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PRJEB1986: zebrafish developmental stages transcriptome

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Results for zic2a+zic2b

Z-value: 0.90

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Transcription factors associated with zic2a+zic2b

Gene Symbol Gene ID Gene Info
ENSDARG00000015554 zic family member 2 (odd-paired homolog, Drosophila), a
ENSDARG00000037178 zic family member 2 (odd-paired homolog, Drosophila) b
ENSDARG00000112354 zic family member 2 (odd-paired homolog, Drosophila) b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zic2adr11_v1_chr9_+_31282161_31282161-0.341.6e-01Click!
zic2bdr11_v1_chr1_+_29858032_29858032-0.302.1e-01Click!

Activity profile of zic2a+zic2b motif

Sorted Z-values of zic2a+zic2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_83873 6.57 ENSDART00000162145
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr20_-_25518488 2.95 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr4_-_55785014 2.87 ENSDART00000181348

chr4_-_55801210 2.87 ENSDART00000186943

chr4_-_55829342 2.81 ENSDART00000185611

chr18_-_40684756 2.10 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
chr19_-_10196370 2.09 ENSDART00000091707
D site albumin promoter binding protein a
chr5_+_13521081 1.97 ENSDART00000171975
si:ch211-230g14.6
chr12_+_47162761 1.95 ENSDART00000192339
ENSDART00000167726
ryanodine receptor 2
chr14_-_49859747 1.94 ENSDART00000169456
ENSDART00000164967
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr13_+_3252950 1.90 ENSDART00000020671
peripherin 2b (retinal degeneration, slow)
chr11_-_4235811 1.89 ENSDART00000121716
si:ch211-236d3.4
chr19_+_9050852 1.84 ENSDART00000151031
ash1 (absent, small, or homeotic)-like (Drosophila)
chr12_+_47162456 1.54 ENSDART00000186272
ENSDART00000180811
ryanodine receptor 2
chr15_-_12229874 1.53 ENSDART00000165159
Down syndrome cell adhesion molecule like 1
chr2_+_51783120 1.33 ENSDART00000177559
crystallin, gamma N1
chr2_-_57707039 1.32 ENSDART00000097685

chr20_-_915234 1.29 ENSDART00000164816
cannabinoid receptor 1
chr10_+_2876020 1.28 ENSDART00000136618
ENSDART00000133128
ENSDART00000140803
ENSDART00000141505
cell cycle and apoptosis regulator 2
chr9_+_54417141 1.26 ENSDART00000056810
dopamine receptor D1b
chr21_-_42055872 1.25 ENSDART00000144767
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr15_-_26844591 1.21 ENSDART00000077582
PITPNM family member 3
chr24_-_26622423 1.19 ENSDART00000182044
TRAF2 and NCK interacting kinase b
chr12_-_6905375 1.18 ENSDART00000152322
protocadherin-related 15b
chr4_-_75175407 1.16 ENSDART00000180125

chr17_-_34952562 1.08 ENSDART00000021128
kinase D-interacting substrate 220a
chr9_+_6082793 1.06 ENSDART00000192045
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr20_-_36671660 1.06 ENSDART00000134819
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr20_-_7000225 1.05 ENSDART00000100098
adenylate cyclase 1a
chr19_-_6982272 0.99 ENSDART00000141913
ENSDART00000150957
zinc finger protein 384 like
chr15_-_24178893 0.97 ENSDART00000077980
pipecolic acid oxidase
chr20_+_1996202 0.96 ENSDART00000184143

chr22_-_38459316 0.96 ENSDART00000149683
ENSDART00000098461
protein tyrosine kinase 7a
chr5_-_30151815 0.95 ENSDART00000156048
zinc finger and BTB domain containing 44
chr4_-_2219705 0.95 ENSDART00000131046
si:ch73-278m9.1
chr1_-_18446161 0.94 ENSDART00000089442
kelch-like family member 5
chr16_-_2558653 0.93 ENSDART00000110365
adenylate cyclase 3a
chr18_+_9641210 0.92 ENSDART00000182024
piccolo presynaptic cytomatrix protein b
chr3_-_62380146 0.91 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr10_+_40235959 0.88 ENSDART00000145862
GRAM domain containing 1Ba
chr19_-_22568203 0.87 ENSDART00000182888
plectin a
chr23_+_2542158 0.83 ENSDART00000182197

chr24_+_3972260 0.78 ENSDART00000131753
phosphofructokinase, platelet a
chr3_-_3209432 0.78 ENSDART00000140635
si:ch211-229i14.2
chr11_-_19097746 0.76 ENSDART00000103973
rhodopsin, like
chr11_+_41560792 0.76 ENSDART00000127292
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr1_-_23370395 0.75 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr1_-_58880613 0.74 ENSDART00000188136

chr4_+_10365857 0.74 ENSDART00000138890
potassium voltage-gated channel, Shal-related subfamily, member 2
chr16_+_48729947 0.74 ENSDART00000049051
bromodomain containing 2b
chr24_-_21490628 0.72 ENSDART00000181546
ATPase phospholipid transporting 8A2
chr14_+_25464681 0.70 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr21_+_17110598 0.70 ENSDART00000101282
ENSDART00000191864
breakpoint cluster region
chr21_-_45588720 0.70 ENSDART00000186642
ENSDART00000189531

chr10_+_35329751 0.69 ENSDART00000148043
si:dkey-259j3.5
chr15_+_31276869 0.69 ENSDART00000156355
si:ch211-244e12.7
chr18_+_9637744 0.68 ENSDART00000190171
piccolo presynaptic cytomatrix protein b
chr1_-_45042210 0.67 ENSDART00000073694
SMU1, DNA replication regulator and spliceosomal factor b
chr2_-_33993533 0.66 ENSDART00000140910
ENSDART00000077304
patched 2
chr11_+_25459697 0.65 ENSDART00000161481
opsin 1 (cone pigments), short-wave-sensitive 2
chr3_-_37351225 0.65 ENSDART00000174685
si:ch211-278a6.1
chr4_+_4902392 0.65 ENSDART00000133866
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr7_-_55292116 0.65 ENSDART00000122603
ring finger protein 166
chr19_-_46566430 0.63 ENSDART00000166668
exostosin glycosyltransferase 1b
chr22_+_9806867 0.63 ENSDART00000137182
ENSDART00000106103
si:ch211-236g6.1
chr21_-_26520629 0.63 ENSDART00000142731
Ras converting CAAX endopeptidase 1b
chr1_+_39597809 0.58 ENSDART00000122700
teneurin transmembrane protein 3
chr3_-_55537096 0.57 ENSDART00000123544
ENSDART00000188752
testis expressed 2
chr12_-_124264 0.57 ENSDART00000181551

chr20_+_26095530 0.56 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr3_-_40068350 0.56 ENSDART00000185292
myosin XVAa
chr22_-_7809904 0.56 ENSDART00000182269
ENSDART00000097201
ENSDART00000138522
si:ch73-44m9.3
si:ch73-44m9.1
chr8_-_49304602 0.55 ENSDART00000147020
prickle homolog 3
chr17_-_7371564 0.54 ENSDART00000060336
RAB32b, member RAS oncogene family
chr17_+_20605013 0.52 ENSDART00000156878
si:ch73-288o11.5
chr9_+_24159725 0.52 ENSDART00000137756
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr8_+_29962635 0.52 ENSDART00000007640
patched 1
chr4_-_46948863 0.51 ENSDART00000168835
si:dkey-16p6.1
chr3_-_30118856 0.51 ENSDART00000109953
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr21_-_44731865 0.51 ENSDART00000013814
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr5_+_36439405 0.50 ENSDART00000102973
ectodysplasin A
chr17_-_8562586 0.49 ENSDART00000154257
ENSDART00000157308
frizzled class receptor 3b
chr18_-_1143996 0.48 ENSDART00000189186
ENSDART00000136140
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr17_+_8542203 0.48 ENSDART00000158873

chr8_-_18316482 0.48 ENSDART00000190156
ring finger protein 220b
chr6_-_49078263 0.48 ENSDART00000032982
solute carrier family 5 (iodide transporter), member 8-like
chr13_+_3954540 0.47 ENSDART00000092646
leucine rich repeat containing 73
chr24_-_1356668 0.47 ENSDART00000188935
neuropilin 1a
chr21_-_45073764 0.47 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr6_+_60055168 0.46 ENSDART00000008752
phosphoenolpyruvate carboxykinase 1 (soluble)
chr13_+_36958086 0.46 ENSDART00000024386
FERM domain containing 6
chr23_-_27152866 0.46 ENSDART00000141305
si:dkey-157g16.6
chr21_-_5856050 0.46 ENSDART00000115367

chr18_-_3527988 0.46 ENSDART00000157669
calpain 5a
chr22_-_20814450 0.46 ENSDART00000089076
DOT1-like histone H3K79 methyltransferase
chr11_+_14147913 0.45 ENSDART00000022823
ENSDART00000154329
phospholipid phosphatase related 3b
chr4_+_38937575 0.45 ENSDART00000150385
zinc finger protein 997
chr18_+_48576527 0.44 ENSDART00000167555
potassium inwardly-rectifying channel, subfamily J, member 5
chr3_+_33745014 0.44 ENSDART00000159966
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a
chr19_-_28360033 0.43 ENSDART00000186994
si:dkey-261i16.5
chr11_+_3006124 0.42 ENSDART00000126071
copine Vb
chr17_-_1407593 0.42 ENSDART00000157622
ENSDART00000159458
zinc finger and BTB domain containing 42
chr10_-_13396720 0.41 ENSDART00000030976
interleukin 11 receptor, alpha
chr18_+_3530769 0.41 ENSDART00000163469
si:ch73-338a16.3
chr4_-_31700186 0.41 ENSDART00000183986
ENSDART00000180890
si:dkey-16p6.1
chr2_-_10703621 0.41 ENSDART00000005944
ribosomal protein L5a
chr2_-_12242695 0.40 ENSDART00000158175
G protein-coupled receptor 158b
chr23_+_30967686 0.39 ENSDART00000144485
si:ch211-197l9.2
chr9_+_14023386 0.39 ENSDART00000140199
ENSDART00000124267
si:ch211-67e16.4
chr14_-_29859067 0.39 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr7_+_17716601 0.38 ENSDART00000173792
ENSDART00000080825
reticulon 3
chr2_+_3516913 0.37 ENSDART00000109346

chr5_-_23855447 0.37 ENSDART00000051541
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
chr5_-_58112032 0.36 ENSDART00000016418
dopamine receptor D2b
chr15_+_26940569 0.35 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr17_+_5846202 0.35 ENSDART00000189713
fibronectin type III domain containing 4b
chr11_+_40657612 0.34 ENSDART00000183271
solute carrier family 45, member 1
chr18_+_6558146 0.34 ENSDART00000169401
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr11_-_23025949 0.34 ENSDART00000184859
ENSDART00000167818
ENSDART00000046122
ENSDART00000193120
ATPase plasma membrane Ca2+ transporting 2
chr23_-_11128601 0.33 ENSDART00000131232
contactin 3a, tandem duplicate 2
chr5_-_2672492 0.33 ENSDART00000192337

chr17_+_30587333 0.32 ENSDART00000156500
NHS-like 1a
chr22_-_14128716 0.32 ENSDART00000140323
si:ch211-246m6.4
chr22_+_26600834 0.32 ENSDART00000157411
adenylate cyclase 9
chr5_-_14564878 0.31 ENSDART00000160511
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr3_-_19091024 0.31 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr9_+_21407987 0.30 ENSDART00000145627
gap junction protein, alpha 3
chr16_-_31644545 0.30 ENSDART00000181634

chr7_+_4384863 0.29 ENSDART00000042955
ENSDART00000134653
slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3
chr24_-_6078222 0.29 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr17_-_7496341 0.29 ENSDART00000186907
si:ch211-278p9.3
chr9_-_20372977 0.28 ENSDART00000113418
immunoglobulin superfamily, member 3
chr8_-_18042089 0.28 ENSDART00000132596
iodothyronine deiodinase 1
chr7_-_66864756 0.27 ENSDART00000184462
ENSDART00000189424
adenosine monophosphate deaminase 3a
chr4_+_10366532 0.27 ENSDART00000189901
potassium voltage-gated channel, Shal-related subfamily, member 2
chr7_-_45076131 0.27 ENSDART00000110590
zgc:194678
chr14_-_10371638 0.27 ENSDART00000003879
family with sequence similarity 199, X-linked
chr24_+_24086249 0.27 ENSDART00000002953
lipase, member Ib
chr22_-_37611681 0.27 ENSDART00000028085
tetratricopeptide repeat domain 14
chr14_-_40389699 0.25 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr6_+_10094061 0.25 ENSDART00000150998
ENSDART00000162236
ATPase copper transporting beta
chr16_-_16481046 0.25 ENSDART00000158704
neurobeachin-like 2
chr17_+_34215886 0.24 ENSDART00000186775
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr24_-_8777781 0.24 ENSDART00000082362
ENSDART00000177400
male germ cell-associated kinase
chr14_+_29609245 0.24 ENSDART00000043058
si:dkey-34l15.2
chr5_+_7393346 0.24 ENSDART00000164238
si:ch73-72b7.1
chr3_+_56574623 0.23 ENSDART00000130877
Rac family small GTPase 1b
chr4_+_70967639 0.23 ENSDART00000159230
si:dkeyp-80d11.12
chr11_-_41130239 0.23 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr20_-_28642061 0.22 ENSDART00000135513
regulator of G protein signaling 6
chr23_+_31000243 0.21 ENSDART00000085263
selenoprotein I
chr18_+_6558338 0.21 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr11_-_45216684 0.20 ENSDART00000168621
transmembrane channel-like 8
chr8_+_45294767 0.20 ENSDART00000191527
ubiquitin associated protein 2b
chr23_-_14057191 0.20 ENSDART00000154908
adenylate cyclase 6a
chr8_-_7078575 0.19 ENSDART00000137413
si:ch73-233m11.2
chr8_+_26226044 0.19 ENSDART00000186503
WD repeat domain 6
chr23_+_24989387 0.19 ENSDART00000172299
ENSDART00000145307
Rho GTPase activating protein 4a
chr20_+_27194833 0.18 ENSDART00000150072
si:dkey-85n7.8
chr17_-_20558961 0.17 ENSDART00000155993
SH3 and PX domains 2Ab
chr23_+_34005792 0.17 ENSDART00000132668
si:ch211-207e14.4
chr14_-_48961056 0.17 ENSDART00000124192
si:dkeyp-121d2.7
chr25_-_35106751 0.16 ENSDART00000180682
ENSDART00000073457
zgc:194989
chr6_+_40922572 0.16 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_-_3372259 0.16 ENSDART00000140482
si:dkey-46g23.1
chr18_+_22994427 0.15 ENSDART00000173131
ENSDART00000172995
ENSDART00000172923
ENSDART00000141521
ENSDART00000173201
ENSDART00000059961
core-binding factor, beta subunit
chr11_+_30162407 0.15 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr5_+_20693724 0.14 ENSDART00000141368
si:ch211-240b21.2
chr21_-_38582061 0.14 ENSDART00000193891
ENSDART00000124349
POF1B, actin binding protein
chr8_-_47800754 0.14 ENSDART00000115050
ENSDART00000133669
KN motif and ankyrin repeat domains 3
chr11_+_14287427 0.14 ENSDART00000180903
si:ch211-262i1.3
chr25_+_19955598 0.13 ENSDART00000091547
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr23_-_27015160 0.13 ENSDART00000189028

chr14_+_25465346 0.12 ENSDART00000173436
si:dkey-280e21.3
chr21_-_22951604 0.12 ENSDART00000083449
ENSDART00000180129
duboraya
chr23_+_31979602 0.12 ENSDART00000140351
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_+_25783801 0.11 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr13_+_33689740 0.10 ENSDART00000161904
epoxide hydrolase 5
chr22_+_31207799 0.10 ENSDART00000133267
glutamate receptor interacting protein 2b
chrM_+_8894 0.10 ENSDART00000093611
ATP synthase 8, mitochondrial
chr20_+_18994465 0.10 ENSDART00000152778
L-threonine dehydrogenase
chr20_-_25669813 0.09 ENSDART00000153118
si:dkeyp-117h8.2
chr17_+_53294228 0.09 ENSDART00000158172
si:ch1073-416d2.3
chr7_+_3158104 0.09 ENSDART00000058348

chr13_-_38039871 0.09 ENSDART00000140645

chr5_+_19320554 0.09 ENSDART00000165119
RUN and SH3 domain containing 2
chr3_+_2669813 0.09 ENSDART00000014205

chr17_-_7473890 0.08 ENSDART00000192910
si:ch211-278p9.2
chr21_-_21580197 0.08 ENSDART00000143381
odorant receptor, family H, subfamily 133, member 3
chr12_+_17933775 0.08 ENSDART00000186047
ENSDART00000160586
transformation/transcription domain-associated protein
chr15_+_26941063 0.08 ENSDART00000149957
breast carcinoma amplified sequence 3
chrM_+_9052 0.08 ENSDART00000093612
ATP synthase 6, mitochondrial
chr2_+_26656283 0.07 ENSDART00000133202
ENSDART00000099208
aspartate beta-hydroxylase
chr10_+_39248911 0.06 ENSDART00000170079
ENSDART00000167974
FAD-dependent oxidoreductase domain containing 1
chr9_-_3519717 0.06 ENSDART00000145043
ddb1 and cul4 associated factor 17
chr4_-_36792144 0.06 ENSDART00000159147
si:dkeyp-87d1.1
chr8_+_35356944 0.06 ENSDART00000143243
si:dkeyp-14d3.1
chr20_-_45060241 0.06 ENSDART00000185227
kelch-like family member 29
chr17_-_5769196 0.05 ENSDART00000113885
si:dkey-100n19.2
chr16_+_54263921 0.05 ENSDART00000002856
dopamine receptor D2 like

Network of associatons between targets according to the STRING database.

First level regulatory network of zic2a+zic2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.3 1.1 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 1.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 1.0 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2 0.6 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.3 GO:0042311 vasodilation(GO:0042311)
0.2 1.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.6 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 1.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 1.0 GO:2000095 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.5 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 1.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.8 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 1.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.8 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.8 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.5 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.2 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 2.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 2.3 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0032438 melanosome organization(GO:0032438)
0.0 1.9 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 3.5 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.5 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 0.1 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.2 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0044609 DBIRD complex(GO:0044609)
0.2 1.8 GO:0016586 RSC complex(GO:0016586)
0.2 1.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 0.9 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 3.1 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.3 1.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 1.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.3 1.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.5 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.6 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 2.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.3 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.8 GO:0016918 retinal binding(GO:0016918)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.5 GO:0048018 death receptor binding(GO:0005123) receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 1.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.2 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins