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PRJNA195909:zebrafish embryo and larva development

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Results for BX548005.1+smarcc2

Z-value: 5.62

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Transcription factors associated with BX548005.1+smarcc2

Gene Symbol Gene ID Gene Info
ENSDARG00000077946 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
ENSDARG00000110907 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smarcc2dr11_v1_chr6_+_39836474_39836474-0.481.9e-01Click!

Activity profile of BX548005.1+smarcc2 motif

Sorted Z-values of BX548005.1+smarcc2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_29537756 12.47 ENSDART00000103388
wu:fi42e03
chr5_-_43859148 10.31 ENSDART00000162746
ENSDART00000128763
si:ch211-204c21.1
chr17_-_16324565 10.29 ENSDART00000030835
homeobox containing 1a
chr25_+_9013342 9.34 ENSDART00000154207
ENSDART00000153705
im:7145024
chr11_-_16021424 9.26 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
chr24_-_5932982 9.26 ENSDART00000138412
ENSDART00000135124
ENSDART00000007373
acyl-CoA binding domain containing 5a
chr7_+_41887429 9.07 ENSDART00000115090
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr24_-_9989634 8.14 ENSDART00000115275
zgc:152652
chr3_-_31057624 7.94 ENSDART00000152901
armadillo repeat containing 5
chr24_+_21092156 7.87 ENSDART00000028542
coiled-coil domain containing 191
chr12_-_13730501 7.85 ENSDART00000152370
forkhead box H1
chr23_+_43668756 7.58 ENSDART00000112598
OTU deubiquitinase 4
chr14_+_30774515 7.33 ENSDART00000191666
atlastin 3
chr23_-_18415872 6.95 ENSDART00000135430
family with sequence similarity 120C
chr18_+_21951551 6.67 ENSDART00000146261
RAN binding protein 10
chr13_-_15929402 6.67 ENSDART00000090273
tubulin tyrosine ligase
chr20_-_3997531 6.63 ENSDART00000092217
tetratricopeptide repeat domain 13
chr14_+_41409697 6.54 ENSDART00000173335
BCL6 corepressor-like 1
chr2_-_57110477 6.39 ENSDART00000181132
solute carrier family 25, member 42
chr2_-_13254821 6.37 ENSDART00000022621
3-ketodihydrosphingosine reductase
chr23_+_13528550 6.27 ENSDART00000099903
uridine-cytidine kinase 1-like 1b
chr23_+_43870886 6.20 ENSDART00000102658
ENSDART00000149088
nuclear transcription factor, X-box binding-like 1
chr12_-_48467733 6.15 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
SEC31 homolog B, COPII coat complex component
chr2_+_42072231 5.88 ENSDART00000084517
valosin containing protein (p97)/p47 complex interacting protein 1
chr5_-_23675222 5.78 ENSDART00000135153
si:dkey-110k5.6
chr11_+_27134116 5.77 ENSDART00000129736
histone deacetylase 11
chr11_+_37638873 5.74 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
SH2 domain containing 5
chr14_+_30775066 5.74 ENSDART00000139975
ENSDART00000144921
atlastin 3
chr16_+_27442549 5.72 ENSDART00000015688
inversin
chr7_-_55292116 5.69 ENSDART00000122603
ring finger protein 166
chr11_+_27133560 5.54 ENSDART00000158411
histone deacetylase 11
chr1_+_24557414 5.52 ENSDART00000076519
dCTP pyrophosphatase 1
chr21_+_21791799 5.40 ENSDART00000151759
sialidase 3 (membrane sialidase), tandem duplicate 1
chr14_+_30774894 5.33 ENSDART00000023054
atlastin 3
chr20_-_31743553 5.27 ENSDART00000087405
SAM and SH3 domain containing 1a
chr5_+_3891485 5.24 ENSDART00000129329
ENSDART00000091711
RPA interacting protein
chr5_-_26795438 5.17 ENSDART00000146124
si:ch211-102c2.7
chr2_+_42072689 4.94 ENSDART00000134203
valosin containing protein (p97)/p47 complex interacting protein 1
chr15_+_2857556 4.93 ENSDART00000157758
MRE11 homolog A, double strand break repair nuclease
chr6_-_39700965 4.89 ENSDART00000156645
extra spindle pole bodies like 1, separase
chr16_-_41535690 4.80 ENSDART00000102662
ribonuclease P/MRP 25 subunit-like
chr11_-_18283886 4.80 ENSDART00000019248
STIM activating enhance
chr21_+_8427059 4.79 ENSDART00000143151
DENN/MADD domain containing 1A
chr21_+_21791343 4.77 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr4_+_25912654 4.73 ENSDART00000109508
ENSDART00000134218
vezatin, adherens junctions transmembrane protein
chr4_+_25912308 4.70 ENSDART00000167845
ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr24_+_29352039 4.65 ENSDART00000101641
protein arginine methyltransferase 6
chr23_+_33947874 4.63 ENSDART00000136104
si:ch211-148l7.4
chr19_-_12648122 4.63 ENSDART00000151184
family with sequence similarity 210, member Aa
chr6_-_58975010 4.57 ENSDART00000144911
ENSDART00000144514
methionyl-tRNA synthetase
chr16_-_34285106 4.53 ENSDART00000044235
phosphatase and actin regulator 4b
chr3_-_40664868 4.52 ENSDART00000138783
ENSDART00000178567
ring finger protein 216
chr13_-_24745288 4.44 ENSDART00000031564
SWI5-dependent homologous recombination repair protein 1
chr17_+_25187670 4.43 ENSDART00000190873
CLN8, transmembrane ER and ERGIC protein
chr11_+_35171406 4.43 ENSDART00000110839
MON1 secretory trafficking family member A
chr15_+_25528290 4.40 ENSDART00000123143
nuclear protein, ataxia-telangiectasia locus
chr15_-_37589600 4.35 ENSDART00000154641
proline and serine rich 3
chr18_-_16953978 4.33 ENSDART00000100126
A kinase (PRKA) interacting protein 1
chr25_-_8625601 4.32 ENSDART00000155280
zgc:153343
chr7_+_24523017 4.30 ENSDART00000077047
bloodthirsty-related gene family, member 9
chr8_+_40275830 4.28 ENSDART00000164414
ORAI calcium release-activated calcium modulator 1a
chr13_+_11073282 4.25 ENSDART00000114911
ENSDART00000182462
ENSDART00000148100
ENSDART00000137816
ENSDART00000134888
ENSDART00000131320
serologically defined colon cancer antigen 8
chr21_-_25613249 4.24 ENSDART00000137896
fibroblast growth factor (acidic) intracellular binding protein b
chr11_-_44999858 4.22 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr2_+_22659787 4.18 ENSDART00000043956
zgc:161973
chr3_+_62140077 4.14 ENSDART00000108945
GID complex subunit 4 homolog
chr23_-_26228077 4.12 ENSDART00000162423

chr15_-_31147301 4.11 ENSDART00000157145
ENSDART00000155473
ENSDART00000048103
kinase suppressor of ras 1b
chr20_-_31743817 4.11 ENSDART00000137679
SAM and SH3 domain containing 1a
chr2_+_5841108 4.09 ENSDART00000136180
DIS3 like 3'-5' exoribonuclease 2
chr16_+_38240027 4.03 ENSDART00000111081
prune exopolyphosphatase
chr23_-_26227805 4.02 ENSDART00000158082

chr12_+_48581588 3.99 ENSDART00000114996

chr21_+_26733529 3.92 ENSDART00000168379
pyruvate carboxylase a
chr2_-_13254594 3.87 ENSDART00000155671
3-ketodihydrosphingosine reductase
chr20_+_14789148 3.86 ENSDART00000164761
transmembrane p24 trafficking protein 5
chr5_+_8196264 3.85 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr16_+_23495600 3.83 ENSDART00000021092
sorting nexin family member 27b
chr21_+_170038 3.83 ENSDART00000157614
kelch-like family member 8
chr24_-_1657276 3.81 ENSDART00000168131
si:ch73-378g22.1
chr21_+_3854414 3.79 ENSDART00000122699
mitoguardin 2
chr5_-_67349916 3.79 ENSDART00000144092
MLX interacting protein
chr13_+_28785814 3.78 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr19_-_46058963 3.72 ENSDART00000170409
nucleoporin 153
chr14_-_493029 3.72 ENSDART00000115093
zgc:172215
chr11_-_33868881 3.71 ENSDART00000163295
ENSDART00000172633
ENSDART00000171439
si:ch211-227n13.3
chr1_-_53918839 3.69 ENSDART00000032552
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr4_+_6833735 3.66 ENSDART00000136355
dedicator of cytokinesis 4b
chr20_+_9474841 3.66 ENSDART00000053847
RAD51 paralog B
chr16_-_34401412 3.66 ENSDART00000054020
human immunodeficiency virus type I enhancer binding protein 3b
chr8_+_19624589 3.65 ENSDART00000185698
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr20_+_14789305 3.62 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr4_-_14954327 3.61 ENSDART00000182729
solute carrier family 26 (anion exchanger), member 5
chr3_+_35608385 3.61 ENSDART00000193219
ENSDART00000132703
TNF receptor-associated factor 7
chr13_-_48764180 3.61 ENSDART00000167157
si:ch1073-266p11.2
chr20_+_3997684 3.59 ENSDART00000113184
ARV1 homolog, fatty acid homeostasis modulator
chr3_+_15828999 3.58 ENSDART00000104397
transmembrane protein 11
chr10_+_36441124 3.52 ENSDART00000185626
ubiquitin specific peptidase like 1
chr3_+_27664864 3.51 ENSDART00000126533
ENSDART00000180848
chloride channel 7
chr25_-_31763897 3.51 ENSDART00000041740
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr16_-_2390931 3.50 ENSDART00000149463
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr20_+_5985329 3.49 ENSDART00000165489
centrosomal protein 128
chr4_-_5092335 3.48 ENSDART00000130453
adenosylhomocysteinase-like 2
chr18_+_2189211 3.47 ENSDART00000170827
cell cycle progression 1
chr8_+_52284075 3.42 ENSDART00000098439
ubiquitin-conjugating enzyme E2D 4 (putative)
chr3_-_26183699 3.41 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr19_+_2546775 3.39 ENSDART00000148527
ENSDART00000097528
sp4 transcription factor
chr14_-_32631519 3.38 ENSDART00000167282
ENSDART00000052938
ATPase phospholipid transporting 11C
chr19_+_40379771 3.37 ENSDART00000017917
ENSDART00000110699
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr11_+_37049105 3.36 ENSDART00000155408
bicaudal D homolog 2 (Drosophila)
chr3_+_27665160 3.35 ENSDART00000103660
chloride channel 7
chr7_-_26627252 3.33 ENSDART00000164050
ENSDART00000159826
PHD finger protein 23b
chr5_+_37379825 3.32 ENSDART00000171826
kelch-like family member 13
chr10_+_37182626 3.32 ENSDART00000137636
kinase suppressor of ras 1a
chr9_-_3519717 3.30 ENSDART00000145043
ddb1 and cul4 associated factor 17
chr21_+_19418563 3.28 ENSDART00000181113
ENSDART00000080110
alpha-methylacyl-CoA racemase
chr5_-_10082244 3.28 ENSDART00000036421
checkpoint kinase 2
chr16_-_30655980 3.27 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr18_-_46369516 3.20 ENSDART00000018163
interferon regulatory factor 2 binding protein 1
chr4_+_8670662 3.18 ENSDART00000168768
adiponectin receptor 2
chr10_+_44700103 3.16 ENSDART00000165999
scavenger receptor class B, member 1
chr13_+_39315881 3.16 ENSDART00000135999
si:dkey-85a20.4
chr21_-_11054605 3.16 ENSDART00000191378
ENSDART00000084061
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_26904774 3.16 ENSDART00000103690
C-type lectin domain containing 16A
chr19_-_12648408 3.16 ENSDART00000103692
family with sequence similarity 210, member Aa
chr8_-_16725959 3.15 ENSDART00000183593
DEP domain containing 1a
chr17_+_43659940 3.15 ENSDART00000145738
ENSDART00000075619
2-aminoethanethiol (cysteamine) dioxygenase b
chr25_+_15273370 3.11 ENSDART00000045659
t-complex 11, testis-specific-like 1
chr1_+_9153141 3.10 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr16_-_43971258 3.10 ENSDART00000141941
zinc finger protein, FOG family member 2a
chr13_+_42858228 3.06 ENSDART00000179763
cadherin-related 23
chr12_+_48390715 3.05 ENSDART00000149351
stearoyl-CoA desaturase (delta-9-desaturase)
chr25_-_20258508 3.04 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr8_+_25892319 3.03 ENSDART00000187167
ENSDART00000078163
transmembrane protein 115
chr9_+_37754845 3.02 ENSDART00000100592
protein disulfide isomerase family A, member 5
chr5_-_60885935 3.01 ENSDART00000128350
RAD51 paralog D
chr16_+_54674556 3.01 ENSDART00000167040
POP1 homolog, ribonuclease P/MRP subunit
chr1_-_59243542 3.01 ENSDART00000163021
multivesicular body subunit 12A
chr24_-_38131381 3.00 ENSDART00000105666
C-reactive protein 6
chr11_+_8152872 3.00 ENSDART00000091638
ENSDART00000138057
ENSDART00000166379
sterile alpha motif domain containing 13
chr13_-_33054847 2.99 ENSDART00000057379
ENSDART00000135955
vesicle transport through interaction with t-SNAREs 1B
chr1_+_32341734 2.99 ENSDART00000135078
pseudouridine 5'-phosphatase
chr17_-_24521382 2.97 ENSDART00000092948
pellino E3 ubiquitin protein ligase 1b
chr5_-_34921046 2.95 ENSDART00000180245
Rho guanine nucleotide exchange factor (GEF) 28
chr5_-_56948058 2.93 ENSDART00000083074
ENSDART00000191028
si:ch211-127d4.3
chr1_+_35494837 2.90 ENSDART00000140724
GRB2-associated binding protein 1
chr16_-_55259199 2.89 ENSDART00000161130
IQ motif containing GTPase activating protein 3
chr3_+_10637330 2.89 ENSDART00000129257
transmembrane protein 220
chr4_+_11483335 2.89 ENSDART00000184978
ENSDART00000140954
ankyrin repeat and SOCS box containing 13a, tandem duplicate 2
chr11_+_44503774 2.89 ENSDART00000169295
endoplasmic reticulum oxidoreductase beta
chr21_-_11054876 2.87 ENSDART00000146576
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_+_22867174 2.86 ENSDART00000035812
glutamate receptor, ionotropic, kainate 4
chr11_+_37049347 2.82 ENSDART00000109235
bicaudal D homolog 2 (Drosophila)
chr3_-_26184018 2.82 ENSDART00000191604
si:ch211-11k18.4
chr6_-_50730749 2.81 ENSDART00000157153
ENSDART00000110441
phosphatidylinositol glycan anchor biosynthesis, class U
chr6_-_16394528 2.80 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr16_-_39267185 2.79 ENSDART00000058550
ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1 like
chr4_-_14954029 2.78 ENSDART00000038642
solute carrier family 26 (anion exchanger), member 5
chr8_+_12951155 2.78 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr10_+_44699734 2.76 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scavenger receptor class B, member 1
chr19_+_41520892 2.74 ENSDART00000182218
ENSDART00000115123
CREB regulated transcription coactivator 2
chr22_+_22302614 2.71 ENSDART00000049434
secretory carrier membrane protein 4
chr8_-_11988065 2.71 ENSDART00000005140
mediator complex subunit 27
chr15_-_30450898 2.71 ENSDART00000156584
musashi RNA-binding protein 2b
chr15_-_25435085 2.69 ENSDART00000112079
TLC domain containing 2
chr19_+_9232676 2.69 ENSDART00000136957
lysine (K)-specific methyltransferase 2Ba
chr19_-_432083 2.68 ENSDART00000165371
dihydrouridine synthase 3-like (S. cerevisiae)
chr21_-_25801956 2.63 ENSDART00000101219
methyltransferase like 27
chr8_+_26396552 2.63 ENSDART00000087151
aminomethyltransferase
chr18_-_38245062 2.62 ENSDART00000189092
N-acetyltransferase 10
chr15_-_37543591 2.58 ENSDART00000180400
lysine (K)-specific methyltransferase 2Bb
chr9_+_38481780 2.56 ENSDART00000087241
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr8_+_23381892 2.56 ENSDART00000180950
ENSDART00000063010
ENSDART00000074241
ENSDART00000142783
microtubule-associated protein, RP/EB family, member 1a
chr6_+_58522738 2.56 ENSDART00000157327
ADP-ribosylation factor related protein 1
chr18_-_38244871 2.55 ENSDART00000076399
N-acetyltransferase 10
chr24_-_36301072 2.55 ENSDART00000062736
CoA synthase
chr13_-_26799244 2.55 ENSDART00000036419
vaccinia related kinase 2
chr8_-_31701157 2.53 ENSDART00000141799
F-box protein 4
chr22_-_506522 2.53 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr3_+_29179329 2.53 ENSDART00000085216
ENSDART00000190136
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr22_-_29689485 2.53 ENSDART00000182173
programmed cell death 4b
chr20_+_44498056 2.53 ENSDART00000023763
WD repeat and coiled coil containing
chr5_+_61361815 2.52 ENSDART00000009507
GATS protein-like 2
chr16_+_25107344 2.51 ENSDART00000033211
zgc:66448
chr7_+_33372680 2.50 ENSDART00000193436
ENSDART00000099988
glucuronic acid epimerase b
chr6_+_58522557 2.50 ENSDART00000128062
ADP-ribosylation factor related protein 1
chr19_-_23227582 2.47 ENSDART00000042172
growth factor receptor-bound protein 10a
chr6_+_8652310 2.46 ENSDART00000105098
ubiquitin specific peptidase 40
chr13_+_33655404 2.45 ENSDART00000023379
mitochondrial genome maintenance exonuclease 1
chr16_-_39195318 2.44 ENSDART00000058546
estrogen receptor binding site associated, antigen, 9
chr4_+_10604110 2.43 ENSDART00000122636
ENSDART00000037140
inhibitor of growth family, member 3
chr12_-_26620728 2.43 ENSDART00000087067
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr7_+_29863548 2.42 ENSDART00000136555
ENSDART00000134068
talin 2a
chr24_+_25032340 2.42 ENSDART00000005845
myotubularin related protein 6
chr21_-_41369539 2.40 ENSDART00000187546
cytoplasmic polyadenylation element binding protein 4b
chr19_+_26072624 2.39 ENSDART00000147627
jumonji, AT rich interactive domain 2b
chr13_+_2861265 2.38 ENSDART00000170602
ENSDART00000171687
si:ch211-233m11.2
chr20_-_2725594 2.37 ENSDART00000152120
akirin 2
chr2_-_22659450 2.37 ENSDART00000115025
THAP domain containing 4
chr15_-_23442891 2.35 ENSDART00000059376
ubiquitination factor E4A (UFD2 homolog, yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of BX548005.1+smarcc2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
2.6 7.9 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
2.6 10.2 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
2.0 5.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.9 7.6 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.8 5.5 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
1.6 6.4 GO:0019532 oxalate transport(GO:0019532)
1.5 9.3 GO:0030242 pexophagy(GO:0030242)
1.4 5.7 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
1.2 3.5 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
1.2 4.7 GO:0034969 histone arginine methylation(GO:0034969)
1.0 3.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.9 7.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.8 10.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.8 4.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.8 2.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.8 2.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.8 3.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.8 6.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.8 3.0 GO:0042148 strand invasion(GO:0042148)
0.7 2.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.7 5.8 GO:0044211 CTP salvage(GO:0044211)
0.7 3.5 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.7 2.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.7 2.8 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.7 5.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.7 4.8 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.7 2.7 GO:0055091 phospholipid homeostasis(GO:0055091)
0.7 2.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 4.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6 6.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.6 4.9 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.6 3.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.6 3.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.6 10.3 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.6 3.0 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.5 2.1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.5 3.6 GO:0032366 intracellular sterol transport(GO:0032366)
0.5 3.5 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 4.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.5 2.9 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.5 2.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.5 1.9 GO:0070199 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.5 3.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.5 24.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.4 1.7 GO:0002090 regulation of receptor internalization(GO:0002090)
0.4 2.1 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.4 2.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 2.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.4 4.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.4 1.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 0.8 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.4 4.0 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 3.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.3 1.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 2.7 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.3 3.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 3.6 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.3 2.3 GO:0030728 ovulation(GO:0030728)
0.3 4.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 2.9 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.3 3.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 0.9 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.3 5.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.3 6.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.3 2.6 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.3 9.3 GO:0007340 acrosome reaction(GO:0007340)
0.3 2.5 GO:0060036 notochord cell vacuolation(GO:0060036)
0.3 1.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 4.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 1.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 2.2 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.2 3.6 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 2.0 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 1.7 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 2.5 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 0.8 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.4 GO:0061511 centriole elongation(GO:0061511)
0.2 1.1 GO:0006574 valine catabolic process(GO:0006574)
0.2 2.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.2 2.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 2.5 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 1.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 2.7 GO:0046549 retinal cone cell development(GO:0046549)
0.2 2.7 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.2 2.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 5.2 GO:0000154 rRNA modification(GO:0000154)
0.2 7.0 GO:0032456 endocytic recycling(GO:0032456)
0.2 3.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 4.9 GO:0051307 meiotic chromosome separation(GO:0051307)
0.2 0.9 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.6 GO:0010039 response to iron ion(GO:0010039)
0.1 1.6 GO:0006903 vesicle targeting(GO:0006903)
0.1 0.9 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.3 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 9.9 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 4.7 GO:0009636 response to toxic substance(GO:0009636)
0.1 2.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.9 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 1.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 3.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 1.9 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 3.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.4 GO:0042407 cristae formation(GO:0042407)
0.1 1.0 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.6 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 2.2 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 4.1 GO:0006623 protein targeting to vacuole(GO:0006623)
0.1 7.5 GO:0007030 Golgi organization(GO:0007030)
0.1 0.4 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.1 3.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.6 GO:0007020 microtubule nucleation(GO:0007020)
0.1 1.0 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 1.3 GO:0035518 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.1 3.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 2.5 GO:0003171 atrioventricular valve development(GO:0003171)
0.1 2.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 2.3 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 3.1 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 2.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.1 8.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.1 4.5 GO:0021549 cerebellum development(GO:0021549)
0.1 0.9 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902)
0.1 4.4 GO:0055088 lipid homeostasis(GO:0055088)
0.1 1.3 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.1 0.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.3 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 0.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.5 GO:0039021 pronephric glomerulus development(GO:0039021)
0.1 3.8 GO:0006310 DNA recombination(GO:0006310)
0.1 6.9 GO:0006821 chloride transport(GO:0006821)
0.1 2.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 2.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 6.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 6.8 GO:0016197 endosomal transport(GO:0016197)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 2.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.0 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 2.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 2.9 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 2.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 1.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 2.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.8 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 7.1 GO:0060026 convergent extension(GO:0060026)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.2 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 2.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.7 GO:0008033 tRNA processing(GO:0008033)
0.0 0.7 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 10.5 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 9.9 GO:0016567 protein ubiquitination(GO:0016567)
0.0 1.3 GO:0090504 epiboly(GO:0090504)
0.0 1.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 1.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 4.1 GO:0008380 RNA splicing(GO:0008380)
0.0 0.5 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
1.1 3.4 GO:1990745 EARP complex(GO:1990745)
1.1 7.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.1 6.6 GO:0030870 Mre11 complex(GO:0030870)
0.8 1.6 GO:0032584 growth cone membrane(GO:0032584)
0.7 2.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.7 2.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.6 8.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.5 3.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.5 3.7 GO:0030914 STAGA complex(GO:0030914)
0.5 2.9 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 2.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 3.8 GO:0032021 NELF complex(GO:0032021)
0.4 1.9 GO:0018444 translation release factor complex(GO:0018444)
0.4 1.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.6 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.3 3.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 6.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 4.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 2.2 GO:0070552 BRISC complex(GO:0070552)
0.3 0.8 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.3 4.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.2 2.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 5.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 2.0 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 3.5 GO:0015030 Cajal body(GO:0015030)
0.2 3.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 0.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 3.0 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 1.6 GO:0071797 LUBAC complex(GO:0071797)
0.2 0.5 GO:0097541 axonemal basal plate(GO:0097541)
0.2 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 9.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 3.1 GO:0032420 stereocilium(GO:0032420)
0.1 2.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 5.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.2 GO:0016605 PML body(GO:0016605)
0.1 3.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 7.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 3.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.4 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 5.1 GO:0030496 midbody(GO:0030496)
0.1 1.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.9 GO:0005844 polysome(GO:0005844)
0.1 4.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 6.3 GO:0001726 ruffle(GO:0001726)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 1.2 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.3 GO:0042641 stress fiber(GO:0001725) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517)
0.1 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 4.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.3 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 12.7 GO:0000785 chromatin(GO:0000785)
0.0 2.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 3.4 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.5 GO:0005643 nuclear pore(GO:0005643)
0.0 3.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 4.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 10.0 GO:0005912 adherens junction(GO:0005912)
0.0 4.3 GO:0005769 early endosome(GO:0005769)
0.0 6.6 GO:0044441 ciliary part(GO:0044441)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.2 GO:0010008 endosome membrane(GO:0010008)
0.0 4.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.2 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.7 GO:0005795 Golgi stack(GO:0005795)
0.0 5.2 GO:0005730 nucleolus(GO:0005730)
0.0 11.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.6 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.6 4.7 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
1.3 3.9 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.2 5.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
1.1 12.0 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.9 4.7 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.9 10.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.9 5.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.8 6.7 GO:0034452 dynactin binding(GO:0034452)
0.8 4.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.8 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.8 3.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.8 6.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.7 3.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.7 2.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.7 5.8 GO:0004849 uridine kinase activity(GO:0004849)
0.7 2.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 3.5 GO:0032183 SUMO binding(GO:0032183)
0.7 2.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.7 7.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.7 3.3 GO:0070412 R-SMAD binding(GO:0070412)
0.6 1.9 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.6 2.5 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.6 4.2 GO:0030274 LIM domain binding(GO:0030274)
0.6 2.8 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5 2.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.5 4.4 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.5 7.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 2.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 1.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.4 3.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.4 2.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 2.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 6.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 1.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 4.0 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 3.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 1.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 2.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 9.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 5.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.5 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.3 4.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 6.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 2.6 GO:0008483 transaminase activity(GO:0008483)
0.3 1.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.3 2.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 2.0 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 2.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 4.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 2.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 1.6 GO:0070888 E-box binding(GO:0070888)
0.2 2.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.9 GO:0016671 protein disulfide isomerase activity(GO:0003756) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 1.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 0.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 9.4 GO:0017022 myosin binding(GO:0017022)
0.2 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 1.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 4.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 4.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 4.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 3.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 1.2 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 1.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 4.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 3.5 GO:0031267 small GTPase binding(GO:0031267)
0.2 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 2.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 9.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.4 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.1 5.2 GO:0000049 tRNA binding(GO:0000049)
0.1 7.9 GO:0046332 SMAD binding(GO:0046332)
0.1 2.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 2.1 GO:0008301 DNA binding, bending(GO:0008301)
0.1 14.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.6 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 3.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.8 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 7.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 2.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 7.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 4.4 GO:0045296 cadherin binding(GO:0045296)
0.0 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 7.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 1.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 5.9 GO:0016874 ligase activity(GO:0016874)
0.0 2.7 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 2.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 14.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 13.1 GO:0005525 GTP binding(GO:0005525)
0.0 3.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0016853 isomerase activity(GO:0016853)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 4.8 GO:0003682 chromatin binding(GO:0003682)
0.0 1.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 2.3 GO:0016791 phosphatase activity(GO:0016791)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 9.9 PID ATM PATHWAY ATM pathway
0.2 3.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 7.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 8.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 8.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.3 PID AURORA B PATHWAY Aurora B signaling
0.1 1.6 PID INSULIN PATHWAY Insulin Pathway
0.1 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.8 7.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.7 3.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 5.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 10.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 3.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 6.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 3.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 11.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 2.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 2.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 4.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 2.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 6.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 5.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 3.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 5.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation