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PRJNA195909:zebrafish embryo and larva development

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Results for alx1

Z-value: 0.86

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Transcription factors associated with alx1

Gene Symbol Gene ID Gene Info
ENSDARG00000062824 ALX homeobox 1
ENSDARG00000110530 ALX homeobox 1
ENSDARG00000115230 ALX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx1dr11_v1_chr18_+_16246806_16246806-0.117.9e-01Click!

Activity profile of alx1 motif

Sorted Z-values of alx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 1.25 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr2_+_50608099 0.92 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr19_-_5103141 0.75 ENSDART00000150952
triosephosphate isomerase 1a
chr20_-_45060241 0.70 ENSDART00000185227
kelch-like family member 29
chr7_-_51773166 0.66 ENSDART00000054591
bone morphogenetic protein 15
chr1_-_43905252 0.64 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr2_+_37227011 0.64 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr8_+_45334255 0.61 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr12_-_14143344 0.60 ENSDART00000152742
bucky ball 2-like
chr16_+_39159752 0.54 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr19_-_5103313 0.53 ENSDART00000037007
triosephosphate isomerase 1a
chr11_+_44804685 0.51 ENSDART00000163660
striatin, calmodulin binding protein
chr4_-_13580348 0.49 ENSDART00000067160
opsin 1 (cone pigments), short-wave-sensitive 1
chr21_-_14251306 0.48 ENSDART00000114715
ENSDART00000181380
mannosidase, alpha, class 1B, member 1a
chr9_+_29548195 0.47 ENSDART00000176057
ring finger protein 17
chr20_-_9436521 0.47 ENSDART00000133000
zgc:101840
chr20_+_32523576 0.46 ENSDART00000147319
Scm polycomb group protein like 4
chr15_+_47903864 0.44 ENSDART00000063835
orthodenticle homolog 5
chr17_-_41798856 0.44 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr22_-_17653143 0.43 ENSDART00000089171
histocompatibility (minor) HA-1 b
chr23_+_20563779 0.43 ENSDART00000146008
CaM kinase-like vesicle-associated, like
chr22_+_17828267 0.42 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr15_-_34408777 0.42 ENSDART00000139934
alkylglycerol monooxygenase
chr22_+_34784075 0.41 ENSDART00000167538
ligand dependent nuclear receptor corepressor
chr21_-_14174786 0.40 ENSDART00000145366
whirlin a
chr23_-_27571667 0.40 ENSDART00000008174
phosphofructokinase, muscle a
chr20_-_45062514 0.40 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr21_+_25777425 0.39 ENSDART00000021620
claudin d
chr10_-_25217347 0.38 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr23_-_32157865 0.38 ENSDART00000000876
nuclear receptor subfamily 4, group A, member 1
chr21_-_32060993 0.38 ENSDART00000131651
si:ch211-160j14.2
chr21_+_3093419 0.37 ENSDART00000162520
SHC adaptor protein 3
chr14_+_44860335 0.37 ENSDART00000091620
ENSDART00000173043
ENSDART00000091625
ATPase phospholipid transporting 8A1
chr16_+_47207691 0.36 ENSDART00000062507
islet cell autoantigen 1
chr13_+_38430466 0.36 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr5_+_57924611 0.36 ENSDART00000050949
B-cell translocation gene 4
chr15_-_6247775 0.36 ENSDART00000148350
Down syndrome cell adhesion molecule b
chr5_-_20491198 0.35 ENSDART00000183051
ENSDART00000144232
FIC domain containing
chr11_-_40418975 0.35 ENSDART00000086296
tripartite motif containing 62
chr25_+_7504314 0.35 ENSDART00000163231
interferon induced transmembrane protein 5
chr24_-_7697274 0.34 ENSDART00000186077
synaptotagmin Vb
chr10_+_16911951 0.34 ENSDART00000164933
unc-13 homolog B
chr4_-_14315855 0.34 ENSDART00000133325
neural EGFL like 2b
chr14_-_8940499 0.33 ENSDART00000129030
zgc:153681
chr9_+_50001746 0.33 ENSDART00000058892
solute carrier family 38, member 11
chr15_-_33172246 0.33 ENSDART00000158666
neurobeachin b
chr11_+_35171406 0.33 ENSDART00000110839
MON1 secretory trafficking family member A
chr19_-_5865766 0.33 ENSDART00000191007

chr18_+_1703984 0.32 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr4_+_21129752 0.32 ENSDART00000169764
synaptotagmin Ia
chr16_+_27349585 0.32 ENSDART00000142573
nuclear receptor subfamily 4, group A, member 3
chr19_+_10339538 0.31 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr21_-_36453594 0.31 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr7_+_25126629 0.31 ENSDART00000077217
zgc:101765
chr17_+_26722904 0.31 ENSDART00000114927
NRDE-2, necessary for RNA interference, domain containing
chr17_-_40956035 0.31 ENSDART00000124715
si:dkey-16j16.4
chr24_+_1023839 0.30 ENSDART00000082526
zgc:111976
chr23_+_28092083 0.29 ENSDART00000053958
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr1_+_18811679 0.29 ENSDART00000078610
solute carrier family 25, member 51a
chr10_-_21362071 0.29 ENSDART00000125167
avidin
chr15_-_44601331 0.29 ENSDART00000161514
zgc:165508
chr25_+_33849647 0.29 ENSDART00000121449
RAR-related orphan receptor A, paralog a
chr10_-_11385155 0.29 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr19_-_5805923 0.29 ENSDART00000134340
si:ch211-264f5.8
chr6_-_50203682 0.29 ENSDART00000083999
ENSDART00000143050
RALY heterogeneous nuclear ribonucleoprotein
chr2_-_42871286 0.29 ENSDART00000087823
adenylate cyclase 8 (brain)
chr5_-_13206878 0.28 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr11_+_12052791 0.28 ENSDART00000158479
si:ch211-156l18.8
chr5_-_28915130 0.28 ENSDART00000078592
neural proliferation, differentiation and control, 1b
chr21_-_25722834 0.28 ENSDART00000101208
abhydrolase domain containing 11
chr16_-_28658341 0.28 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr9_+_12887491 0.27 ENSDART00000102386
si:ch211-167j6.4
chr11_+_31864921 0.27 ENSDART00000180252
diaphanous-related formin 3
chr16_-_34401412 0.27 ENSDART00000054020
human immunodeficiency virus type I enhancer binding protein 3b
chr25_-_27564205 0.27 ENSDART00000157319
hyaluronoglucosaminidase 4
chr22_-_17652914 0.27 ENSDART00000138483
si:ch73-243b8.4
chr22_+_4488454 0.27 ENSDART00000170620
cortexin 1
chr3_+_32553714 0.27 ENSDART00000165638
paired box 10
chr9_-_14683574 0.27 ENSDART00000144022
par-3 family cell polarity regulator beta b
chr7_-_71389375 0.26 ENSDART00000128928

chr21_+_34088377 0.26 ENSDART00000170070
myotubularin related protein 1b
chr8_+_11425048 0.26 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr12_-_13549538 0.26 ENSDART00000133895
GH3 domain containing
chr6_+_29693492 0.26 ENSDART00000114172
phosphodiesterase 6D, cGMP-specific, rod, delta
chr24_+_12835935 0.26 ENSDART00000114762
nanog homeobox
chr6_+_9870192 0.26 ENSDART00000150894
si:ch211-222n4.6
chr24_+_16547035 0.26 ENSDART00000164319
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr21_-_18993110 0.26 ENSDART00000144086
si:ch211-222n4.6
chr18_-_16801033 0.26 ENSDART00000100100
adrenomedullin b
chr13_+_38817871 0.26 ENSDART00000187708
collagen, type XIX, alpha 1
chr17_-_200316 0.26 ENSDART00000190561

chr24_-_31452875 0.25 ENSDART00000187381
ENSDART00000185128
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr6_-_46861676 0.25 ENSDART00000188712
ENSDART00000190148
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr20_-_40755614 0.25 ENSDART00000061247
connexin 32.3
chr5_+_27137473 0.25 ENSDART00000181833
unc-5 netrin receptor Db
chr23_+_40460333 0.25 ENSDART00000184658
SOGA family member 3b
chr18_-_43884044 0.25 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr2_+_29997043 0.25 ENSDART00000139566
ENSDART00000151848
RNA binding motif protein 33b
chr15_+_31344472 0.24 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr7_+_23292133 0.24 ENSDART00000134489
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr5_+_51594209 0.24 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
creatine kinase, mitochondrial 2b (sarcomeric)
chr10_-_32494499 0.24 ENSDART00000129395
UV radiation resistance associated gene
chr6_-_30839763 0.24 ENSDART00000154228
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr9_+_45428041 0.24 ENSDART00000193087
adenosine deaminase, RNA-specific, B1b
chr18_-_399554 0.24 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
chr23_+_24272421 0.24 ENSDART00000029974
chloride channel K
chr9_+_29548630 0.24 ENSDART00000132295
ring finger protein 17
chr12_-_30358836 0.24 ENSDART00000152878
tudor domain containing 1
chr22_+_39096911 0.24 ENSDART00000157127
ENSDART00000153841
LIM and cysteine-rich domains 1
chr24_+_17068724 0.24 ENSDART00000191137
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr7_+_22313533 0.24 ENSDART00000123457
si:dkey-11f12.2
chr18_+_15644559 0.23 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr12_-_6818676 0.23 ENSDART00000106391
protocadherin-related 15b
chr21_-_39177564 0.23 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr21_-_16632808 0.23 ENSDART00000172645
unc-5 netrin receptor Da
chr9_+_34641237 0.23 ENSDART00000133996
short stature homeobox
chr16_-_46579936 0.23 ENSDART00000166143
ENSDART00000127212
si:dkey-152b24.6
chr25_-_13381854 0.23 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr2_-_3403020 0.23 ENSDART00000092741
synaptosomal-associated protein, 47
chr10_-_32494304 0.23 ENSDART00000028161
UV radiation resistance associated gene
chr2_-_15324837 0.23 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr10_+_518546 0.23 ENSDART00000128275
neuropeptide FF receptor 1 like 3
chr24_-_5713799 0.23 ENSDART00000137293
deleted in autism 1b
chr25_+_5604512 0.23 ENSDART00000042781
plexin b2b
chr14_+_30773764 0.22 ENSDART00000186961
atlastin 3
chr13_-_32726178 0.22 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr16_+_2820340 0.22 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
chr9_-_50001606 0.22 ENSDART00000161648
ENSDART00000168514
sodium channel, voltage-gated, type I, alpha
chr25_+_3035384 0.22 ENSDART00000184219
ENSDART00000149360
mannose phosphate isomerase
chr1_+_18920213 0.22 ENSDART00000193777
ring finger protein 38
chr6_-_12172424 0.22 ENSDART00000109344
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr15_+_44366556 0.22 ENSDART00000133449
guanylate cyclase 1 soluble subunit alpha 2
chr19_-_30510259 0.22 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
BCL2 associated athanogene 6, like
chr7_-_54217547 0.22 ENSDART00000162777
ENSDART00000188268
ENSDART00000165875
casein kinase 1, gamma 1
chr1_+_21937201 0.22 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr2_+_42871831 0.22 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr10_-_27049170 0.22 ENSDART00000143451
cornichon family AMPA receptor auxiliary protein 2
chr21_-_28640316 0.21 ENSDART00000128237
neuregulin 2a
chr5_+_61301525 0.21 ENSDART00000128773
double C2-like domains, beta
chr7_+_26649319 0.21 ENSDART00000173823
ENSDART00000101053
tumor protein p53 inducible protein 11a
chr13_+_23095228 0.21 ENSDART00000189068
ENSDART00000188624
phosphoinositide-3-kinase adaptor protein 1
chr24_+_5208171 0.21 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
chr7_+_48761875 0.21 ENSDART00000003690
aggrecan a
chr12_+_45677293 0.21 ENSDART00000152850
ENSDART00000153047
si:ch73-111m19.2
chr5_+_29794058 0.21 ENSDART00000045410
Thy-1 cell surface antigen
chr24_+_5912635 0.21 ENSDART00000153736
Pim proto-oncogene, serine/threonine kinase, related 63
chr16_-_16120941 0.21 ENSDART00000131227
ankyrin repeat and IBR domain containing 1b
chr5_-_61797220 0.21 ENSDART00000079855
im:7138535
chr2_+_20332044 0.21 ENSDART00000112131
phospholipid phosphatase related 4a
chr22_-_10486477 0.21 ENSDART00000184366
asporin (LRR class 1)
chr2_+_38002717 0.20 ENSDART00000139564
DDB1 and CUL4 associated factor 8
chr8_-_21142550 0.20 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
carnitine palmitoyltransferase 2
chr12_+_22407852 0.20 ENSDART00000178840
high density lipoprotein binding protein b
chr3_-_25268751 0.20 ENSDART00000139423
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr4_+_11723852 0.20 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr8_-_25034411 0.20 ENSDART00000135973
nuclear transcription factor Y, alpha, like
chr12_-_30359498 0.20 ENSDART00000152981
ENSDART00000189988
tudor domain containing 1
chr22_+_20427170 0.20 ENSDART00000136744
forkhead box Q2
chr12_-_6880694 0.20 ENSDART00000171846
protocadherin-related 15b
chr19_-_32710922 0.20 ENSDART00000004034
hippocalcin
chr22_-_24818066 0.20 ENSDART00000143443
vitellogenin 6
chr10_-_21362320 0.19 ENSDART00000189789
avidin
chr11_-_1550709 0.19 ENSDART00000110097
si:ch73-303b9.1
chr12_-_30359031 0.19 ENSDART00000192628
tudor domain containing 1
chr19_+_41464870 0.19 ENSDART00000102778
distal-less homeobox 6a
chr22_-_14739491 0.19 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr13_+_40501455 0.19 ENSDART00000114985
heparanase 2
chr23_-_36823932 0.19 ENSDART00000142305
homeodomain interacting protein kinase 1a
chr21_-_36453417 0.19 ENSDART00000018350
CCR4-NOT transcription complex, subunit 8
chr23_+_45584223 0.19 ENSDART00000149367
si:ch73-290k24.5
chr2_+_6963296 0.19 ENSDART00000147146
discoidin domain receptor tyrosine kinase 2b
chr4_-_12766418 0.19 ENSDART00000024312
deoxyribose-phosphate aldolase (putative)
chr23_-_30954738 0.19 ENSDART00000188996
oxysterol binding protein-like 2a
chr15_+_22867174 0.19 ENSDART00000035812
glutamate receptor, ionotropic, kainate 4
chr10_-_31015535 0.19 ENSDART00000146116
pannexin 3
chr5_+_31283576 0.19 ENSDART00000133743
calcium/calmodulin-dependent protein kinase kinase 1, alpha a
chr21_+_34088110 0.19 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr1_+_35985813 0.19 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr8_+_25145464 0.19 ENSDART00000136505
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr5_+_35786141 0.19 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr8_+_3820134 0.18 ENSDART00000122454
citron rho-interacting serine/threonine kinase b
chr12_-_33579873 0.18 ENSDART00000184661
tudor and KH domain containing
chr15_-_9272328 0.18 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr22_-_20924564 0.18 ENSDART00000100642
ENSDART00000032770
elongation factor RNA polymerase II
chr14_-_2933185 0.18 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr3_+_25154078 0.18 ENSDART00000156973
si:ch211-256m1.8
chr2_+_25198648 0.18 ENSDART00000110922
protein phosphatase 2, regulatory subunit B'', alpha
chr10_+_6010570 0.18 ENSDART00000190025
ENSDART00000163680
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr5_+_58421536 0.18 ENSDART00000173410
coiled-coil domain containing 15
chr6_-_12900154 0.18 ENSDART00000080408
ENSDART00000150887
islet cell autoantigen 1-like
chr20_+_16639848 0.18 ENSDART00000063944
ENSDART00000152359
transmembrane protein 30Ab
chr23_-_32162810 0.18 ENSDART00000155905
nuclear receptor subfamily 4, group A, member 1
chr19_-_977849 0.17 ENSDART00000172303

chr25_+_31227747 0.17 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr14_+_35428152 0.17 ENSDART00000172597
synaptotagmin-like 4
chr13_-_31017960 0.17 ENSDART00000145287
WDFY family member 4
chr8_+_41037541 0.17 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr21_-_22737228 0.17 ENSDART00000151366
F-box protein 40, tandem duplicate 2
chr25_+_31277415 0.17 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr18_-_1185772 0.17 ENSDART00000143245
neuroplastin b

Network of associatons between targets according to the STRING database.

First level regulatory network of alx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.7 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.2 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.3 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.3 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.4 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 0.1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:1900186 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.3 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.1 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.2 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.1 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.0 0.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.6 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.1 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.0 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.0 0.2 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0071546 pi-body(GO:0071546)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.5 GO:0009374 biotin binding(GO:0009374)
0.1 0.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.3 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases