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PRJEB1986: zebrafish developmental stages transcriptome

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Results for zbtb7b

Z-value: 0.62

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Transcription factors associated with zbtb7b

Gene Symbol Gene ID Gene Info
ENSDARG00000021891 zinc finger and BTB domain containing 7B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb7bdr11_v1_chr16_-_54810464_548104640.652.6e-03Click!

Activity profile of zbtb7b motif

Sorted Z-values of zbtb7b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16764751 4.23 ENSDART00000113862
zgc:174154
chr1_-_59571758 2.41 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr7_+_19552381 2.29 ENSDART00000169060
si:ch211-212k18.5
chr7_-_54677143 1.87 ENSDART00000163748
cyclin D1
chr16_-_31435020 1.86 ENSDART00000138508
zgc:194210
chr25_-_37331513 1.59 ENSDART00000111862
low density lipoprotein receptor class A domain containing 3
chr3_-_16289826 1.49 ENSDART00000131972
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr17_-_8312923 1.45 ENSDART00000064678
lefty2
chr11_-_30138299 1.29 ENSDART00000172106
Scm polycomb group protein like 2
chr1_+_15062 1.28 ENSDART00000169005
centrosomal protein 97
chr13_-_25198025 1.28 ENSDART00000159585
ENSDART00000144227
adenosine kinase a
chr7_+_26029672 1.28 ENSDART00000101126
arachidonate 12-lipoxygenase
chr6_-_43092175 1.17 ENSDART00000084389
leucine rich repeat neuronal 1
chr22_+_10090673 1.15 ENSDART00000186680
si:dkey-102c8.3
chr19_-_2318391 1.09 ENSDART00000012791
sp8 transcription factor a
chr1_+_14454663 1.09 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr12_-_990149 1.05 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr14_-_9522364 1.04 ENSDART00000054689
atonal bHLH transcription factor 8
chr14_+_45596583 1.03 ENSDART00000110429
zgc:194285
chr13_-_45523026 1.00 ENSDART00000020663
Rh blood group, D antigen
chr2_+_24374669 0.97 ENSDART00000133818
nuclear receptor subfamily 2, group F, member 6a
chr8_-_23776399 0.97 ENSDART00000114800
si:ch211-163l21.4
chr22_-_20403194 0.96 ENSDART00000010048
mitogen-activated protein kinase kinase 2a
chr21_-_18932761 0.96 ENSDART00000140129
mediator complex subunit 15
chr5_+_36899691 0.95 ENSDART00000132322
heterogeneous nuclear ribonucleoprotein L
chr1_+_59538755 0.93 ENSDART00000166354
Sp6 transcription factor
chr20_-_9194257 0.93 ENSDART00000133012
YLP motif containing 1
chr22_-_7050 0.91 ENSDART00000127829
ATPase family, AAA domain containing 3
chr1_+_594736 0.89 ENSDART00000166731
junctional adhesion molecule 2a
chr16_-_34212912 0.89 ENSDART00000145017
phosphatase and actin regulator 4b
chr23_-_44848961 0.88 ENSDART00000136839
wu:fb72h05
chr2_+_24374305 0.82 ENSDART00000022379
nuclear receptor subfamily 2, group F, member 6a
chr1_-_59216197 0.81 ENSDART00000062426
lysophosphatidic acid receptor 2b
chr18_+_30370339 0.81 ENSDART00000158871
Gse1 coiled-coil protein
chr21_+_15601100 0.79 ENSDART00000180558
ENSDART00000145454
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr16_+_54875530 0.78 ENSDART00000149795
nuclear receptor subfamily 0, group B, member 2a
chr20_-_21672970 0.78 ENSDART00000133286
si:ch211-207i1.2
chr21_-_28901095 0.77 ENSDART00000180820
CXXC finger protein 5a
chr5_+_36900157 0.75 ENSDART00000183533
ENSDART00000051184
heterogeneous nuclear ribonucleoprotein L
chr1_+_51475094 0.75 ENSDART00000146352
Meis homeobox 1 a
chr1_-_20970266 0.73 ENSDART00000088545
kelch-like family member 2
chr10_+_22034477 0.73 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr7_+_39401388 0.73 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr1_+_594584 0.72 ENSDART00000135944
junctional adhesion molecule 2a
chr19_-_47555956 0.71 ENSDART00000114549
actin, alpha, cardiac muscle 1a
chr18_+_30370559 0.71 ENSDART00000165450
Gse1 coiled-coil protein
chr21_+_28747069 0.70 ENSDART00000014058
zgc:100829
chr17_-_43287290 0.70 ENSDART00000156885
si:dkey-1f12.3
chr1_+_29741843 0.69 ENSDART00000136066
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr2_+_43469241 0.68 ENSDART00000142078
ENSDART00000098265
neuropilin 1b
chr5_-_35264517 0.68 ENSDART00000114981
pentatricopeptide repeat domain 2
chr13_-_51922290 0.67 ENSDART00000168648
serum response factor b
chr22_-_506522 0.67 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr20_+_35058634 0.67 ENSDART00000122696
heterogeneous nuclear ribonucleoprotein Ub
chr22_+_413349 0.67 ENSDART00000082453
cadherin, EGF LAG seven-pass G-type receptor 2
chr6_-_53326421 0.65 ENSDART00000191740
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr20_-_54435287 0.65 ENSDART00000148632
YY1 transcription factor b
chr12_+_10443785 0.63 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr14_-_16423200 0.63 ENSDART00000108868
ENSDART00000161793
mastermind-like transcriptional coactivator 1
chr4_-_25812329 0.60 ENSDART00000146658
transmembrane and coiled-coil domain family 3
chr11_+_44548209 0.59 ENSDART00000181798
ENSDART00000191742
ENSDART00000168209
nidogen 1b
chr25_-_34284144 0.59 ENSDART00000188109
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_11878099 0.58 ENSDART00000188314
WAS/WASL interacting protein family, member 2a
chr19_+_4912817 0.58 ENSDART00000101658
ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_-_23643751 0.58 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr17_+_53418445 0.58 ENSDART00000097631
solute carrier family 9 member A1b
chr7_-_57332915 0.58 ENSDART00000162653

chr22_-_367569 0.57 ENSDART00000041895
SSU72 homolog, RNA polymerase II CTD phosphatase
chr20_-_29483514 0.57 ENSDART00000062370
actin, alpha, cardiac muscle 1a
chr3_-_4501026 0.57 ENSDART00000163052
zgc:162198
chr9_-_264173 0.57 ENSDART00000166231
ENSDART00000165585
poly(rC) binding protein 2
chr24_+_27023616 0.57 ENSDART00000089541
disco-interacting protein 2 homolog Ca
chr20_+_39250673 0.56 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr17_+_26965351 0.55 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr21_-_45086170 0.54 ENSDART00000188963
Rap guanine nucleotide exchange factor (GEF) 6
chr5_-_41142768 0.53 ENSDART00000074789
zinc finger RNA binding protein
chr20_-_25631256 0.53 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_-_2707048 0.53 ENSDART00000166112
interleukin 6 (interferon, beta 2)
chr5_-_41142467 0.53 ENSDART00000129415
zinc finger RNA binding protein
chr4_-_77551860 0.52 ENSDART00000188176

chr6_+_36821621 0.52 ENSDART00000104157
transmembrane protein 45a
chr23_+_39346930 0.51 ENSDART00000102843
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr18_+_46151505 0.51 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr8_-_7444155 0.51 ENSDART00000148993
histone deacetylase 6
chr22_-_21046843 0.51 ENSDART00000133982
single stranded DNA binding protein 4
chr6_+_28203 0.50 ENSDART00000191561

chr24_+_37825634 0.50 ENSDART00000129889
intraflagellar transport 140 homolog (Chlamydomonas)
chr19_+_18903533 0.50 ENSDART00000157523
ENSDART00000166562
solute carrier family 39 (zinc transporter), member 7
chr22_-_21046654 0.49 ENSDART00000064902
single stranded DNA binding protein 4
chr4_-_2380173 0.48 ENSDART00000177727
nucleosome assembly protein 1-like 1
chr21_+_249970 0.48 ENSDART00000169026
Janus kinase 2a
chr6_+_584632 0.48 ENSDART00000151150
zgc:92360
chr16_-_12470034 0.46 ENSDART00000147483
eph receptor B6
chr9_-_8314028 0.46 ENSDART00000102739
si:ch211-145c1.1
chr14_-_15154695 0.46 ENSDART00000160677
UV-stimulated scaffold protein A
chr8_-_53488832 0.45 ENSDART00000191801
choline dehydrogenase
chr8_-_52938439 0.45 ENSDART00000168185
nuclear receptor subfamily 6, group A, member 1a
chr13_+_23214100 0.44 ENSDART00000163393
sorbin and SH3 domain containing 1
chr10_-_25657506 0.44 ENSDART00000110751
T cell lymphoma invasion and metastasis 1a
chr19_-_11237125 0.44 ENSDART00000163921
signal sequence receptor, beta
chr4_-_68569527 0.43 ENSDART00000192091

chr24_+_42131564 0.43 ENSDART00000153854
WW domain containing E3 ubiquitin protein ligase 1
chr14_+_109016 0.42 ENSDART00000158405
glypican 2
chr3_-_29891456 0.42 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr21_+_28747236 0.41 ENSDART00000137874
zgc:100829
chr5_-_22619879 0.41 ENSDART00000051623
zgc:113208
chr1_+_44196236 0.40 ENSDART00000179560
ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr4_+_357810 0.39 ENSDART00000163436
ENSDART00000103645
transmembrane protein 181
chr21_-_25416391 0.39 ENSDART00000114081
spermine synthase
chr4_-_77563411 0.38 ENSDART00000186841

chr12_-_14211293 0.38 ENSDART00000158399
AVL9 homolog (S. cerevisiase)
chr23_+_39346774 0.38 ENSDART00000190985
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr23_+_36101185 0.38 ENSDART00000103139
homeobox C8a
chr21_-_11646878 0.37 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr17_-_2721336 0.37 ENSDART00000109582
ENSDART00000192691
ENSDART00000189381
spermatogenesis associated 7
chr17_+_43946269 0.36 ENSDART00000017376
kinectin 1
chr6_+_52247993 0.36 ENSDART00000172176
zinc finger CCCH-type containing 10
chr18_-_41161828 0.35 ENSDART00000114993

chr16_-_24605969 0.35 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr7_+_67252880 0.35 ENSDART00000124969
polycystic kidney disease 1 like 2b
chr9_+_51891 0.34 ENSDART00000163529
zgc:158316
chr4_+_11311315 0.33 ENSDART00000051792
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr8_+_8947623 0.32 ENSDART00000131215
solute carrier family 35 (UDP-galactose transporter), member 2
chr19_-_5058908 0.32 ENSDART00000130062
chromodomain helicase DNA binding protein 4a
chr25_+_150570 0.32 ENSDART00000170892
ADAM metallopeptidase domain 10b
chr22_+_26703026 0.32 ENSDART00000158756
CREB binding protein a
chr1_-_51474974 0.31 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr5_-_16351306 0.31 ENSDART00000168643

chr1_-_22834824 0.31 ENSDART00000043556
LIM domain binding 2b
chr11_-_3334248 0.30 ENSDART00000154314
ENSDART00000121861
peripherin
chr15_-_25198107 0.30 ENSDART00000159793
MAX network transcriptional repressor a
chr18_-_26715156 0.29 ENSDART00000142043
MALT paracaspase 3
chr19_-_6982272 0.29 ENSDART00000141913
ENSDART00000150957
zinc finger protein 384 like
chr5_+_37744625 0.29 ENSDART00000014031
D4, zinc and double PHD fingers family 2
chr23_+_22335407 0.29 ENSDART00000147696
RAP1 GTPase activating protein
chr14_+_31498439 0.29 ENSDART00000173281
PHD finger protein 6
chr11_-_23322182 0.28 ENSDART00000111289
KiSS-1 metastasis-suppressor
chr6_+_3334710 0.28 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr3_-_20982492 0.28 ENSDART00000055722
solute carrier family 35, member B1
chr13_-_24218795 0.28 ENSDART00000136217
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
chr24_-_36593876 0.27 ENSDART00000160901

chr22_-_5918670 0.27 ENSDART00000141373
si:rp71-36a1.1
chr25_-_35143360 0.27 ENSDART00000188033
zgc:165555
chr2_+_24781026 0.26 ENSDART00000145692
phosphodiesterase 4C, cAMP-specific a
chr13_-_4367083 0.26 ENSDART00000124716
si:dkeyp-121d4.3
chr3_+_18399315 0.25 ENSDART00000110842
ribosomal protein S2
chr1_-_46706639 0.24 ENSDART00000074519
karyopherin alpha 3 (importin alpha 4)
chr11_-_40504170 0.24 ENSDART00000165394
si:dkeyp-61b2.1
chr7_-_56835543 0.23 ENSDART00000010322
SUMO/sentrin peptidase family member, NEDD8 specific
chr24_-_21914276 0.23 ENSDART00000128687
C1q and TNF related 9
chr4_+_55758103 0.22 ENSDART00000185964

chr17_+_32500387 0.22 ENSDART00000018423
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr16_+_11029762 0.21 ENSDART00000091183
Ets2 repressor factor like 3
chr18_+_32780450 0.20 ENSDART00000168399
olfactory receptor C family, g7
chr6_+_23712911 0.20 ENSDART00000167795
zgc:158654
chr24_-_24060460 0.20 ENSDART00000142813
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr5_-_10012971 0.18 ENSDART00000179421

chr23_+_19691146 0.18 ENSDART00000143001
si:dkey-93l1.6
chr21_+_13577227 0.18 ENSDART00000146283
si:dkey-248f6.3
chr7_-_24236364 0.16 ENSDART00000010124
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr14_-_48245816 0.16 ENSDART00000172452
relaxin/insulin-like family peptide receptor 1
chr17_+_37310663 0.16 ENSDART00000157122
ELM2 and Myb/SANT-like domain containing 1b
chr19_+_41173386 0.16 ENSDART00000142773
ankyrin repeat and SOCS box containing 4
chr7_-_5711197 0.15 ENSDART00000134367
si:dkey-10h3.2
chr21_+_233271 0.15 ENSDART00000171440
DTW domain containing 2
chr20_-_16972351 0.15 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
chr18_+_33570170 0.15 ENSDART00000133276
si:dkey-47k20.3
chr16_+_23531583 0.15 ENSDART00000146708
adenosine deaminase, RNA-specific
chr10_-_5857548 0.15 ENSDART00000166933
si:ch211-281k19.2
chr1_-_44638058 0.15 ENSDART00000081835
solute carrier family 43 (amino acid system L transporter), member 1b
chr22_-_24900121 0.14 ENSDART00000147643
si:dkey-4c23.3
chr6_+_52212574 0.14 ENSDART00000025940
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr6_-_10788065 0.14 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr7_+_34453185 0.14 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
chr7_-_3860501 0.12 ENSDART00000191053
si:dkey-88n24.6
chr6_-_29377092 0.11 ENSDART00000078665
transmembrane protein 131
chr21_-_45871866 0.11 ENSDART00000161716
La ribonucleoprotein domain family, member 1
chr23_+_19182819 0.11 ENSDART00000131804
si:dkey-93l1.4
chr13_-_31435137 0.11 ENSDART00000057441
reticulon 1a
chr9_-_37637179 0.10 ENSDART00000188143
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr3_+_14388010 0.10 ENSDART00000171726
ENSDART00000165452
transmembrane protein 56b
chr22_-_6219674 0.09 ENSDART00000182582
si:ch211-274k16.2
chr12_+_47945664 0.09 ENSDART00000189824
ENSDART00000055743
ENSDART00000188936

chr14_+_24283915 0.09 ENSDART00000172868
kelch-like family member 3
chr2_-_44746723 0.09 ENSDART00000041806
acyl-CoA synthetase medium chain family member 3
chr23_-_19140781 0.09 ENSDART00000143580
si:ch73-381f5.2
chr2_+_54389750 0.09 ENSDART00000189236
RAB12, member RAS oncogene family
chr20_+_474288 0.09 ENSDART00000026794
5'-nucleotidase domain containing 1
chr14_-_22390821 0.09 ENSDART00000054396
F-box and leucine-rich repeat protein 3, like
chr9_+_29323163 0.09 ENSDART00000184908
oxoglutarate (alpha-ketoglutarate) receptor 1b
chr18_+_34362608 0.08 ENSDART00000131478
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr3_+_22079219 0.08 ENSDART00000122782
KAT8 regulatory NSL complex subunit 1b
chr13_+_41022502 0.08 ENSDART00000026808
dickkopf WNT signaling pathway inhibitor 1a
chr16_+_7991274 0.08 ENSDART00000179704
anoctamin 10a
chr4_-_22472653 0.08 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
lysine (K)-specific methyltransferase 2E
chr12_+_48841419 0.07 ENSDART00000125331
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr6_+_52212927 0.07 ENSDART00000143458
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr25_+_25172983 0.07 ENSDART00000103203
chemokine (C-C motif) ligand 35, duplicate 2
chr5_-_37247654 0.07 ENSDART00000112312
leucine-rich repeats and calponin homology (CH) domain containing 2
chr9_-_32191620 0.07 ENSDART00000139426
Pim proto-oncogene, serine/threonine kinase, related 143

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb7b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 1.0 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 0.9 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.3 1.1 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.2 1.3 GO:0044209 AMP salvage(GO:0044209)
0.2 1.3 GO:0003272 endocardial cushion formation(GO:0003272)
0.2 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.7 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 0.5 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.2 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.3 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.4 GO:0003128 heart field specification(GO:0003128)
0.1 0.7 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0006953 acute-phase response(GO:0006953)
0.1 0.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.7 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.7 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.6 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.3 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.6 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.7 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.7 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:1900117 regulation of execution phase of apoptosis(GO:1900117)
0.0 0.8 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.4 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 2.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 1.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.7 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 2.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.3 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.8 GO:0035060 brahma complex(GO:0035060)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 1.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 4.2 GO:0005764 lysosome(GO:0005764)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.0 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 1.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 2.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.3 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.9 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 4.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 3.1 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 2.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation