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PRJNA195909:zebrafish embryo and larva development

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Results for arid3a+arid3b+arid3c

Z-value: 0.92

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Transcription factors associated with arid3a+arid3b+arid3c

Gene Symbol Gene ID Gene Info
ENSDARG00000067729 AT rich interactive domain 3C (BRIGHT-like)
ENSDARG00000070843 AT rich interactive domain 3A (BRIGHT-like)
ENSDARG00000104034 AT rich interactive domain 3B (BRIGHT-like)
ENSDARG00000114447 AT rich interactive domain 3C (BRIGHT-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid3cdr11_v1_chr5_+_41322783_413227830.274.8e-01Click!
arid3adr11_v1_chr11_+_5681762_56817620.196.3e-01Click!
arid3bdr11_v1_chr25_-_29072162_290721620.078.7e-01Click!

Activity profile of arid3a+arid3b+arid3c motif

Sorted Z-values of arid3a+arid3b+arid3c motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_24343363 1.48 ENSDART00000166392
family with sequence similarity 131, member C
chr19_+_4139065 1.25 ENSDART00000172524
si:dkey-218f9.10
chr21_-_42831033 1.09 ENSDART00000160998
serine/threonine kinase 10
chr17_-_4245902 1.05 ENSDART00000151851
growth differentiation factor 3
chr2_-_39558643 0.79 ENSDART00000139860
ENSDART00000145231
ENSDART00000141721
cerebellin 7
chr15_+_39096736 0.77 ENSDART00000129511
ENSDART00000014877
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr24_-_15208414 0.75 ENSDART00000145978
rotatin
chr12_+_1609563 0.67 ENSDART00000163559
solute carrier family 39 member 11
chr8_-_29930821 0.59 ENSDART00000125173
excision repair cross-complementation group 6-like 2
chr20_+_35208020 0.59 ENSDART00000153315
ENSDART00000045135
F-box protein 16
chr10_+_16911951 0.57 ENSDART00000164933
unc-13 homolog B
chr20_-_27190393 0.56 ENSDART00000149024
BTB (POZ) domain containing 7
chr11_+_41459408 0.55 ENSDART00000182285
parkinson protein 7
chr15_+_38308421 0.55 ENSDART00000129941
si:dkey-24p1.6
chr12_+_3871452 0.54 ENSDART00000066546
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr12_-_13650344 0.54 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
signal transducer and activator of transcription 5b
chr24_+_37484661 0.53 ENSDART00000165125
ENSDART00000109221
WD repeat domain 90
chr15_+_47362728 0.50 ENSDART00000180712

chr10_+_45031398 0.47 ENSDART00000160536
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr8_+_3820134 0.44 ENSDART00000122454
citron rho-interacting serine/threonine kinase b
chr19_-_7406933 0.44 ENSDART00000151137
oxidation resistance 1b
chr14_-_7045009 0.44 ENSDART00000112082
RUN and FYVE domain containing 1
chr14_+_30340251 0.44 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr17_+_22311413 0.43 ENSDART00000151929
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr3_+_7808459 0.43 ENSDART00000162374
hook microtubule-tethering protein 2
chr15_+_45994123 0.43 ENSDART00000124704
leucine rich repeat and fibronectin type III domain containing 1
chr15_-_31109760 0.42 ENSDART00000154254
kinase suppressor of ras 1b
chr5_+_44895949 0.42 ENSDART00000193822
KN motif and ankyrin repeat domains 1a
chr18_+_11858397 0.42 ENSDART00000133762
transmembrane and tetratricopeptide repeat containing 2b
chr9_+_33220342 0.42 ENSDART00000100893
ENSDART00000113451
si:ch211-125e6.13
chr5_+_22579975 0.42 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr7_+_9189547 0.40 ENSDART00000169783
proprotein convertase subtilisin/kexin type 6
chr1_-_53468160 0.39 ENSDART00000143349
zgc:66455
chr16_+_1100559 0.38 ENSDART00000092657
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr12_+_2995887 0.38 ENSDART00000189499
ENSDART00000182597
ENSDART00000184918
ENSDART00000182292
leucine rich repeat containing 45
chr7_+_36467315 0.37 ENSDART00000138893
akt interacting protein
chr2_+_25657958 0.37 ENSDART00000161407
TRAF2 and NCK interacting kinase a
chr14_+_45028062 0.37 ENSDART00000184717
ENSDART00000185481
ATPase phospholipid transporting 8A1
chr21_-_21465111 0.37 ENSDART00000141487
nectin cell adhesion molecule 3b
chr14_+_28281744 0.36 ENSDART00000173292
midline 2
chr14_+_35428152 0.36 ENSDART00000172597
synaptotagmin-like 4
chr9_-_27398369 0.36 ENSDART00000186499
testis expressed 30
chr22_+_25753972 0.35 ENSDART00000188417

chr19_+_32401278 0.35 ENSDART00000184353
ataxin 1a
chr17_-_7060477 0.35 ENSDART00000081797
SAM and SH3 domain containing 1b
chr20_+_35247410 0.34 ENSDART00000153098
ENSDART00000182470
F-box protein 16
chr11_-_26832685 0.34 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr10_+_20392083 0.34 ENSDART00000166867
R3H domain and coiled-coil containing 1
chr9_+_29548195 0.34 ENSDART00000176057
ring finger protein 17
chr22_+_12366516 0.34 ENSDART00000157802
R3H domain containing 1
chr10_+_44584614 0.34 ENSDART00000163523
seizure related 6 homolog (mouse)-like
chr12_-_48188928 0.33 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr2_+_49232559 0.33 ENSDART00000154285
ENSDART00000175147
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr21_-_3606539 0.33 ENSDART00000062418
dymeclin
chr8_+_9715010 0.32 ENSDART00000139414
GRIP1 associated protein 1
chr3_+_46271911 0.32 ENSDART00000186557
ENSDART00000113531
MKL/myocardin-like 2b
chr11_-_891674 0.32 ENSDART00000172904
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr15_+_34592215 0.32 ENSDART00000099776
tetraspanin 13a
chr4_-_75157223 0.31 ENSDART00000174127

chr3_-_55537096 0.31 ENSDART00000123544
ENSDART00000188752
testis expressed 2
chr24_-_20152965 0.31 ENSDART00000147004
oxidative stress responsive 1b
chr7_-_51749683 0.31 ENSDART00000083190
histone deacetylase 8
chr6_-_16394528 0.30 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr6_-_7052408 0.30 ENSDART00000150033
ENSDART00000149232
bridging integrator 1b
chr19_-_11208782 0.30 ENSDART00000044426
ENSDART00000189754
si:dkey-240h12.4
chr15_+_20530649 0.30 ENSDART00000186312
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr2_+_34967022 0.30 ENSDART00000134926
astrotactin 1
chr21_+_10712823 0.29 ENSDART00000123476
lectin, mannose-binding, 1
chr3_-_5228841 0.29 ENSDART00000092373
ENSDART00000182438
myosin, heavy chain 9b, non-muscle
chr6_-_9563534 0.28 ENSDART00000184765
mitogen-activated protein kinase kinase kinase 2
chr12_-_33659328 0.28 ENSDART00000153457
transmembrane protein 94
chr23_-_32100106 0.28 ENSDART00000044658
LETM1 domain containing 1
chr16_+_32014552 0.28 ENSDART00000047570
membrane bound O-acyltransferase domain containing 7
chr2_-_57916317 0.27 ENSDART00000183930
si:dkeyp-68b7.7
chr6_+_47843760 0.27 ENSDART00000140943
peptidyl arginine deiminase, type II
chr18_-_48296793 0.27 ENSDART00000032184
ENSDART00000193076

chr23_+_2666944 0.27 ENSDART00000192861

chr13_+_35689749 0.26 ENSDART00000158726
proteasome activator subunit 4a
chr21_+_36623162 0.26 ENSDART00000027459
G protein-coupled receptor kinase 6
chr5_+_66433287 0.26 ENSDART00000170757
kinetochore associated 1
chr12_+_47698356 0.26 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr21_+_3093419 0.26 ENSDART00000162520
SHC adaptor protein 3
chr12_-_18961289 0.26 ENSDART00000168405
E1A binding protein p300 a
chr14_+_30413758 0.26 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr17_+_24222190 0.25 ENSDART00000181698
ENSDART00000189411
EH domain binding protein 1
chr13_+_6092135 0.25 ENSDART00000162738
family with sequence similarity 120B
chr25_-_6420800 0.25 ENSDART00000153768
protein tyrosine phosphatase, non-receptor type 9, a
chr16_-_4610255 0.25 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
aryl hydrocarbon receptor nuclear translocator
chr15_-_34408777 0.25 ENSDART00000139934
alkylglycerol monooxygenase
chr4_+_25912308 0.25 ENSDART00000167845
ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr10_-_14943281 0.25 ENSDART00000143608
SMAD family member 2
chr16_+_26747766 0.24 ENSDART00000183257
RAD54 homolog B (S. cerevisiae)
chr5_-_42180205 0.24 ENSDART00000145247
family with sequence similarity 222, member Ba
chr22_+_1170294 0.24 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr21_-_20322816 0.24 ENSDART00000135472
zgc:86764
chr11_-_2504750 0.24 ENSDART00000173149
diacylglycerol kinase, alpha b
chr5_+_66250856 0.24 ENSDART00000132789
SECIS binding protein 2
chr20_+_18943406 0.24 ENSDART00000193590
myotubularin related protein 9
chr8_+_25145464 0.23 ENSDART00000136505
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr15_+_26941063 0.23 ENSDART00000149957
breast carcinoma amplified sequence 3
chr5_+_6672870 0.23 ENSDART00000126598
paxillin a
chr4_-_5775507 0.23 ENSDART00000021753
cyclin C
chr8_+_25892319 0.23 ENSDART00000187167
ENSDART00000078163
transmembrane protein 115
chr5_-_67349916 0.23 ENSDART00000144092
MLX interacting protein
chr5_+_69650148 0.23 ENSDART00000097244
general transcription factor IIH, polypeptide 3
chr20_+_46741074 0.23 ENSDART00000145294
si:ch211-57i17.1
chr17_-_29213710 0.22 ENSDART00000076481
EH-domain containing 4
chr8_-_29822527 0.22 ENSDART00000167487
solute carrier family 20 (phosphate transporter), member 2
chr21_+_6397463 0.22 ENSDART00000136539
si:ch211-225g23.1
chr23_-_37291793 0.22 ENSDART00000083281
ENSDART00000187108
mitochondrial E3 ubiquitin protein ligase 1b
chr12_+_2428247 0.22 ENSDART00000152529
leucine rich repeat containing 18b
chr11_-_889845 0.22 ENSDART00000162152
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr10_-_2522588 0.22 ENSDART00000081926

chr12_-_34258384 0.22 ENSDART00000109196
phosphatidylglycerophosphate synthase 1
chr17_+_45472608 0.22 ENSDART00000103493
ENSDART00000183474
zgc:110783
chr15_-_38129845 0.21 ENSDART00000057095
si:dkey-24p1.1
chr23_-_18707418 0.21 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr25_+_34407529 0.21 ENSDART00000156751
si:dkey-37f18.2
chr11_-_21404358 0.21 ENSDART00000129062
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr8_+_48965767 0.21 ENSDART00000008058
AP2 associated kinase 1a
chr16_+_36126310 0.21 ENSDART00000166040
ENSDART00000189802
SH3-domain binding protein 5b (BTK-associated)
chr4_-_75158035 0.21 ENSDART00000174353

chr8_+_10001805 0.20 ENSDART00000132894
si:dkey-8e10.2
chr17_-_1174960 0.20 ENSDART00000161202
DnaJ (Hsp40) homolog, subfamily C, member 17
chr14_+_3507326 0.20 ENSDART00000159326
glutathione S-transferase pi 1
chr7_+_48297842 0.20 ENSDART00000052123
solute carrier family 25, member 44 b
chr6_+_49551614 0.20 ENSDART00000022581
RAB22A, member RAS oncogene family
chr12_+_38774860 0.20 ENSDART00000130371
kinesin family member 19
chr7_-_51749895 0.20 ENSDART00000175523
ENSDART00000189639
histone deacetylase 8
chr13_+_24671481 0.19 ENSDART00000001678
ADAM metallopeptidase domain 8a
chr23_+_4777348 0.19 ENSDART00000171971
vestigial-like family member 4a
chr13_-_50341004 0.19 ENSDART00000038120
CDK2 associated cullin domain 1
chr22_+_30047245 0.19 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
adducin 3 (gamma) a
chr25_-_13549577 0.19 ENSDART00000166772
anoctamin 10b
chr6_-_33871055 0.19 ENSDART00000115409
microtubule associated serine/threonine kinase 2
chr22_-_3275888 0.19 ENSDART00000164743
si:zfos-943e10.1
chr10_-_16868211 0.18 ENSDART00000171755
stomatin (EPB72)-like 2
chr18_+_6641542 0.18 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr25_+_34407740 0.18 ENSDART00000012677
si:dkey-37f18.2
chr24_+_7323894 0.18 ENSDART00000192873
X-ray repair cross complementing 2
chr13_+_25199849 0.18 ENSDART00000139209
ENSDART00000130876
adaptor-related protein complex 3, mu 1 subunit
chr3_-_13509283 0.18 ENSDART00000166832
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr9_+_18829360 0.18 ENSDART00000006514
general transcription factor IIF, polypeptide 2b
chr9_+_21306902 0.18 ENSDART00000138554
ENSDART00000004108
exportin 4
chr1_+_35956435 0.17 ENSDART00000085021
ENSDART00000148505
methylmalonic aciduria (cobalamin deficiency) cblA type
chr1_+_23372470 0.17 ENSDART00000187503
ENSDART00000087658
NEDD4 binding protein 2
chr15_+_33843596 0.17 ENSDART00000169037
inositol polyphosphate-5-phosphatase Ka
chr2_+_10878406 0.17 ENSDART00000091497
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr6_-_8360918 0.17 ENSDART00000004716
acid phosphatase 5a, tartrate resistant
chr9_+_33158191 0.17 ENSDART00000180786
dopey family member 2
chr3_-_29671653 0.17 ENSDART00000132083
sulfotransferase family 3, cytosolic sulfotransferase 1
chr15_-_1733235 0.17 ENSDART00000023153
ENSDART00000154668
RAB guanine nucleotide exchange factor (GEF) 1, like
chr21_+_40695345 0.17 ENSDART00000143594
coiled-coil domain containing 82
chr5_-_26284276 0.17 ENSDART00000148608
ARVCF, delta catenin family member b
chr3_+_22036113 0.17 ENSDART00000132190
cell division cycle 27
chr5_-_25576462 0.17 ENSDART00000165147
si:dkey-229d2.4
chr23_-_9965148 0.17 ENSDART00000137308
plexin b1a
chr16_+_22345513 0.17 ENSDART00000078000
zgc:123238
chr15_-_3534705 0.17 ENSDART00000158150
component of oligomeric golgi complex 6
chr12_+_14556092 0.17 ENSDART00000115237
beclin 1, autophagy related
chr11_+_22109887 0.17 ENSDART00000122136
si:dkey-91m3.1
chr1_+_35473219 0.17 ENSDART00000109678
ENSDART00000181635
ubiquitin specific peptidase 38
chr22_-_547748 0.17 ENSDART00000037455
ENSDART00000140101
cyclin D3
chr14_-_36763302 0.17 ENSDART00000074786
cathepsin O
chr1_+_52662203 0.16 ENSDART00000141530
oxysterol binding protein
chr18_-_21910991 0.16 ENSDART00000089787
ENSDART00000169220
ENSDART00000132381
ENSDART00000191764
enhancer of mRNA decapping 4
chr7_+_1530024 0.16 ENSDART00000163082
TOX high mobility group box family member 4 b
chr14_+_46342882 0.16 ENSDART00000193707
ENSDART00000060577
transmembrane protein 33
chr25_-_518656 0.16 ENSDART00000156421
myosin IXAb
chr1_+_51903413 0.16 ENSDART00000135861
nuclear factor I/Xa
chr24_-_36187094 0.16 ENSDART00000111891
establishment of sister chromatid cohesion N-acetyltransferase 1
chr11_-_31276064 0.16 ENSDART00000141062
ENSDART00000004780
mannosidase, alpha, class 2B, member 1
chr12_+_48803098 0.16 ENSDART00000074768
peptidylprolyl isomerase Fb
chr11_+_2687395 0.15 ENSDART00000082510
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr22_-_10891213 0.15 ENSDART00000145229
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr12_-_18414536 0.15 ENSDART00000132956
ENSDART00000078724
ATP synthase mitochondrial F1 complex assembly factor 2
chr19_-_31372896 0.15 ENSDART00000046609
scinderin
chr1_-_52790724 0.15 ENSDART00000139577
ENSDART00000100937
protein associated with topoisomerase II homolog 1 (yeast)
chr22_-_7702958 0.15 ENSDART00000193046
si:ch211-59h6.1
chr19_-_8798178 0.15 ENSDART00000188232
ceramide synthase 2a
chr9_+_33009284 0.15 ENSDART00000036926
VANGL planar cell polarity protein 1
chr19_+_43753995 0.15 ENSDART00000058504
si:ch1073-513e17.1
chr3_+_60828813 0.15 ENSDART00000128260

chr20_+_37825804 0.15 ENSDART00000152865
TatD DNase domain containing 3
chr7_-_51300277 0.15 ENSDART00000174174
guanylyl cyclase 2
chr9_+_38502524 0.15 ENSDART00000087229
leishmanolysin-like (metallopeptidase M8 family)
chr3_+_17634952 0.15 ENSDART00000191833
RAB5C, member RAS oncogene family
chr9_+_2522797 0.15 ENSDART00000186786
ENSDART00000147034
G protein-coupled receptor 155a
chr5_+_64900223 0.14 ENSDART00000191677
prostaglandin-endoperoxide synthase 1
chr22_-_10752471 0.14 ENSDART00000081191
SAS-6 centriolar assembly protein
chr11_-_875381 0.14 ENSDART00000173325
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr13_+_18371208 0.14 ENSDART00000138172
cell division cycle and apoptosis regulator 1
chr22_+_18389271 0.14 ENSDART00000088270
YjeF N-terminal domain containing 3
chr7_-_7692723 0.14 ENSDART00000183352
aminoadipate aminotransferase
chr5_+_50371951 0.14 ENSDART00000184488
ENSDART00000171295
SMC5-SMC6 complex localization factor 1
chr9_+_34380299 0.14 ENSDART00000131705
lysosomal-associated membrane protein 1
chr8_+_32389838 0.14 ENSDART00000076350
ENSDART00000146901
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
chr13_+_25200105 0.14 ENSDART00000039640
adaptor-related protein complex 3, mu 1 subunit
chr13_+_4883377 0.14 ENSDART00000181530
ENSDART00000092521
mitochondrial calcium uptake 1
chr1_+_14020445 0.14 ENSDART00000079716
histone PARylation factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of arid3a+arid3b+arid3c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.2 0.6 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.8 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.3 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0015695 organic cation transport(GO:0015695)
0.1 0.3 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 1.1 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.3 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.0 0.2 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.1 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0045453 bone resorption(GO:0045453)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0070265 regulation of mitochondrial membrane permeability(GO:0046902) necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.2 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 1.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation