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PRJNA195909:zebrafish embryo and larva development
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Results for BX548005.1+smarcc2
Z-value: 5.62
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Transcription factors associated with BX548005.1+smarcc2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSDARG00000077946 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | |
| ENSDARG00000110907 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| smarcc2 | dr11_v1_chr6_+_39836474_39836474 | -0.48 | 1.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_29537756 Show fit | 12.47 |
ENSDART00000103388
|
wu:fi42e03 |
|
| chr5_-_43859148 Show fit | 10.31 |
ENSDART00000162746
ENSDART00000128763 |
si:ch211-204c21.1 |
|
| chr17_-_16324565 Show fit | 10.29 |
ENSDART00000030835
|
homeobox containing 1a |
|
| chr25_+_9013342 Show fit | 9.34 |
ENSDART00000154207
ENSDART00000153705 |
im:7145024 |
|
| chr11_-_16021424 Show fit | 9.26 |
ENSDART00000193291
ENSDART00000170731 ENSDART00000104107 |
zgc:173544 |
|
| chr24_-_5932982 Show fit | 9.26 |
ENSDART00000138412
ENSDART00000135124 ENSDART00000007373 |
acyl-CoA binding domain containing 5a |
|
| chr7_+_41887429 Show fit | 9.07 |
ENSDART00000115090
|
glutamic pyruvate transaminase (alanine aminotransferase) 2 |
|
| chr24_-_9989634 Show fit | 8.14 |
ENSDART00000115275
|
zgc:152652 |
|
| chr3_-_31057624 Show fit | 7.94 |
ENSDART00000152901
|
armadillo repeat containing 5 |
|
| chr24_+_21092156 Show fit | 7.87 |
ENSDART00000028542
|
coiled-coil domain containing 191 |
Network of associatons between targets according to the STRING database.
First level regulatory network of BX548005.1+smarcc2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 24.5 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 2.9 | 11.5 | GO:0048308 | organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313) |
| 0.0 | 10.5 | GO:0007264 | small GTPase mediated signal transduction(GO:0007264) |
| 0.6 | 10.3 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 2.6 | 10.2 | GO:0030220 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
| 0.8 | 10.2 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 0.1 | 9.9 | GO:1902593 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593) |
| 0.0 | 9.9 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 1.5 | 9.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.3 | 9.3 | GO:0007340 | acrosome reaction(GO:0007340) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.7 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 11.6 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 1.4 | 11.1 | GO:0033061 | DNA recombinase mediator complex(GO:0033061) |
| 0.0 | 10.0 | GO:0005912 | adherens junction(GO:0005912) |
| 0.2 | 9.8 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.6 | 8.4 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 1.1 | 7.8 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.1 | 7.1 | GO:0072686 | mitotic spindle(GO:0072686) |
| 1.1 | 6.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 6.6 | GO:0044441 | ciliary part(GO:0044441) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 14.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 13.1 | GO:0005525 | GTP binding(GO:0005525) |
| 1.1 | 12.0 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.9 | 10.2 | GO:0052795 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.2 | 9.4 | GO:0017022 | myosin binding(GO:0017022) |
| 0.3 | 9.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 9.1 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.1 | 7.9 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.5 | 7.6 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 11.3 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.3 | 9.9 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 8.9 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 8.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 7.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.2 | 3.7 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 3.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 2.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 2.7 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 2.3 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 11.3 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.4 | 10.2 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.9 | 9.1 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.8 | 7.9 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.3 | 6.6 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 6.3 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.5 | 5.9 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 5.6 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 5.4 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 4.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |