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PRJNA195909:zebrafish embryo and larva development

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Results for barhl1a+barhl1b

Z-value: 2.87

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Transcription factors associated with barhl1a+barhl1b

Gene Symbol Gene ID Gene Info
ENSDARG00000019013 BarH-like homeobox 1b
ENSDARG00000035508 BarH-like homeobox 1a
ENSDARG00000110061 BarH-like homeobox 1a
ENSDARG00000112355 BarH-like homeobox 1a
ENSDARG00000113145 BarH-like homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barhl1bdr11_v1_chr21_-_17482465_17482465-0.964.1e-05Click!
barhl1adr11_v1_chr5_-_29750377_29750377-0.835.3e-03Click!

Activity profile of barhl1a+barhl1b motif

Sorted Z-values of barhl1a+barhl1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_45320126 4.47 ENSDART00000133572
si:ch73-90k17.1
chr18_-_20674121 3.71 ENSDART00000005145
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr14_+_32918172 3.59 ENSDART00000182867
ligand of numb-protein X 2b
chr6_-_8362419 3.49 ENSDART00000142752
ENSDART00000135810
acid phosphatase 5a, tartrate resistant
chr7_+_25126629 3.35 ENSDART00000077217
zgc:101765
chr10_+_6884123 3.19 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr23_-_44577885 3.09 ENSDART00000166654
si:ch73-160p18.4
chr14_-_46198373 3.08 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr1_+_10129099 3.08 ENSDART00000187740
RNA binding motif protein 46
chr14_+_32918484 2.98 ENSDART00000105721
ligand of numb-protein X 2b
chr23_-_25779995 2.78 ENSDART00000110670
si:dkey-21c19.3
chr1_+_53321878 2.69 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr24_-_20599781 2.68 ENSDART00000179664
ENSDART00000141823
zinc finger and BTB domain containing 47b
chr16_+_11779534 2.65 ENSDART00000133497
si:dkey-250k15.4
chr12_+_23664335 2.63 ENSDART00000111334
mitochondrial poly(A) polymerase
chr17_+_24597001 2.61 ENSDART00000191834
rearranged L-myc fusion
chr5_-_26247973 2.58 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr23_+_42272588 2.55 ENSDART00000164907

chr20_-_49889111 2.53 ENSDART00000058858
kinesin family member 13Bb
chr14_+_50937757 2.53 ENSDART00000163865
ring finger protein 44
chr2_-_37103622 2.49 ENSDART00000137849
zgc:101744
chr2_-_32387441 2.41 ENSDART00000148202
upstream binding transcription factor, like
chr16_+_11779761 2.41 ENSDART00000140297
si:dkey-250k15.4
chr2_+_3516913 2.40 ENSDART00000109346

chr2_-_1486023 2.40 ENSDART00000113774
si:ch211-188c16.1
chr22_-_38258053 2.38 ENSDART00000132516
ELAV like neuron-specific RNA binding protein 2
chr16_+_15114645 2.35 ENSDART00000158483
MDM2 binding protein
chr21_+_3960583 2.35 ENSDART00000149788
senataxin
chr5_-_26247671 2.34 ENSDART00000145187
endoplasmic reticulum aminopeptidase 1b
chr24_-_41797681 2.33 ENSDART00000169643
Rho GTPase activating protein 28
chr20_+_35438300 2.32 ENSDART00000102504
ENSDART00000153249
tudor domain containing 6
chr16_-_34195002 2.31 ENSDART00000054026
regulator of chromosome condensation 1
chr2_-_17115256 2.30 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr9_+_54237100 2.28 ENSDART00000148928
RNA binding motif protein 27
chr1_+_44173506 2.25 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr6_+_11760749 2.24 ENSDART00000112212
zinc finger, SWIM-type containing 2
chr25_-_7918526 2.24 ENSDART00000104686
ENSDART00000156761
autophagy/beclin-1 regulator 1b
chr4_-_9350585 2.22 ENSDART00000148155
si:ch211-125a15.1
chr7_-_16194952 2.20 ENSDART00000173739
bloodthirsty-related gene family, member 4
chr14_+_21755469 2.19 ENSDART00000186326
lysine (K)-specific demethylase 2Ab
chr23_+_39854566 2.17 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr19_-_874888 2.16 ENSDART00000007206
eomesodermin homolog a
chr13_-_35908275 2.13 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr17_-_31819837 2.09 ENSDART00000160281
abraxas 2b, BRISC complex subunit
chr19_-_10330778 2.06 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
coiled-coil domain containing 106b
chr6_+_19948043 2.06 ENSDART00000182636
phosphoinositide-3-kinase, regulatory subunit 5
chr11_+_25583950 2.05 ENSDART00000111961
coiled-coil domain containing 120
chr22_-_9896180 2.00 ENSDART00000138343
zinc finger protein 990
chr16_+_20055878 2.00 ENSDART00000146436
ankyrin repeat domain 28b
chr4_+_15006217 1.99 ENSDART00000090837
zinc finger, C3HC-type containing 1
chr10_-_25543227 1.98 ENSDART00000007778
glutamate receptor, ionotropic, kainate 1a
chr1_-_24349759 1.98 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr16_+_26732086 1.98 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr13_+_22717939 1.94 ENSDART00000188288
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr8_+_3431671 1.94 ENSDART00000017850
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr5_+_45139196 1.93 ENSDART00000113738
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_15444210 1.92 ENSDART00000142509
lin-28 homolog A (C. elegans)
chr14_+_26247319 1.89 ENSDART00000192793
coiled-coil domain containing 69
chr2_-_16449504 1.88 ENSDART00000144801
ATR serine/threonine kinase
chr13_-_35808904 1.87 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr10_+_44719697 1.87 ENSDART00000158087
scavenger receptor class B, member 1
chr10_-_31016806 1.87 ENSDART00000027288
pannexin 3
chr2_+_27386617 1.86 ENSDART00000134976
si:ch73-382f3.1
chr10_+_34001444 1.83 ENSDART00000149934
klotho
chr7_+_5956937 1.82 ENSDART00000170763
histone cluster 1 H2A family member 4
chr13_-_35907768 1.82 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr7_+_24081167 1.79 ENSDART00000141749
apoptotic chromatin condensation inducer 1b
chr3_+_27642081 1.78 ENSDART00000055500
pentraxin 4, long
chr10_-_35257458 1.76 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr16_+_20056030 1.73 ENSDART00000027020
ankyrin repeat domain 28b
chr13_+_46718518 1.73 ENSDART00000160401
ENSDART00000182884
transmembrane protein 63Ba
chr1_+_19433004 1.72 ENSDART00000133959
clock circadian regulator b
chr7_+_24573721 1.71 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr20_-_32148901 1.69 ENSDART00000153405
ENSDART00000048537
ENSDART00000152984
centrosomal protein 57, like 1
chr1_+_52481332 1.69 ENSDART00000074231
claudin domain containing 1b
chr15_-_30857350 1.64 ENSDART00000138988
A kinase (PRKA) anchor protein 1b
chr7_+_34236238 1.62 ENSDART00000052474
timeless interacting protein
chr3_-_52683241 1.61 ENSDART00000155248
si:dkey-210j14.5
chr25_+_15938880 1.61 ENSDART00000089035
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr13_+_7387822 1.60 ENSDART00000148240
exocyst complex component 3-like 4
chr5_+_57480014 1.60 ENSDART00000135520
si:ch211-202f5.3
chr21_-_25801956 1.60 ENSDART00000101219
methyltransferase like 27
chr3_+_35005730 1.58 ENSDART00000029451
protein kinase C, beta b
chr16_+_9400661 1.58 ENSDART00000146174
KIAA0947-like (H. sapiens)
chr17_+_30591287 1.58 ENSDART00000154243
si:dkey-190l8.2
chr5_+_20255568 1.58 ENSDART00000153643
slingshot protein phosphatase 1a
chr3_+_22036113 1.57 ENSDART00000132190
cell division cycle 27
chr20_-_3310017 1.56 ENSDART00000099315
CCAAT/enhancer binding protein (C/EBP), zeta
chr17_-_17759138 1.55 ENSDART00000157128
ENSDART00000123845
aarF domain containing kinase 1
chr25_-_20666328 1.55 ENSDART00000098076
C-terminal Src kinase
chr7_+_38260434 1.51 ENSDART00000052351
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr7_-_24644893 1.50 ENSDART00000048921
GP1 homolog, RAB6A GEF complex partner 1
chr3_+_22035863 1.50 ENSDART00000177169
cell division cycle 27
chr17_+_21760032 1.50 ENSDART00000190425
IKAROS family zinc finger 5
chr19_-_3488860 1.49 ENSDART00000172520
human immunodeficiency virus type I enhancer binding protein 1
chr5_-_57879138 1.49 ENSDART00000145959
salt-inducible kinase 2a
chr7_-_40630698 1.48 ENSDART00000134547
ubiquitin protein ligase E3C
chr2_+_49457449 1.48 ENSDART00000185470
SH3-domain GRB2-like 1a
chr3_+_31093455 1.48 ENSDART00000153074
si:dkey-66i24.9
chr12_+_30368145 1.47 ENSDART00000153454
si:ch211-225b10.4
chr9_+_8968702 1.45 ENSDART00000008490
ubiquitin conjugating enzyme E2 A, like
chr12_+_18906939 1.44 ENSDART00000186074
Josephin domain containing 1
chr18_-_38271298 1.42 ENSDART00000143016
cell cycle associated protein 1b
chr17_+_7534180 1.42 ENSDART00000187512
SNF2 histone linker PHD RING helicase
chr19_+_24891747 1.40 ENSDART00000132209
ENSDART00000193610
EYA transcriptional coactivator and phosphatase 3
chr9_+_500052 1.40 ENSDART00000166707

chr5_-_23783739 1.39 ENSDART00000139502
si:ch211-287c22.1
chr3_+_43373867 1.38 ENSDART00000159455
ENSDART00000172425
zinc finger, AN1-type domain 2A
chr2_-_38080075 1.37 ENSDART00000056544
TOX high mobility group box family member 4 a
chr4_-_12477224 1.37 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr5_+_24087035 1.36 ENSDART00000183644
tumor protein p53
chr15_-_41689684 1.36 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr17_+_22311413 1.35 ENSDART00000151929
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr11_-_25461336 1.35 ENSDART00000014945
host cell factor C1a
chr13_+_9612395 1.35 ENSDART00000136689
ENSDART00000138362
SMC5-SMC6 complex localization factor 2
chr21_+_25801345 1.33 ENSDART00000035062
neurofibromin 2b (merlin)
chr23_-_24955135 1.33 ENSDART00000136347
ENSDART00000144903
zinc finger and BTB domain containing 48
chr5_+_45138934 1.33 ENSDART00000041412
ENSDART00000136002
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_38314466 1.33 ENSDART00000048753
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr18_-_43884044 1.32 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr16_+_53387085 1.32 ENSDART00000154223
ENSDART00000101404
kinesin family member 13A
chr7_+_36467796 1.32 ENSDART00000146202
akt interacting protein
chr24_+_24726956 1.32 ENSDART00000144574
ENSDART00000066628
mitochondrial fission regulator 1
chr25_-_3745393 1.32 ENSDART00000037973
MORC family CW-type zinc finger 2
chr1_+_29267841 1.31 ENSDART00000085648
ligase IV, DNA, ATP-dependent
chr6_+_3473657 1.31 ENSDART00000011785
RAD54 like
chr2_-_32826108 1.30 ENSDART00000098834
pre-mRNA processing factor 4Ba
chr17_+_7534365 1.29 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr13_+_15701849 1.28 ENSDART00000003517
tRNA methyltransferase 61A
chr5_+_52596850 1.27 ENSDART00000162022
protein prenyltransferase alpha subunit repeat containing 1
chr3_+_32714157 1.27 ENSDART00000131774
SET domain containing 1A
chr3_+_22443313 1.26 ENSDART00000156450
WNK lysine deficient protein kinase 4b
chr16_+_25285998 1.25 ENSDART00000154112
si:dkey-29h14.10
chr2_-_32825917 1.24 ENSDART00000180409
pre-mRNA processing factor 4Ba
chr7_+_24645186 1.24 ENSDART00000150118
ENSDART00000150233
ENSDART00000087691
glucosidase, beta (bile acid) 2
chr2_-_40890004 1.24 ENSDART00000191746
UDP-glucose glycoprotein glucosyltransferase 1
chr12_+_18906407 1.23 ENSDART00000105854
Josephin domain containing 1
chr20_-_32405440 1.23 ENSDART00000062978
ENSDART00000153411
AFG1 like ATPase b
chr12_+_13742778 1.22 ENSDART00000111401
ENSDART00000190552
protein phosphatase 1, regulatory subunit 16A
chr23_-_31913231 1.21 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr2_+_45100963 1.21 ENSDART00000160122

chr3_-_61387273 1.20 ENSDART00000156479
zinc finger protein 1143
chr13_+_15656042 1.20 ENSDART00000134240
MAP/microtubule affinity-regulating kinase 3a
chr5_+_7279104 1.20 ENSDART00000190014
si:ch73-72b7.1
chr13_-_33227411 1.19 ENSDART00000057386
golgin A5
chr1_-_55131439 1.18 ENSDART00000074083
RAB1A, member RAS oncogene family a
chr8_+_36560019 1.18 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
splicing factor 3a, subunit 1
chr2_-_40889465 1.18 ENSDART00000192631
ENSDART00000180824
UDP-glucose glycoprotein glucosyltransferase 1
chr5_+_61944453 1.18 ENSDART00000134344
si:dkeyp-117b8.4
chr22_-_10055744 1.18 ENSDART00000143686
si:ch211-222k6.2
chr19_-_6083761 1.18 ENSDART00000151185
ENSDART00000143941
glycogen synthase kinase 3 alpha a
chr15_-_14193926 1.17 ENSDART00000162707
polynucleotide kinase 3'-phosphatase
chr5_+_32141790 1.17 ENSDART00000041504
tescalcin b
chr16_+_29376751 1.17 ENSDART00000168856
ENSDART00000162502
ENSDART00000050535
ribosomal RNA adenine dimethylase domain containing 1
chr17_+_8754020 1.16 ENSDART00000105322
erythroid differentiation regulatory factor 1
chr20_-_38827623 1.16 ENSDART00000153310
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr23_-_36884012 1.15 ENSDART00000137282
ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)
chr3_+_3519607 1.14 ENSDART00000150922
CDC42 effector protein (Rho GTPase binding) 1b
chr18_+_7639401 1.14 ENSDART00000092416
RAB, member of RAS oncogene family-like 2
chr4_-_18840487 1.14 ENSDART00000066978
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr11_-_16394971 1.14 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr17_+_21817382 1.14 ENSDART00000079011
ENSDART00000189387
IKAROS family zinc finger 5
chr2_-_41571454 1.13 ENSDART00000022643
zinc finger protein 622
chr23_+_17509794 1.13 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr9_-_21488976 1.13 ENSDART00000080404
M-phase phosphoprotein 8
chr5_+_8196264 1.12 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr15_-_30853246 1.12 ENSDART00000112511
A kinase (PRKA) anchor protein 1b
chr7_+_25000060 1.12 ENSDART00000039265
ENSDART00000141814
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr10_+_36345176 1.11 ENSDART00000099397
odorant receptor, family C, subfamily 105, member 1
chr25_-_24202576 1.11 ENSDART00000048507
UEV and lactate/malate dehyrogenase domains
chr11_-_34232906 1.10 ENSDART00000162150
large 60S subunit nuclear export GTPase 1
chr7_+_65398161 1.10 ENSDART00000166109
ENSDART00000157399
ubiquitin specific peptidase 47
chr5_-_37997774 1.09 ENSDART00000139616
ENSDART00000167694
si:dkey-111e8.1
chr23_-_35790235 1.08 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
major facilitator superfamily domain containing 5
chr12_+_14149686 1.08 ENSDART00000123741
kelch repeat and BTB (POZ) domain containing 2
chr17_+_8754426 1.08 ENSDART00000185519
erythroid differentiation regulatory factor 1
chr4_-_75172216 1.08 ENSDART00000127522
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr19_-_11315224 1.08 ENSDART00000104933
endonuclease/exonuclease/phosphatase family domain containing 1
chr7_-_41512999 1.08 ENSDART00000173577
si:dkey-10f23.2
chr25_-_24247584 1.08 ENSDART00000046349
SPT2 chromatin protein domain containing 1
chr4_+_73051901 1.07 ENSDART00000174219
zgc:152938
chr2_+_32826235 1.07 ENSDART00000143127
si:dkey-154p10.3
chr17_+_24446353 1.07 ENSDART00000140467
UDP-glucose pyrophosphorylase 2b
chr17_+_50657509 1.06 ENSDART00000179957
DDHD domain containing 1a
chr7_+_32901658 1.05 ENSDART00000115420
anoctamin 9b
chr12_-_48467733 1.05 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
SEC31 homolog B, COPII coat complex component
chr13_-_10727550 1.04 ENSDART00000190925
protein phosphatase, Mg2+/Mn2+ dependent, 1Ba
chr21_+_3897680 1.04 ENSDART00000170653
dolichyldiphosphatase 1
chr23_+_24954951 1.04 ENSDART00000136941
nucleolar protein 9
chr1_+_26105141 1.04 ENSDART00000102379
ENSDART00000127154
topoisomerase I binding, arginine/serine-rich a
chr13_+_9896368 1.03 ENSDART00000137388
si:ch211-117n7.8
chr15_+_24756860 1.03 ENSDART00000156424
ENSDART00000078035
carboxypeptidase D, a
chr7_-_18712482 1.03 ENSDART00000173517
ENSDART00000122564
ENSDART00000173905
tRNA methyltransferase 10A
chr3_+_7040363 1.03 ENSDART00000157805

chr3_-_7546740 1.02 ENSDART00000128960
zmp:0000001003
chr11_+_25693395 1.02 ENSDART00000110224
MON1 secretory trafficking family member Bb
chr6_-_51771634 1.02 ENSDART00000073847
bladder cancer associated protein
chr6_+_42475730 1.02 ENSDART00000150226
macrophage stimulating 1 receptor a
chr10_+_2582254 1.02 ENSDART00000016103
nucleoredoxin like 2
chr5_-_56943064 1.01 ENSDART00000146991
si:ch211-127d4.3

Network of associatons between targets according to the STRING database.

First level regulatory network of barhl1a+barhl1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.6 1.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 3.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.5 2.7 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.5 2.6 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.5 2.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.5 1.4 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.4 4.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 1.2 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.4 1.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.4 1.9 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.4 1.2 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.4 3.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.4 1.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.3 2.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 2.3 GO:0030719 P granule organization(GO:0030719)
0.3 2.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.3 1.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 3.9 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.3 1.9 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.3 1.6 GO:0043111 replication fork arrest(GO:0043111)
0.3 3.5 GO:0045453 bone resorption(GO:0045453)
0.3 1.5 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.3 1.5 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 0.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.3 0.9 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.3 3.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 1.9 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 0.7 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 2.3 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 3.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 3.7 GO:0016926 protein desumoylation(GO:0016926)
0.2 1.9 GO:0032196 transposition(GO:0032196)
0.2 0.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 2.1 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.2 0.6 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 3.2 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.2 6.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.2 1.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.2 2.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 2.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 1.7 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.2 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 1.3 GO:0034063 stress granule assembly(GO:0034063)
0.2 1.6 GO:0051601 exocyst localization(GO:0051601)
0.2 2.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 2.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.2 1.4 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 0.6 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 0.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.5 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.8 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.3 GO:0051098 regulation of binding(GO:0051098)
0.1 1.1 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.6 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 2.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 2.6 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.3 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 1.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 1.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 3.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 2.4 GO:0009648 photoperiodism(GO:0009648)
0.1 0.7 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 2.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.4 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.9 GO:0045005 replication fork processing(GO:0031297) DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.1 2.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 2.4 GO:0016574 histone ubiquitination(GO:0016574)
0.1 2.2 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 1.9 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.2 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.3 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.4 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 7.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.0 2.0 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.9 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 1.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 1.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.2 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.9 GO:0060173 limb development(GO:0060173)
0.0 2.8 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 1.5 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 1.6 GO:0050852 antigen receptor-mediated signaling pathway(GO:0050851) T cell receptor signaling pathway(GO:0050852)
0.0 0.7 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 1.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 4.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 4.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 2.1 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 1.4 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) embryonic skeletal joint development(GO:0072498)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 2.0 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 0.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.3 GO:0016064 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958) immunoglobulin mediated immune response(GO:0016064) B cell mediated immunity(GO:0019724)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 1.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.1 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.0 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 1.5 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0071514 genetic imprinting(GO:0071514)
0.0 1.2 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.8 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 1.6 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.7 GO:0072665 protein localization to vacuole(GO:0072665)
0.0 0.1 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 1.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.2 GO:0003341 cilium movement(GO:0003341)
0.0 1.7 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.7 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.3 GO:0042476 odontogenesis(GO:0042476)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0033391 chromatoid body(GO:0033391)
0.5 3.7 GO:0071546 pi-body(GO:0071546)
0.5 2.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.4 1.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4 1.2 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.3 1.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 1.6 GO:0031298 replication fork protection complex(GO:0031298)
0.3 1.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 1.5 GO:0033503 HULC complex(GO:0033503)
0.3 0.8 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.3 1.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 1.3 GO:0070695 FHF complex(GO:0070695)
0.2 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 4.0 GO:0043186 P granule(GO:0043186)
0.2 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 4.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 2.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 2.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.0 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.8 GO:0001650 fibrillar center(GO:0001650)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 3.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.0 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.9 GO:0035101 FACT complex(GO:0035101)
0.1 2.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.9 GO:0005921 gap junction(GO:0005921)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.1 GO:0015030 Cajal body(GO:0015030)
0.1 2.5 GO:0005657 replication fork(GO:0005657)
0.1 1.6 GO:0000145 exocyst(GO:0000145)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 3.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 3.9 GO:0005871 kinesin complex(GO:0005871)
0.0 1.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.6 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 3.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 2.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.3 GO:0016604 nuclear body(GO:0016604)
0.0 1.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.2 GO:0042383 sarcolemma(GO:0042383)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0005930 axoneme(GO:0005930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.7 3.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.7 2.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.7 2.0 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.5 2.2 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.5 3.3 GO:0015616 DNA translocase activity(GO:0015616)
0.5 2.7 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 2.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.5 2.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 3.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.4 1.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.4 1.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.4 1.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 1.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.2 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.3 0.8 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.3 1.8 GO:0070888 E-box binding(GO:0070888)
0.3 3.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 1.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.2 1.0 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 3.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 1.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.6 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 1.7 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 0.9 GO:0043295 glutathione binding(GO:0043295)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.5 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.2 0.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 4.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 2.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.9 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 1.8 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 4.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 1.9 GO:0022829 wide pore channel activity(GO:0022829)
0.1 5.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.7 GO:0000049 tRNA binding(GO:0000049)
0.1 2.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.5 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 2.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 3.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.4 GO:0017108 RNA-DNA hybrid ribonuclease activity(GO:0004523) 5'-flap endonuclease activity(GO:0017108)
0.1 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.4 GO:0022839 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 4.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.0 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 19.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 6.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 3.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.8 GO:0008238 exopeptidase activity(GO:0008238)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 1.9 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 5.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.3 2.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 4.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 3.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 1.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.1 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway