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PRJNA195909:zebrafish embryo and larva development

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Results for CABZ01093502.2

Z-value: 0.36

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Transcription factors associated with CABZ01093502.2

Gene Symbol Gene ID Gene Info
CABZ01093502.2
ENSDARG00000105053 developing brain homeobox 2

Activity profile of CABZ01093502.2 motif

Sorted Z-values of CABZ01093502.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_26145013 0.54 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr6_-_58764672 0.35 ENSDART00000154322
soat2
sterol O-acyltransferase 2
chr12_-_10409961 0.31 ENSDART00000149521
ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr3_-_19368435 0.25 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr4_+_9669717 0.24 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr20_-_3915770 0.21 ENSDART00000159322
si:ch73-111k22.3
si:ch73-111k22.3
chr23_-_16485190 0.20 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr24_-_6078222 0.20 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr20_+_11731039 0.19 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr18_+_30847237 0.19 ENSDART00000012374
foxf1
forkhead box F1
chr8_-_50888806 0.18 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr21_+_28478663 0.18 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr4_-_9891874 0.17 ENSDART00000067193
adm2a
adrenomedullin 2a
chr15_-_21014270 0.17 ENSDART00000154019
si:ch211-212c13.10
si:ch211-212c13.10
chr25_-_6011034 0.17 ENSDART00000075197
ENSDART00000136054
snx22
sorting nexin 22
chr2_-_59327299 0.17 ENSDART00000133734
ftr36
finTRIM family, member 36
chr19_+_43780970 0.16 ENSDART00000063870
rpl11
ribosomal protein L11
chr8_+_6576940 0.16 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr24_-_38657683 0.15 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr11_-_1509773 0.15 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr21_-_20328375 0.14 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr14_-_413273 0.13 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr23_+_21405201 0.13 ENSDART00000144409
iffo2a
intermediate filament family orphan 2a
chr2_-_9818640 0.13 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr2_+_55984788 0.12 ENSDART00000183599
nmrk2
nicotinamide riboside kinase 2
chr24_-_7995960 0.12 ENSDART00000186594
bloc1s5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr6_+_13117598 0.12 ENSDART00000104744
casp8l1
caspase 8, apoptosis-related cysteine peptidase, like 1
chr10_-_20339113 0.12 ENSDART00000144378
ENSDART00000098600
zmat4b
zinc finger, matrin-type 4b
chr23_-_6522099 0.12 ENSDART00000092214
ENSDART00000183380
ENSDART00000138020
bmp7b
bone morphogenetic protein 7b
chr17_-_12764360 0.12 ENSDART00000003418
brms1la
breast cancer metastasis-suppressor 1-like a
chr12_-_28363111 0.11 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr16_+_54209504 0.11 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr17_+_49281597 0.11 ENSDART00000155599
zgc:113176
zgc:113176
chr14_-_34771371 0.10 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
ablim3
actin binding LIM protein family, member 3
chr5_+_34623107 0.10 ENSDART00000184126
enc1
ectodermal-neural cortex 1
chr6_+_7533601 0.09 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr22_-_26865361 0.09 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr9_-_42418470 0.09 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr8_-_30204650 0.08 ENSDART00000133209
zgc:162939
zgc:162939
chr13_-_12602920 0.08 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr22_-_24791505 0.08 ENSDART00000136837
vtg4
vitellogenin 4
chr22_-_36530902 0.07 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr11_-_29737088 0.07 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr3_+_25166805 0.07 ENSDART00000077493
TST
zgc:162544
chr2_+_2223837 0.07 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr1_-_31171242 0.06 ENSDART00000190294
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr7_-_17412559 0.05 ENSDART00000163020
nitr3a
novel immune-type receptor 3a
chr22_-_24818066 0.05 ENSDART00000143443
vtg6
vitellogenin 6
chr17_-_10122204 0.05 ENSDART00000160751
BX088587.1

chr2_+_20605925 0.05 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr2_+_19578446 0.05 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr2_+_19522082 0.05 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr22_-_14247276 0.04 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr2_+_14992879 0.04 ENSDART00000137546
pimr55
Pim proto-oncogene, serine/threonine kinase, related 55
chr15_-_46779934 0.04 ENSDART00000085136
clcn2c
chloride channel 2c
chr11_+_40812590 0.04 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr4_+_59845617 0.03 ENSDART00000167626
ENSDART00000123157
si:dkey-196n19.2
si:dkey-196n19.2
chr7_-_7692992 0.03 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr9_-_32177117 0.03 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr9_-_9415000 0.03 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr23_+_22656477 0.03 ENSDART00000009337
ENSDART00000133322
eno1a
enolase 1a, (alpha)
chr5_+_71802014 0.03 ENSDART00000124939
ENSDART00000097164
LHX3
LIM homeobox 3
chr24_-_33873451 0.03 ENSDART00000159840
asic1c
acid-sensing (proton-gated) ion channel 1c
chr15_-_17618800 0.02 ENSDART00000157185
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr22_-_26865181 0.02 ENSDART00000138311
hmox2a
heme oxygenase 2a
chr17_+_44780166 0.02 ENSDART00000156260
tmem63c
transmembrane protein 63C
chr21_-_38853737 0.02 ENSDART00000184100
tlr22
toll-like receptor 22
chr1_-_19502322 0.02 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr20_-_43663494 0.02 ENSDART00000144564
BX470188.1

chr25_+_3318192 0.02 ENSDART00000146154
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr1_+_51721851 0.01 ENSDART00000040397
prdx2
peroxiredoxin 2
chr9_-_51436377 0.01 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr19_+_46158078 0.01 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr3_-_59297532 0.01 ENSDART00000187991
CABZ01053748.1

chr24_+_28953089 0.01 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr3_+_45758760 0.01 ENSDART00000076007
gper1
G protein-coupled estrogen receptor 1
chr4_-_46915962 0.01 ENSDART00000169555
si:ch211-134c10.1
si:ch211-134c10.1
chr17_-_16422654 0.01 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr11_+_30057762 0.00 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01093502.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.0 0.4 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 0.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins