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PRJNA195909:zebrafish embryo and larva development

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Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 0.81

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Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Gene Symbol Gene ID Gene Info
ENSDARG00000107408 transcription factor 4
ENSDARG00000045131 inhibitor of DNA binding 4
ENSDARG00000017078 mesoderm posterior aa
ENSDARG00000030347 mesoderm posterior ba
ENSDARG00000068761 mesoderm posterior ab
ENSDARG00000097947 mesoderm posterior bb
ENSDARG00000110553 mesoderm posterior ba
ENSDARG00000114890 mesoderm posterior aa

Activity-expression correlation:

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_58751504 1.49 ENSDART00000024185
zgc:56231
chr21_-_34261677 1.39 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr22_+_17828267 1.07 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr23_+_553396 1.01 ENSDART00000034707
LSM family member 14B
chr12_+_13091842 0.97 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr6_+_40523370 0.97 ENSDART00000033819
protein kinase C, delta a
chr12_-_23365737 0.96 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr2_+_27855102 0.94 ENSDART00000150330
bucky ball
chr2_+_27855346 0.88 ENSDART00000175159
ENSDART00000192645
bucky ball
chr21_-_30293224 0.85 ENSDART00000101051
stem-loop binding protein 2
chr15_+_38299385 0.82 ENSDART00000142403
si:dkey-24p1.6
chr2_-_50225411 0.82 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr17_-_38887424 0.73 ENSDART00000141177
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr10_-_25217347 0.73 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr16_-_42066523 0.72 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr23_+_39854566 0.69 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr18_-_25771553 0.68 ENSDART00000103046
zgc:162879
chr15_+_38299563 0.68 ENSDART00000099375
si:dkey-24p1.6
chr22_+_17261801 0.68 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr14_+_15155684 0.67 ENSDART00000167966
zgc:158852
chr3_-_21061931 0.67 ENSDART00000036741
family with sequence similarity 57, member Ba
chr14_-_35672890 0.66 ENSDART00000074710
platelet derived growth factor c
chr12_-_10512911 0.65 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr3_+_17456428 0.65 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
chr1_+_24387659 0.65 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr6_+_10333920 0.64 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr6_+_153146 0.62 ENSDART00000097468
zinc finger, GATA-like protein 1
chr12_-_17810543 0.62 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr8_+_45334255 0.61 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr1_-_34450622 0.61 ENSDART00000083736
LIM domain 7b
chr11_-_43473824 0.60 ENSDART00000179561
transmembrane protein 63Bb
chr3_+_42923275 0.59 ENSDART00000168228
transmembrane protein 184a
chr3_+_37827373 0.59 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr5_-_15494164 0.58 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr4_-_20177868 0.57 ENSDART00000003621
siaz-interacting nuclear protein
chr17_+_1360192 0.57 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr13_+_31716820 0.57 ENSDART00000034745
protein kinase C, eta, a
chr25_-_17587785 0.55 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr23_-_32156278 0.55 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr7_-_48251234 0.55 ENSDART00000024062
ENSDART00000098904
cytoplasmic polyadenylation element binding protein 1b
chr15_+_29025090 0.55 ENSDART00000131755
si:ch211-137a8.2
chr10_+_40324395 0.55 ENSDART00000147205
glycolipid transfer protein b
chr7_+_57089354 0.55 ENSDART00000140702
secretory carrier membrane protein 2, like
chr21_-_4764120 0.54 ENSDART00000129355
ENSDART00000102643
calmodulin regulated spectrin-associated protein 1a
chr23_+_28128453 0.54 ENSDART00000182618
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr14_-_46198373 0.54 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr5_-_23715861 0.53 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr21_-_43666420 0.52 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr2_-_47620806 0.52 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr15_+_29472065 0.52 ENSDART00000154343
glycerophosphodiester phosphodiesterase domain containing 5b
chr7_-_55648336 0.52 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr5_-_32338866 0.51 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_5610514 0.51 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr16_-_47381519 0.51 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr15_+_29024895 0.51 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr8_+_9699111 0.51 ENSDART00000111853
GRIP1 associated protein 1
chr3_+_56699187 0.50 ENSDART00000168133
ring finger protein 213a
chr15_-_43164591 0.50 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr7_+_67699009 0.50 ENSDART00000192810
zgc:162592
chr17_-_36860988 0.50 ENSDART00000154981
SUMO1/sentrin specific peptidase 6b
chr25_-_12203952 0.49 ENSDART00000158204
ENSDART00000091727
neurotrophic tyrosine kinase, receptor, type 3a
chr11_-_25853212 0.49 ENSDART00000145655
transmembrane protein 51b
chr13_-_21672131 0.48 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr23_+_43684494 0.47 ENSDART00000149878
OTU deubiquitinase 4
chr9_-_32912638 0.47 ENSDART00000110582
family with sequence similarity 160, member A2
chr6_+_45692026 0.46 ENSDART00000164759
contactin 4
chr2_+_1988036 0.46 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr1_+_18811679 0.46 ENSDART00000078610
solute carrier family 25, member 51a
chr10_+_1052591 0.46 ENSDART00000123405
unc-5 netrin receptor C
chr14_+_22457230 0.46 ENSDART00000019296
growth differentiation factor 9
chr3_-_29910547 0.45 ENSDART00000151501
si:dkey-151m15.5
chr13_-_9442942 0.45 ENSDART00000138833
glutaredoxin, cysteine rich 1
chr15_+_784149 0.45 ENSDART00000155114
zinc finger protein 970
chr4_-_20232974 0.45 ENSDART00000193353
serine/threonine kinase 38 like
chr13_-_39254 0.45 ENSDART00000093222
general transcription factor IIA, 1-like
chr1_-_18811517 0.44 ENSDART00000142026
si:dkey-167i21.2
chr12_+_46543572 0.44 ENSDART00000167510
HID1 domain containing b
chr22_+_23430688 0.44 ENSDART00000160457
DENN/MADD domain containing 1B
chr5_+_44846434 0.43 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr14_-_21618005 0.43 ENSDART00000043162
receptor accessory protein 2
chr4_-_65323874 0.43 ENSDART00000175271
ENSDART00000187913

chr8_+_13364950 0.43 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr23_+_19594608 0.43 ENSDART00000134865
sarcolemma associated protein b
chr10_-_31805923 0.43 ENSDART00000077785
vacuolar protein sorting 26 homolog B, like
chr2_+_25658112 0.42 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr6_-_29305132 0.42 ENSDART00000132456
basic, immunoglobulin-like variable motif containing
chr17_-_15029639 0.42 ENSDART00000142941
endoplasmic reticulum oxidoreductase alpha
chr13_-_24877577 0.42 ENSDART00000182705
K(lysine) acetyltransferase 6B
chr19_+_14454306 0.42 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr23_-_26488622 0.41 ENSDART00000168052
ENSDART00000169088
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr4_-_858434 0.41 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr18_+_9493720 0.41 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_-_34269066 0.40 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr17_-_25331439 0.40 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr7_+_67699178 0.40 ENSDART00000160086
zgc:162592
chr2_+_6253246 0.39 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr10_+_31809226 0.39 ENSDART00000087898
forkhead box O1 b
chr11_+_6882362 0.39 ENSDART00000144181
kelch-like family member 26
chr5_-_33236637 0.39 ENSDART00000085512
ENSDART00000144694
KN motif and ankyrin repeat domains 1b
chr11_+_31730680 0.39 ENSDART00000145497
diaphanous-related formin 3
chr6_+_10338554 0.39 ENSDART00000186936
cordon-bleu WH2 repeat protein-like 1a
chr22_-_24992532 0.39 ENSDART00000102751
si:dkey-179j5.5
chr5_-_65662996 0.38 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr4_-_17263210 0.38 ENSDART00000147853
lymphoid-restricted membrane protein
chr14_-_33278084 0.37 ENSDART00000132850
START domain containing 14
chr3_-_34586403 0.37 ENSDART00000151515
septin 9a
chr21_-_21178410 0.37 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
FtsJ RNA methyltransferase homolog 1
chr12_-_47601845 0.37 ENSDART00000169548
ENSDART00000182889
regulator of G protein signaling 7b
chr13_+_28618086 0.37 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr7_+_69449814 0.36 ENSDART00000109644
CTD nuclear envelope phosphatase 1b
chr13_+_2448251 0.36 ENSDART00000188361
ARFGEF family member 3
chr4_-_14328997 0.36 ENSDART00000091151
neural EGFL like 2b
chr17_-_15029258 0.36 ENSDART00000168332
ENSDART00000012877
ENSDART00000109190
endoplasmic reticulum oxidoreductase alpha
chr17_-_11151655 0.36 ENSDART00000156383

chr5_-_23696926 0.36 ENSDART00000021462
ring finger protein 128a
chr16_-_12723738 0.35 ENSDART00000080414
SH3 domain binding kinase family, member 3
chr10_+_34001444 0.35 ENSDART00000149934
klotho
chr4_-_4795205 0.35 ENSDART00000039313
zgc:162331
chr16_-_42056137 0.35 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr6_-_12912606 0.35 ENSDART00000164640
islet cell autoantigen 1-like
chr20_-_14114078 0.34 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr11_+_6902946 0.34 ENSDART00000144006
CREB regulated transcription coactivator 1b
chr5_-_31772559 0.34 ENSDART00000183879
family with sequence similarity 102, member Ab
chr8_+_2642384 0.34 ENSDART00000143242
nuclear apoptosis inducing factor 1
chr14_-_6402769 0.34 ENSDART00000121552
solute carrier family 44 (choline transporter), member 1b
chr8_+_28724692 0.33 ENSDART00000140115
coiled-coil serine-rich protein 1
chr16_+_28881235 0.33 ENSDART00000146525
chromatin target of PRMT1b
chr18_-_50845804 0.33 ENSDART00000158517
si:cabz01113374.3
chr16_+_51462620 0.33 ENSDART00000169443
solute carrier family 9 member A1
chr13_-_31025505 0.33 ENSDART00000137709
WDFY family member 4
chr11_-_28050559 0.33 ENSDART00000136859
endothelin converting enzyme 1
chr17_+_24936059 0.33 ENSDART00000082438
discs, large (Drosophila) homolog-associated protein 2a
chr5_-_31773208 0.33 ENSDART00000137556
ENSDART00000122066
family with sequence similarity 102, member Ab
chr1_-_40341306 0.33 ENSDART00000190649
mastermind-like transcriptional coactivator 3
chr23_-_874418 0.33 ENSDART00000133906
RNA binding motif protein 10
chr18_-_26675699 0.33 ENSDART00000113280
si:ch211-69m14.1
chr8_+_44613135 0.33 ENSDART00000063392
LSM1, U6 small nuclear RNA associated
chr8_-_4097722 0.33 ENSDART00000135006
cut-like homeobox 2b
chr5_+_44846280 0.32 ENSDART00000084370
KN motif and ankyrin repeat domains 1a
chr22_-_5171829 0.32 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr21_-_39546737 0.32 ENSDART00000006971
septin 4a
chr13_-_24906307 0.32 ENSDART00000148191
ENSDART00000189810
K(lysine) acetyltransferase 6B
chr16_-_25233515 0.32 ENSDART00000058943
zgc:110182
chr16_+_41060161 0.32 ENSDART00000141130
SREBF chaperone
chr4_+_14981854 0.32 ENSDART00000067046
cation/H+ exchanger protein 1
chr6_+_29305190 0.31 ENSDART00000078647
si:ch211-201h21.5
chr8_+_41048501 0.31 ENSDART00000123288
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr13_-_36911118 0.31 ENSDART00000048739
tripartite motif containing 9
chr7_-_36113098 0.31 ENSDART00000064913
fat mass and obesity associated
chr23_-_18057270 0.31 ENSDART00000173385
zgc:92287
chr10_-_38468847 0.31 ENSDART00000133914
glycerophosphodiester phosphodiesterase domain containing 5a
chr6_+_60112200 0.31 ENSDART00000008243
PRELI domain containing 3
chr5_+_57924611 0.31 ENSDART00000050949
B-cell translocation gene 4
chr7_+_61184551 0.30 ENSDART00000190788
zgc:194930
chr12_+_23866368 0.30 ENSDART00000188652
ENSDART00000192478
supervillin a
chr16_+_53387085 0.30 ENSDART00000154223
ENSDART00000101404
kinesin family member 13A
chr11_-_18800299 0.30 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr9_-_28990649 0.30 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr21_-_2287589 0.30 ENSDART00000161554
si:ch73-299h12.4
chr3_-_33494163 0.30 ENSDART00000020342
small G protein signaling modulator 3
chr22_-_22164338 0.30 ENSDART00000183840
cell division cycle 34 homolog (S. cerevisiae) a
chr14_+_50937757 0.29 ENSDART00000163865
ring finger protein 44
chr20_-_13625588 0.29 ENSDART00000078893
synaptotagmin-like 3
chr23_+_2728095 0.29 ENSDART00000066086
zgc:114123
chr5_-_69316142 0.29 ENSDART00000157238
ENSDART00000144570
smoothelin b
chr7_+_69187585 0.29 ENSDART00000160499
ENSDART00000166258
MARVEL domain containing 3
chr4_+_11690923 0.29 ENSDART00000150624
muskelin 1, intracellular mediator containing kelch motifs
chr18_-_12612699 0.29 ENSDART00000090335
homeodomain interacting protein kinase 2
chr5_+_20030414 0.29 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
small G protein signaling modulator 1a
chr20_-_164300 0.29 ENSDART00000183354
si:ch211-241j12.3
chr18_+_8917766 0.28 ENSDART00000145226
si:ch211-233h19.2
chr1_-_31105376 0.28 ENSDART00000132466
protein phosphatase 1 regulatory subunit 9A-like B
chr7_+_24523017 0.28 ENSDART00000077047
bloodthirsty-related gene family, member 9
chr7_+_47243564 0.28 ENSDART00000098942
ENSDART00000162237
zinc finger protein 507
chr11_-_18283886 0.28 ENSDART00000019248
STIM activating enhance
chr5_-_11573490 0.28 ENSDART00000109577

chr2_+_21309272 0.28 ENSDART00000141322
zinc finger and BTB domain containing 47a
chr5_-_37047147 0.28 ENSDART00000097712
ENSDART00000158974
finTRIM family, member 99
chr4_-_277081 0.28 ENSDART00000166174
si:ch73-252i11.1
chr12_-_35393211 0.28 ENSDART00000137139
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr1_+_51391082 0.28 ENSDART00000063936
autophagy related 4D, cysteine peptidase a
chr9_+_38502524 0.27 ENSDART00000087229
leishmanolysin-like (metallopeptidase M8 family)
chr7_+_1442059 0.27 ENSDART00000173391
si:cabz01090193.1
chr14_-_7409364 0.27 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr18_+_13248956 0.27 ENSDART00000080709
phospholipase C, gamma 2
chr8_-_13735572 0.27 ENSDART00000139642
si:dkey-258f14.7
chr10_+_29771256 0.27 ENSDART00000193195
hypoxia up-regulated 1
chr2_+_51796441 0.27 ENSDART00000165151
crystallin, gamma N1
chr13_-_28610965 0.27 ENSDART00000043156
cytochrome P450, family 17, subfamily A, polypeptide 1
chr8_+_18555559 0.27 ENSDART00000149523
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr2_+_24868010 0.27 ENSDART00000078838
RAB3A, member RAS oncogene family, a
chr12_+_32199651 0.27 ENSDART00000153027
si:ch211-277e21.1
chr10_+_37173029 0.27 ENSDART00000136510
kinase suppressor of ras 1a
chr16_-_25380903 0.27 ENSDART00000086375
ENSDART00000188587
ADNP homeobox 2a
chr2_-_15040345 0.27 ENSDART00000109657
si:dkey-10f21.4
chr13_+_7578111 0.27 ENSDART00000175431
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr7_+_25221757 0.26 ENSDART00000173551
exocyst complex component 6B
chr25_+_7492663 0.26 ENSDART00000166496
catalase
chr19_-_18127808 0.26 ENSDART00000108627
sorting nexin 10a
chr2_-_20715094 0.26 ENSDART00000155439
dual specificity phosphatase 12

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 0.7 GO:0030237 female sex determination(GO:0030237)
0.1 2.5 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.9 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.5 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.4 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.5 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 0.3 GO:0042245 RNA repair(GO:0042245)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 1.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.1 1.1 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0090008 hypoblast development(GO:0090008)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.5 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.2 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.5 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.6 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.2 GO:0036135 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.4 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.7 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.3 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 0.1 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.6 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0001840 neural plate development(GO:0001840)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.8 GO:0048885 neuromast deposition(GO:0048885)
0.0 0.7 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.1 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0010990 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.4 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0043420 anthranilate metabolic process(GO:0043420)
0.0 0.7 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:1900026 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0008585 female gonad development(GO:0008585)
0.0 0.1 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 1.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.2 GO:0032350 regulation of hormone metabolic process(GO:0032350)
0.0 0.1 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0046688 response to copper ion(GO:0046688)
0.0 0.0 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.1 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.0 0.6 GO:0048599 oocyte development(GO:0048599)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 1.2 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.0 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.2 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.0 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.1 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.2 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.0 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.0 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0071896 protein localization to adherens junction(GO:0071896)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 GO:0033391 chromatoid body(GO:0033391)
0.2 1.8 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.0 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005948 acetolactate synthase complex(GO:0005948)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.0 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 2.8 GO:0043296 apical junction complex(GO:0043296)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.6 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 1.1 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 0.6 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 2.5 GO:0032190 acrosin binding(GO:0032190)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.6 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.9 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.4 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.2 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.5 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.6 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003984 acetolactate synthase activity(GO:0003984)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.7 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0004096 catalase activity(GO:0004096)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.0 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.1 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.6 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0070628 lysine-acetylated histone binding(GO:0070577) proteasome binding(GO:0070628)
0.0 0.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.5 GO:0015296 anion:cation symporter activity(GO:0015296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis