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PRJNA195909:zebrafish embryo and larva development

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Results for arnt2

Z-value: 2.64

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Transcription factors associated with arnt2

Gene Symbol Gene ID Gene Info
ENSDARG00000103697 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arnt2dr11_v1_chr7_+_10701770_107017700.442.3e-01Click!

Activity profile of arnt2 motif

Sorted Z-values of arnt2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_74090168 6.59 ENSDART00000050528
tyrosinase-related protein 1a
chr14_+_46313135 5.63 ENSDART00000172902
crystallin, beta A1, like 1
chr14_+_46313396 4.95 ENSDART00000047525
crystallin, beta A1, like 1
chr9_-_44295071 4.56 ENSDART00000011837
neuronal differentiation 1
chr7_+_49715750 4.33 ENSDART00000019446
achaete-scute family bHLH transcription factor 1b
chr21_+_6751405 4.19 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr21_+_6751760 4.15 ENSDART00000135914
olfactomedin 1b
chr23_-_6641223 3.20 ENSDART00000023793
major intrinsic protein of lens fiber b
chr18_-_23875219 2.70 ENSDART00000059976
nuclear receptor subfamily 2, group F, member 2
chr17_-_25326296 2.66 ENSDART00000168822
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr5_-_23429228 2.64 ENSDART00000049291
glutamate receptor, ionotropic, AMPA 3a
chr7_-_38340674 2.61 ENSDART00000075782
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr20_+_35382482 2.60 ENSDART00000135284
visinin-like 1a
chr5_+_36932718 2.50 ENSDART00000037879
cone-rod homeobox
chr17_+_52822831 2.47 ENSDART00000193368
Meis homeobox 2a
chr9_+_32978302 2.38 ENSDART00000007630
nescient helix loop helix 2
chr4_+_17417111 2.36 ENSDART00000056005
achaete-scute family bHLH transcription factor 1a
chr1_-_22757145 2.32 ENSDART00000134719
prominin 1 b
chr16_+_23978978 2.22 ENSDART00000058964
ENSDART00000135084
apolipoprotein A-II
chr8_+_29593986 2.17 ENSDART00000077642
atonal bHLH transcription factor 1a
chr18_-_23875370 2.15 ENSDART00000130163
nuclear receptor subfamily 2, group F, member 2
chr21_+_6780340 2.08 ENSDART00000139493
ENSDART00000140478
olfactomedin 1b
chr5_+_34997763 2.06 ENSDART00000043341
forkhead box D1
chr6_-_26559921 2.05 ENSDART00000104532
SRY (sex determining region Y)-box 14
chr11_+_7324704 2.05 ENSDART00000031937
DIRAS family, GTP-binding RAS-like 1a
chr2_+_42724404 2.05 ENSDART00000075392
brain abundant, membrane attached signal protein 1
chr21_-_20711739 1.94 ENSDART00000190918

chr21_+_28958471 1.91 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr24_-_3419998 1.89 ENSDART00000066839
solute carrier family 35, member G2b
chr18_+_7345417 1.88 ENSDART00000041429
GLI pathogenesis-related 1b
chr20_-_20533865 1.83 ENSDART00000125039
SIX homeobox 6b
chr1_-_45633955 1.81 ENSDART00000044057
septin 3
chr1_+_31942961 1.78 ENSDART00000007522
anosmin 1a
chr5_-_48285756 1.77 ENSDART00000183495
myocyte enhancer factor 2cb
chr17_+_22956816 1.76 ENSDART00000079460
latent transforming growth factor beta binding protein 1
chr2_+_29710857 1.74 ENSDART00000021987
pancreas specific transcription factor, 1a
chr11_+_30513656 1.72 ENSDART00000008594
transmembrane protein 178
chr5_+_36415978 1.66 ENSDART00000084464
family with sequence similarity 155, member B
chr17_-_21784152 1.60 ENSDART00000127254
H6 family homeobox 2
chr16_+_19732543 1.60 ENSDART00000149901
ENSDART00000052927
twist family bHLH transcription factor 1b
chr3_+_23737795 1.58 ENSDART00000182247
homeobox B3a
chr15_+_33070939 1.57 ENSDART00000164928
mab-21-like 1
chr18_-_23874929 1.55 ENSDART00000134910
nuclear receptor subfamily 2, group F, member 2
chr8_-_11640240 1.53 ENSDART00000091752
formin binding protein 1a
chr18_+_2837563 1.51 ENSDART00000171495
ENSDART00000160228
family with sequence similarity 168, member A
chr14_+_790166 1.47 ENSDART00000123912
adrenergic, alpha-2D-, receptor a
chr17_+_52823015 1.47 ENSDART00000160507
ENSDART00000186979
Meis homeobox 2a
chr12_+_27117609 1.46 ENSDART00000076154
homeobox B8b
chr23_-_31512496 1.45 ENSDART00000158755
ENSDART00000143425
EYA transcriptional coactivator and phosphatase 4
chr21_-_41305748 1.45 ENSDART00000170457
neuronal vesicle trafficking associated 2
chr1_+_36436936 1.45 ENSDART00000124112
POU class 4 homeobox 2
chr25_+_13406069 1.42 ENSDART00000010495
zinc and ring finger 1
chr14_+_33722950 1.39 ENSDART00000075312
apelin
chr5_-_14344647 1.37 ENSDART00000188456
tet methylcytosine dioxygenase 3
chr8_-_19904124 1.37 ENSDART00000129193
TraB domain containing 2B
chr23_-_26077038 1.36 ENSDART00000126299
GDP dissociation inhibitor 1
chr20_-_47731768 1.36 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr8_+_19674369 1.35 ENSDART00000138176
forkhead box D2
chr10_-_17484762 1.35 ENSDART00000137905
ENSDART00000007961
5'-nucleotidase, cytosolic II, like 1
chr21_+_23953181 1.34 ENSDART00000145541
ENSDART00000065599
ENSDART00000112869
cell adhesion molecule 1a
chr2_+_47581997 1.32 ENSDART00000112579
secretogranin II (chromogranin C), b
chr1_-_22756898 1.32 ENSDART00000158915
prominin 1 b
chr12_-_22540943 1.31 ENSDART00000172310
zinc finger and BTB domain containing 4
chr15_+_38859648 1.31 ENSDART00000141086
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr21_+_19445942 1.30 ENSDART00000030887
solute carrier family 45, member 2
chr15_+_36156986 1.30 ENSDART00000059791
somatostatin 1, tandem duplicate 1
chr17_-_42218652 1.30 ENSDART00000081396
ENSDART00000190007
NK2 homeobox 2a
chr19_-_47452874 1.28 ENSDART00000025931
transcription factor AP-2 epsilon
chr21_+_17768174 1.27 ENSDART00000141380
retinoid X receptor, alpha a
chr14_+_36220479 1.26 ENSDART00000148319
paired-like homeodomain 2
chr19_+_17259912 1.26 ENSDART00000078951
si:ch211-30b16.2
chr10_-_26744131 1.24 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr23_+_22656477 1.24 ENSDART00000009337
ENSDART00000133322
enolase 1a, (alpha)
chr11_-_24428237 1.23 ENSDART00000189107
ENSDART00000103752
dishevelled segment polarity protein 1b
chr14_+_8275115 1.22 ENSDART00000129055
neuregulin 2b
chr4_-_4706893 1.21 ENSDART00000093005

chr5_+_32162684 1.18 ENSDART00000134472
TAO kinase 3b
chr18_-_46208581 1.18 ENSDART00000141278
si:ch211-14c7.2
chr17_+_21919131 1.17 ENSDART00000048136
HtrA serine peptidase 1a
chr6_+_2093206 1.16 ENSDART00000114314
transglutaminase 2b
chr19_+_30387999 1.16 ENSDART00000145396
tetraspanin 13b
chr21_+_5169154 1.16 ENSDART00000102559
zgc:122979
chr9_+_25777270 1.15 ENSDART00000188547
zinc finger E-box binding homeobox 2a
chr19_+_30388186 1.15 ENSDART00000103474
tetraspanin 13b
chr23_-_8373676 1.15 ENSDART00000105135
ENSDART00000158531
opiate receptor-like 1
chr17_+_22956427 1.14 ENSDART00000155145
latent transforming growth factor beta binding protein 1
chr19_+_48176745 1.14 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr9_+_13120419 1.14 ENSDART00000141005
family with sequence similarity 117, member Bb
chr6_+_2093367 1.12 ENSDART00000148396
transglutaminase 2b
chr13_-_40411908 1.12 ENSDART00000057094
ENSDART00000150091
NK2 homeobox 3
chr9_-_23217196 1.12 ENSDART00000083567
kinesin family member 5C
chr4_-_27350820 1.12 ENSDART00000145806
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr19_-_10243148 1.12 ENSDART00000148073
shisa family member 7
chr18_-_44129151 1.11 ENSDART00000087339
cell adhesion associated, oncogene regulated
chr21_+_17110598 1.09 ENSDART00000101282
ENSDART00000191864
breakpoint cluster region
chr23_-_31555696 1.08 ENSDART00000053539
transcription factor 21
chr20_+_34326874 1.08 ENSDART00000061659
influenza virus NS1A binding protein a
chr5_+_23118470 1.07 ENSDART00000149893
neurite extension and migration factor a
chr12_+_35119762 1.06 ENSDART00000085774
si:ch73-127m5.1
chr11_+_36989696 1.05 ENSDART00000045888
transketolase a
chr23_+_10146542 1.04 ENSDART00000048073
zgc:171775
chr16_+_10918252 1.04 ENSDART00000172949
POU class 2 homeobox 2a
chr14_-_17563773 1.04 ENSDART00000082667
fibroblast growth factor receptor like 1a
chr24_-_8831866 1.04 ENSDART00000066780
ENSDART00000143501
glial cells missing homolog 2 (Drosophila)
chr17_+_38262408 1.04 ENSDART00000017493
NK2 homeobox 1
chr24_+_23742690 1.04 ENSDART00000130162
transcription factor 24
chr12_-_431249 1.04 ENSDART00000083827
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr19_+_49721 1.03 ENSDART00000160489
collagen, type XIV, alpha 1b
chr5_-_51619742 1.03 ENSDART00000188537
orthopedia homeobox b
chr10_+_22012389 1.03 ENSDART00000035188
Kv channel interacting protein 1 b
chr19_+_26718074 1.03 ENSDART00000134455
zgc:100906
chr20_+_20637866 1.02 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr7_-_26924903 1.01 ENSDART00000124363
ALX homeobox 4a
chr13_-_30027730 1.00 ENSDART00000044009
stearoyl-CoA desaturase b
chr6_-_55997350 1.00 ENSDART00000011652
EYA transcriptional coactivator and phosphatase 2
chr18_-_44610992 0.99 ENSDART00000125968
ENSDART00000185836
sprouty-related, EVH1 domain containing 3
chr19_+_15571290 0.99 ENSDART00000131134
forkhead box O6 b
chr23_-_44494401 0.99 ENSDART00000114640
ENSDART00000148532
actin-like 6B
chr13_+_27314795 0.98 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr15_-_18574716 0.96 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr16_+_46294337 0.96 ENSDART00000040769
nuclear receptor subfamily 2, group F, member 5
chr4_-_2867461 0.95 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr14_-_7885707 0.94 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr9_-_6661657 0.94 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
POU class 3 homeobox 3a
chr17_+_21964472 0.94 ENSDART00000063704
ENSDART00000188904
cysteine-rich protein 3
chr18_+_49411417 0.94 ENSDART00000028944
zmp:0000001073
chr9_-_1978090 0.93 ENSDART00000082344
homeobox D11a
chr6_+_42818963 0.92 ENSDART00000184833
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr15_-_12319065 0.92 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr4_-_22311610 0.92 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr14_+_16813816 0.91 ENSDART00000161201
LIM and calponin homology domains 1b
chr6_+_4872883 0.90 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
protocadherin 9
chr24_+_23791758 0.89 ENSDART00000066655
ENSDART00000146580
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr4_-_12007404 0.89 ENSDART00000092250
BTB (POZ) domain containing 11a
chr7_+_20017211 0.89 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr18_+_5490668 0.88 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr13_+_12299997 0.88 ENSDART00000108535
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr4_+_7888047 0.88 ENSDART00000104676
calcium/calmodulin-dependent protein kinase 1Da
chr10_+_36650222 0.87 ENSDART00000126963
uncoupling protein 3
chr16_-_33059246 0.87 ENSDART00000171718
ENSDART00000168305
ENSDART00000166401
synaptosomal-associated protein 91
chr3_+_23726148 0.87 ENSDART00000174580
homeobox B3a
chr5_+_48683447 0.87 ENSDART00000008043
adhesion G protein-coupled receptor V1
chr20_-_8419057 0.86 ENSDART00000145841
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr18_-_3166726 0.86 ENSDART00000165002
aquaporin 11
chr17_-_22067451 0.85 ENSDART00000156872
tau tubulin kinase 1b
chr10_-_15919839 0.85 ENSDART00000065032
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr20_+_826459 0.85 ENSDART00000104740
5'-nucleotidase, ecto (CD73)
chr5_+_30179010 0.85 ENSDART00000134624
ADAM metallopeptidase with thrombospondin type 1 motif, 15a
chr1_+_33383971 0.85 ENSDART00000150043
dehydrogenase/reductase (SDR family) X-linked
chr5_-_16983336 0.84 ENSDART00000038740
polypeptide N-acetylgalactosaminyltransferase 9
chr4_-_17055782 0.84 ENSDART00000134595
SRY (sex determining region Y)-box 5
chr6_-_32703317 0.84 ENSDART00000064833
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr9_-_34945566 0.84 ENSDART00000131908
ENSDART00000059861
DCN1, defective in cullin neddylation 1, domain containing 2a
chr19_-_10395683 0.84 ENSDART00000109488
zgc:194578
chr13_+_12739283 0.83 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr7_+_55633483 0.83 ENSDART00000180993
ENSDART00000184845
trafficking protein particle complex 2-like
chr6_-_18698006 0.82 ENSDART00000170128
rhomboid, veinlet-like 3 (Drosophila)
chr24_+_26932472 0.82 ENSDART00000192288
ENSDART00000079848
TNF superfamily member 10
chr14_-_26704829 0.82 ENSDART00000078563
neurogenin 1
chr23_+_31107685 0.82 ENSDART00000103448
T-box 18
chr3_-_26109322 0.82 ENSDART00000113780
zgc:162612
chr3_+_14768364 0.81 ENSDART00000090235
ENSDART00000139001
nuclear factor I/Xb
chr13_+_31603988 0.81 ENSDART00000030646
SIX homeobox 6a
chr17_-_21441464 0.80 ENSDART00000031490
ventral anterior homeobox 1
chr1_+_37195465 0.80 ENSDART00000043855
ENSDART00000192580
ENSDART00000181666
doublecortin-like kinase 2a
chr20_-_6812688 0.80 ENSDART00000170934
insulin-like growth factor binding protein 1a
chr3_+_18097700 0.79 ENSDART00000021634
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr5_-_22952156 0.78 ENSDART00000111146
si:ch211-26b3.4
chr5_-_38121612 0.78 ENSDART00000159543
si:ch211-284e13.6
chr3_-_25813426 0.78 ENSDART00000039482
netrin 1b
chr17_+_27434626 0.78 ENSDART00000052446
vestigial-like family member 2b
chr19_-_5369486 0.78 ENSDART00000105004
keratin 17
chr19_+_41464870 0.78 ENSDART00000102778
distal-less homeobox 6a
chr7_+_25858380 0.77 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr20_-_29505863 0.76 ENSDART00000148278
Kruppel-like factor 11a
chr13_-_31296358 0.76 ENSDART00000030946
PR domain containing 8
chr15_+_28482862 0.75 ENSDART00000015286
ENSDART00000154320
ankyrin repeat domain 13B
chr17_+_17861681 0.75 ENSDART00000123311
isthmin 2a
chr4_-_25181552 0.75 ENSDART00000066930
ATP synthase F1 subunit gamma
chr23_+_17220986 0.74 ENSDART00000054761
nucleolar protein 4-like b
chr21_-_25522510 0.74 ENSDART00000162711
connector enhancer of kinase suppressor of Ras 2b
chr1_+_33969015 0.73 ENSDART00000042984
ENSDART00000146530
eph receptor A6
chr1_-_22512063 0.72 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr2_+_6991208 0.72 ENSDART00000182239
discoidin domain receptor tyrosine kinase 2b
chr3_-_3496738 0.71 ENSDART00000186849

chr6_-_11614339 0.71 ENSDART00000080589
GULP, engulfment adaptor PTB domain containing 1b
chr6_-_7720332 0.71 ENSDART00000135945
ribosomal protein SA
chr1_-_49434798 0.71 ENSDART00000150842
ENSDART00000150789
si:dkeyp-80c12.10
chr13_+_24022963 0.70 ENSDART00000028285
piggyBac transposable element derived 5
chr1_+_25783801 0.70 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_10888762 0.70 ENSDART00000136049
synaptotagmin X
chr13_+_22119798 0.70 ENSDART00000173206
ENSDART00000078652
ENSDART00000165842
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2
chr3_-_62380146 0.69 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr6_+_33537267 0.69 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr2_-_10188598 0.69 ENSDART00000189122
diencephalon/mesencephalon homeobox 1a
chr15_+_7054754 0.68 ENSDART00000149800
forkhead box L2a
chr21_+_30194904 0.68 ENSDART00000137023
ENSDART00000078403
si:ch211-59d17.3
chr1_+_37195919 0.68 ENSDART00000159684
ENSDART00000172742
ENSDART00000158395
doublecortin-like kinase 2a
chr1_+_42225060 0.67 ENSDART00000138740
ENSDART00000101306
catenin (cadherin-associated protein), alpha 2
chr14_+_32022272 0.67 ENSDART00000105760
zic family member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of arnt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.8 2.5 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.7 6.6 GO:0042438 melanin biosynthetic process(GO:0042438)
0.7 2.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 2.4 GO:0061549 sympathetic ganglion development(GO:0061549)
0.6 1.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.5 3.2 GO:0006833 water transport(GO:0006833)
0.4 1.3 GO:0060031 mediolateral intercalation(GO:0060031)
0.4 1.3 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 2.1 GO:0006972 hyperosmotic response(GO:0006972)
0.4 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.4 2.1 GO:0061551 trigeminal ganglion development(GO:0061551)
0.4 1.1 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.3 5.5 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.3 1.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.3 0.9 GO:0097264 self proteolysis(GO:0097264)
0.3 1.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 1.4 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 1.1 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 0.5 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.3 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 0.8 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.3 1.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.3 1.3 GO:0061072 iris morphogenesis(GO:0061072)
0.3 1.0 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.9 GO:0006867 asparagine transport(GO:0006867)
0.2 1.4 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 0.7 GO:0071312 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.2 0.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 1.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 0.4 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.2 0.6 GO:0007414 axonal defasciculation(GO:0007414)
0.2 1.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 1.0 GO:0051701 interaction with host(GO:0051701)
0.2 3.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 0.8 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.2 0.6 GO:2000425 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
0.2 1.2 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.0 GO:0021767 mammillary body development(GO:0021767)
0.2 1.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 1.0 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 1.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.4 GO:0045191 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.6 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 1.0 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.8 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 3.3 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 0.4 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 3.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.5 GO:0048557 embryonic digestive tract morphogenesis(GO:0048557) post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.5 GO:0061010 gall bladder development(GO:0061010)
0.1 0.3 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 0.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 2.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.0 GO:0021592 fourth ventricle development(GO:0021592)
0.1 1.1 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 4.8 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.1 0.4 GO:0097037 heme export(GO:0097037)
0.1 0.5 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.8 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 2.9 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.3 GO:2000257 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.1 0.7 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.4 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.1 GO:0019233 sensory perception of pain(GO:0019233)
0.1 0.7 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 10.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.6 GO:0035777 pronephric distal tubule development(GO:0035777)
0.1 1.2 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.7 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.3 GO:0060307 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.6 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 2.2 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.2 GO:0015677 copper ion import(GO:0015677)
0.1 0.7 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
0.1 0.8 GO:0045116 protein neddylation(GO:0045116)
0.1 1.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) visceral serous pericardium development(GO:0061032) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 2.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0072178 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.0 0.2 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.9 GO:0070142 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 0.8 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.7 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.9 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.6 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.9 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.0 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.4 GO:0060914 heart formation(GO:0060914)
0.0 2.6 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 2.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.6 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.0 0.4 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.7 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 1.2 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.4 GO:0099590 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943) neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.8 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.5 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 2.8 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.8 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.1 GO:0050764 regulation of phagocytosis(GO:0050764)
0.0 0.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.0 GO:0021610 facial nerve morphogenesis(GO:0021610) facial nerve formation(GO:0021611)
0.0 0.7 GO:0016331 morphogenesis of embryonic epithelium(GO:0016331)
0.0 0.4 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0036353 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.2 GO:0035138 pectoral fin morphogenesis(GO:0035138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.6 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 2.8 GO:0005955 calcineurin complex(GO:0005955)
0.5 3.6 GO:0071914 prominosome(GO:0071914)
0.3 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 0.9 GO:0016460 myosin II complex(GO:0016460)
0.2 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.2 0.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 0.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 0.5 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.9 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.7 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.2 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 4.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0016586 RSC complex(GO:0016586)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.9 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.1 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.0 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.8 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 27.7 GO:0005576 extracellular region(GO:0005576)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 3.0 GO:0030424 axon(GO:0030424)
0.0 2.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.4 GO:0001972 retinoic acid binding(GO:0001972)
0.5 2.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 1.4 GO:0031704 apelin receptor binding(GO:0031704)
0.5 1.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.4 3.2 GO:0015250 water channel activity(GO:0015250)
0.3 1.9 GO:0070888 E-box binding(GO:0070888)
0.3 1.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 1.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.7 GO:0016496 substance P receptor activity(GO:0016496)
0.2 0.9 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.2 0.7 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.2 0.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 2.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 2.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 1.3 GO:0015154 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.9 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.2 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 10.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.9 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.4 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 2.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 1.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 18.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.4 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 31.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0030552 sodium channel activity(GO:0005272) cAMP binding(GO:0030552)
0.0 1.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.8 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.0 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 7.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 3.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 2.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 2.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 6.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion