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PRJEB1986: zebrafish developmental stages transcriptome

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Results for znf740b

Z-value: 0.93

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Transcription factors associated with znf740b

Gene Symbol Gene ID Gene Info
ENSDARG00000061174 zinc finger protein 740b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf740bdr11_v1_chr23_-_36418708_36418708-0.734.3e-04Click!

Activity profile of znf740b motif

Sorted Z-values of znf740b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_6954984 8.90 ENSDART00000145610
si:ch211-255g12.6
chr25_-_18470695 3.76 ENSDART00000034377
carboxypeptidase A5
chr21_+_25660613 3.32 ENSDART00000134017
si:dkey-17e16.15
chr6_+_38381957 2.80 ENSDART00000087300
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_+_13244149 2.78 ENSDART00000186984
ENSDART00000105896
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr16_-_8280885 2.36 ENSDART00000129068
ectonucleoside triphosphate diphosphohydrolase 3
chr12_-_4540564 2.32 ENSDART00000106566

chr3_-_1190132 2.24 ENSDART00000149709
single-pass membrane protein with aspartate-rich tail 1a
chr9_+_13714379 2.18 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr11_-_24191928 2.15 ENSDART00000136827
SRY (sex determining region Y)-box 12
chr3_+_22327738 2.09 ENSDART00000055675
growth hormone 1
chr2_+_7192966 1.98 ENSDART00000142735
si:ch211-13f8.1
chr25_+_37366698 1.97 ENSDART00000165400
ENSDART00000192589
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr17_-_12389259 1.85 ENSDART00000185724
synaptosomal-associated protein, 25b
chr3_-_52614747 1.83 ENSDART00000154365
tripartite motif containing 35-13
chr23_+_6232895 1.80 ENSDART00000139795
synaptotagmin IIa
chr25_+_13191391 1.80 ENSDART00000109937
si:ch211-147m6.2
chr21_+_1143141 1.75 ENSDART00000178294

chr14_+_22172047 1.67 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr3_-_61162750 1.66 ENSDART00000055064
parvalbumin 8
chr3_+_50312422 1.65 ENSDART00000157689
growth arrest-specific 7a
chr11_-_97817 1.65 ENSDART00000092903
engulfment and cell motility 2
chr20_-_25542183 1.60 ENSDART00000024350
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr15_-_28618502 1.54 ENSDART00000086902
solute carrier family 6 (neurotransmitter transporter), member 4a
chr7_-_27686021 1.53 ENSDART00000079112
ENSDART00000100989
calcitonin/calcitonin-related polypeptide, alpha
chr8_-_22739757 1.49 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr19_+_48117995 1.42 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr21_-_37889727 1.39 ENSDART00000163612
ENSDART00000180958
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr19_-_6873107 1.35 ENSDART00000124440

chr24_-_32582378 1.34 ENSDART00000066590
retinol dehydrogenase 12, like
chr9_+_54290896 1.32 ENSDART00000149175
POU class 4 homeobox 3
chr22_+_35068046 1.31 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
chr15_-_5815006 1.31 ENSDART00000102459
retinol binding protein 2a, cellular
chr5_+_32162684 1.29 ENSDART00000134472
TAO kinase 3b
chr10_-_43540196 1.21 ENSDART00000170891
si:ch73-215f7.1
chr16_-_27749172 1.18 ENSDART00000145198
STEAP family member 4
chr20_-_25518488 1.17 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr20_+_20672163 1.17 ENSDART00000027758
reticulon 1b
chr22_+_24157807 1.16 ENSDART00000159165
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_+_5530247 1.15 ENSDART00000114637
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr1_+_31112436 1.15 ENSDART00000075340
eukaryotic translation elongation factor 1 alpha 1b
chr25_+_13191615 1.08 ENSDART00000168849
si:ch211-147m6.2
chr13_+_28702104 1.06 ENSDART00000135481
si:ch211-67n3.9
chr10_-_35542071 1.02 ENSDART00000162139
si:ch211-244c8.4
chr3_+_13440900 0.99 ENSDART00000143715
si:dkey-117i10.1
chr11_+_38280454 0.97 ENSDART00000171496
si:dkey-166c18.1
chr5_-_68022631 0.96 ENSDART00000143199
WAS protein family, member 3a
chr1_+_51896147 0.95 ENSDART00000167139
nuclear factor I/Xa
chr18_-_16181952 0.93 ENSDART00000157824
solute carrier family 6 (neutral amino acid transporter), member 15
chr14_+_33458294 0.93 ENSDART00000075278
ATPase Na+/K+ transporting subunit beta 4
chr19_+_13994563 0.92 ENSDART00000164696
transmembrane protein 222b
chr19_-_7358184 0.92 ENSDART00000092379
oxidation resistance 1b
chr18_+_21122818 0.91 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr5_+_9382301 0.90 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr5_+_30699260 0.89 ENSDART00000012888
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr18_+_45990394 0.88 ENSDART00000024068
matrix metallopeptidase 23bb
chr24_-_28243186 0.87 ENSDART00000105691
cytochrome c oxidase subunit IV isoform 1, like
chr8_-_37328112 0.86 ENSDART00000140365
solute carrier family 12 (potassium/chloride transporter), member 5b
chr10_-_22249444 0.85 ENSDART00000148831
fibroblast growth factor 11b
chr1_-_38709551 0.85 ENSDART00000128794
glycoprotein M6Ab
chr12_+_24561832 0.85 ENSDART00000088159
neurexin 1a
chr24_-_38110779 0.84 ENSDART00000147783
c-reactive protein, pentraxin-related
chr23_-_35064785 0.84 ENSDART00000172240

chr7_+_23495986 0.83 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr15_-_12229874 0.83 ENSDART00000165159
Down syndrome cell adhesion molecule like 1
chr2_-_36818132 0.82 ENSDART00000110447
SLIT and NTRK-like family, member 3b
chr25_-_37501371 0.82 ENSDART00000160498

chr16_+_1803462 0.82 ENSDART00000183974
glutamate ionotropic receptor kainate type subunit 2
chr9_-_18877597 0.82 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr13_+_23677949 0.82 ENSDART00000144215
pecanex-like 2 (Drosophila)
chr7_-_19043401 0.81 ENSDART00000158796
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr16_+_10918252 0.80 ENSDART00000172949
POU class 2 homeobox 2a
chr3_-_33417826 0.80 ENSDART00000084284
ABI family, member 3a
chr25_+_4750972 0.79 ENSDART00000168903
si:zfos-2372e4.1
chr5_+_36614196 0.77 ENSDART00000150574
neuro-oncological ventral antigen 1
chr15_-_30832897 0.77 ENSDART00000152330
musashi RNA-binding protein 2b
chr20_-_51727860 0.75 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr24_-_21674950 0.75 ENSDART00000123216
ENSDART00000046211
ligand of numb-protein X 2a
chr5_-_19052184 0.74 ENSDART00000133330
family with sequence similarity 214, member B
chr2_+_51783120 0.74 ENSDART00000177559
crystallin, gamma N1
chr7_-_57949117 0.73 ENSDART00000138803
ankyrin 2b, neuronal
chr2_+_28889936 0.73 ENSDART00000078232
cadherin 10, type 2a (T2-cadherin)
chr24_-_28381404 0.73 ENSDART00000148406
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr11_+_6650966 0.72 ENSDART00000131236
si:dkey-246j7.1
chr12_+_2522642 0.72 ENSDART00000152567
FERM and PDZ domain containing 2
chr23_+_42434348 0.72 ENSDART00000161027
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr21_+_11244068 0.71 ENSDART00000163432
AT-rich interaction domain 6
chr24_+_15020402 0.69 ENSDART00000148102
docking protein 6
chr25_+_25464630 0.68 ENSDART00000150537
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr5_+_6892195 0.68 ENSDART00000048201
expressed sequence CR929477
chr2_-_23004286 0.65 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr2_+_22694382 0.65 ENSDART00000139196
kinesin family member 1Ab
chr13_-_29505604 0.65 ENSDART00000110005
cadherin-related family member 1a
chr1_-_46632948 0.64 ENSDART00000148893
ENSDART00000053232
cytidine and dCMP deaminase domain containing 1
chr9_-_704667 0.64 ENSDART00000147092
CASP8 and FADD-like apoptosis regulator b
chr24_+_41931585 0.64 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr12_-_22540943 0.64 ENSDART00000172310
zinc finger and BTB domain containing 4
chr21_+_5635420 0.64 ENSDART00000168158
shroom family member 3
chr6_+_58492201 0.63 ENSDART00000156375
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr14_-_2369849 0.62 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
protocadherin b
chr2_+_3595333 0.61 ENSDART00000041052
complement component 1, q subcomponent-like 3b
chr9_-_54001502 0.61 ENSDART00000085253
midline 1
chr23_-_41651759 0.61 ENSDART00000146808
si:ch73-184c24.1
chr2_+_58221163 0.60 ENSDART00000157939

chr21_+_7823146 0.60 ENSDART00000030579
corticotropin releasing hormone binding protein
chr16_-_17586883 0.60 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr8_+_36803415 0.59 ENSDART00000111680
IQ motif and Sec7 domain 2b
chr18_+_41232719 0.59 ENSDART00000138552
ENSDART00000145863
thyroid hormone receptor interactor 12
chr9_+_7358749 0.59 ENSDART00000081660
Indian hedgehog homolog a
chr15_-_10455438 0.59 ENSDART00000158958
ENSDART00000192971
ENSDART00000162133
ENSDART00000185071
ENSDART00000192444
ENSDART00000165668
ENSDART00000175825
teneurin transmembrane protein 4
chr9_-_43073960 0.58 ENSDART00000059460
titin, tandem duplicate 2
chr1_-_42779075 0.58 ENSDART00000133917
leucine rich repeat transmembrane neuronal 1
chr5_-_70625697 0.58 ENSDART00000179538
ENSDART00000190540

chr16_+_9713850 0.58 ENSDART00000164103
extracellular matrix protein 1b
chr12_+_35203091 0.57 ENSDART00000153022
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr5_-_41841675 0.57 ENSDART00000141683
si:dkey-65b12.6
chr25_+_3788074 0.57 ENSDART00000154008
chitinase domain containing 1
chr21_-_22485847 0.56 ENSDART00000162860
myosin VB
chr22_+_28446365 0.56 ENSDART00000189359
ABI family, member 3 (NESH) binding protein b
chr16_-_41439659 0.55 ENSDART00000191624
copine IVa
chr23_-_17470146 0.55 ENSDART00000002398
tripartite motif containing 101
chr7_-_35126374 0.55 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr9_+_5862040 0.54 ENSDART00000129117
PDZ domain containing 1
chr2_-_4496358 0.53 ENSDART00000158216
adiponectin, C1Q and collagen domain containing, b
chr25_+_3788443 0.53 ENSDART00000189747
chitinase domain containing 1
chr5_-_71838520 0.53 ENSDART00000174396

chr18_-_7810214 0.53 ENSDART00000139505
ENSDART00000139188
SH3 and multiple ankyrin repeat domains 3a
chr19_-_10043142 0.52 ENSDART00000193016
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
chr21_-_10488379 0.52 ENSDART00000163878
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr18_-_19350792 0.52 ENSDART00000147902
multiple EGF-like-domains 11
chr11_-_41130239 0.51 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr3_-_59981162 0.50 ENSDART00000128790
cerebellar degeneration-related protein 2-like
chr15_+_3284416 0.49 ENSDART00000187665
ENSDART00000171723
forkhead box O1 a
chr8_-_23578660 0.49 ENSDART00000039080
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr13_-_29505946 0.49 ENSDART00000026679
cadherin-related family member 1a
chr12_+_42436328 0.49 ENSDART00000167324
early B cell factor 3a
chr8_-_5847533 0.48 ENSDART00000192489

chr8_+_26268100 0.48 ENSDART00000138882
solute carrier family 26, member 6
chr20_-_37629084 0.48 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr11_+_12052791 0.47 ENSDART00000158479
si:ch211-156l18.8
chr21_-_15046065 0.47 ENSDART00000178507
matrix metallopeptidase 17a
chr13_-_27767330 0.47 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr16_+_47428721 0.47 ENSDART00000180597
ENSDART00000032309
solute carrier family 25 (mitochondrial folate carrier), member 32b
chr8_+_46010838 0.47 ENSDART00000143126
si:ch211-119d14.2
chr20_+_50184934 0.47 ENSDART00000158388
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr10_+_24445698 0.46 ENSDART00000146370
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_-_42778510 0.46 ENSDART00000190172
leucine rich repeat transmembrane neuronal 1
chr20_-_25669813 0.46 ENSDART00000153118
si:dkeyp-117h8.2
chr8_+_28900689 0.46 ENSDART00000141634
glutamate receptor, ionotropic, delta 2
chr19_-_25519310 0.46 ENSDART00000089882
si:dkey-202e17.1
chr15_+_42767803 0.45 ENSDART00000164879
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr20_-_42100932 0.45 ENSDART00000191930
solute carrier family 35, member F1
chr11_-_9808356 0.45 ENSDART00000167465
neuroligin 1
chr16_+_10963602 0.45 ENSDART00000141032
POU class 2 homeobox 2a
chr22_+_28446557 0.45 ENSDART00000089546
ABI family, member 3 (NESH) binding protein b
chr10_-_25543227 0.44 ENSDART00000007778
glutamate receptor, ionotropic, kainate 1a
chr9_+_29585943 0.44 ENSDART00000185989
ENSDART00000115290
mcf.2 cell line derived transforming sequence-like b
chr18_-_42333428 0.44 ENSDART00000034225
contactin 5
chr3_-_59981476 0.44 ENSDART00000035878
ENSDART00000124038
cerebellar degeneration-related protein 2-like
chr17_-_8976307 0.44 ENSDART00000092113
zinc finger, RAN-binding domain containing 1b
chr17_+_5846202 0.42 ENSDART00000189713
fibronectin type III domain containing 4b
chr12_-_47899497 0.42 ENSDART00000162219
pyroglutamylated RFamide peptide receptor
chr5_-_30074332 0.42 ENSDART00000147963
beta-carotene oxygenase 2a
chr6_-_13498745 0.41 ENSDART00000027684
ENSDART00000189438
myosin light chain kinase b
chr23_-_524780 0.41 ENSDART00000055139
collagen, type IX, alpha 3
chr17_-_22062364 0.40 ENSDART00000114470
tau tubulin kinase 1b
chr12_+_35070085 0.40 ENSDART00000190603
synaptotagmin XV
chr19_-_25519612 0.40 ENSDART00000133150
si:dkey-202e17.1
chr17_-_2811992 0.39 ENSDART00000067543
G protein-coupled receptor 65
chr6_-_43677125 0.38 ENSDART00000150128
forkhead box P1b
chr10_-_24961310 0.38 ENSDART00000037303
si:ch211-214k5.3
chr11_-_4235811 0.37 ENSDART00000121716
si:ch211-236d3.4
chr8_-_20230559 0.37 ENSDART00000193677
MLLT1, super elongation complex subunit a
chr5_-_30080332 0.37 ENSDART00000140049
beta-carotene oxygenase 2a
chr12_+_36092218 0.37 ENSDART00000168694
BTB (POZ) domain containing 17a
chr4_+_74554605 0.37 ENSDART00000009653
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr12_-_7854216 0.37 ENSDART00000149594
ankyrin 3b
chr16_+_32152612 0.36 ENSDART00000008880
G protein-coupled receptor, class C, group 6, member A
chr5_-_24642026 0.36 ENSDART00000139522
si:ch211-106a19.1
chr25_-_11088839 0.36 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr20_-_20610812 0.36 ENSDART00000181870
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr18_-_46882649 0.35 ENSDART00000192056
GRAM domain containing 1Bb
chr13_-_8776474 0.35 ENSDART00000122371
si:ch211-93n23.7
chr8_-_31393429 0.34 ENSDART00000192369
NIM1 serine/threonine protein kinase
chr21_-_11820379 0.34 ENSDART00000126640
si:dkey-6b12.5
chr4_+_3980247 0.34 ENSDART00000049194
G protein-coupled receptor 37b
chr3_+_52467879 0.34 ENSDART00000156039
adhesion G protein-coupled receptor E5a
chr20_-_42102416 0.34 ENSDART00000186378
ENSDART00000188253
ENSDART00000186458
solute carrier family 35, member F1
chr10_-_39283883 0.34 ENSDART00000023831
cryptochrome circadian clock 5
chr11_-_7078392 0.33 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
chr25_-_19395476 0.33 ENSDART00000182622
microtubule-associated protein 1Ab
chr1_+_7414318 0.33 ENSDART00000127426
si:ch73-383l1.1
chr7_-_72426484 0.33 ENSDART00000190063
rabphilin 3A homolog (mouse), b
chr2_-_44183451 0.32 ENSDART00000111246
cell adhesion molecule 3
chr9_+_8942258 0.32 ENSDART00000138836
ankyrin repeat domain 10b
chr6_+_54239625 0.32 ENSDART00000149542
protein kinase C and casein kinase substrate in neurons 1b
chr19_+_32257472 0.32 ENSDART00000186471
ataxin 1a
chr3_+_36972586 0.31 ENSDART00000102784
si:ch211-18i17.2
chr17_+_3379673 0.31 ENSDART00000176354
syntrophin, gamma 2
chr10_+_42159471 0.30 ENSDART00000122160

Network of associatons between targets according to the STRING database.

First level regulatory network of znf740b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.4 1.5 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.3 1.2 GO:0015677 copper ion import(GO:0015677)
0.2 0.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.6 GO:0060031 mediolateral intercalation(GO:0060031)
0.2 0.6 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.2 2.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 2.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.7 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 2.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.4 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.8 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.6 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 2.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 4.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.0 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 3.2 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.4 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 1.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 2.0 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0001843 neural tube closure(GO:0001843)
0.0 0.3 GO:0042493 response to drug(GO:0042493)
0.0 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.4 GO:1903707 negative regulation of hemopoiesis(GO:1903707)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 4.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.6 GO:0006909 phagocytosis(GO:0006909)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.9 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 1.4 GO:0060027 convergent extension involved in gastrulation(GO:0060027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 0.8 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.2 2.2 GO:1990246 uniplex complex(GO:1990246)
0.1 4.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.6 GO:0043194 axon initial segment(GO:0043194)
0.1 0.9 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.2 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.8 GO:0045177 apical part of cell(GO:0045177)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.5 1.5 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.5 1.5 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 1.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.2 1.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 2.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 4.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.3 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 2.0 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.8 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.1 GO:0008061 chitin binding(GO:0008061)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.2 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 3.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 1.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 1.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0016208 AMP binding(GO:0016208)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.0 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions