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PRJNA195909:zebrafish embryo and larva development

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Results for alx4a+alx4b

Z-value: 0.62

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Transcription factors associated with alx4a+alx4b

Gene Symbol Gene ID Gene Info
ENSDARG00000074442 ALX homeobox 4b
ENSDARG00000088332 ALX homeobox 4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx4bdr11_v1_chr18_+_38321039_383210390.844.5e-03Click!
alx4adr11_v1_chr7_-_26924903_269249030.771.5e-02Click!

Activity profile of alx4a+alx4b motif

Sorted Z-values of alx4a+alx4b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22099536 2.00 ENSDART00000101923

chr17_+_15433671 1.35 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr17_+_15433518 1.35 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr3_-_32818607 1.23 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr25_+_29161609 1.19 ENSDART00000180752
pyruvate kinase M1/2b
chr4_+_9669717 1.19 ENSDART00000004604
si:dkey-153k10.9
chr12_-_35830625 1.17 ENSDART00000180028

chr25_+_31276842 1.15 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr20_+_19512727 1.10 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr3_-_55128258 1.06 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr9_-_22129788 0.98 ENSDART00000124272
ENSDART00000175417
crystallin, gamma M2d8
chr4_+_16885854 0.88 ENSDART00000017726
ethanolamine kinase 1
chr14_-_413273 0.88 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr3_+_28939759 0.87 ENSDART00000141904
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr8_+_31435452 0.85 ENSDART00000145282
selenoprotein P
chr21_+_25236297 0.80 ENSDART00000112783
transmembrane protein 45B
chr13_-_29420885 0.79 ENSDART00000024225
choline O-acetyltransferase a
chr14_-_4145594 0.78 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr5_-_41494831 0.72 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr9_-_14504834 0.72 ENSDART00000056103
neuropilin 2b
chr21_+_28958471 0.71 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_+_10855158 0.70 ENSDART00000172219
ENSDART00000170826
apolipoprotein Ea
chr24_-_40860603 0.70 ENSDART00000188032

chr23_-_23401305 0.69 ENSDART00000078936
hairy-related 9
chr17_-_12336987 0.66 ENSDART00000172001
synaptosomal-associated protein, 25b
chr18_-_48983690 0.65 ENSDART00000182359

chr12_+_13118540 0.64 ENSDART00000077840
ENSDART00000127870
calymmin
chr18_+_2837563 0.64 ENSDART00000171495
ENSDART00000160228
family with sequence similarity 168, member A
chr11_+_30057762 0.64 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr21_+_45841731 0.63 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr6_-_607063 0.62 ENSDART00000189900
lectin, galactoside-binding, soluble, 2b
chr22_+_11775269 0.62 ENSDART00000140272
keratin 96
chr19_+_12915498 0.62 ENSDART00000132892
collagen triple helix repeat containing 1a
chr6_-_7720332 0.61 ENSDART00000135945
ribosomal protein SA
chr19_+_43297546 0.61 ENSDART00000168002
lysosomal protein transmembrane 5
chr2_-_38000276 0.61 ENSDART00000034790
Purkinje cell protein 4 like 1
chr22_+_16535575 0.61 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr16_-_28856112 0.60 ENSDART00000078543
synaptotagmin XIb
chr4_-_9891874 0.59 ENSDART00000067193
adrenomedullin 2a
chr15_-_22074315 0.59 ENSDART00000149830
dopamine receptor D2a
chr15_-_12011390 0.59 ENSDART00000187403
si:dkey-202l22.6
chr14_+_45406299 0.58 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr15_-_5815006 0.58 ENSDART00000102459
retinol binding protein 2a, cellular
chr7_-_73752955 0.58 ENSDART00000171254
ENSDART00000009888
calsequestrin 1b
chr7_-_66877058 0.57 ENSDART00000155954
adrenomedullin a
chr3_-_53533128 0.56 ENSDART00000183591
notch 3
chr17_+_41992054 0.56 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr6_+_35362225 0.56 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr8_+_7359294 0.55 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr24_-_7697274 0.54 ENSDART00000186077
synaptotagmin Vb
chr23_-_42232124 0.54 ENSDART00000149944
glutathione peroxidase 7
chr21_-_19314618 0.54 ENSDART00000188744
glycerol-3-phosphate acyltransferase 3
chr11_-_7261717 0.53 ENSDART00000128959
zgc:113223
chr15_+_23799461 0.53 ENSDART00000154885
si:ch211-167j9.4
chr8_+_34731982 0.53 ENSDART00000066050
4-hydroxyphenylpyruvate dioxygenase b
chr3_+_28953274 0.52 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr10_-_14556978 0.52 ENSDART00000126643
zgc:153395
chr14_-_49063157 0.51 ENSDART00000021260
septin 8b
chr24_+_21621654 0.51 ENSDART00000002595
ribosomal protein L21
chr2_+_35728033 0.51 ENSDART00000002094
ankyrin repeat domain 45
chr8_+_23738122 0.50 ENSDART00000062983
ribosomal protein L10a
chr23_+_44741500 0.49 ENSDART00000166421
ATPase Na+/K+ transporting subunit beta 2a
chr10_-_43771447 0.49 ENSDART00000052307
arrestin domain containing 3b
chr3_-_12930217 0.48 ENSDART00000166322
platelet-derived growth factor alpha polypeptide b
chr13_-_22862133 0.48 ENSDART00000138563
phenazine biosynthesis-like protein domain containing 2
chr6_+_47424266 0.48 ENSDART00000171087
si:ch211-286o17.1
chr23_-_21446985 0.47 ENSDART00000044080
hairy-related 12
chr15_-_3736773 0.47 ENSDART00000090624
lysophosphatidic acid receptor 6a
chr18_+_21408794 0.47 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr16_+_6864608 0.47 ENSDART00000078306
rho/rac guanine nucleotide exchange factor (GEF) 2
chr25_-_13569234 0.47 ENSDART00000189645
fatty acid 2-hydroxylase
chr24_-_37955993 0.46 ENSDART00000041805
meteorin, glial cell differentiation regulator
chr1_-_669717 0.46 ENSDART00000160564
cysteine/tyrosine-rich 1
chr2_-_30668580 0.46 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr18_-_48547564 0.45 ENSDART00000138607
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr15_-_47848544 0.44 ENSDART00000098711
eukaryotic translation initiation factor 3, subunit K
chr10_-_26744131 0.44 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr24_-_25691020 0.44 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr1_+_127250 0.43 ENSDART00000003463
coagulation factor VIIi
chr20_-_23439011 0.43 ENSDART00000022887
solute carrier family 10, member 4
chr11_-_45141309 0.43 ENSDART00000181736
calcium activated nucleotidase 1b
chr1_-_46981134 0.43 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr1_+_59293873 0.42 ENSDART00000168036
retinol dehydrogenase 8b
chr5_+_71802014 0.42 ENSDART00000124939
ENSDART00000097164
LIM homeobox 3
chr20_-_9436521 0.42 ENSDART00000133000
zgc:101840
chr22_-_23748284 0.41 ENSDART00000162005
complement factor H like 2
chr16_-_12173554 0.41 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr5_+_64739762 0.41 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfactomedin 1a
chr3_-_57666518 0.41 ENSDART00000102062
TIMP metallopeptidase inhibitor 2b
chr6_-_58764672 0.40 ENSDART00000154322
sterol O-acyltransferase 2
chr25_+_5039050 0.40 ENSDART00000154700
parvin, beta
chr8_+_6863462 0.40 ENSDART00000064163
neurofilament, medium polypeptide b
chr4_-_4834347 0.40 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr11_+_34760628 0.40 ENSDART00000087216
si:dkey-202e22.2
chr4_+_43522680 0.40 ENSDART00000182252
si:dkeyp-53e4.4
chr2_-_56348727 0.40 ENSDART00000060745
ubiquitin A-52 residue ribosomal protein fusion product 1
chr11_-_1509773 0.40 ENSDART00000050762
phosphatase and actin regulator 3b
chr18_+_48423973 0.39 ENSDART00000184233
ENSDART00000147074
Fli-1 proto-oncogene, ETS transcription factor a
chr5_-_54672763 0.39 ENSDART00000159009
sperm associated antigen 8
chr10_-_42882215 0.39 ENSDART00000180580
ENSDART00000187374

chr9_-_53666031 0.39 ENSDART00000126314
protocadherin 8
chr17_+_51627209 0.39 ENSDART00000056886
zgc:113142
chr7_-_33960170 0.39 ENSDART00000180766
SKI family transcriptional corepressor 1a
chr17_-_29224908 0.39 ENSDART00000156288
si:dkey-28g23.6
chr14_+_24284756 0.38 ENSDART00000079164
kelch-like family member 3
chr7_+_59020972 0.38 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr3_-_60175470 0.38 ENSDART00000156597
si:ch73-364h19.1
chr6_+_2097690 0.37 ENSDART00000193770
transglutaminase 2b
chr19_+_43359075 0.36 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
Yes-related kinase
chr13_+_255067 0.36 ENSDART00000102505
forkhead box G1d
chr12_-_9294819 0.36 ENSDART00000003805
parathyroid hormone 1 receptor b
chr22_-_10121880 0.36 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr7_-_30174882 0.35 ENSDART00000110409
FERM domain containing 5
chr6_-_11768198 0.35 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr14_+_5385855 0.35 ENSDART00000031508
ladybird homeobox 2
chr20_-_45812144 0.35 ENSDART00000147897
ENSDART00000147637
fermitin family member 1
chr16_-_43344859 0.35 ENSDART00000058680
proteasome subunit alpha 2
chr25_+_11008419 0.35 ENSDART00000156589
major histocompatibility complex class I LIA
chr7_+_6652967 0.35 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr6_+_25257728 0.35 ENSDART00000162581
kynurenine aminotransferase 3
chr11_-_45138857 0.34 ENSDART00000166501
calcium activated nucleotidase 1b
chr5_+_46481586 0.34 ENSDART00000144973
versican a
chr23_-_3681026 0.34 ENSDART00000192128
ENSDART00000040086
protein kinase C and casein kinase substrate in neurons 1a
chr25_-_35360096 0.34 ENSDART00000154053
ENSDART00000171917
si:ch73-147o17.1
chr14_-_7137808 0.34 ENSDART00000054803
tRNA phosphotransferase 1
chr3_-_19368435 0.34 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr5_-_20205075 0.34 ENSDART00000051611
D-amino-acid oxidase, tandem duplicate 3
chr22_-_12160283 0.34 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr11_+_26476153 0.34 ENSDART00000103507
un-named sa1614
chr6_+_52350443 0.33 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr2_+_2223837 0.33 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr24_-_38657683 0.33 ENSDART00000154843
si:ch1073-164k15.3
chr1_+_6172786 0.33 ENSDART00000126468
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr4_+_22480169 0.33 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr12_+_31713239 0.33 ENSDART00000122379
hyaluronan binding protein 2
chr4_+_21129752 0.33 ENSDART00000169764
synaptotagmin Ia
chr15_-_21014270 0.33 ENSDART00000154019
si:ch211-212c13.10
chr3_+_25154078 0.32 ENSDART00000156973
si:ch211-256m1.8
chr17_+_38476300 0.32 ENSDART00000123298
StAR-related lipid transfer (START) domain containing 9
chr23_+_43255328 0.32 ENSDART00000102712
transglutaminase 2, C polypeptide A
chr22_-_10482253 0.32 ENSDART00000143164
asporin (LRR class 1)
chr18_-_46258612 0.32 ENSDART00000153930
si:dkey-244a7.1
chr5_+_11840905 0.32 ENSDART00000030444
tescalcin a
chr1_-_25966068 0.32 ENSDART00000137869
ENSDART00000134192
synaptopodin 2b
chr8_+_23521974 0.31 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr16_-_11798994 0.31 ENSDART00000135408
cornifelin
chr3_+_33341640 0.31 ENSDART00000186352
peptide YYa
chr6_-_46941245 0.31 ENSDART00000037875
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 1
chr5_+_36752943 0.31 ENSDART00000017138
exocyst complex component 3-like 2a
chr1_-_43915423 0.30 ENSDART00000181915
ENSDART00000113673
secretory calcium-binding phosphoprotein 5
chr14_-_858985 0.30 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr2_+_11685742 0.30 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr8_+_28259347 0.30 ENSDART00000110857
family with sequence similarity 212, member B
chr19_-_5699703 0.30 ENSDART00000082050
zgc:174904
chr2_-_27329667 0.30 ENSDART00000187490
thioredoxin related transmembrane protein 3a
chr19_+_43780970 0.30 ENSDART00000063870
ribosomal protein L11
chr15_-_47865063 0.30 ENSDART00000151600
H3 histone, family 3B.1
chr4_+_57881965 0.30 ENSDART00000162234
si:dkeyp-44b5.4
chr21_+_22840246 0.30 ENSDART00000151621
baculoviral IAP repeat containing 2
chr12_-_31794908 0.30 ENSDART00000105583
ENSDART00000153449
N-acetyltransferase 9 (GCN5-related, putative)
chr6_-_39270851 0.30 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b
chr11_+_41242644 0.30 ENSDART00000172008
paired box 7a
chr16_-_12173399 0.29 ENSDART00000142574
calsyntenin 3
chr15_+_45640906 0.29 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr23_+_26733232 0.29 ENSDART00000035080
zgc:158263
chr4_+_16715267 0.29 ENSDART00000143849
plakophilin 2
chr15_+_9327252 0.29 ENSDART00000144381
sarcoglycan, gamma
chr8_+_24745041 0.29 ENSDART00000148872
solute carrier family 16, member 4
chr17_-_36896560 0.29 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr4_-_12907826 0.29 ENSDART00000182923
methionine sulfoxide reductase B3
chr20_-_9760424 0.29 ENSDART00000104936
si:dkey-63j12.4
chr7_+_20471315 0.28 ENSDART00000173714
si:dkey-19b23.13
chr19_-_26869103 0.28 ENSDART00000089699
proline-rich transmembrane protein 1
chr23_-_20051369 0.28 ENSDART00000049836
biglycan b
chr18_+_24919614 0.28 ENSDART00000008638
repulsive guidance molecule family member a
chr19_+_156757 0.28 ENSDART00000167717
capping protein regulator and myosin 1 linker 1
chr2_+_20406399 0.28 ENSDART00000006817
ENSDART00000137848
palmdelphin a
chr10_-_35236949 0.28 ENSDART00000145804
yippee-like 2a
chr8_+_49778486 0.28 ENSDART00000131732
neurotrophic tyrosine kinase, receptor, type 2a
chr7_+_39634873 0.28 ENSDART00000114774
protein tyrosine phosphatase, non-receptor type 5
chr19_-_10810006 0.28 ENSDART00000151157
si:dkey-3n22.9
chr9_-_1703761 0.28 ENSDART00000144822
ENSDART00000137210
ENSDART00000135273
heterogeneous nuclear ribonucleoprotein A3
chr5_+_40485503 0.28 ENSDART00000051055
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr20_+_53441935 0.28 ENSDART00000175214
apolipoprotein Bb, tandem duplicate 2
chr5_-_12219572 0.27 ENSDART00000167834
nitric oxide synthase 1 (neuronal)
chr19_+_12237945 0.27 ENSDART00000190034
grainyhead-like transcription factor 2b
chr4_-_9909371 0.27 ENSDART00000102656
si:dkey-22l11.6
chr7_-_71829649 0.27 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr4_-_1908179 0.27 ENSDART00000139586
anoctamin 6
chr8_-_4596662 0.27 ENSDART00000138199
septin 5a
chr4_-_76488854 0.27 ENSDART00000132323
finTRIM family, member 51
chr1_+_45663727 0.26 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trafficking protein particle complex 5
chr1_+_52560549 0.26 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr6_-_54815886 0.26 ENSDART00000180793
ENSDART00000007498
troponin I type 1b (skeletal, slow)
chr18_-_34549721 0.26 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr8_-_12867434 0.26 ENSDART00000081657
solute carrier family 2 (facilitated glucose transporter), member 6
chr22_+_7738966 0.26 ENSDART00000147073
si:ch73-44m9.5
chr8_-_30979494 0.26 ENSDART00000138959
si:ch211-251j10.3
chr11_-_2131280 0.26 ENSDART00000008409
calcium binding and coiled-coil domain 1b
chr4_+_72723304 0.25 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
RAB3A interacting protein (rabin3)

Network of associatons between targets according to the STRING database.

First level regulatory network of alx4a+alx4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.3 0.8 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.2 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 0.6 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.6 GO:0098725 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.2 0.7 GO:0097242 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.2 0.5 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.9 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:0070169 positive regulation of bone mineralization(GO:0030501) positive regulation of ossification(GO:0045778) positive regulation of biomineral tissue development(GO:0070169)
0.1 0.4 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.1 0.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 0.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.1 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.3 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.3 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 0.3 GO:0055130 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.3 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 0.2 GO:1903011 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.2 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.5 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 0.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.4 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 0.3 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.5 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.2 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.8 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.4 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 2.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.4 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.2 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.2 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 0.1 GO:0032602 chemokine production(GO:0032602) negative T cell selection(GO:0043383) thymocyte migration(GO:0072679)
0.0 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.3 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.6 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0006096 glycolytic process(GO:0006096)
0.0 0.1 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.1 GO:0001881 receptor recycling(GO:0001881)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.0 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.0 0.3 GO:0007631 feeding behavior(GO:0007631)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.2 GO:0006801 superoxide metabolic process(GO:0006801)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.4 GO:0005883 neurofilament(GO:0005883)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.3 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.4 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.2 2.0 GO:0016936 galactoside binding(GO:0016936)
0.2 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 2.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.5 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 0.9 GO:0008430 selenium binding(GO:0008430)
0.2 0.5 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.1 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.3 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.4 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.5 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 0.2 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0070915 bioactive lipid receptor activity(GO:0045125) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.8 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.3 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport