
chr24_+_21622373 0.70 ENSDART00000183611
ribosomal protein L21
chr15_+_32711663 0.69 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr1_+_47459723 0.69 ENSDART00000015046
follistatin-like 1a
chr13_-_36535128 0.69 ENSDART00000043312
serine/arginine-rich splicing factor 5a
chr12_+_48216662 0.68 ENSDART00000187369
leucine rich repeat containing 20
chr9_+_53337974 0.68 ENSDART00000145138
dopachrome tautomerase
chr5_-_64831207 0.67 ENSDART00000144816
limb and CNS expressed 1
chr2_-_32356539 0.67 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr14_-_498979 0.66 ENSDART00000171976
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr21_-_26071773 0.66 ENSDART00000141382
RAB34, member RAS oncogene family b
chr15_+_28685625 0.65 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr4_+_14660769 0.64 ENSDART00000168152
ENSDART00000013990
ENSDART00000079987
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr20_+_15015557 0.64 ENSDART00000039345
myocilin
chr4_+_2252123 0.64 ENSDART00000163996
ENSDART00000066491
GLI pathogenesis-related 1a
chr9_-_48370645 0.63 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr9_-_18911608 0.62 ENSDART00000138785
si:dkey-239h2.3
chr17_+_41992054 0.62 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr9_-_32753535 0.62 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr24_-_6078222 0.62 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr6_-_57655299 0.62 ENSDART00000083807
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr11_+_30729745 0.61 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr3_-_39488482 0.61 ENSDART00000135192
zgc:100868
chr22_+_3153876 0.60 ENSDART00000163327
ribosomal protein L36
chr12_+_47663419 0.60 ENSDART00000171932
hematopoietically expressed homeobox
chr3_-_36260102 0.60 ENSDART00000126588
Rac family small GTPase 3a
chr21_+_25765734 0.59 ENSDART00000021664
claudin b
chr21_+_26071874 0.59 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr2_+_54641644 0.59 ENSDART00000027313
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr3_+_26081343 0.59 ENSDART00000134647
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr25_+_5044780 0.58 ENSDART00000153980
parvin, beta
chr5_+_12515402 0.58 ENSDART00000103278
zgc:171242
chr10_-_29903165 0.58 ENSDART00000078800
lens intrinsic membrane protein 2.1
chr6_-_58764672 0.57 ENSDART00000154322
sterol O-acyltransferase 2
chr6_+_7123980 0.57 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
chr11_+_14199802 0.57 ENSDART00000102520
ENSDART00000133172
paralemmin 1a
chr12_+_48220584 0.57 ENSDART00000164392
leucine rich repeat containing 20
chr2_-_689047 0.57 ENSDART00000122732
forkhead box C1a
chr13_-_4223955 0.57 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr16_+_40576679 0.56 ENSDART00000169412
ENSDART00000193464
cyclin E2
chr1_-_21723329 0.56 ENSDART00000137138
si:ch211-134c9.2
chr5_-_63515210 0.56 ENSDART00000022348
PR domain containing 12b
chr8_-_2230128 0.56 ENSDART00000140427
si:dkeyp-117b11.2
chr6_-_13187168 0.56 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr4_+_76705830 0.56 ENSDART00000064312
membrane-spanning 4-domains, subfamily A, member 17A.7
chr7_-_26408472 0.56 ENSDART00000111494
galactose-3-O-sulfotransferase 4
chr23_-_5719453 0.55 ENSDART00000033093
ladinin
chr20_-_29052391 0.55 ENSDART00000193482
ENSDART00000017090
thrombospondin 1b
chr7_+_15872357 0.55 ENSDART00000165757
paired box 6b
chr19_+_43969363 0.54 ENSDART00000051712
GATA zinc finger domain containing 1
chr12_+_39034225 0.54 ENSDART00000154064
si:dkey-239b22.2
chr14_-_1998501 0.53 ENSDART00000189052
protocadherin 2 gamma 5
chr20_-_40370736 0.53 ENSDART00000041229
fatty acid binding protein 7, brain, b
chr5_-_41494831 0.52 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr21_-_19316985 0.52 ENSDART00000141596
glycerol-3-phosphate acyltransferase 3
chr6_-_15757867 0.52 ENSDART00000063665
atypical chemokine receptor 3b
chr1_-_54063520 0.52 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr1_+_52929185 0.52 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr10_+_38610741 0.51 ENSDART00000126444
matrix metallopeptidase 13a
chr3_-_22212764 0.51 ENSDART00000155490
microtubule-associated protein tau b
chr23_+_4689626 0.51 ENSDART00000131532
glycoprotein IX (platelet)
chr19_+_42609132 0.51 ENSDART00000010104
cartilage associated protein
chr1_-_10647484 0.51 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
chr5_+_42280372 0.50 ENSDART00000142855
T-box 6, like
chr1_+_52392511 0.50 ENSDART00000144025
si:ch211-217k17.8
chr25_+_14507567 0.50 ENSDART00000015681
developing brain homeobox 1b
chr24_-_32408404 0.50 ENSDART00000144157
si:ch211-56a11.2
chr23_-_22650992 0.50 ENSDART00000079007
carbonic anhydrase VI
chr19_-_12145765 0.49 ENSDART00000032474
poly A binding protein, cytoplasmic 1 b
chr16_-_35952789 0.49 ENSDART00000180118
eva-1 homolog Ba (C. elegans)
chr23_+_19813677 0.49 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr1_-_22678471 0.48 ENSDART00000128918
fibroblast growth factor binding protein 1b
chr6_-_54180699 0.48 ENSDART00000045901
ribosomal protein S10
chr7_-_26087807 0.48 ENSDART00000052989
acetylcholinesterase
chr24_-_26302375 0.48 ENSDART00000130696
COP9 signalosome subunit 9
chr21_-_5881344 0.47 ENSDART00000009241
ribosomal protein L35
chr14_+_35691889 0.47 ENSDART00000074685
glycine receptor, beta b
chr1_-_17569793 0.47 ENSDART00000125125
acyl-CoA synthetase long chain family member 1a
chr3_-_12930217 0.47 ENSDART00000166322
platelet-derived growth factor alpha polypeptide b
chr23_+_43493408 0.46 ENSDART00000191441
zinc finger protein 341
chr10_-_9410068 0.46 ENSDART00000041382
MORN repeat containing 5
chr15_-_47865063 0.46 ENSDART00000151600
H3 histone, family 3B.1
chr6_+_13779857 0.46 ENSDART00000154793
transmembrane protein 198b
chr21_+_10828828 0.46 ENSDART00000136449
O-acyltransferase like
chr2_-_10192459 0.45 ENSDART00000128535
ENSDART00000017173
diencephalon/mesencephalon homeobox 1a
chr20_+_38032143 0.45 ENSDART00000032161
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_+_54908895 0.45 ENSDART00000145652
golgin A7 family, member Ba
chr7_+_59169081 0.44 ENSDART00000167980
oligosaccharyltransferase complex subunit
chr2_-_1514001 0.44 ENSDART00000057736
complement component 8, beta polypeptide
chr20_-_19422496 0.44 ENSDART00000143658
si:ch211-278j3.3
chr4_+_31293362 0.44 ENSDART00000169781
si:dkey-57l19.1
chr1_-_17570013 0.44 ENSDART00000146946
acyl-CoA synthetase long chain family member 1a
chr18_+_7345417 0.44 ENSDART00000041429
GLI pathogenesis-related 1b
chr7_+_20471315 0.44 ENSDART00000173714
si:dkey-19b23.13
chr17_-_6730247 0.44 ENSDART00000031091
visinin-like 1b
chr9_-_2594410 0.44 ENSDART00000188306
ENSDART00000164276
sp9 transcription factor
chr9_+_13120419 0.44 ENSDART00000141005
family with sequence similarity 117, member Bb
chr25_-_10564721 0.44 ENSDART00000154776
galanin/GMAP prepropeptide
chr15_-_42206890 0.43 ENSDART00000015843
paired box 3b
chr22_+_11857356 0.43 ENSDART00000179540
muscle RAS oncogene homolog
chr20_-_4738101 0.43 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
poly(A) polymerase alpha
chr12_+_8168272 0.43 ENSDART00000054092
AT-rich interaction domain 5B
chr24_-_37680917 0.43 ENSDART00000131342
ankyrin repeat and sterile alpha motif domain containing 3
chr22_-_26005894 0.43 ENSDART00000105088
platelet-derived growth factor alpha polypeptide a
chr7_-_69636502 0.43 ENSDART00000126739
tetraspanin 5a
chr10_-_40968095 0.43 ENSDART00000184104
neuropeptide FF receptor 1 like 1
chr16_-_50175069 0.42 ENSDART00000192979
lens intrinsic membrane protein 2.5
chr17_+_21919131 0.42 ENSDART00000048136
HtrA serine peptidase 1a
chr11_-_45138857 0.42 ENSDART00000166501
calcium activated nucleotidase 1b
chr15_-_17960228 0.42 ENSDART00000155898
pleckstrin homology-like domain, family B, member 1b
chr21_+_22423286 0.42 ENSDART00000133190
calcyphosine-like b
chr4_-_22671469 0.42 ENSDART00000050753
CD36 molecule (thrombospondin receptor)
chr23_+_409578 0.42 ENSDART00000008177
solute carrier family 25, member 55b
chr25_-_29134654 0.41 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr1_+_25696798 0.41 ENSDART00000054228
lecithin retinol acyltransferase a
chr25_-_22187397 0.41 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr16_+_7653905 0.41 ENSDART00000081431
popeye domain containing 3
chr4_-_9722568 0.41 ENSDART00000067190
tetraspanin 9b
chr7_-_30174882 0.41 ENSDART00000110409
FERM domain containing 5
chr21_+_26726936 0.41 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr19_+_10847118 0.41 ENSDART00000189784
apolipoprotein A-IV a
chr15_-_22074315 0.41 ENSDART00000149830
dopamine receptor D2a
chr4_-_18954001 0.41 ENSDART00000144814
si:dkey-31f5.8
chr10_-_20669635 0.41 ENSDART00000131361
Kv channel interacting protein 3b, calsenilin
chr14_-_4076480 0.40 ENSDART00000059231
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr2_+_16160906 0.40 ENSDART00000135783
selenoprotein J
chr4_+_5796761 0.40 ENSDART00000164854
si:ch73-352p4.8
chr21_-_16113477 0.40 ENSDART00000147588
cytochrome b561 family, member A3b
chr16_+_31921812 0.40 ENSDART00000176928
ENSDART00000193733
ribosomal protein S9
chr16_+_16968682 0.40 ENSDART00000111074
si:ch211-120k19.1
chr7_+_34290051 0.39 ENSDART00000123498
fin bud initiation factor b
chr5_+_67448664 0.39 ENSDART00000105731
si:dkey-251i10.1
chr17_+_29276544 0.39 ENSDART00000049399
ankyrin repeat domain 9
chr16_-_17072440 0.39 ENSDART00000002493
ENSDART00000178443
tumor necrosis factor receptor superfamily, member 1a
chr7_+_41295974 0.39 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
chr8_-_13574764 0.38 ENSDART00000076561
si:ch211-126g16.10
chr21_-_44104600 0.38 ENSDART00000044599
organic anion transporter X
chr1_-_44157273 0.38 ENSDART00000166618
solute carrier family 43, member 3a
chr5_-_26093945 0.38 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr9_-_9348058 0.38 ENSDART00000132257
zgc:113337
chr6_+_56141852 0.38 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr10_+_9410304 0.38 ENSDART00000080843
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr8_-_18537866 0.38 ENSDART00000148802
ENSDART00000148962
ENSDART00000149506
nexilin (F actin binding protein)
chr18_+_46382484 0.38 ENSDART00000024202
ENSDART00000142790
dynein assembly factor with WDR repeat domains 1
chr1_-_10647307 0.37 ENSDART00000103548
si:dkey-31e10.1
chr7_-_34192834 0.37 ENSDART00000125131
SMAD family member 6a
chr16_+_42772678 0.37 ENSDART00000155575
si:ch211-135n15.2
chr1_-_35924495 0.37 ENSDART00000184424
SMAD family member 1
chr13_+_7442023 0.37 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr14_-_13048355 0.37 ENSDART00000166434
si:dkey-35h6.1
chr6_+_34028532 0.37 ENSDART00000155827
si:ch73-185c24.2

Network of associatons between targets according to the STRING database.

First level regulatory network of barx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 0.9 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 0.8 GO:0090190 regulation of neurotransmitter uptake(GO:0051580) regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2 0.7 GO:2000648 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.2 0.7 GO:0003156 regulation of organ formation(GO:0003156)
0.2 0.8 GO:0021742 abducens nucleus development(GO:0021742)
0.2 0.8 GO:0006844 acyl carnitine transport(GO:0006844)
0.2 4.0 GO:0014823 response to activity(GO:0014823)
0.2 0.6 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.5 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.7 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.6 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.6 GO:0072314 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.4 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 1.0 GO:0021661 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.1 1.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.5 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.1 1.0 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.4 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 1.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.5 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 5.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.3 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.1 0.2 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.4 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.6 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.1 0.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.3 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.8 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.1 0.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 0.2 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 0.5 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.2 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.6 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 0.6 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.3 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:0009099 leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.2 GO:0046385 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.1 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:2000379 positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.1 0.3 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.3 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.5 GO:0048008 positive regulation of protein autophosphorylation(GO:0031954) platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.2 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.6 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.8 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.1 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 2.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.5 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.4 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.2 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.3 GO:0006788 heme oxidation(GO:0006788)
0.0 0.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.4 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 4.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.4 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.3 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.1 GO:0072679 thymocyte migration(GO:0072679)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.7 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.8 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507) tolerance induction to self antigen(GO:0002513)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.5 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 1.0 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.2 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.3 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.0 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.3 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.2 GO:0007596 blood coagulation(GO:0007596)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.5 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0016203 muscle attachment(GO:0016203)
0.0 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.4 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 1.2 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.8 GO:0033333 fin development(GO:0033333)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0001881 receptor recycling(GO:0001881)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.6 GO:1990266 granulocyte migration(GO:0097530) neutrophil migration(GO:1990266)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.9 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.9 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.1 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0033198 response to ATP(GO:0033198)
0.0 0.6 GO:0060326 cell chemotaxis(GO:0060326)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 GO:0005861 troponin complex(GO:0005861)
0.2 0.5 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.3 GO:0034359 mature chylomicron(GO:0034359)
0.1 3.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 3.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 2.3 GO:0031674 I band(GO:0031674)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 2.4 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.8 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.2 0.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.9 GO:0016841 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.2 0.5 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.2 0.8 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.6 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.4 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 0.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.3 GO:0030975 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0004104 cholinesterase activity(GO:0004104)
0.1 6.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.1 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.2 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 0.3 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.6 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.2 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 0.3 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 5.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 3.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.1 GO:0005231 excitatory extracellular ligand-gated ion channel activity(GO:0005231)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 5.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK