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PRJNA195909:zebrafish embryo and larva development
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Results for arnt2
Z-value: 2.64
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Transcription factors associated with arnt2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| arnt2 | dr11_v1_chr7_+_10701770_10701770 | 0.44 | 2.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_74090168 Show fit | 6.59 |
ENSDART00000050528
|
tyrosinase-related protein 1a |
|
| chr14_+_46313135 Show fit | 5.63 |
ENSDART00000172902
|
crystallin, beta A1, like 1 |
|
| chr14_+_46313396 Show fit | 4.95 |
ENSDART00000047525
|
crystallin, beta A1, like 1 |
|
| chr9_-_44295071 Show fit | 4.56 |
ENSDART00000011837
|
neuronal differentiation 1 |
|
| chr7_+_49715750 Show fit | 4.33 |
ENSDART00000019446
|
achaete-scute family bHLH transcription factor 1b |
|
| chr21_+_6751405 Show fit | 4.19 |
ENSDART00000037265
ENSDART00000146371 |
olfactomedin 1b |
|
| chr21_+_6751760 Show fit | 4.15 |
ENSDART00000135914
|
olfactomedin 1b |
|
| chr23_-_6641223 Show fit | 3.20 |
ENSDART00000023793
|
major intrinsic protein of lens fiber b |
|
| chr18_-_23875219 Show fit | 2.70 |
ENSDART00000059976
|
nuclear receptor subfamily 2, group F, member 2 |
|
| chr17_-_25326296 Show fit | 2.66 |
ENSDART00000168822
|
poly(A) binding protein, cytoplasmic 4 (inducible form) |
Network of associatons between targets according to the STRING database.
First level regulatory network of arnt2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.6 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.7 | 6.6 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
| 2.1 | 6.4 | GO:0060843 | lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845) |
| 0.3 | 5.5 | GO:0048923 | posterior lateral line neuromast hair cell differentiation(GO:0048923) |
| 0.1 | 4.8 | GO:0021575 | hindbrain morphogenesis(GO:0021575) |
| 0.1 | 3.7 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 3.3 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.5 | 3.2 | GO:0006833 | water transport(GO:0006833) |
| 0.2 | 3.0 | GO:0033173 | calcineurin-NFAT signaling cascade(GO:0033173) |
| 0.1 | 2.9 | GO:0032526 | response to retinoic acid(GO:0032526) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 27.7 | GO:0005576 | extracellular region(GO:0005576) |
| 0.5 | 6.6 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 4.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.5 | 3.6 | GO:0071914 | prominosome(GO:0071914) |
| 0.0 | 3.6 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 3.4 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 3.0 | GO:0030424 | axon(GO:0030424) |
| 0.5 | 2.8 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 2.6 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 2.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 31.3 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 18.0 | GO:0046983 | protein dimerization activity(GO:0046983) |
| 0.1 | 10.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.8 | 6.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 4.5 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 4.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.4 | 3.2 | GO:0015250 | water channel activity(GO:0015250) |
| 0.2 | 2.9 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.5 | 2.8 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 2.7 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 3.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 2.8 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 1.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.7 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 1.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.1 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 1.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.9 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.8 | PID TRAIL PATHWAY | TRAIL signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.3 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 6.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 2.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 2.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 2.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 2.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 1.5 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 1.3 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.0 | 1.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |