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PRJNA195909:zebrafish embryo and larva development

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Results for arxa

Z-value: 0.89

Motif logo

Transcription factors associated with arxa

Gene Symbol Gene ID Gene Info
ENSDARG00000058011 aristaless related homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arxadr11_v1_chr24_-_23942722_23942722-0.826.7e-03Click!

Activity profile of arxa motif

Sorted Z-values of arxa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_53044300 2.21 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr25_+_22320738 2.00 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr2_-_38284648 1.58 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
chr2_-_26596794 1.55 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr18_-_40708537 1.49 ENSDART00000077577
si:ch211-132b12.8
chr1_+_35985813 1.47 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr5_+_37903790 1.43 ENSDART00000162470
transmembrane protease, serine 4b
chr7_-_24520866 1.43 ENSDART00000077039
fatty acid amide hydrolase 2b
chr14_-_7045009 1.16 ENSDART00000112082
RUN and FYVE domain containing 1
chr21_-_44081540 1.13 ENSDART00000130833

chr25_-_21031007 1.12 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr12_-_33357655 1.09 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr14_+_34558480 1.07 ENSDART00000075170
pituitary tumor-transforming 1
chr25_-_1323623 1.06 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calmodulin-like 4b
chr4_+_11723852 1.05 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr11_-_39118882 1.05 ENSDART00000113185
ENSDART00000156526
adaptor-related protein complex 5, beta 1 subunit
chr22_+_23359369 1.04 ENSDART00000170886
DENN/MADD domain containing 1B
chr19_+_2631565 1.04 ENSDART00000171487
family with sequence similarity 126, member A
chr14_-_33481428 1.02 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lysosomal-associated membrane protein 2
chr6_+_40922572 0.98 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr20_-_37813863 0.98 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr11_+_11152214 0.96 ENSDART00000148030
lymphocyte antigen 75
chr21_-_30082414 0.94 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr17_+_50076501 0.93 ENSDART00000156303
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr5_-_16472719 0.92 ENSDART00000162071
piwi-like RNA-mediated gene silencing 2
chr3_+_7808459 0.89 ENSDART00000162374
hook microtubule-tethering protein 2
chr23_+_1029450 0.88 ENSDART00000189196
si:zfos-905g2.1
chr9_+_45493341 0.87 ENSDART00000145616
adenosine deaminase, RNA-specific, B1b
chr14_-_48765262 0.87 ENSDART00000166463
CCR4-NOT transcription complex, subunit 6b
chr24_-_29586082 0.87 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr18_+_35128685 0.86 ENSDART00000151579
si:ch211-195m9.3
chr14_-_14659023 0.86 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr6_+_12527725 0.85 ENSDART00000149328
serine/threonine kinase 24b (STE20 homolog, yeast)
chr13_-_31017960 0.84 ENSDART00000145287
WDFY family member 4
chr8_-_39822917 0.84 ENSDART00000067843
zgc:162025
chr2_+_35806672 0.81 ENSDART00000137384
RAS protein activator like 2
chr2_+_10878406 0.79 ENSDART00000091497
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr20_-_51831816 0.78 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr8_-_51930826 0.77 ENSDART00000109785
calcineurin binding protein 1
chr16_-_31622777 0.76 ENSDART00000137311
ENSDART00000002930
PHD finger protein 20 like 1
chr13_-_35808904 0.75 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr23_-_19225709 0.74 ENSDART00000080099
O-acyl-ADP-ribose deacylase 1
chr21_+_13387965 0.74 ENSDART00000134347
zgc:113162
chr17_-_40956035 0.74 ENSDART00000124715
si:dkey-16j16.4
chr6_-_55399214 0.74 ENSDART00000168367
cathepsin A
chr21_+_43172506 0.73 ENSDART00000121725
zinc finger, CCHC domain containing 10
chr10_-_2788668 0.68 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr20_+_29209767 0.68 ENSDART00000141252
katanin p80 subunit B-like 1
chr23_+_4709607 0.67 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr21_-_2814709 0.67 ENSDART00000097664
semaphorin 4D
chr18_+_39106722 0.65 ENSDART00000122377
BCL2 like 10
chr3_-_59297532 0.65 ENSDART00000187991

chr25_+_30131055 0.65 ENSDART00000152705
apoptosis inhibitor 5
chr2_+_56657804 0.65 ENSDART00000113964
RNA polymerase II subunit E
chr21_+_21195487 0.65 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr6_+_36839509 0.65 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr7_+_24573721 0.65 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr12_-_48188928 0.65 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr7_-_51727760 0.64 ENSDART00000174180
histone deacetylase 8
chr14_+_14806692 0.64 ENSDART00000193050
FH2 domain containing 2
chr16_+_19029297 0.64 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr20_-_40360571 0.63 ENSDART00000144768
sphingomyelin phosphodiesterase, acid-like 3A
chr16_-_54971277 0.63 ENSDART00000113358
WD and tetratricopeptide repeats 1
chr2_-_17393216 0.62 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr21_+_6394929 0.61 ENSDART00000138600
si:ch211-225g23.1
chr2_-_17392799 0.61 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr20_+_20731633 0.60 ENSDART00000191952
ENSDART00000165224
protein phosphatase 1, regulatory subunit 13Bb
chr9_-_34937025 0.60 ENSDART00000137888
cell division cycle 16 homolog (S. cerevisiae)
chr13_+_15656042 0.60 ENSDART00000134240
MAP/microtubule affinity-regulating kinase 3a
chr20_+_20731052 0.60 ENSDART00000047662
protein phosphatase 1, regulatory subunit 13Bb
chr21_-_45363871 0.60 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
zgc:56064
chr19_+_1688727 0.59 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr1_+_47499888 0.59 ENSDART00000027624
STN1, CST complex subunit
chr2_-_9989919 0.59 ENSDART00000180213
ENSDART00000184369
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr4_+_2482046 0.59 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr16_-_7793457 0.59 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr15_-_38129845 0.58 ENSDART00000057095
si:dkey-24p1.1
chr7_+_6941583 0.58 ENSDART00000160709
ENSDART00000157634
RNA binding motif protein 14b
chr20_+_29209926 0.58 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr13_+_38817871 0.57 ENSDART00000187708
collagen, type XIX, alpha 1
chr1_-_45616470 0.57 ENSDART00000150165
activating transcription factor 7 interacting protein
chr9_+_29643036 0.56 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr5_-_11809710 0.55 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr11_-_44979281 0.55 ENSDART00000190972
LIM-domain binding 1b
chr20_+_22799857 0.55 ENSDART00000058527
sec1 family domain containing 2
chr11_+_31324335 0.54 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr2_-_10877765 0.53 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr20_+_29209615 0.53 ENSDART00000062350
katanin p80 subunit B-like 1
chr2_+_1988036 0.52 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr9_+_24065855 0.52 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr1_+_27977297 0.51 ENSDART00000180692
ENSDART00000166819
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr7_-_5375214 0.50 ENSDART00000033316
VANGL planar cell polarity protein 2
chr1_+_19433004 0.50 ENSDART00000133959
clock circadian regulator b
chr4_-_3353595 0.49 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr3_-_26787430 0.49 ENSDART00000087047
RAB40c, member RAS oncogene family
chr2_+_9990491 0.48 ENSDART00000011906
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr22_-_16443199 0.47 ENSDART00000006290
ENSDART00000193335
pleckstrin homology domain containing, family B (evectins) member 2
chr21_+_43328685 0.47 ENSDART00000109620
ENSDART00000139668
septin 8a
chr1_+_47165842 0.47 ENSDART00000053152
ENSDART00000167051
carbonyl reductase 1
chr24_+_29912509 0.46 ENSDART00000168422
ferric-chelate reductase 1b
chr12_+_47698356 0.46 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr9_-_9415000 0.46 ENSDART00000146210
si:ch211-214p13.9
chr22_-_20812822 0.46 ENSDART00000193778
DOT1-like histone H3K79 methyltransferase
chr13_+_4409294 0.46 ENSDART00000146437
si:ch211-130h14.4
chr20_-_43663494 0.45 ENSDART00000144564

chr23_-_36303216 0.44 ENSDART00000188720
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr11_+_31323746 0.44 ENSDART00000180220
ENSDART00000189937
signal-induced proliferation-associated 1 like 2
chr13_-_36798204 0.43 ENSDART00000012357
salvador family WW domain containing protein 1
chr18_+_13275735 0.43 ENSDART00000148127
phospholipase C, gamma 2
chr14_-_470505 0.43 ENSDART00000067147
ankyrin repeat domain 50
chr6_-_40922971 0.42 ENSDART00000155363
SFI1 centrin binding protein
chr5_+_32076109 0.41 ENSDART00000051357
ENSDART00000144510
zinc finger, matrin-type 5
chr16_-_31351419 0.41 ENSDART00000178298
ENSDART00000018091
maestro heat-like repeat family member 1
chr25_+_7241084 0.40 ENSDART00000190501
ENSDART00000190588
high mobility group 20A
chr22_+_30137374 0.40 ENSDART00000187808
adducin 3 (gamma) a
chr8_+_49065348 0.40 ENSDART00000032277
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr18_-_14274803 0.40 ENSDART00000166643
malonyl-CoA decarboxylase
chr20_+_38458084 0.39 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr4_-_5108844 0.38 ENSDART00000132666
ENSDART00000136096
transmembrane protein 209
chr16_-_28658341 0.38 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr11_+_45436703 0.38 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr4_-_1801519 0.38 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr9_-_11676491 0.37 ENSDART00000022358
zinc finger CCCH-type containing 15
chr10_+_34010494 0.37 ENSDART00000186836
ENSDART00000114703
klotho
chr5_+_69747417 0.36 ENSDART00000153717
si:ch211-275j6.5
chr24_-_18809433 0.35 ENSDART00000152009
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr4_-_2975461 0.35 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr25_-_27621268 0.35 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr16_+_23799622 0.34 ENSDART00000046922
RAB13, member RAS oncogene family
chr13_-_14487524 0.33 ENSDART00000141103
GDNF family receptor alpha 4a
chr7_-_8712148 0.33 ENSDART00000065488
testis expressed 261
chr22_+_737211 0.33 ENSDART00000017305
zinc finger protein 76
chr21_-_15200556 0.32 ENSDART00000141809
splicing factor SWAP
chr8_+_7801060 0.32 ENSDART00000161618
transcription factor binding to IGHM enhancer 3a
chr7_-_7692723 0.31 ENSDART00000183352
aminoadipate aminotransferase
chr24_+_19415124 0.30 ENSDART00000186931
sulfatase 1
chr2_-_1622641 0.30 ENSDART00000082143
protein kinase, cAMP-dependent, catalytic, beta b
chr14_-_41388178 0.30 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr13_+_12761707 0.29 ENSDART00000015127
zgc:100846
chr23_+_29885019 0.29 ENSDART00000167059
aurora kinase A interacting protein 1
chr10_+_26652859 0.29 ENSDART00000079174
HIV-1 Tat specific factor 1
chr18_-_43884044 0.29 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr7_-_51368681 0.29 ENSDART00000146385
Rho GTPase activating protein 36
chr25_-_10791437 0.28 ENSDART00000127054

chr3_+_40164129 0.28 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr22_-_14739491 0.27 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr23_+_36460239 0.26 ENSDART00000172441
LIM domain and actin binding 1a
chr2_-_55298075 0.26 ENSDART00000186404
ENSDART00000149062
RAB8A, member RAS oncogene family
chr16_+_54209504 0.24 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr21_-_33995710 0.24 ENSDART00000100508
ENSDART00000179622
early B cell factor 1b
chr3_+_431208 0.24 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
chr16_-_13818061 0.24 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr17_-_16422654 0.23 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr16_-_30434279 0.22 ENSDART00000018504
zgc:77086
chr17_-_9950911 0.22 ENSDART00000105117
serine palmitoyltransferase, small subunit A
chr17_+_15983557 0.22 ENSDART00000190806
calmin
chr17_+_20589553 0.22 ENSDART00000154447
si:ch73-288o11.4
chr9_+_54039006 0.22 ENSDART00000112441
toll-like receptor 7
chr5_+_66433287 0.22 ENSDART00000170757
kinetochore associated 1
chr10_-_11261565 0.22 ENSDART00000146727
polypyrimidine tract binding protein 3
chr20_+_22799641 0.21 ENSDART00000131132
sec1 family domain containing 2
chr5_+_24156170 0.21 ENSDART00000136570
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr10_-_11261386 0.20 ENSDART00000189946
polypyrimidine tract binding protein 3
chr10_-_3138859 0.20 ENSDART00000190606
ubiquitin-conjugating enzyme E2L 3a
chr16_+_13818743 0.19 ENSDART00000090191
folliculin
chr4_-_5019113 0.19 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr15_-_2754056 0.19 ENSDART00000129380
protein phosphatase 5, catalytic subunit
chr2_+_2169337 0.19 ENSDART00000179939
HIG1 hypoxia inducible domain family, member 1A
chr7_-_7692992 0.19 ENSDART00000192619
aminoadipate aminotransferase
chr13_-_12602920 0.19 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr10_-_3138403 0.19 ENSDART00000183365
ubiquitin-conjugating enzyme E2L 3a
chr20_+_25586099 0.18 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr15_-_35098345 0.18 ENSDART00000181824

chr22_-_5252005 0.18 ENSDART00000132942
ENSDART00000081801
nicalin
chr7_+_21272833 0.18 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr20_-_29864390 0.17 ENSDART00000161834
ENSDART00000132278
ring finger protein 144ab
chr17_+_44697604 0.17 ENSDART00000156625
placental growth factor b
chr14_+_10954345 0.17 ENSDART00000106658
zinc finger, DHHC-type containing 15b
chr9_-_43538328 0.17 ENSDART00000140526
zinc finger protein 385B
chr3_+_32118670 0.16 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr6_+_8598428 0.16 ENSDART00000032118
ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
chr22_-_36530902 0.14 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr7_+_24023653 0.13 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr21_-_4793686 0.13 ENSDART00000158232
notch 1a
chr7_+_7019911 0.13 ENSDART00000172421
RNA binding motif protein 14b
chr21_+_45223194 0.13 ENSDART00000150902
si:ch73-269m14.3
chr17_+_3379673 0.13 ENSDART00000176354
syntrophin, gamma 2
chr9_-_30555725 0.12 ENSDART00000079222
chromatin assembly factor 1, subunit B
chr13_+_646700 0.12 ENSDART00000006892
tumor protein p53 binding protein, 2a
chr6_+_49551614 0.12 ENSDART00000022581
RAB22A, member RAS oncogene family
chr25_-_13490744 0.12 ENSDART00000056721
lactate dehydrogenase D
chr14_+_40874608 0.12 ENSDART00000168448
si:ch211-106m9.1
chr19_+_5480327 0.11 ENSDART00000148794
junction plakoglobin b
chr10_+_11261576 0.09 ENSDART00000155333
hydroxysteroid dehydrogenase like 2
chr23_+_12134839 0.09 ENSDART00000128551
ENSDART00000141204
tubulin tyrosine ligase-like family, member 9
chr5_+_66312359 0.08 ENSDART00000137534
MALT paracaspase 1
chr15_+_34592215 0.08 ENSDART00000099776
tetraspanin 13a
chr1_+_23161369 0.08 ENSDART00000162827
si:dkey-92j12.5
chr16_-_32837806 0.08 ENSDART00000003997
si:dkey-165n16.5
chr7_+_34453185 0.08 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1

Network of associatons between targets according to the STRING database.

First level regulatory network of arxa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.6 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.8 GO:0097065 anterior head development(GO:0097065)
0.1 0.6 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.5 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.6 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 1.6 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.4 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.2 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.7 GO:0051279 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.1 0.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.1 GO:2000816 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.8 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.7 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.9 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.9 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0050821 protein stabilization(GO:0050821)
0.0 0.4 GO:0006415 translational termination(GO:0006415)
0.0 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.3 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 1.2 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.0 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.0 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.6 GO:1990879 CST complex(GO:1990879)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.9 GO:1990923 PET complex(GO:1990923)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.0 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.9 GO:0034584 piRNA binding(GO:0034584)
0.1 0.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.3 GO:0002039 p53 binding(GO:0002039)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.6 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.5 GO:0004527 exonuclease activity(GO:0004527)
0.0 2.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+